The network for 'positive regulation of metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

Name Description Probability Func Analog Organism
notch1a notch homolog 1a 0.997
gata3 GATA-binding protein 3 0.987
tp53 tumor protein p53 0.985
her6 hairy-related 6 0.969
tal1 T-cell acute lymphocytic leukemia 1 0.939
dlx5a distal-less homeobox gene 5a 0.920
spry4 sprouty (Drosophila) homolog 4 0.907
shha sonic hedgehog a 0.900
kdrl kinase insert domain receptor like 0.885
nanos3 nanos homolog 3 0.883
pitx2 paired-like homeodomain transcription factor 2 0.878
dlx2a distal-less homeobox gene 2a 0.870
hoxb1b homeo box B1b 0.863
pax8 paired box gene 8 0.842
pax7a paired box gene 7a 0.835
col2a1a collagen type II, alpha-1a 0.824
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.803
pitx3 paired-like homeodomain transcription factor 3 0.801
gli1 GLI-Kruppel family member 1 0.800
runx2b runt-related transcription factor 2b 0.795
tbx5a T-box 5a 0.782
ihha Indian hedgehog homolog a 0.782
myf5 myogenic factor 5 0.780
klf4 Kruppel-like factor 4 0.775
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.772
ascl1a achaete-scute complex-like 1a (Drosophila) 0.763
fn1 fibronectin 1 0.760
evx1 even-skipped homeobox 1 0.726
fezf2 FEZ family zinc finger 2 0.697
sox1a SRY-box containing gene 1a 0.693
foxi1 forkhead box I1 0.675
myod1 myogenic differentiation 1 0.662
foxp2 forkhead box P2 0.660
gata5 GATA-binding protein 5 0.656
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.647
sox9b SRY-box containing gene 9b 0.646
rag1 recombination activating gene 1 0.645
desma desmin a 0.644
otpa orthopedia homolog a 0.637
chd chordin 0.628
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.623
notch3 notch homolog 3 0.622
bmp4 bone morphogenetic protein 4 0.618
six4b sine oculis homeobox homolog 4b 0.595
dlc deltaC 0.578
lhx1a LIM homeobox 1a 0.577
epor erythropoietin receptor 0.570
tgfb3 transforming growth factor, beta 3 0.560
prl prolactin 0.551
sox10 SRY-box containing gene 10 0.550
egr2b early growth response 2b 0.543
eng2a engrailed 2a 0.541
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.539
runx2a runt-related transcription factor 2a 0.535
opn1lw1 opsin 1 (cone pigments), long-wave-sensitive, 1 0.531
irx4b iroquois homeobox protein 4b 0.523
nkx2.5 NK2 transcription factor related 5 0.521
nr2e3 nuclear receptor subfamily 2, group E, member 3 0.519
wnt8b wingless-type MMTV integration site family, member 8b 0.508
fgf17 fibroblast growth factor 17 0.505
mib mind bomb 0.496
ndr2 nodal-related 2 0.493
gata4 GATA-binding protein 4 0.481
nrg2a neuregulin 2a 0.476
tfap2a transcription factor AP-2 alpha 0.476
cmyb transcription factor cmyb 0.473
pkd2 polycystic kidney disease 2 0.472
ca8 carbonic anhydrase VIII 0.471
pcna proliferating cell nuclear antigen 0.468
mapk1 mitogen-activated protein kinase 1 0.450
lhx5 LIM homeobox 5 0.449
wu:fv91b12 wu:fv91b12 0.448
foxa2 forkhead box A2 0.441
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.434
foxn4 forkhead box N4 0.433
sall4 sal-like 4 (Drosophila) 0.428
jun jun proto-oncogene 0.426
sox9a SRY-box containing gene 9a 0.422
fzd7a frizzled homolog 7a 0.421
mab21l2 mab-21-like 2 0.412
scd stearoyl-CoA desaturase (delta-9-desaturase) 0.409
nkx2.2a NK2 transcription factor related 2a 0.405
hoxd10a homeo box D10a 0.395
pax2a paired box gene 2a 0.394
vcana versican a 0.393
emx2 empty spiracles homeobox 2 0.391
nkx2.2b NK2 transcription factor related 2b 0.390
crabp2a cellular retinoic acid binding protein 2, a 0.389
mstnb myostatin b 0.387
bmp2b bone morphogenetic protein 2b 0.387
atoh1a atonal homolog 1a 0.386
hhex hematopoietically expressed homeobox 0.385
otx1b orthodenticle homolog 1b 0.383
gata2a GATA-binding protein 2a 0.373
irx7 iroquois homeobox protein 7 0.372
sall1a sal-like 1a (Drosophila) 0.371
khdrbs1a KH domain containing, RNA binding, signal transduction associated 1a 0.369
gli2a GLI-Kruppel family member GLI2a 0.368
phox2a paired-like homeobox 2a 0.366
atoh1b atonal homolog 1b 0.364
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.997
pha-4 Protein PHA-4 0.995
vab-3 Protein VAB-3 0.957
elt-6 Protein ELT-6 0.907
unc-62 Protein UNC-62 0.823
mat-3 Protein MAT-3 0.778
nhr-67 Protein NHR-67 0.753
ceh-20 Protein CEH-20 0.752
bar-1 Protein BAR-1 0.728
mep-1 Protein MEP-1 0.707
F28C1.1 Protein F28C1.1 0.671
fkh-2 Protein FKH-2 0.655
pry-1 Protein PRY-1 0.652
cam-1 Protein CAM-1 0.611
sel-10 Protein SEL-10 0.610
daf-3 Protein DAF-3 0.593
his-31 Protein HIS-31 0.593
F39B2.1 Protein F39B2.1 0.590
lag-1 Protein LAG-1 0.587
pop-1 Protein POP-1 0.580
pgl-1 Protein PGL-1 0.575
egl-44 Protein EGL-44 0.553
sas-4 Protein SAS-4 0.548
odr-3 Protein ODR-3 0.543
attf-2 Protein ATTF-2 0.532
unc-42 Protein UNC-42 0.530
lin-36 Protein LIN-36 0.526
nhr-49 Protein NHR-49 0.526
atg-2 Protein ATG-2 0.525
zip-7 Protein ZIP-7 0.522
glp-1 Protein GLP-1 0.521
F53F10.2 Protein F53F10.2 0.516
ant-1.1 Protein ANT-1.1 0.514
lin-48 Protein LIN-48 0.509
htz-1 Protein HTZ-1 0.507
egl-46 Protein EGL-46 0.502
hsr-9 Protein HSR-9 0.496
daf-11 Protein DAF-11 0.483
ceh-21 Protein CEH-21 0.483
sli-1 Protein SLI-1 0.480
hlh-1 Protein HLH-1 0.478
his-1 Protein HIS-1 0.473
CELE_C17E4.6 Protein C17E4.6 0.469
mcm-7 Protein MCM-7 0.468
cnd-1 Protein CND-1 0.457
ced-9 Protein CED-9 0.454
T28F4.1 Protein T28F4.1 0.453
zyg-9 Protein ZYG-9 0.453
unc-73 Protein UNC-73 0.438
his-64 Protein HIS-64 0.430
F41C3.4 Protein F41C3.4 0.413
R11A8.7 Protein R11A8.7 0.409
CELE_W03F9.10 Protein W03F9.10 0.408
hmg-1.2 Protein HMG-1.2 0.407
rgs-7 Protein RGS-7 0.405
CELE_F47G4.4 Protein F47G4.4 0.402
unc-40 Protein UNC-40 0.399
F28B3.1 Protein F28B3.1 0.391
rps-2 Protein RPS-2 0.390
dnj-12 Protein DNJ-12 0.387
pbrm-1 Protein PBRM-1 0.386
ajm-1 Protein AJM-1 0.382
unc-43 Protein UNC-43 0.377
unc-84 Protein UNC-84 0.374
syx-4 Protein SYX-4 0.369
nhr-45 Protein NHR-45 0.365
rad-26 Protein RAD-26 0.361
daf-14 Protein DAF-14 0.360
tol-1 Protein TOL-1 0.359
his-5 Protein HIS-5 0.358
unc-37 Protein UNC-37 0.355
hlh-2 Protein HLH-2 0.352
cdk-1 Protein CDK-1 0.350
frm-7 Protein FRM-7 0.348
npp-16 Protein NPP-16 0.343
saeg-1 Protein SAEG-1 0.341
alg-2 Protein ALG-2 0.340
nhr-6 Protein NHR-6 0.339
lin-17 Protein LIN-17 0.330
lin-1 Protein LIN-1 0.326
wwp-1 Protein WWP-1 0.326
zfp-3 Protein ZFP-3 0.323
egl-13 Protein EGL-13 0.322
msp-78 Protein MSP-78 0.318
eri-1 Protein ERI-1 0.317
set-1 Protein SET-1 0.317
unc-14 Protein UNC-14 0.316
icd-1 Protein ICD-1 0.315
csr-1 Protein CSR-1 0.313
K10D6.4 Protein K10D6.4 0.311
atn-1 Protein ATN-1 0.311
daf-1 Protein DAF-1 0.307
hbl-1 Protein HBL-1 0.306
lsy-2 Protein LSY-2 0.301
ztf-2 Protein ZTF-2 0.297
rab-5 Protein RAB-5 0.297
mig-5 Protein MIG-5 0.295
CELE_Y106G6D.7 Protein Y106G6D.7 0.295
C27A12.7 Protein C27A12.7 0.291
msp-50 Protein MSP-50 0.291
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism