The network for 'hindbrain morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hindbrain morphogenesis

The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.

Mus musculus
Name Description Probability Func Analog Organism
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Shh sonic hedgehog 0.999
Emx1 empty spiracles homolog 1 (Drosophila) 0.998
Pax2 paired box gene 2 0.998
Emx2 empty spiracles homolog 2 (Drosophila) 0.995
En1 engrailed 1 0.993
Fgfr1 fibroblast growth factor receptor 1 0.990
Lhx1 LIM homeobox protein 1 0.989
Gbx2 gastrulation brain homeobox 2 0.988
Fgf8 fibroblast growth factor 8 0.985
Pax6 paired box gene 6 0.981
Hoxa1 homeobox A1 0.977
Lhx3 LIM homeobox protein 3 0.975
Chrd chordin 0.975
Eya1 eyes absent 1 homolog (Drosophila) 0.973
Phox2b paired-like homeobox 2b 0.973
Isl1 ISL1 transcription factor, LIM/homeodomain 0.957
Hoxa2 homeobox A2 0.953
Nrxn1 neurexin I 0.946
Rarg retinoic acid receptor, gamma 0.940
Wnt1 wingless-related MMTV integration site 1 0.930
Foxc1 forkhead box C1 0.913
Lmx1b LIM homeobox transcription factor 1 beta 0.910
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.907
Lmx1a LIM homeobox transcription factor 1 alpha 0.898
Otx1 orthodenticle homolog 1 (Drosophila) 0.893
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.888
Foxc2 forkhead box C2 0.874
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.867
Lhx5 LIM homeobox protein 5 0.864
Sox2 SRY-box containing gene 2 0.862
Msx1 homeobox, msh-like 1 0.855
C1qa complement component 1, q subcomponent, alpha polypeptide 0.842
Nog noggin 0.842
Pax3 paired box gene 3 0.841
Dlx5 distal-less homeobox 5 0.838
Hoxd3 homeobox D3 0.837
Hand2 heart and neural crest derivatives expressed transcript 2 0.836
Hes1 hairy and enhancer of split 1 (Drosophila) 0.827
Gdnf glial cell line derived neurotrophic factor 0.818
Rarb retinoic acid receptor, beta 0.812
Tbx1 T-box 1 0.793
C1qc complement component 1, q subcomponent, C chain 0.790
Msx2 homeobox, msh-like 2 0.780
Prrx1 paired related homeobox 1 0.778
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.772
Pax8 paired box gene 8 0.768
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.755
Bmp7 bone morphogenetic protein 7 0.753
Neurod1 neurogenic differentiation 1 0.730
Ctnnb1 catenin (cadherin associated protein), beta 1 0.724
Hes5 hairy and enhancer of split 5 (Drosophila) 0.715
Pou3f3 POU domain, class 3, transcription factor 3 0.701
Hoxa3 homeobox A3 0.697
Hoxd11 homeobox D11 0.696
Tbx3 T-box 3 0.688
Nfib nuclear factor I/B 0.686
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.670
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.666
C1qb complement component 1, q subcomponent, beta polypeptide 0.664
Hoxb2 homeobox B2 0.645
Pitx2 paired-like homeodomain transcription factor 2 0.637
Bdnf brain derived neurotrophic factor 0.636
Smo smoothened homolog (Drosophila) 0.634
Gli2 GLI-Kruppel family member GLI2 0.618
Nrxn3 neurexin III 0.615
Tcfap2a transcription factor AP-2, alpha 0.613
Cdon cell adhesion molecule-related/down-regulated by oncogenes 0.600
Wt1 Wilms tumor 1 homolog 0.559
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.551
Grid2 glutamate receptor, ionotropic, delta 2 0.547
Neurog2 neurogenin 2 0.541
Wnt3a wingless-related MMTV integration site 3A 0.523
Gsk3b glycogen synthase kinase 3 beta 0.523
Pten phosphatase and tensin homolog 0.516
T brachyury 0.493
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.488
Lef1 lymphoid enhancer binding factor 1 0.481
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.469
Prrx2 paired related homeobox 2 0.467
Wnt4 wingless-related MMTV integration site 4 0.458
Dlx6 distal-less homeobox 6 0.452
Hoxd13 homeobox D13 0.447
Bmp4 bone morphogenetic protein 4 0.446
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.438
Axin1 axin 1 0.436
Gucy2e guanylate cyclase 2e 0.419
Mecom MDS1 and EVI1 complex locus 0.418
Lhx9 LIM homeobox protein 9 0.395
Foxg1 forkhead box G1 0.395
Zeb1 zinc finger E-box binding homeobox 1 0.394
Hand1 heart and neural crest derivatives expressed transcript 1 0.391
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.383
Fgf10 fibroblast growth factor 10 0.382
Ednra endothelin receptor type A 0.382
Vegfa vascular endothelial growth factor A 0.371
Gsc goosecoid homeobox 0.356
Zic4 zinc finger protein of the cerebellum 4 0.342
Fgf15 fibroblast growth factor 15 0.342
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
hnf1ba HNF1 homeobox Ba 0.997
pax2a paired box gene 2a 0.993
fgf8a fibroblast growth factor 8 a 0.991
crabp2a cellular retinoic acid binding protein 2, a 0.974
gbx1 gastrulation brain homeobox 1 0.932
wnt1 wingless-type MMTV integration site family, member 1 0.910
raraa retinoic acid receptor, alpha a 0.909
ptf1a pancreas specific transcription factor, 1a 0.787
dlc deltaC 0.732
gbx2 gastrulation brain homeo box 2 0.708
wnt8b wingless-type MMTV integration site family, member 8b 0.702
neurog1 neurogenin 1 0.671
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.665
wnt4a wingless-type MMTV integration site family, member 4a 0.650
egr2b early growth response 2b 0.629
eng2b engrailed 2b 0.614
shha sonic hedgehog a 0.611
irx7 iroquois homeobox protein 7 0.598
hoxd3a homeo box D3a 0.567
irx4a iroquois homeobox protein 4a 0.532
fgf3 fibroblast growth factor 3 0.519
isl1 islet1 0.471
her8a hairy-related 8a 0.467
osr2 odd-skipped related 2 (Drosophila) 0.459
atoh1a atonal homolog 1a 0.440
gli1 GLI-Kruppel family member 1 0.434
wnt3 wingless-type MMTV integration site family, member 3 0.421
wnt5b wingless-type MMTV integration site family, member 5b 0.419
hoxb1b homeo box B1b 0.410
meis3 myeloid ecotropic viral integration site 3 0.398
foxd3 forkhead box D3 0.395
foxa2 forkhead box A2 0.381
alcama activated leukocyte cell adhesion molecule a 0.360
pax6b paired box gene 6b 0.359
wnt2 wingless-type MMTV integration site family member 2 0.341
lhx1a LIM homeobox 1a 0.340
otx2 orthodenticle homolog 2 0.339
sema3aa semaphorin 3aa 0.335
gdnf glial cell derived neurotrophic factor 0.333
tbx1 T-box 1 0.332
hmx4 H6 family homeobox 4 0.319
ascl1a achaete-scute complex-like 1a (Drosophila) 0.317
egr2a early growth response 2a 0.311
six2a sine oculis-related homeobox 2a 0.283
esrra estrogen-related receptor alpha 0.279
mab21l2 mab-21-like 2 0.275
nkx2.2a NK2 transcription factor related 2a 0.274
sp5l Sp5 transcription factor-like 0.266
irx4b iroquois homeobox protein 4b 0.265
hoxc4a homeo box C4a 0.258
sox10 SRY-box containing gene 10 0.256
hoxd4a homeo box D4a 0.256
cacnb4b calcium channel, voltage-dependent, beta 4b subunit 0.253
fgf10a fibroblast growth factor 10a 0.249
lhx1b LIM homeobox 1b 0.248
dbx1a developing brain homeobox 1a 0.237
dla deltaA 0.203
pax8 paired box gene 8 0.199
foxa1 forkhead box A1 0.197
hoxc6a homeo box C6a 0.196
pou3f3b POU class 3 homeobox 3b 0.186
barhl2 BarH-like 2 0.184
esr1 estrogen receptor 1 0.180
dlx4a distal-less homeobox gene 4a 0.174
her5 hairy-related 5 0.168
lef1 lymphocyte enhancer binding factor 1 0.167
twist3 twist3 0.165
pax6a paired box gene 6a 0.161
sox2 SRY-box containing gene 2 0.160
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.145
wnt3a wingless-type MMTV integration site family, member 3A 0.143
ephb4b eph receptor B4b 0.142
edn1 endothelin 1 0.141
tbx24 T-box 24 0.140
epb4.1l4 erythrocyte protein band 4.1-like 4 0.140
otpb orthopedia homolog b 0.139
otx5 orthodenticle homolog 5 0.131
hoxb2a homeo box B2a 0.130
dld deltaD 0.122
epha4b eph receptor A4b 0.121
hgfa hepatocyte growth factor a 0.119
gpia glucose phosphate isomerase a 0.118
wt1b wilms tumor 1b 0.118
gata5 GATA-binding protein 5 0.118
gata4 GATA-binding protein 4 0.118
dnmt8 DNA (cytosine-5-)-methyltransferase 8 0.118
jag2 jagged 2 0.117
dkk1b dickkopf 1b 0.113
shhb sonic hedgehog b 0.111
irx1b iroquois homeobox protein 1, b 0.110
dbx1b developing brain homeobox 1b 0.098
spry2 sprouty homolog 2 0.096
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.096
pitx3 paired-like homeodomain transcription factor 3 0.094
dlx2a distal-less homeobox gene 2a 0.092
cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b 0.092
pbx1a pre-B-cell leukemia transcription factor 1a 0.092
meis2.1 myeloid ecotropic viral integration site 2.1 0.091
flh floating head 0.088
osr1 odd-skipped related 1 (Drosophila) 0.087
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Hsp90b1 heat shock protein 90, beta, member 1 0.214
Manf mesencephalic astrocyte-derived neurotrophic factor 0.175
Pdia3 protein disulfide isomerase family A, member 3 0.146
Egr1 early growth response 1 0.100
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.071
Pdia6 protein disulfide isomerase family A, member 6 0.056
Dusp6 dual specificity phosphatase 6 0.055
Serp1 stress-associated endoplasmic reticulum protein 1 0.047
Magt1 magnesium transporter 1 0.047
Kcnc3 potassium voltage gated channel, Shaw-related subfamily, member 3 0.044
Canx calnexin 0.038
Gja1 gap junction protein, alpha 1 0.035
Rab1 RAB1, member RAS oncogene family 0.033
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.031
Fos FBJ osteosarcoma oncogene 0.030
Itih4 inter alpha-trypsin inhibitor, heavy chain 4 0.030
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.029
Ccnb1 cyclin B1 0.029
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.028
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.027
Gria1 glutamate receptor, ionotropic, AMPA 1 0.025
Cplx2 complexin 2 0.023
Crhbp corticotropin releasing hormone binding protein 0.023
Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor 0.022
Gulo gulonolactone (L-) oxidase 0.022
Sdf2l1 stromal cell-derived factor 2-like 1 0.022
Uncx UNC homeobox 0.022
Pou6f1 POU class 6 homeobox 1 0.022
Gata3 GATA binding protein 3 0.021
Camk4 calcium/calmodulin-dependent protein kinase IV 0.021
Hpcal4 hippocalcin-like 4 0.021
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 0.021
Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.021
Nos1ap nitric oxide synthase 1 (neuronal) adaptor protein 0.020
Rabac1 Rab acceptor 1 (prenylated) 0.020
Tyms thymidylate synthetase 0.020
Sema3a sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.019
Sncb synuclein, beta 0.019
Racgap1 Rac GTPase-activating protein 1 0.019
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.019
Kalrn kalirin, RhoGEF kinase 0.018
Semg1 semenogelin I 0.018
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 0.018
Creld2 cysteine-rich with EGF-like domains 2 0.018
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.018
Cald1 caldesmon 1 0.018
Zfp382 zinc finger protein 382 0.018
Nppc natriuretic peptide precursor C 0.018
Nusap1 nucleolar and spindle associated protein 1 0.018
Kcnt1 potassium channel, subfamily T, member 1 0.018
Gnrhr gonadotropin releasing hormone receptor 0.018
Ptk7 PTK7 protein tyrosine kinase 7 0.018
Uso1 USO1 homolog, vesicle docking protein (yeast) 0.018
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.017
Lhx5 LIM homeobox 5 0.017
Amh anti-Mullerian hormone 0.017
Olr287 olfactory receptor 287 0.017
Tecr trans-2,3-enoyl-CoA reductase 0.016
Ptafr platelet-activating factor receptor 0.016
Hrh1 histamine receptor H 1 0.016
Btg2 BTG family, member 2 0.016
Gabrp gamma-aminobutyric acid (GABA-A) receptor, pi 0.016
Clcn4-2 chloride channel 4-2 0.016
Prss2 protease, serine, 2 0.016
Atf3 activating transcription factor 3 0.016
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.015
Ndfip2 Nedd4 family interacting protein 2 0.015
Junb jun B proto-oncogene 0.015
Wt1 Wilms tumor 1 0.015
Capn8 calpain 8 0.015
Nrg2 neuregulin 2 0.015
Fgd4 FYVE, RhoGEF and PH domain containing 4 0.015
Gna11 guanine nucleotide binding protein, alpha 11 0.015
Foxc2 forkhead box C2 0.015
Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 0.015
Adarb2 adenosine deaminase, RNA-specific, B2 0.015
Cckbr cholecystokinin B receptor 0.015
Prpg1 proline-rich proteoglycan 1 0.014
Hoxd3 homeo box D3 0.014
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.014
Cyr61 cysteine-rich, angiogenic inducer, 61 0.014
Neurod2 neurogenic differentiation 2 0.014
Gria4 glutamate receptor, ionotrophic, AMPA 4 0.014
Pyy peptide YY (mapped) 0.014
Psgb1 pregnancy-specific beta 1-glycoprotein 0.014
Col9a1 collagen, type IX, alpha 1 0.014
Lin7a lin-7 homolog a (C. elegans) 0.014
Notch3 Notch homolog 3 (Drosophila) 0.014
Thpo thrombopoietin 0.014
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.014
RragB Ras-related GTP binding B 0.014
Aqp4 aquaporin 4 0.013
Plk4 polo-like kinase 4 (Drosophila) 0.013
Prl4a1 prolactin family 4, subfamily a, member 1 0.013
Hoxc4 homeo box C4 0.013
Cldn7 claudin 7 0.013
Matk megakaryocyte-associated tyrosine kinase 0.013
G6pc glucose-6-phosphatase, catalytic subunit 0.013
Sdc2 syndecan 2 0.013
Ugt8 UDP glycosyltransferase 8 0.013
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism