The network for 'positive regulation of exit from mitosis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of exit from mitosis

Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).

Mus musculus
Name Description Probability Func Analog Organism
Neurod4 neurogenic differentiation 4 0.989
Neurod1 neurogenic differentiation 1 0.989
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.975
Otx2 orthodenticle homolog 2 (Drosophila) 0.873
Pax6 paired box gene 6 0.800
Neurog2 neurogenin 2 0.615
Onecut1 one cut domain, family member 1 0.614
Ccnb2 cyclin B2 0.612
Isl1 ISL1 transcription factor, LIM/homeodomain 0.610
Shh sonic hedgehog 0.586
Gnrhr gonadotropin releasing hormone receptor 0.560
Gata1 GATA binding protein 1 0.556
Hand2 heart and neural crest derivatives expressed transcript 2 0.533
Lep leptin 0.510
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.447
Cdk1 cyclin-dependent kinase 1 0.442
Tcf3 transcription factor 3 0.405
Mecom MDS1 and EVI1 complex locus 0.399
Ccnb1 cyclin B1 0.386
Ube2c ubiquitin-conjugating enzyme E2C 0.356
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.339
Cbfa2t3 core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) 0.326
Hoxa1 homeobox A1 0.292
Mki67 antigen identified by monoclonal antibody Ki 67 0.288
Nkx3-2 NK3 homeobox 2 0.285
Rim4 recombination induced mutation 4 0.277
Runx1t1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.259
Neurog3 neurogenin 3 0.253
Ptf1a pancreas specific transcription factor, 1a 0.250
Kiss1 KiSS-1 metastasis-suppressor 0.247
Hoxd13 homeobox D13 0.245
Nhlh1 nescient helix loop helix 1 0.238
Prph2 peripherin 2 0.229
Ccna2 cyclin A2 0.226
Foxc2 forkhead box C2 0.186
Hand1 heart and neural crest derivatives expressed transcript 1 0.178
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.176
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.174
Pdx1 pancreatic and duodenal homeobox 1 0.162
Crb2 crumbs homolog 2 (Drosophila) 0.159
Sox11 SRY-box containing gene 11 0.151
Lhx5 LIM homeobox protein 5 0.140
H2afx H2A histone family, member X 0.133
Tgfbr2 transforming growth factor, beta receptor II 0.132
Trp53 transformation related protein 53 0.116
Prc1 protein regulator of cytokinesis 1 0.115
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.113
Rrm2 ribonucleotide reductase M2 0.113
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.113
Csf1 colony stimulating factor 1 (macrophage) 0.110
Mxd3 Max dimerization protein 3 0.108
En1 engrailed 1 0.107
Plk1 polo-like kinase 1 (Drosophila) 0.105
Gsc goosecoid homeobox 0.104
Aurkb aurora kinase B 0.096
Cdca8 cell division cycle associated 8 0.095
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.092
Dlx6 distal-less homeobox 6 0.089
Kif20a kinesin family member 20A 0.088
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.083
Prph peripherin 0.079
Tlx3 T-cell leukemia, homeobox 3 0.078
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 0.077
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.075
Prrx1 paired related homeobox 1 0.074
Kif22 kinesin family member 22 0.074
Gnrh1 gonadotropin releasing hormone 1 0.073
Gpsm3 G-protein signalling modulator 3 (AGS3-like, C. elegans) 0.073
Tcfap2a transcription factor AP-2, alpha 0.072
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.071
Col1a1 collagen, type I, alpha 1 0.071
Ebf2 early B-cell factor 2 0.068
Snai1 snail homolog 1 (Drosophila) 0.066
Gli2 GLI-Kruppel family member GLI2 0.064
Mip major intrinsic protein of eye lens fiber 0.064
Efna2 ephrin A2 0.064
Cdx2 caudal type homeobox 2 0.063
Tal1 T-cell acute lymphocytic leukemia 1 0.061
Alx3 aristaless-like homeobox 3 0.060
Pax3 paired box gene 3 0.060
Pou3f2 POU domain, class 3, transcription factor 2 0.059
Foxd2 forkhead box D2 0.059
Birc5 baculoviral IAP repeat-containing 5 0.058
Hba-x hemoglobin X, alpha-like embryonic chain in Hba complex 0.058
Meox1 mesenchyme homeobox 1 0.057
Pten phosphatase and tensin homolog 0.056
Tbx1 T-box 1 0.056
Hoxd11 homeobox D11 0.055
E2f1 E2F transcription factor 1 0.054
Notch2 Notch gene homolog 2 (Drosophila) 0.053
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.052
Srrm4 serine/arginine repetitive matrix 4 0.052
Fgf17 fibroblast growth factor 17 0.052
Csf1r colony stimulating factor 1 receptor 0.052
Fes feline sarcoma oncogene 0.050
Hoxd12 homeobox D12 0.050
Racgap1 Rac GTPase-activating protein 1 0.049
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.048
Dok1 docking protein 1 0.047
Hic1 hypermethylated in cancer 1 0.047
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.841
AURKB aurora kinase B 0.804
INCENP inner centromere protein antigens 135/155kDa 0.633
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.363
PLK1 polo-like kinase 1 0.281
CDCA8 cell division cycle associated 8 0.279
PTTG1 pituitary tumor-transforming 1 0.253
TROAP trophinin associated protein (tastin) 0.231
GTSE1 G-2 and S-phase expressed 1 0.145
FAM64A family with sequence similarity 64, member A 0.143
UBE2C ubiquitin-conjugating enzyme E2C 0.137
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.133
ENG endoglin 0.105
CDCA3 cell division cycle associated 3 0.094
BIRC5 baculoviral IAP repeat containing 5 0.080
PSRC1 proline/serine-rich coiled-coil 1 0.064
CCNF cyclin F 0.053
FOXM1 forkhead box M1 0.051
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 0.048
KIF2C kinesin family member 2C 0.044
CENPA centromere protein A 0.043
HJURP Holliday junction recognition protein 0.039
KIF20A kinesin family member 20A 0.038
CDC25C cell division cycle 25 homolog C (S. pombe) 0.035
FSTL1 follistatin-like 1 0.034
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.027
MKI67 antigen identified by monoclonal antibody Ki-67 0.024
MYBL2 v-myb myeloblastosis viral oncogene homolog (avian)-like 2 0.020
TPX2 TPX2, microtubule-associated, homolog (Xenopus laevis) 0.019
KIFC1 kinesin family member C1 0.018
RECQL4 RecQ protein-like 4 0.018
GAS2L3 growth arrest-specific 2 like 3 0.016
TGFBR1 transforming growth factor, beta receptor 1 0.015
UBE2S ubiquitin-conjugating enzyme E2S 0.013
TK1 thymidine kinase 1, soluble 0.013
TACC3 transforming, acidic coiled-coil containing protein 3 0.013
E2F1 E2F transcription factor 1 0.013
KIF18B kinesin family member 18B 0.013
ASF1B ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.013
CDKN3 cyclin-dependent kinase inhibitor 3 0.013
CCNB2 cyclin B2 0.012
CENPM centromere protein M 0.011
H2AFX H2A histone family, member X 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism