IMP

Process View

Homo sapiens

23 genes annotated in human

regulation of lipid catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of lipid catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of lipid catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
APOA1	apolipoprotein A-I	1.000	Human
ALB	albumin	0.997
INSR	insulin receptor	0.992
IL1R1	interleukin 1 receptor, type I	0.990
FGA	fibrinogen alpha chain	0.980
APOE	apolipoprotein E	0.972
CDK2	cyclin-dependent kinase 2	0.959	Yeast
HP	haptoglobin	0.942
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.930
GRB10	growth factor receptor-bound protein 10	0.897
APOC3	apolipoprotein C-III	0.893
MPDZ	multiple PDZ domain protein	0.744
NCF1	neutrophil cytosolic factor 1	0.718
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.705
NOXA1	NADPH oxidase activator 1	0.646
IGF1R	insulin-like growth factor 1 receptor	0.634
APOA2	apolipoprotein A-II	0.572
PEX19	peroxisomal biogenesis factor 19	0.510
CRP	C-reactive protein, pentraxin-related	0.471
IL1R2	interleukin 1 receptor, type II	0.462
LCAT	lecithin-cholesterol acyltransferase	0.415
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.375
CDCP1	CUB domain containing protein 1	0.370
SETD8	SET domain containing (lysine methyltransferase) 8	0.336
LRP1	low density lipoprotein receptor-related protein 1	0.309
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.287
FGB	fibrinogen beta chain	0.280
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.257
IL1RAP	interleukin 1 receptor accessory protein	0.252
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.243
CCNE1	cyclin E1	0.242
PRKCA	protein kinase C, alpha	0.223
APOA4	apolipoprotein A-IV	0.211
MAPT	microtubule-associated protein tau	0.204
ETFB	electron-transfer-flavoprotein, beta polypeptide	0.193
SH3RF1	SH3 domain containing ring finger 1	0.190
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.181
RUNX1	runt-related transcription factor 1	0.180
APOB	apolipoprotein B (including Ag(x) antigen)	0.173
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.171
CCL14	chemokine (C-C motif) ligand 14	0.170
TRADD	TNFRSF1A-associated via death domain	0.159
GATA2	GATA binding protein 2	0.158
ARRDC3	arrestin domain containing 3	0.156
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.154
APOC1	apolipoprotein C-I	0.150
ACACA	acetyl-CoA carboxylase alpha	0.140
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.133
KAT2B	K(lysine) acetyltransferase 2B	0.132
IRS1	insulin receptor substrate 1	0.132
ADORA2A	adenosine A2a receptor	0.121
CREBBP	CREB binding protein	0.120
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.119
AHSG	alpha-2-HS-glycoprotein	0.118
F2	coagulation factor II (thrombin)	0.116
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.114
RARA	retinoic acid receptor, alpha	0.103
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.095
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.087
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.085
DEPTOR	DEP domain containing MTOR-interacting protein	0.083
TTR	transthyretin	0.079
PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	0.076
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.073
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.073
RPTOR	regulatory associated protein of MTOR, complex 1	0.071
APOC2	apolipoprotein C-II	0.067
ITGB5	integrin, beta 5	0.064
PCSK9	proprotein convertase subtilisin/kexin type 9	0.064
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.064
TAL1	T-cell acute lymphocytic leukemia 1	0.062	Human
GATA4	GATA binding protein 4	0.058
AKT1S1	AKT1 substrate 1 (proline-rich)	0.057
RICTOR	RPTOR independent companion of MTOR, complex 2	0.057
SKP2	S-phase kinase-associated protein 2 (p45)	0.056
PRKCZ	protein kinase C, zeta	0.056	Human
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.056
STAT5B	signal transducer and activator of transcription 5B	0.052
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.050
PTEN	phosphatase and tensin homolog	0.042
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.042
LIPE	lipase, hormone-sensitive	0.041
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.041
PEX3	peroxisomal biogenesis factor 3	0.040
CCL20	chemokine (C-C motif) ligand 20	0.038
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.038
ABCD1	ATP-binding cassette, sub-family D (ALD), member 1	0.038	Human
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.038
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.037
MED1	mediator complex subunit 1	0.037
CCNB2	cyclin B2	0.037
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.037	Human
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.036
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.036
PEX14	peroxisomal biogenesis factor 14	0.036
PDX1	pancreatic and duodenal homeobox 1	0.034
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.033
FOXO3	forkhead box O3	0.033
IRS2	insulin receptor substrate 2	0.032
TCF12	transcription factor 12	0.032
PGRMC1	progesterone receptor membrane component 1	0.032
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.032
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.031
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.031
FAM83C	family with sequence similarity 83, member C	0.030
PXMP2	peroxisomal membrane protein 2, 22kDa	0.030
HTR6	5-hydroxytryptamine (serotonin) receptor 6	0.030
PICK1	protein interacting with PRKCA 1	0.030
NCOA6	nuclear receptor coactivator 6	0.028
E2F1	E2F transcription factor 1	0.028
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.027
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.027
SAMD4B	sterile alpha motif domain containing 4B	0.027
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.027
TBC1D10A	TBC1 domain family, member 10A	0.027
PEX11B	peroxisomal biogenesis factor 11 beta	0.026
SESN2	sestrin 2	0.026
F7	coagulation factor VII (serum prothrombin conversion accelerator)	0.025
SPRR2A	small proline-rich protein 2A	0.025
SSTR3	somatostatin receptor 3	0.024
PEX16	peroxisomal biogenesis factor 16	0.024
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.023
TBR1	T-box, brain, 1	0.023
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.023
PLIN4	perilipin 4	0.023
POU4F3	POU class 4 homeobox 3	0.022
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	0.022
MYOD1	myogenic differentiation 1	0.021
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.021	Human
PHOX2A	paired-like homeobox 2a	0.021
EZR	ezrin	0.021
FOXO1	forkhead box O1	0.021
POU4F2	POU class 4 homeobox 2	0.021
AVPR1A	arginine vasopressin receptor 1A	0.020
SORBS2	sorbin and SH3 domain containing 2	0.020
DDA1	DET1 and DDB1 associated 1	0.020
TRIM9	tripartite motif containing 9	0.020
CCHCR1	coiled-coil alpha-helical rod protein 1	0.019
TSC22D1	TSC22 domain family, member 1	0.019
PEX13	peroxisomal biogenesis factor 13	0.019
ZNF71	zinc finger protein 71	0.019
AGXT	alanine-glyoxylate aminotransferase	0.019
PRKCB	protein kinase C, beta	0.019
NR1D1	nuclear receptor subfamily 1, group D, member 1	0.019
ASGR2	asialoglycoprotein receptor 2	0.019
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.018
PTPLB	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b	0.018
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.018
HAND2	heart and neural crest derivatives expressed 2	0.018	Human
PLCG1	phospholipase C, gamma 1	0.018
PTPRB	protein tyrosine phosphatase, receptor type, B	0.018
P2RY1	purinergic receptor P2Y, G-protein coupled, 1	0.018
MBD1	methyl-CpG binding domain protein 1	0.017
STK4	serine/threonine kinase 4	0.017
CIDEA	cell death-inducing DFFA-like effector a	0.017
POFUT1	protein O-fucosyltransferase 1	0.017
TSHR	thyroid stimulating hormone receptor	0.017
HOXD12	homeobox D12	0.017
LHX5	LIM homeobox 5	0.017
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.017
NEUROG1	neurogenin 1	0.017	Human
AMN	amnionless homolog (mouse)	0.017
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.017
CCNA2	cyclin A2	0.017
KRT1	keratin 1	0.017
FOXF2	forkhead box F2	0.016
PDPK1	3-phosphoinositide dependent protein kinase-1	0.016
FMR1	fragile X mental retardation 1	0.016
SLC35A3	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3	0.016
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.016
TNIP2	TNFAIP3 interacting protein 2	0.016
SOX1	SRY (sex determining region Y)-box 1	0.016
KRT9	keratin 9	0.016
HIST1H1A	histone cluster 1, H1a	0.016
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.016
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.016	Rat
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.016
KISS1	KiSS-1 metastasis-suppressor	0.016
WNT11	wingless-type MMTV integration site family, member 11	0.016
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.016
SNX27	sorting nexin family member 27	0.015
GRM7	glutamate receptor, metabotropic 7	0.015
MAPKAP1	mitogen-activated protein kinase associated protein 1	0.015
ALDOB	aldolase B, fructose-bisphosphate	0.015
AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	0.015
POU3F4	POU class 3 homeobox 4	0.015
UCP1	uncoupling protein 1 (mitochondrial, proton carrier)	0.015
CLEC4G	C-type lectin domain family 4, member G	0.015
PRR5	proline rich 5 (renal)	0.015
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.015	Mouse
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.015
RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	0.014
APCS	amyloid P component, serum	0.014
RETN	resistin	0.014
LMO2	LIM domain only 2 (rhombotin-like 1)	0.014
CACNG3	calcium channel, voltage-dependent, gamma subunit 3	0.014
AGPAT2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.014
IRAK2	interleukin-1 receptor-associated kinase 2	0.013
DRD2	dopamine receptor D2	0.013
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.013
CYBA	cytochrome b-245, alpha polypeptide	0.013
HPX	hemopexin	0.013
P2RX3	purinergic receptor P2X, ligand-gated ion channel, 3	0.013
SCARB1	scavenger receptor class B, member 1	0.013	Mouse
TTC3	tetratricopeptide repeat domain 3	0.013
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.013
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.013
HTR1E	5-hydroxytryptamine (serotonin) receptor 1E	0.013	Human
GPR109B	G protein-coupled receptor 109B	0.013
HTR5A	5-hydroxytryptamine (serotonin) receptor 5A	0.013	Human
GLI1	GLI family zinc finger 1	0.013
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.013
FABP2	fatty acid binding protein 2, intestinal	0.013
HAO2	hydroxyacid oxidase 2 (long chain)	0.013
TRIM15	tripartite motif containing 15	0.013
GABRB1	gamma-aminobutyric acid (GABA) A receptor, beta 1	0.013
FTCD	formiminotransferase cyclodeaminase	0.013
MLXIPL	MLX interacting protein-like	0.012
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.012
ZFPM1	zinc finger protein, multitype 1	0.012
ALPPL2	alkaline phosphatase, placental-like 2	0.012
HAMP	hepcidin antimicrobial peptide	0.012
DCTN1	dynactin 1	0.012
DSCAML1	Down syndrome cell adhesion molecule like 1	0.012
FGF3	fibroblast growth factor 3	0.012
LBP	lipopolysaccharide binding protein	0.012
CKS2	CDC28 protein kinase regulatory subunit 2	0.012
LMX1A	LIM homeobox transcription factor 1, alpha	0.012
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.012
ARG1	arginase, liver	0.012
PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	0.012
FOXJ1	forkhead box J1	0.012
APOC4	apolipoprotein C-IV	0.012
GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	0.012
CDX2	caudal type homeobox 2	0.012
LRRN2	leucine rich repeat neuronal 2	0.012
MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	0.012
PNPLA3	patatin-like phospholipase domain containing 3	0.012	Human
CSK	c-src tyrosine kinase	0.012
SFRP5	secreted frizzled-related protein 5	0.011
PRLHR	prolactin releasing hormone receptor	0.011
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.011
SLC38A3	solute carrier family 38, member 3	0.011
INS	insulin	0.011
TICAM2	toll-like receptor adaptor molecule 2	0.011
FOXB1	forkhead box B1	0.011
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.011
KNG1	kininogen 1	0.011
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.011
DLG1	discs, large homolog 1 (Drosophila)	0.011
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.011
ELANE	elastase, neutrophil expressed	0.011
SH2D1A	SH2 domain containing 1A	0.011
GBF1	golgi brefeldin A resistant guanine nucleotide exchange factor 1	0.011
INF2	inverted formin, FH2 and WH2 domain containing	0.011
KRT16	keratin 16	0.011
DNTT	deoxynucleotidyltransferase, terminal	0.011
ASXL1	additional sex combs like 1 (Drosophila)	0.011
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.011
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.011
AMELX	amelogenin, X-linked	0.011
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.011
NNAT	neuronatin	0.011
DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	0.011
MOS	v-mos Moloney murine sarcoma viral oncogene homolog	0.011
ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	0.011
WDTC1	WD and tetratricopeptide repeats 1	0.011
NKX2-1	NK2 homeobox 1	0.011
MASP2	mannan-binding lectin serine peptidase 2	0.011
C3orf27	chromosome 3 open reading frame 27	0.011
HRG	histidine-rich glycoprotein	0.011
LBX1	ladybird homeobox 1	0.011
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.011
TF	transferrin	0.011
PRDM8	PR domain containing 8	0.011
SIX6	SIX homeobox 6	0.010
AGXT2	alanine--glyoxylate aminotransferase 2	0.010
GPR12	G protein-coupled receptor 12	0.010
SLC25A17	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17	0.010
A2M	alpha-2-macroglobulin	0.010
FNIP1	folliculin interacting protein 1	0.010
COPG2	coatomer protein complex, subunit gamma 2	0.010
CCL4	chemokine (C-C motif) ligand 4	0.010
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.010
GJD2	gap junction protein, delta 2, 36kDa	0.010