IMP

Process View

Homo sapiens

9 genes annotated in human

anterior posterior pattern specification

The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "anterior posterior pattern specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "anterior posterior pattern specification" (in gray)

Name	Description	Probability	Func Analog Organism
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.959	Fly
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.941	Worm
SMAD2	SMAD family member 2	0.299	Mouse
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.297	Worm
JAG1	jagged 1	0.219
SMAD4	SMAD family member 4	0.216	Mouse
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.210	Worm
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.200	Worm
CREBBP	CREB binding protein	0.193
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.124	Fly
HOXB5	homeobox B5	0.109	Mouse
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.108	Worm
ZYX	zyxin	0.100
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.092
BCOR	BCL6 corepressor	0.090
NOTCH1	notch 1	0.080	Zebrafish Mouse Fly
MEOX2	mesenchyme homeobox 2	0.079	Mouse
BMI1	BMI1 polycomb ring finger oncogene	0.073	Mouse
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.071
EIF4A3	eukaryotic translation initiation factor 4A3	0.070	Fly
ATF3	activating transcription factor 3	0.067
FN1	fibronectin 1	0.064	Zebrafish
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.062
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.059
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.056	Fly
GSK3B	glycogen synthase kinase 3 beta	0.054
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.053
HOXD9	homeobox D9	0.051	Mouse
HOXA10	homeobox A10	0.048
LRP6	low density lipoprotein receptor-related protein 6	0.047	Mouse
BMPR1A	bone morphogenetic protein receptor, type IA	0.046	Mouse Fly
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.046
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.043	Mouse
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.040
PSEN1	presenilin 1	0.039	Mouse
TP53	tumor protein p53	0.035	Mouse
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.032
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.031	Fly
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.031
SRPK2	SRSF protein kinase 2	0.030
NOTCH3	notch 3	0.030	Fly
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.029
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.029
HOXA5	homeobox A5	0.029	Mouse
HDAC4	histone deacetylase 4	0.028
SNAP25	synaptosomal-associated protein, 25kDa	0.028
FOXA2	forkhead box A2	0.028	Mouse
GATA4	GATA binding protein 4	0.028	Mouse
QKI	quaking homolog, KH domain RNA binding (mouse)	0.027
SRSF1	serine/arginine-rich splicing factor 1	0.026
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.026
HOXC6	homeobox C6	0.025	Mouse
HOXB9	homeobox B9	0.025	Mouse
FLNA	filamin A, alpha	0.025
TRIP6	thyroid hormone receptor interactor 6	0.024
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.024
PML	promyelocytic leukemia	0.024
MEIS1	Meis homeobox 1	0.024
HOXA11	homeobox A11	0.024	Mouse
HOXB6	homeobox B6	0.023	Mouse
PAX1	paired box 1	0.023	Mouse
NCKAP1	NCK-associated protein 1	0.022	Mouse
HOXB3	homeobox B3	0.021	Mouse
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.021	Mouse
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.021
MLLT1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.021
WNT3A	wingless-type MMTV integration site family, member 3A	0.020	Zebrafish Mouse
HOXA4	homeobox A4	0.020	Mouse
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.020
SMAD3	SMAD family member 3	0.020	Mouse
ZHX1	zinc fingers and homeoboxes 1	0.020
PBX1	pre-B-cell leukemia homeobox 1	0.020	Mouse
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.020
ANAPC7	anaphase promoting complex subunit 7	0.019
MDC1	mediator of DNA-damage checkpoint 1	0.019
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.019
PDX1	pancreatic and duodenal homeobox 1	0.018
RHOA	ras homolog gene family, member A	0.018
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.018	Fly
OCRL	oculocerebrorenal syndrome of Lowe	0.018
APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.017
ANAPC5	anaphase promoting complex subunit 5	0.017
CBX8	chromobox homolog 8	0.017
CHRD	chordin	0.017	Zebrafish Fly
ACVR1	activin A receptor, type I	0.017	Fly
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.017	Worm
MSX1	msh homeobox 1	0.016	Mouse
FLNB	filamin B, beta	0.016
SORBS3	sorbin and SH3 domain containing 3	0.016
SPTBN1	spectrin, beta, non-erythrocytic 1	0.015
SCHIP1	schwannomin interacting protein 1	0.015
ZMYND11	zinc finger, MYND-type containing 11	0.015
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.015
CCNT1	cyclin T1	0.015
XIAP	X-linked inhibitor of apoptosis	0.015
PCGF2	polycomb group ring finger 2	0.015	Mouse
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.015
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.015
PKM2	pyruvate kinase, muscle	0.014
CBX4	chromobox homolog 4	0.014
GDA	guanine deaminase	0.014
TRRAP	transformation/transcription domain-associated protein	0.014
C19orf39	chromosome 19 open reading frame 39	0.014
PAX3	paired box 3	0.014	Mouse
MYOD1	myogenic differentiation 1	0.014
CDK9	cyclin-dependent kinase 9	0.014
CUL4A	cullin 4A	0.014
HOXC8	homeobox C8	0.014	Mouse
ITSN1	intersectin 1 (SH3 domain protein)	0.014
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.013
LMO4	LIM domain only 4	0.013
RNPS1	RNA binding protein S1, serine-rich domain	0.013
HOXC11	homeobox C11	0.013	Mouse
PRKCZ	protein kinase C, zeta	0.012
SNRPD1	small nuclear ribonucleoprotein D1 polypeptide 16kDa	0.012
DAXX	death-domain associated protein	0.012
PTCH1	patched 1	0.012
MEOX1	mesenchyme homeobox 1	0.012	Mouse
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.012
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.012
FZD1	frizzled homolog 1 (Drosophila)	0.012	Human
USP11	ubiquitin specific peptidase 11	0.012
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.012
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.012
HOXA7	homeobox A7	0.012	Mouse
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.012
FZD7	frizzled homolog 7 (Drosophila)	0.011	Human
FBLN1	fibulin 1	0.011
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.011	Fly
LDHA	lactate dehydrogenase A	0.011
JUN	jun proto-oncogene	0.011
HOXA3	homeobox A3	0.011	Mouse
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.011	Fly
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.011
HOXC10	homeobox C10	0.011	Mouse
PRKCI	protein kinase C, iota	0.011
CDX2	caudal type homeobox 2	0.011	Mouse Fly
MEIS2	Meis homeobox 2	0.011
FOXF2	forkhead box F2	0.010
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.010
HOXA6	homeobox A6	0.010	Mouse
SIM2	single-minded homolog 2 (Drosophila)	0.010
SRSF9	serine/arginine-rich splicing factor 9	0.010
TBX5	T-box 5	0.010	Human
ENG	endoglin	0.010
NPTN	neuroplastin	0.010
IRS1	insulin receptor substrate 1	0.010