The network for 'positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.

Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Gli3 GLI-Kruppel family member GLI3 0.999
Pax2 paired box gene 2 0.998
Eya1 eyes absent 1 homolog (Drosophila) 0.997
Tbx1 T-box 1 0.996
Rarg retinoic acid receptor, gamma 0.996
Foxc1 forkhead box C1 0.991
Pax3 paired box gene 3 0.990
Msx1 homeobox, msh-like 1 0.987
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.980
Hoxa1 homeobox A1 0.975
Fgf10 fibroblast growth factor 10 0.971
Dlx5 distal-less homeobox 5 0.971
Fgf8 fibroblast growth factor 8 0.966
Foxc2 forkhead box C2 0.959
Hand1 heart and neural crest derivatives expressed transcript 1 0.958
Lhx1 LIM homeobox protein 1 0.940
Lmx1a LIM homeobox transcription factor 1 alpha 0.932
Pax8 paired box gene 8 0.930
Tcfap2a transcription factor AP-2, alpha 0.915
Bmp7 bone morphogenetic protein 7 0.912
Prrx1 paired related homeobox 1 0.907
Otx2 orthodenticle homolog 2 (Drosophila) 0.905
Bmp4 bone morphogenetic protein 4 0.903
Gli2 GLI-Kruppel family member GLI2 0.879
Fgfr1 fibroblast growth factor receptor 1 0.858
Pitx2 paired-like homeodomain transcription factor 2 0.840
Rarb retinoic acid receptor, beta 0.820
Gbx2 gastrulation brain homeobox 2 0.795
Ret ret proto-oncogene 0.793
Emx2 empty spiracles homolog 2 (Drosophila) 0.788
Sox9 SRY-box containing gene 9 0.770
Chrd chordin 0.748
Nog noggin 0.708
Zeb1 zinc finger E-box binding homeobox 1 0.701
Foxg1 forkhead box G1 0.687
Twist2 twist homolog 2 (Drosophila) 0.686
Smo smoothened homolog (Drosophila) 0.684
Rara retinoic acid receptor, alpha 0.670
Fgf3 fibroblast growth factor 3 0.669
Hoxa11 homeobox A11 0.667
Rxra retinoid X receptor alpha 0.623
Prrx2 paired related homeobox 2 0.600
Wnt1 wingless-related MMTV integration site 1 0.592
Wnt9b wingless-type MMTV integration site 9B 0.576
Hmx3 H6 homeobox 3 0.576
Wnt3a wingless-related MMTV integration site 3A 0.567
Hoxa2 homeobox A2 0.535
Hoxa3 homeobox A3 0.524
Wt1 Wilms tumor 1 homolog 0.523
Nos3 nitric oxide synthase 3, endothelial cell 0.495
Hand2 heart and neural crest derivatives expressed transcript 2 0.451
Vangl2 vang-like 2 (van gogh, Drosophila) 0.445
Pax1 paired box gene 1 0.432
Col2a1 collagen, type II, alpha 1 0.427
Jag1 jagged 1 0.425
Hoxd11 homeobox D11 0.423
Hoxd3 homeobox D3 0.419
Otx1 orthodenticle homolog 1 (Drosophila) 0.415
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.411
Chd7 chromodomain helicase DNA binding protein 7 0.395
Gsc goosecoid homeobox 0.382
Foxd2 forkhead box D2 0.378
Isl1 ISL1 transcription factor, LIM/homeodomain 0.361
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.340
Six2 sine oculis-related homeobox 2 homolog (Drosophila) 0.328
Msx2 homeobox, msh-like 2 0.328
Sox2 SRY-box containing gene 2 0.312
Hoxb3 homeobox B3 0.309
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.306
Alx4 aristaless-like homeobox 4 0.304
Fgfr3 fibroblast growth factor receptor 3 0.297
Hoxb1 homeobox B1 0.296
Gata3 GATA binding protein 3 0.293
Runx2 runt related transcription factor 2 0.286
Foxi1 forkhead box I1 0.253
Lmx1b LIM homeobox transcription factor 1 beta 0.234
Bcl2 B-cell leukemia/lymphoma 2 0.226
Ctnnb1 catenin (cadherin associated protein), beta 1 0.225
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.219
Lef1 lymphoid enhancer binding factor 1 0.214
Lhx3 LIM homeobox protein 3 0.210
Gdnf glial cell line derived neurotrophic factor 0.205
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.201
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.198
Sox10 SRY-box containing gene 10 0.197
Hoxd13 homeobox D13 0.190
Tgfb2 transforming growth factor, beta 2 0.182
Wnt6 wingless-related MMTV integration site 6 0.180
Sspo SCO-spondin 0.174
Alx3 aristaless-like homeobox 3 0.174
Gdf11 growth differentiation factor 11 0.173
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.172
Vax1 ventral anterior homeobox containing gene 1 0.171
Ednra endothelin receptor type A 0.171
T brachyury 0.171
Phox2b paired-like homeobox 2b 0.156
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.147
Hoxd9 homeobox D9 0.146
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
HIST1H2BD histone cluster 1, H2bd 0.025
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism