IMP
Process View
The network for 'positive regulation of skeletal muscle cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of skeletal muscle cell differentiation
Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Tbx5 | T-box 5 | 0.987 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.985 | |
| Tbx3 | T-box 3 | 0.984 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.980 | |
| Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.970 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.968 | |
| Hoxa1 | homeobox A1 | 0.932 | |
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.911 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.907 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.905 | |
| Cry1 | cryptochrome 1 (photolyase-like) | 0.902 | |
| Per2 | period homolog 2 (Drosophila) | 0.900 | |
| Clock | circadian locomotor output cycles kaput | 0.834 | |
| Foxg1 | forkhead box G1 | 0.816 | |
| Foxc1 | forkhead box C1 | 0.731 | |
| Prrx1 | paired related homeobox 1 | 0.729 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.726 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.726 | |
| Cry2 | cryptochrome 2 (photolyase-like) | 0.672 | |
| Msx1 | homeobox, msh-like 1 | 0.660 | |
| Shh | sonic hedgehog | 0.658 | |
| Pax2 | paired box gene 2 | 0.622 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.609 | |
| Sox2 | SRY-box containing gene 2 | 0.591 | |
| Sall4 | sal-like 4 (Drosophila) | 0.493 | |
| Tbx1 | T-box 1 | 0.492 | |
| Gja5 | gap junction protein, alpha 5 | 0.491 | |
| Sox9 | SRY-box containing gene 9 | 0.482 | |
| Cyp26a1 | cytochrome P450, family 26, subfamily a, polypeptide 1 | 0.463 | |
| Bmp4 | bone morphogenetic protein 4 | 0.447 | |
| Jag1 | jagged 1 | 0.421 | |
| Dlx5 | distal-less homeobox 5 | 0.414 | |
| Bmp5 | bone morphogenetic protein 5 | 0.409 | |
| Ighmbp2 | immunoglobulin mu binding protein 2 | 0.408 | |
| Pax3 | paired box gene 3 | 0.387 | |
| Wt1 | Wilms tumor 1 homolog | 0.362 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.358 | |
| Fgf10 | fibroblast growth factor 10 | 0.339 | |
| Efnb2 | ephrin B2 | 0.338 | |
| Alx1 | ALX homeobox 1 | 0.335 | |
| Cyp26c1 | cytochrome P450, family 26, subfamily c, polypeptide 1 | 0.326 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.308 | |
| Nog | noggin | 0.290 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.267 | |
| Bdnf | brain derived neurotrophic factor | 0.251 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.249 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.241 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.236 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.223 | |
| Cxadr | coxsackie virus and adenovirus receptor | 0.219 | |
| Irx3 | Iroquois related homeobox 3 (Drosophila) | 0.199 | |
| Gata6 | GATA binding protein 6 | 0.199 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.188 | |
| Runx2 | runt related transcription factor 2 | 0.173 | |
| Gata4 | GATA binding protein 4 | 0.169 | |
| Npas2 | neuronal PAS domain protein 2 | 0.162 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.160 | |
| Tcf21 | transcription factor 21 | 0.155 | |
| Sim1 | single-minded homolog 1 (Drosophila) | 0.154 | |
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.150 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.142 | |
| Trp63 | transformation related protein 63 | 0.138 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.135 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.132 | |
| Sall1 | sal-like 1 (Drosophila) | 0.126 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.125 | |
| Dlx2 | distal-less homeobox 2 | 0.114 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.114 | |
| Mn1 | meningioma 1 | 0.096 | |
| Xirp1 | xin actin-binding repeat containing 1 | 0.095 | |
| Dll4 | delta-like 4 (Drosophila) | 0.093 | |
| Shox2 | short stature homeobox 2 | 0.089 | |
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.088 | |
| Gata3 | GATA binding protein 3 | 0.087 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.087 | |
| Foxc2 | forkhead box C2 | 0.085 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.085 | |
| Tbx4 | T-box 4 | 0.084 | |
| Fgf8 | fibroblast growth factor 8 | 0.084 | |
| Rarb | retinoic acid receptor, beta | 0.082 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.075 | |
| Sox11 | SRY-box containing gene 11 | 0.074 | |
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.069 | |
| Bmp7 | bone morphogenetic protein 7 | 0.069 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.068 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.066 | |
| Hoxb2 | homeobox B2 | 0.063 | |
| Foxf1a | forkhead box F1a | 0.060 | |
| Osr1 | odd-skipped related 1 (Drosophila) | 0.060 | |
| Hmx3 | H6 homeobox 3 | 0.059 | |
| Gsc | goosecoid homeobox | 0.058 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.058 | |
| Ahr | aryl-hydrocarbon receptor | 0.058 | |
| Msc | musculin | 0.057 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.055 | |
| Prrx2 | paired related homeobox 2 | 0.054 | |
| Myf5 | myogenic factor 5 | 0.054 | |
| Nanog | Nanog homeobox | 0.052 | |
| Zfpm2 | zinc finger protein, multitype 2 | 0.052 | |
| Per1 | period homolog 1 (Drosophila) | 0.051 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| HDAC4 | histone deacetylase 4 | 0.995 | |
| HDAC9 | histone deacetylase 9 | 0.486 | |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.082 | |
| MEF2C | myocyte enhancer factor 2C | 0.056 | |
| EP300 | E1A binding protein p300 | 0.047 | |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.044 | |
| CLOCK | clock homolog (mouse) | 0.035 | |
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.024 | |
| EPAS1 | endothelial PAS domain protein 1 | 0.019 | |
| TCF4 | transcription factor 4 | 0.019 | |
| MIF4GD | MIF4G domain containing | 0.018 | |
| AHR | aryl hydrocarbon receptor | 0.017 | |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.016 | |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.010 |