Process View
The network for 'metanephros morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The process in which the anatomical structures of the metanephros are generated and organized.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Pax2 | paired box gene 2 | 1.000 | |
Shh | sonic hedgehog | 1.000 | |
Gli3 | GLI-Kruppel family member GLI3 | 1.000 | |
Otx2 | orthodenticle homolog 2 (Drosophila) | 1.000 | |
Pitx2 | paired-like homeodomain transcription factor 2 | 1.000 | |
Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
Fgf8 | fibroblast growth factor 8 | 1.000 | |
Foxc1 | forkhead box C1 | 1.000 | |
Pax3 | paired box gene 3 | 0.999 | |
Lhx1 | LIM homeobox protein 1 | 0.998 | |
Emx2 | empty spiracles homolog 2 (Drosophila) | 0.997 | |
Pax8 | paired box gene 8 | 0.996 | |
Gli2 | GLI-Kruppel family member GLI2 | 0.994 | |
Rarg | retinoic acid receptor, gamma | 0.994 | |
Foxc2 | forkhead box C2 | 0.994 | |
Sox2 | SRY-box containing gene 2 | 0.993 | |
Fgfr1 | fibroblast growth factor receptor 1 | 0.985 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.979 | |
Otx1 | orthodenticle homolog 1 (Drosophila) | 0.973 | |
Nog | noggin | 0.972 | |
Fgf10 | fibroblast growth factor 10 | 0.972 | |
Lhx3 | LIM homeobox protein 3 | 0.965 | |
Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.965 | |
Sall4 | sal-like 4 (Drosophila) | 0.964 | |
Eya1 | eyes absent 1 homolog (Drosophila) | 0.962 | |
Hoxd11 | homeobox D11 | 0.944 | |
Bmp4 | bone morphogenetic protein 4 | 0.940 | |
Gdnf | glial cell line derived neurotrophic factor | 0.934 | |
Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.928 | |
Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.921 | |
Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.920 | |
Pax6 | paired box gene 6 | 0.914 | |
Nodal | nodal | 0.911 | |
Ret | ret proto-oncogene | 0.904 | |
Meox2 | mesenchyme homeobox 2 | 0.901 | |
Wt1 | Wilms tumor 1 homolog | 0.886 | |
Rarb | retinoic acid receptor, beta | 0.877 | |
Tbx1 | T-box 1 | 0.875 | |
Lmx1b | LIM homeobox transcription factor 1 beta | 0.871 | |
Gbx2 | gastrulation brain homeobox 2 | 0.869 | |
Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.863 | |
Fgf3 | fibroblast growth factor 3 | 0.853 | |
En1 | engrailed 1 | 0.849 | |
Tbx3 | T-box 3 | 0.817 | |
T | brachyury | 0.805 | |
Hoxa11 | homeobox A11 | 0.794 | |
Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.784 | |
Pou3f3 | POU domain, class 3, transcription factor 3 | 0.781 | |
Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.776 | |
Hoxd13 | homeobox D13 | 0.721 | |
Wnt3a | wingless-related MMTV integration site 3A | 0.716 | |
Dlx5 | distal-less homeobox 5 | 0.704 | |
Ren1 | renin 1 structural | 0.703 | |
Zic3 | zinc finger protein of the cerebellum 3 | 0.700 | |
Tgfb2 | transforming growth factor, beta 2 | 0.675 | |
Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.672 | |
Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.672 | |
Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.665 | |
Kiss1 | KiSS-1 metastasis-suppressor | 0.661 | |
Wnt4 | wingless-related MMTV integration site 4 | 0.658 | |
Esr1 | estrogen receptor 1 (alpha) | 0.641 | |
Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.633 | |
Msx1 | homeobox, msh-like 1 | 0.616 | |
Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.616 | |
Tcfap2a | transcription factor AP-2, alpha | 0.612 | |
Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.569 | |
Smo | smoothened homolog (Drosophila) | 0.548 | |
Lef1 | lymphoid enhancer binding factor 1 | 0.546 | |
Msx2 | homeobox, msh-like 2 | 0.538 | |
Prrx1 | paired related homeobox 1 | 0.532 | |
Ntf3 | neurotrophin 3 | 0.501 | |
Alx4 | aristaless-like homeobox 4 | 0.484 | |
Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.469 | |
Hoxa2 | homeobox A2 | 0.463 | |
Twist2 | twist homolog 2 (Drosophila) | 0.457 | |
Emx1 | empty spiracles homolog 1 (Drosophila) | 0.457 | |
Lmx1a | LIM homeobox transcription factor 1 alpha | 0.454 | |
Tbx2 | T-box 2 | 0.447 | |
Vegfa | vascular endothelial growth factor A | 0.436 | |
Hoxa13 | homeobox A13 | 0.435 | |
Tcf15 | transcription factor 15 | 0.431 | |
Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.408 | |
Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.403 | |
Bmpr1b | bone morphogenetic protein receptor, type 1B | 0.396 | |
Sox9 | SRY-box containing gene 9 | 0.379 | |
Nab2 | Ngfi-A binding protein 2 | 0.379 | |
Hoxa3 | homeobox A3 | 0.375 | |
Rara | retinoic acid receptor, alpha | 0.374 | |
Foxg1 | forkhead box G1 | 0.367 | |
Fgf9 | fibroblast growth factor 9 | 0.363 | |
Neurog3 | neurogenin 3 | 0.357 | |
Lepr | leptin receptor | 0.353 | |
Bmp7 | bone morphogenetic protein 7 | 0.344 | |
Zic2 | zinc finger protein of the cerebellum 2 | 0.332 | |
Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.329 | |
Gli1 | GLI-Kruppel family member GLI1 | 0.328 | |
Bcl2 | B-cell leukemia/lymphoma 2 | 0.324 | |
Nkx2-1 | NK2 homeobox 1 | 0.324 | |
Ar | androgen receptor | 0.322 | |
Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.316 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.633 | |
EGR3 | early growth response 3 | 0.404 | |
FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.217 | |
BMPR1A | bone morphogenetic protein receptor, type IA | 0.202 | |
FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.142 | |
EGR1 | early growth response 1 | 0.111 | |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.098 | |
IER2 | immediate early response 2 | 0.090 | |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.073 | |
CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.059 | |
CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.055 | |
CCNE1 | cyclin E1 | 0.043 | |
NKX2-1 | NK2 homeobox 1 | 0.040 | |
EGR2 | early growth response 2 | 0.039 | |
TRPV5 | transient receptor potential cation channel, subfamily V, member 5 | 0.038 | |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.035 | |
MEOX1 | mesenchyme homeobox 1 | 0.032 | |
CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.026 | |
FBXW11 | F-box and WD repeat domain containing 11 | 0.025 | |
FSTL1 | follistatin-like 1 | 0.021 | |
SOX2 | SRY (sex determining region Y)-box 2 | 0.019 | |
PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.017 | |
CDK2 | cyclin-dependent kinase 2 | 0.015 | |
JUNB | jun B proto-oncogene | 0.013 | |
UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.013 | |
TCF4 | transcription factor 4 | 0.013 | |
TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.012 | |
TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.011 | |
JUN | jun proto-oncogene | 0.011 | |
LAT | linker for activation of T cells | 0.011 | |
COL2A1 | collagen, type II, alpha 1 | 0.011 | |
CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.011 | |
TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.011 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
LOC100365106 | rCG32755-like | 0.610 | |
Trhr2 | thyrotropin releasing hormone receptor 2 | 0.177 | |
Gata3 | GATA binding protein 3 | 0.100 | |
C4b | complement component 4B (Chido blood group) | 0.095 | |
Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.082 | |
Rnf213 | ring finger protein 213 | 0.073 | |
Hoxb7 | homeo box B7 | 0.063 | |
Il1r1 | interleukin 1 receptor, type I | 0.055 | |
Lhx1 | LIM homeobox 1 | 0.048 | |
LOC100362108 | poly (ADP-ribose) polymerase family, member 10 | 0.038 | |
Spon1 | spondin 1, extracellular matrix protein | 0.033 | |
Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.032 | |
Ltbp3 | latent transforming growth factor beta binding protein 3 | 0.030 | |
Ddr1 | discoidin domain receptor tyrosine kinase 1 | 0.028 | |
Mpp3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) | 0.027 | |
Nek9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.027 | |
Cxxc4 | CXXC finger 4 | 0.026 | |
Dtx3l | deltex 3-like (Drosophila) | 0.025 | |
Lama5 | laminin, alpha 5 | 0.025 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.024 | |
Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.024 | |
Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.022 | |
Prph2 | peripherin 2 | 0.021 | |
Gjd2 | gap junction protein, delta 2 | 0.021 | |
Hoxc4 | homeo box C4 | 0.021 | |
Chgb | chromogranin B | 0.020 | |
Gper | G protein-coupled estrogen receptor 1 | 0.020 | |
Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.019 | |
Aebp1 | AE binding protein 1 | 0.019 | |
Dbh | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 0.018 | |
Pou2f2 | POU class 2 homeobox 2 | 0.018 | |
Prdm2 | PR domain containing 2, with ZNF domain | 0.017 | |
Il6st | interleukin 6 signal transducer | 0.017 | |
Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.016 | |
Bcl2 | B-cell CLL/lymphoma 2 | 0.015 | |
Rps6ka1 | ribosomal protein S6 kinase polypeptide 1 | 0.014 | |
Igtp | interferon gamma induced GTPase | 0.014 | |
MGC108823 | similar to interferon-inducible GTPase | 0.014 | |
Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.013 | |
Efna5 | ephrin A5 | 0.013 | |
Ddr2 | discoidin domain receptor tyrosine kinase 2 | 0.013 | |
Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.013 | |
Grip2 | glutamate receptor interacting protein 2 | 0.012 | |
Rara | retinoic acid receptor, alpha | 0.012 | |
Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.012 | |
Clec11a | C-type lectin domain family 11, member a | 0.012 | |
Acacb | acetyl-Coenzyme A carboxylase beta | 0.012 | |
Nr5a2 | nuclear receptor subfamily 5, group A, member 2 | 0.012 | |
Sp110 | SP110 nuclear body protein | 0.011 | |
Nrg2 | neuregulin 2 | 0.011 | |
Srd5a2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 0.011 | |
Rxra | retinoid X receptor alpha | 0.011 | |
Trim5 | tripartite motif-containing 5 | 0.010 | |
Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | 0.010 |