IMP

Process View

Homo sapiens

19 genes annotated in human

Multi-species View

negative regulation of endocytosis

GO:0045806

Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of endocytosis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of endocytosis" (in gray)

Name	Description	Probability	Func Analog Organism
C1QA	complement component 1, q subcomponent, A chain	0.973	Human
SNX9	sorting nexin 9	0.933	Human
PILRA	paired immunoglobin-like type 2 receptor alpha	0.894
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.743
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.653
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.653	Human
FASLG	Fas ligand (TNF superfamily, member 6)	0.397
TFF1	trefoil factor 1	0.244
APOA1	apolipoprotein A-I	0.223
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.214
CAV1	caveolin 1, caveolae protein, 22kDa	0.195
APOE	apolipoprotein E	0.194
SIGLEC7	sialic acid binding Ig-like lectin 7	0.186	Mouse
HK3	hexokinase 3 (white cell)	0.183
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.129
ANKRD28	ankyrin repeat domain 28	0.119
C19orf50	chromosome 19 open reading frame 50	0.110
ADAM15	ADAM metallopeptidase domain 15	0.109
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.109	Human
GRB2	growth factor receptor-bound protein 2	0.107
CD33	CD33 molecule	0.105
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.094
C1QC	complement component 1, q subcomponent, C chain	0.092	Human
SH3GL2	SH3-domain GRB2-like 2	0.085
CALCOCO2	calcium binding and coiled-coil domain 2	0.084
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.071
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.063	Human
ALB	albumin	0.061
MARCO	macrophage receptor with collagenous structure	0.058
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.057
ITSN1	intersectin 1 (SH3 domain protein)	0.055
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.052
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.051	Mouse
WASL	Wiskott-Aldrich syndrome-like	0.049
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.046
KLC1	kinesin light chain 1	0.045
PTAFR	platelet-activating factor receptor	0.044
HP	haptoglobin	0.042
SIGLEC9	sialic acid binding Ig-like lectin 9	0.041	Mouse
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.041
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.040
APOC1	apolipoprotein C-I	0.038
CAV2	caveolin 2	0.038	Human
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.035
TGIF1	TGFB-induced factor homeobox 1	0.034
A2M	alpha-2-macroglobulin	0.033
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.030
PACSIN3	protein kinase C and casein kinase substrate in neurons 3	0.030	Mouse
MICA	MHC class I polypeptide-related sequence A	0.029
C1QB	complement component 1, q subcomponent, B chain	0.028	Human
DNM2	dynamin 2	0.027
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.027
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.026
APOA2	apolipoprotein A-II	0.025
CTTN	cortactin	0.025
AMPH	amphiphysin	0.024
HIPK3	homeodomain interacting protein kinase 3	0.024
RIN1	Ras and Rab interactor 1	0.024
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.023
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.022
PTPRF	protein tyrosine phosphatase, receptor type, F	0.022
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.022
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.021
CD300A	CD300a molecule	0.021
FYN	FYN oncogene related to SRC, FGR, YES	0.020
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.019
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.019	Mouse
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.019
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.019
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.019
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.019
HCK	hemopoietic cell kinase	0.018
CMKLR1	chemokine-like receptor 1	0.018
SIRPB1	signal-regulatory protein beta 1	0.018
F2R	coagulation factor II (thrombin) receptor	0.017
CYTH4	cytohesin 4	0.017
EIF3L	eukaryotic translation initiation factor 3, subunit L	0.017
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.017
TYK2	tyrosine kinase 2	0.017
ASGR2	asialoglycoprotein receptor 2	0.017
CD300C	CD300c molecule	0.017	Human
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.016	Human
DTX1	deltex homolog 1 (Drosophila)	0.016
TGFBR1	transforming growth factor, beta receptor 1	0.016
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.016	Human
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.016
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.015
VSIG4	V-set and immunoglobulin domain containing 4	0.015
VIM	vimentin	0.015
HIPK2	homeodomain interacting protein kinase 2	0.015
UBASH3B	ubiquitin associated and SH3 domain containing B	0.014
FSTL1	follistatin-like 1	0.014
INPP5K	inositol polyphosphate-5-phosphatase K	0.014
APOC2	apolipoprotein C-II	0.014
FNBP1	formin binding protein 1	0.014
TMSB10	thymosin beta 10	0.014
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.013
FPR1	formyl peptide receptor 1	0.013
NLRP3	NLR family, pyrin domain containing 3	0.013
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.013
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.012
CCR1	chemokine (C-C motif) receptor 1	0.012
MGAT4B	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B	0.012
TREM1	triggering receptor expressed on myeloid cells 1	0.012
CSK	c-src tyrosine kinase	0.012	Rat
ARL3	ADP-ribosylation factor-like 3	0.012
SH3GL3	SH3-domain GRB2-like 3	0.012
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.012
AOAH	acyloxyacyl hydrolase (neutrophil)	0.012
DNM1	dynamin 1	0.012
FPR2	formyl peptide receptor 2	0.012
NINL	ninein-like	0.012
MSR1	macrophage scavenger receptor 1	0.012
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.011
ANKRD24	ankyrin repeat domain 24	0.011
SLAMF8	SLAM family member 8	0.011
TRPM2	transient receptor potential cation channel, subfamily M, member 2	0.011
SIGLEC5	sialic acid binding Ig-like lectin 5	0.011
C14orf1	chromosome 14 open reading frame 1	0.011
CA12	carbonic anhydrase XII	0.011
MPO	myeloperoxidase	0.011
CAMP	cathelicidin antimicrobial peptide	0.011
MSTO1	misato homolog 1 (Drosophila)	0.011
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.011
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.011
PRKCDBP	protein kinase C, delta binding protein	0.011
CLEC4G	C-type lectin domain family 4, member G	0.010
ENG	endoglin	0.010
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.010
WIPI1	WD repeat domain, phosphoinositide interacting 1	0.010
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.010	Human
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.010