IMP
Process View
The network for 'embryonic heart tube formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
embryonic heart tube formation
The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 1.000 | |
| Msx1 | homeobox, msh-like 1 | 1.000 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 1.000 | |
| Foxc2 | forkhead box C2 | 1.000 | |
| Tcfap2a | transcription factor AP-2, alpha | 1.000 | |
| Pax3 | paired box gene 3 | 1.000 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 1.000 | |
| Prrx1 | paired related homeobox 1 | 1.000 | |
| Pax6 | paired box gene 6 | 1.000 | |
| Fgf8 | fibroblast growth factor 8 | 0.999 | |
| Neurod1 | neurogenic differentiation 1 | 0.999 | |
| Foxc1 | forkhead box C1 | 0.999 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.999 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.999 | |
| Tbx1 | T-box 1 | 0.998 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.998 | |
| Bmp4 | bone morphogenetic protein 4 | 0.998 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.998 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.998 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.997 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.997 | |
| Dlx5 | distal-less homeobox 5 | 0.996 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.996 | |
| Sox9 | SRY-box containing gene 9 | 0.995 | |
| Hoxa1 | homeobox A1 | 0.994 | |
| Smo | smoothened homolog (Drosophila) | 0.994 | |
| Prrx2 | paired related homeobox 2 | 0.993 | |
| Gsc | goosecoid homeobox | 0.992 | |
| Foxg1 | forkhead box G1 | 0.987 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.981 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.980 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.978 | |
| Ednra | endothelin receptor type A | 0.972 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.971 | |
| Neurod4 | neurogenic differentiation 4 | 0.969 | |
| Bmp7 | bone morphogenetic protein 7 | 0.969 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.959 | |
| Chrd | chordin | 0.958 | |
| Msx2 | homeobox, msh-like 2 | 0.958 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.943 | |
| Gata4 | GATA binding protein 4 | 0.939 | |
| Neurog2 | neurogenin 2 | 0.935 | |
| Pax9 | paired box gene 9 | 0.919 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.916 | |
| Nkx3-2 | NK3 homeobox 2 | 0.907 | |
| Dlx2 | distal-less homeobox 2 | 0.903 | |
| Runx2 | runt related transcription factor 2 | 0.891 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.891 | |
| Neurog3 | neurogenin 3 | 0.844 | |
| En1 | engrailed 1 | 0.833 | |
| Sox11 | SRY-box containing gene 11 | 0.807 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.804 | |
| Hoxd3 | homeobox D3 | 0.759 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.755 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.752 | |
| Mecom | MDS1 and EVI1 complex locus | 0.751 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.746 | |
| Pax2 | paired box gene 2 | 0.703 | |
| Alx3 | aristaless-like homeobox 3 | 0.700 | |
| Hoxd13 | homeobox D13 | 0.694 | |
| Hoxa2 | homeobox A2 | 0.646 | |
| Onecut1 | one cut domain, family member 1 | 0.640 | |
| Hoxa3 | homeobox A3 | 0.623 | |
| Lhx3 | LIM homeobox protein 3 | 0.605 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.605 | |
| Dlx6 | distal-less homeobox 6 | 0.603 | |
| Bmp2 | bone morphogenetic protein 2 | 0.599 | |
| Nhlh1 | nescient helix loop helix 1 | 0.586 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.571 | |
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.559 | |
| Sox2 | SRY-box containing gene 2 | 0.554 | |
| Mesp1 | mesoderm posterior 1 | 0.549 | |
| Rarb | retinoic acid receptor, beta | 0.543 | |
| Ntf3 | neurotrophin 3 | 0.519 | |
| Rarg | retinoic acid receptor, gamma | 0.518 | |
| Lhx5 | LIM homeobox protein 5 | 0.508 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.506 | |
| Alx4 | aristaless-like homeobox 4 | 0.500 | |
| T | brachyury | 0.487 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.465 | |
| Hoxd11 | homeobox D11 | 0.462 | |
| Gata1 | GATA binding protein 1 | 0.434 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.433 | |
| Myf5 | myogenic factor 5 | 0.432 | |
| Meox2 | mesenchyme homeobox 2 | 0.429 | |
| Hoxb1 | homeobox B1 | 0.406 | |
| Gpr50 | G-protein-coupled receptor 50 | 0.404 | |
| Fgf10 | fibroblast growth factor 10 | 0.401 | |
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.389 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.377 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.365 | |
| Hoxa10 | homeobox A10 | 0.358 | |
| Insm1 | insulinoma-associated 1 | 0.327 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.312 | |
| Fgf15 | fibroblast growth factor 15 | 0.309 | |
| Lhx9 | LIM homeobox protein 9 | 0.307 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.290 | |
| Foxd2 | forkhead box D2 | 0.278 | |
| Twist1 | twist homolog 1 (Drosophila) | 0.271 |
Loading network...
Danio rerio
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| pax2a | paired box gene 2a | 0.880 | |
| ptf1a | pancreas specific transcription factor, 1a | 0.831 | |
| isl1 | islet1 | 0.602 | |
| atoh1a | atonal homolog 1a | 0.587 | |
| tbx5a | T-box 5a | 0.502 | |
| neurod | neurogenic differentiation | 0.385 | |
| gata1a | GATA binding protein 1a | 0.347 | |
| dla | deltaA | 0.299 | |
| ascl1a | achaete-scute complex-like 1a (Drosophila) | 0.271 | |
| dct | dopachrome tautomerase | 0.256 | |
| evx1 | even-skipped homeobox 1 | 0.240 | |
| hbbe3 | hemoglobin beta embryonic-3 | 0.222 | |
| runx1 | runt-related transcription factor 1 | 0.196 | |
| fli1a | friend leukemia integration 1a | 0.179 | |
| atoh1b | atonal homolog 1b | 0.175 | |
| barhl2 | BarH-like 2 | 0.174 | |
| kdrl | kinase insert domain receptor like | 0.154 | |
| lmo2 | LIM domain only 2 (rhombotin-like 1) | 0.150 | |
| twist1b | twist1b | 0.148 | |
| gdf6a | growth differentiation factor 6a | 0.127 | |
| rx2 | retinal homeobox gene 2 | 0.116 | |
| hhex | hematopoietically expressed homeobox | 0.113 | |
| etv2 | ets variant gene 2 | 0.108 | |
| msxc | muscle segment homeobox C | 0.104 | |
| boc | brother of CDO | 0.104 | |
| foxn4 | forkhead box N4 | 0.099 | |
| col2a1a | collagen type II, alpha-1a | 0.098 | |
| tbx1 | T-box 1 | 0.098 | |
| ptch1 | patched 1 | 0.096 | |
| slc17a7 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 | 0.087 | |
| hoxa2b | homeo box A2b | 0.084 | |
| alcama | activated leukocyte cell adhesion molecule a | 0.084 | |
| eng2a | engrailed 2a | 0.082 | |
| pax6b | paired box gene 6b | 0.081 | |
| lmx1b.1 | LIM homeobox transcription factor 1, beta 1 | 0.076 | |
| cmyb | transcription factor cmyb | 0.073 | |
| mab21l2 | mab-21-like 2 | 0.073 | |
| nkx2.2a | NK2 transcription factor related 2a | 0.072 | |
| fgf10a | fibroblast growth factor 10a | 0.070 | |
| notch1a | notch homolog 1a | 0.070 | |
| hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.069 | |
| nkx3.2 | NK3 homeobox 2 | 0.067 | |
| dlx2a | distal-less homeobox gene 2a | 0.065 | |
| irx1a | iroquois homeobox protein 1, a | 0.064 | |
| mitfa | microphthalmia-associated transcription factor a | 0.063 | |
| znfl2a | zinc finger-like gene 2a | 0.059 | |
| sox9a | SRY-box containing gene 9a | 0.058 | |
| prox1 | prospero-related homeobox gene 1 | 0.058 | |
| myod1 | myogenic differentiation 1 | 0.058 | |
| lhx2b | LIM homeobox 2b | 0.056 | |
| rx1 | retinal homeobox gene 1 | 0.056 | |
| atoh1c | atonal homolog 1c | 0.055 | |
| fgf8a | fibroblast growth factor 8 a | 0.055 | |
| sox10 | SRY-box containing gene 10 | 0.054 | |
| myl7 | myosin, light polypeptide 7, regulatory | 0.052 | |
| dbx1b | developing brain homeobox 1b | 0.050 | |
| vsx2 | visual system homeobox 2 | 0.050 | |
| hoxb5b | homeo box B5b | 0.050 | |
| lhx1b | LIM homeobox 1b | 0.050 | |
| foxa1 | forkhead box A1 | 0.045 | |
| ikzf1 | IKAROS family zinc finger 1 (Ikaros) | 0.042 | |
| pax6a | paired box gene 6a | 0.042 | |
| nkx2.5 | NK2 transcription factor related 5 | 0.041 | |
| hoxc4a | homeo box C4a | 0.041 | |
| hoxb4a | homeo box B4a | 0.040 | |
| tbx2b | T-box 2b | 0.039 | |
| dlc | deltaC | 0.039 | |
| nkx2.1a | NK2 homeobox 1a | 0.038 | |
| otx5 | orthodenticle homolog 5 | 0.034 | |
| tbx18 | T-box 18 | 0.034 | |
| ascl1b | achaete-scute complex-like 1b (Drosophila) | 0.034 | |
| hoxd4a | homeo box D4a | 0.034 | |
| six2a | sine oculis-related homeobox 2a | 0.033 | |
| hoxd11a | homeo box D11a | 0.032 | |
| insm1b | insulinoma-associated 1b | 0.031 | |
| fgf8b | fibroblast growth factor 8 b | 0.031 | |
| foxa2 | forkhead box A2 | 0.031 | |
| eng2b | engrailed 2b | 0.030 | |
| irx4b | iroquois homeobox protein 4b | 0.029 | |
| smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.029 | |
| dmrt3a | doublesex and mab-3 related transcription factor 3a | 0.029 | |
| aldh1a2 | aldehyde dehydrogenase 1 family, member A2 | 0.028 | |
| meis3 | myeloid ecotropic viral integration site 3 | 0.028 | |
| bmp2a | bone morphogenetic protein 2a | 0.027 | |
| gabra1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 0.027 | |
| jag1b | jagged 1b | 0.027 | |
| gdnf | glial cell derived neurotrophic factor | 0.026 | |
| gbx2 | gastrulation brain homeo box 2 | 0.026 | |
| bmper | BMP binding endothelial regulator | 0.026 | |
| dlx3b | distal-less homeobox gene 3b | 0.026 | |
| nkx2.7 | NK2 transcription factor related 7 | 0.026 | |
| hlxb9la | homeo box HB9 like a | 0.026 | |
| hoxa9a | homeo box A9a | 0.026 | |
| chga | chromogranin A | 0.025 | |
| sox9b | SRY-box containing gene 9b | 0.025 | |
| shhb | sonic hedgehog b | 0.025 | |
| dld | deltaD | 0.025 | |
| barhl1.2 | BarH-like 1.2 | 0.025 | |
| crb2a | crumbs homolog 2a | 0.024 | |
| hoxa13b | homeo box A13b | 0.023 |