The network for 'spinal cord dorsal ventral patterning' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

spinal cord dorsal ventral patterning

The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.

Mus musculus
Name Description Probability Func Analog Organism
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Shh sonic hedgehog 0.999
Pitx2 paired-like homeodomain transcription factor 2 0.997
Pax2 paired box gene 2 0.995
Gli3 GLI-Kruppel family member GLI3 0.990
Rarg retinoic acid receptor, gamma 0.973
Isl1 ISL1 transcription factor, LIM/homeodomain 0.970
Fgf8 fibroblast growth factor 8 0.969
Tcfap2a transcription factor AP-2, alpha 0.964
Pax3 paired box gene 3 0.959
Pax6 paired box gene 6 0.948
Foxc1 forkhead box C1 0.947
Tbx1 T-box 1 0.942
Rarb retinoic acid receptor, beta 0.920
Foxc2 forkhead box C2 0.919
Gli2 GLI-Kruppel family member GLI2 0.915
Msx2 homeobox, msh-like 2 0.884
Lhx1 LIM homeobox protein 1 0.882
Hand2 heart and neural crest derivatives expressed transcript 2 0.873
Emx2 empty spiracles homolog 2 (Drosophila) 0.856
Eya1 eyes absent 1 homolog (Drosophila) 0.847
Smo smoothened homolog (Drosophila) 0.820
Hand1 heart and neural crest derivatives expressed transcript 1 0.817
Lef1 lymphoid enhancer binding factor 1 0.814
Lhx3 LIM homeobox protein 3 0.811
Msx1 homeobox, msh-like 1 0.793
Lmx1b LIM homeobox transcription factor 1 beta 0.773
Fgf10 fibroblast growth factor 10 0.753
Nog noggin 0.748
Sox9 SRY-box containing gene 9 0.744
Bmp7 bone morphogenetic protein 7 0.707
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.699
Lmx1a LIM homeobox transcription factor 1 alpha 0.681
Hoxd3 homeobox D3 0.678
Otx1 orthodenticle homolog 1 (Drosophila) 0.675
Gbx2 gastrulation brain homeobox 2 0.671
Emx1 empty spiracles homolog 1 (Drosophila) 0.654
Insm1 insulinoma-associated 1 0.650
Sox3 SRY-box containing gene 3 0.618
Hoxa3 homeobox A3 0.587
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.526
Gsc goosecoid homeobox 0.487
Fgfr2 fibroblast growth factor receptor 2 0.483
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.464
Hoxd11 homeobox D11 0.437
Dlx5 distal-less homeobox 5 0.431
Nkx6-1 NK6 homeobox 1 0.428
Phox2b paired-like homeobox 2b 0.405
Rara retinoic acid receptor, alpha 0.404
Hoxd13 homeobox D13 0.396
Hoxa1 homeobox A1 0.340
Col2a1 collagen, type II, alpha 1 0.299
Foxg1 forkhead box G1 0.299
Nodal nodal 0.295
Bmp4 bone morphogenetic protein 4 0.288
En1 engrailed 1 0.282
Vax1 ventral anterior homeobox containing gene 1 0.272
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.265
Sox2 SRY-box containing gene 2 0.257
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.239
Hoxb1 homeobox B1 0.228
Nkx3-2 NK3 homeobox 2 0.220
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.210
Cdon cell adhesion molecule-related/down-regulated by oncogenes 0.203
Pax9 paired box gene 9 0.203
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.198
Sox11 SRY-box containing gene 11 0.185
Ret ret proto-oncogene 0.184
Foxp3 forkhead box P3 0.183
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.166
Foxh1 forkhead box H1 0.164
Neurog2 neurogenin 2 0.163
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.159
Lhx4 LIM homeobox protein 4 0.154
Gpr27 G protein-coupled receptor 27 0.147
Hes5 hairy and enhancer of split 5 (Drosophila) 0.146
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.143
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.142
Dlx6 distal-less homeobox 6 0.140
Sall3 sal-like 3 (Drosophila) 0.140
Six2 sine oculis-related homeobox 2 homolog (Drosophila) 0.138
Sct secretin 0.136
Pdx1 pancreatic and duodenal homeobox 1 0.134
Chrd chordin 0.132
Hoxa4 homeobox A4 0.129
Lhx5 LIM homeobox protein 5 0.128
Evx2 even skipped homeotic gene 2 homolog 0.126
Tlx3 T-cell leukemia, homeobox 3 0.125
Hoxb6 homeobox B6 0.124
Setdb1 SET domain, bifurcated 1 0.124
Atoh7 atonal homolog 7 (Drosophila) 0.121
Socs1 suppressor of cytokine signaling 1 0.120
Hoxa5 homeobox A5 0.117
Zic2 zinc finger protein of the cerebellum 2 0.116
Megf8 multiple EGF-like-domains 8 0.116
Neurod1 neurogenic differentiation 1 0.112
Mesp1 mesoderm posterior 1 0.112
Wnt1 wingless-related MMTV integration site 1 0.112
Gdnf glial cell line derived neurotrophic factor 0.110
Pou4f2 POU domain, class 4, transcription factor 2 0.108
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
shha sonic hedgehog a 0.994
dla deltaA 0.842
pax2a paired box gene 2a 0.831
nkx2.2a NK2 transcription factor related 2a 0.734
ptch2 patched 2 0.528
ascl1a achaete-scute complex-like 1a (Drosophila) 0.474
notch1a notch homolog 1a 0.442
gli1 GLI-Kruppel family member 1 0.412
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.363
smo smoothened homolog (Drosophila) 0.316
dbx1a developing brain homeobox 1a 0.310
rerea arginine-glutamic acid dipeptide (RE) repeats a 0.297
neurog1 neurogenin 1 0.296
gli2a GLI-Kruppel family member GLI2a 0.268
isl1 islet1 0.257
fgf8a fibroblast growth factor 8 a 0.148
lef1 lymphocyte enhancer binding factor 1 0.147
hoxb1b homeo box B1b 0.111
dld deltaD 0.092
ascl1b achaete-scute complex-like 1b (Drosophila) 0.083
olig2 oligodendrocyte lineage transcription factor 2 0.074
pax6a paired box gene 6a 0.071
tp53 tumor protein p53 0.068
mib mind bomb 0.068
olig3 oligodendrocyte transcription factor 3 0.068
otpb orthopedia homolog b 0.063
sox10 SRY-box containing gene 10 0.059
dcc deleted in colorectal carcinoma 0.059
neurod neurogenic differentiation 0.058
foxd3 forkhead box D3 0.057
foxa2 forkhead box A2 0.057
ndr2 nodal-related 2 0.056
cdh2 cadherin 2, neuronal 0.054
ptch1 patched 1 0.052
apc adenomatosis polyposis coli 0.051
flh floating head 0.051
tfap2a transcription factor AP-2 alpha 0.051
epb41l5 erythrocyte membrane protein band 4.1 like 5 0.051
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.045
ntla no tail a 0.043
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.041
prkci protein kinase C, iota 0.040
dlb deltaB 0.039
msxc muscle segment homeobox C 0.039
hhip hedgehog interacting protein 0.037
eya1 eyes absent homolog 1 0.036
pnx posterior neuron-specific homeobox 0.035
eng2a engrailed 2a 0.034
fgf3 fibroblast growth factor 3 0.033
notch3 notch homolog 3 0.032
lhx1a LIM homeobox 1a 0.032
sox9a SRY-box containing gene 9a 0.031
gdf6a growth differentiation factor 6a 0.029
neurod4 neurogenic differentiation 4 0.029
sulf1 sulfatase 1 0.029
lhx2b LIM homeobox 2b 0.028
jag1b jagged 1b 0.026
flr fleer 0.025
meis3 myeloid ecotropic viral integration site 3 0.025
insm1b insulinoma-associated 1b 0.024
nkx2.9 NK2 transcription factor related, locus 9 (Drosophila) 0.024
tbx1 T-box 1 0.024
sox3 SRY-box containing gene 3 0.024
vangl2 vang-like 2 (van gogh, Drosophila) 0.024
her8a hairy-related 8a 0.023
gbx1 gastrulation brain homeobox 1 0.023
prdm14 PR domain containing 14 0.023
bmp2b bone morphogenetic protein 2b 0.023
chd chordin 0.022
ext2 exostoses (multiple) 2 0.022
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.022
tbx2b T-box 2b 0.021
foxa1 forkhead box A1 0.020
pcdh18a protocadherin 18a 0.020
sox9b SRY-box containing gene 9b 0.020
fezf2 FEZ family zinc finger 2 0.020
foxg1a forkhead box G1a 0.019
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.019
nr2e3 nuclear receptor subfamily 2, group E, member 3 0.019
otx2 orthodenticle homolog 2 0.018
ptf1a pancreas specific transcription factor, 1a 0.018
epha4b eph receptor A4b 0.018
boc brother of CDO 0.018
ahctf1 AT hook containing transcription factor 1 0.018
pou3f3b POU class 3 homeobox 3b 0.017
atoh7 atonal homolog 7 0.017
cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 0.016
cdx4 caudal type homeo box transcription factor 4 0.016
hoxb2a homeo box B2a 0.016
sulf2 sulfatase 2 0.016
cdh23 cadherin-like 23 0.015
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.015
eng2b engrailed 2b 0.014
sox19a SRY-box containing gene 19a 0.014
lhx5 LIM homeobox 5 0.014
cxcr4b chemokine (C-X-C motif), receptor 4b 0.014
pou3f2 POU class 3 homeobox 2 0.014
hoxd4a homeo box D4a 0.014
foxn4 forkhead box N4 0.013
cc2d2a coiled-coil and C2 domain containing 2A 0.013
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Drosophila melanogaster
Name Description Probability Func Analog Organism
ci cubitus interruptus 0.910
wg wingless 0.858
dpp decapentaplegic 0.851
Egfr Epidermal growth factor receptor 0.840
hh hedgehog 0.840
HLHm7 E(spl) region transcript m7 0.625
ptc patched 0.589
en engrailed 0.403
N Notch 0.308
ara araucan 0.281
amos absent MD neurons and olfactory sensilla 0.269
H Hairless 0.252
ds dachsous 0.187
ato atonal 0.178
eya eyes absent 0.166
E(spl) Enhancer of split 0.145
su(f) suppressor of forked 0.139
18w 18 wheeler 0.134
HLHmgamma E(spl) region transcript mgamma 0.118
pnr pannier 0.118
fng fringe 0.106
brk brinker 0.098
m2 E(spl) region transcript m2 0.096
HLHmbeta E(spl) region transcript mbeta 0.081
m4 E(spl) region transcript m4 0.079
Notum CG13076 gene product from transcript CG13076-RB 0.076
argos CG4531 gene product from transcript CG4531-RA 0.074
sd scalloped 0.073
Rab2 Rab-protein 2 0.068
ecd ecdysoneless 0.066
Hcf Host cell factor 0.061
mam mastermind 0.060
in inturned 0.055
smo smoothened 0.045
oc ocelliless 0.044
CG17273 CG17273 gene product from transcript CG17273-RA 0.044
dally division abnormally delayed 0.043
twi twist 0.043
fz frizzled 0.042
cora coracle 0.039
dac dachshund 0.039
sens senseless 0.038
Mad Mothers against dpp 0.036
hth homothorax 0.036
gbb glass bottom boat 0.035
ac achaete 0.035
noc no ocelli 0.035
G-oalpha47A G protein oalpha 47A 0.035
LIMK1 LIM-kinase1 0.034
rho rhomboid 0.034
cos costa 0.032
HLHm5 E(spl) region transcript m5 0.032
mub mushroom-body expressed 0.029
HLHmdelta E(spl) region transcript mdelta 0.027
Dip1 Dorsal interacting protein 1 0.026
por porcupine 0.026
tan tantalus 0.026
hbs hibris 0.025
Indy I'm not dead yet 0.024
tow target of wingless 0.024
ro rough 0.024
sno strawberry notch 0.023
rpr reaper 0.022
tkv thickveins 0.022
pb proboscipedia 0.022
Gp150 CG5820 gene product from transcript CG5820-RA 0.022
CG34350 CG34350 gene product from transcript CG34350-RA 0.022
dy dusky 0.021
malpha E(spl) region transcript malpha 0.021
tum tumbleweed 0.020
HLHm3 E(spl) region transcript m3 0.020
rempA reduced mechanoreceptor potential A 0.020
CycD Cyclin D 0.020
nkd naked cuticle 0.020
sub subito 0.020
if inflated 0.019
put punt 0.019
sv shaven 0.019
Ubqn Ubiquilin 0.019
dx deltex 0.018
salm spalt major 0.018
myoglianin CG1838 gene product from transcript CG1838-RD 0.018
ase asense 0.017
sll slalom 0.017
fy fuzzy 0.017
kn knot 0.017
sog short gastrulation 0.017
Wnt4 Wnt oncogene analog 4 0.017
dlp dally-like 0.017
Myo31DF Myosin 31DF 0.017
Lmpt Limpet 0.017
kek1 kekkon-1 0.017
cg combgap 0.016
CG8965 CG8965 gene product from transcript CG8965-RA 0.016
Ubx Ultrabithorax 0.016
CG1625 CG1625 gene product from transcript CG1625-RB 0.016
net CG11450 gene product from transcript CG11450-RB 0.015
gro groucho 0.015
krz kurtz 0.015
unc uncoordinated 0.015
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Homo sapiens
Name Description Probability Func Analog Organism
SUFU suppressor of fused homolog (Drosophila) 1.000
GLI1 GLI family zinc finger 1 1.000
NOTCH1 notch 1 1.000
RCN3 reticulocalbin 3, EF-hand calcium binding domain 1.000
NOTCH3 notch 3 1.000
PEX26 peroxisomal biogenesis factor 26 0.998
QPRT quinolinate phosphoribosyltransferase 0.973
MID1IP1 MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish)) 0.967
ZNF764 zinc finger protein 764 0.952
STK36 serine/threonine kinase 36 0.951
NOTCH2 notch 2 0.934
GLIS3 GLIS family zinc finger 3 0.888
ZNF263 zinc finger protein 263 0.765
ATN1 atrophin 1 0.758
VHL von Hippel-Lindau tumor suppressor 0.610
BMP1 bone morphogenetic protein 1 0.431
GFI1B growth factor independent 1B transcription repressor 0.400
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.338
GLI3 GLI family zinc finger 3 0.261
SKI v-ski sarcoma viral oncogene homolog (avian) 0.172
KRTAP4-12 keratin associated protein 4-12 0.158
ZIC1 Zic family member 1 (odd-paired homolog, Drosophila) 0.124
JAG2 jagged 2 0.106
LMX1A LIM homeobox transcription factor 1, alpha 0.078
PDX1 pancreatic and duodenal homeobox 1 0.073
CAV2 caveolin 2 0.070
BAIAP2 BAI1-associated protein 2 0.066
MAML1 mastermind-like 1 (Drosophila) 0.060
EFNB2 ephrin-B2 0.060
BHLHE23 basic helix-loop-helix family, member e23 0.056
JAG1 jagged 1 0.056
TCF4 transcription factor 4 0.051
FBLN1 fibulin 1 0.051
NEUROD1 neurogenic differentiation 1 0.050
LHX2 LIM homeobox 2 0.047
HRG histidine-rich glycoprotein 0.045
HEY1 hairy/enhancer-of-split related with YRPW motif 1 0.044
LTBP4 latent transforming growth factor beta binding protein 4 0.042
LBX1 ladybird homeobox 1 0.036
AGRN agrin 0.035
TRIP6 thyroid hormone receptor interactor 6 0.034
MEGF11 multiple EGF-like-domains 11 0.033
HOXD12 homeobox D12 0.033
XIAP X-linked inhibitor of apoptosis 0.032
GLI2 GLI family zinc finger 2 0.032
EGFL7 EGF-like-domain, multiple 7 0.031
ADAM17 ADAM metallopeptidase domain 17 0.030
LTBP1 latent transforming growth factor beta binding protein 1 0.030
NELL2 NEL-like 2 (chicken) 0.030
EXOC3L2 exocyst complex component 3-like 2 0.030
ISL1 ISL LIM homeobox 1 0.027
ZIC2 Zic family member 2 (odd-paired homolog, Drosophila) 0.025
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.025
DLL4 delta-like 4 (Drosophila) 0.025
TP73 tumor protein p73 0.024
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.023
RAD54L2 RAD54-like 2 (S. cerevisiae) 0.022
DRD2 dopamine receptor D2 0.022
FGF3 fibroblast growth factor 3 0.022
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.022
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.022
LAMA5 laminin, alpha 5 0.022
SOX2 SRY (sex determining region Y)-box 2 0.022
DLL3 delta-like 3 (Drosophila) 0.021
SIX3 SIX homeobox 3 0.021
WNT10A wingless-type MMTV integration site family, member 10A 0.021
EPAS1 endothelial PAS domain protein 1 0.021
MEGF6 multiple EGF-like-domains 6 0.021
NELL1 NEL-like 1 (chicken) 0.021
MXRA5 matrix-remodelling associated 5 0.021
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.021
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.021
PYY peptide YY 0.021
MNX1 motor neuron and pancreas homeobox 1 0.021
VAX2 ventral anterior homeobox 2 0.020
HOXC11 homeobox C11 0.020
IPO13 importin 13 0.020
FEV FEV (ETS oncogene family) 0.020
GIGYF1 GRB10 interacting GYF protein 1 0.020
USHBP1 Usher syndrome 1C binding protein 1 0.020
HEG1 HEG homolog 1 (zebrafish) 0.019
PAM peptidylglycine alpha-amidating monooxygenase 0.019
MSX1 msh homeobox 1 0.019
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.019
SOX1 SRY (sex determining region Y)-box 1 0.019
ADAMTSL4 ADAMTS-like 4 0.018
HES5 hairy and enhancer of split 5 (Drosophila) 0.018
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.018
HOXC8 homeobox C8 0.018
NKX2-2 NK2 homeobox 2 0.018
AMN amnionless homolog (mouse) 0.018
TAL1 T-cell acute lymphocytic leukemia 1 0.017
FGF4 fibroblast growth factor 4 0.017
HOXB13 homeobox B13 0.017
RUNDC3A RUN domain containing 3A 0.017
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.017
PAX6 paired box 6 0.017
POU3F1 POU class 3 homeobox 1 0.017
FIBCD1 fibrinogen C domain containing 1 0.017
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 0.017
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Rattus norvegicus
Name Description Probability Func Analog Organism
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.033
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism