IMP

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Homo sapiens

4 genes annotated in human

Multi-species View

toll like receptor 2 signaling pathway

GO:0034134

Any series of molecular signals generated as a consequence of binding to toll-like receptor 2.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "toll like receptor 2 signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "toll like receptor 2 signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
MYD88	myeloid differentiation primary response gene (88)	1.000
BIRC3	baculoviral IAP repeat containing 3	1.000
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	1.000	Human
IRAK1	interleukin-1 receptor-associated kinase 1	0.999
TRAF6	TNF receptor-associated factor 6	0.999
IRAK2	interleukin-1 receptor-associated kinase 2	0.998	Human
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.998
TRAF1	TNF receptor-associated factor 1	0.991
BIRC2	baculoviral IAP repeat containing 2	0.977
TRAF3	TNF receptor-associated factor 3	0.950
RIPK2	receptor-interacting serine-threonine kinase 2	0.950
IRAK3	interleukin-1 receptor-associated kinase 3	0.916	Human
PELI3	pellino homolog 3 (Drosophila)	0.832
TRAF2	TNF receptor-associated factor 2	0.751
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.715
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.536
TNIP1	TNFAIP3 interacting protein 1	0.491
ZC3H12A	zinc finger CCCH-type containing 12A	0.452
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.427
IRAK4	interleukin-1 receptor-associated kinase 4	0.326
TLR4	toll-like receptor 4	0.317
SQSTM1	sequestosome 1	0.304
RIPK3	receptor-interacting serine-threonine kinase 3	0.268	Human
FADD	Fas (TNFRSF6)-associated via death domain	0.200
FAS	Fas (TNF receptor superfamily, member 6)	0.188
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.148
TRADD	TNFRSF1A-associated via death domain	0.147
CAV1	caveolin 1, caveolae protein, 22kDa	0.135
TANK	TRAF family member-associated NFKB activator	0.132
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.106
IRF7	interferon regulatory factor 7	0.099
PTPRA	protein tyrosine phosphatase, receptor type, A	0.096
CD40	CD40 molecule, TNF receptor superfamily member 5	0.081
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.078
USP15	ubiquitin specific peptidase 15	0.076
TRIM38	tripartite motif containing 38	0.073
ZC3H12C	zinc finger CCCH-type containing 12C	0.068
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.064
TOLLIP	toll interacting protein	0.060
CFLAR	CASP8 and FADD-like apoptosis regulator	0.059
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.056
PELI2	pellino homolog 2 (Drosophila)	0.054
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.051
TLR2	toll-like receptor 2	0.044
CAV2	caveolin 2	0.038
SAMHD1	SAM domain and HD domain 1	0.036
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.035
NOD2	nucleotide-binding oligomerization domain containing 2	0.034
PELI1	pellino homolog 1 (Drosophila)	0.034
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.032
RIPK4	receptor-interacting serine-threonine kinase 4	0.031	Human
TNF	tumor necrosis factor	0.031
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.030
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.030
CARD11	caspase recruitment domain family, member 11	0.028
INADL	InaD-like (Drosophila)	0.026
KRT8	keratin 8	0.025
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.023
TMEM173	transmembrane protein 173	0.023
CCDC50	coiled-coil domain containing 50	0.023
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.023
ANXA1	annexin A1	0.022
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.021
STK11	serine/threonine kinase 11	0.021
IL1R1	interleukin 1 receptor, type I	0.020
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.020
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.019
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.019
TRAF3IP1	TNF receptor-associated factor 3 interacting protein 1	0.017
TRAF3IP2	TRAF3 interacting protein 2	0.017
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.017
NOD1	nucleotide-binding oligomerization domain containing 1	0.017
BCL10	B-cell CLL/lymphoma 10	0.016
JAK1	Janus kinase 1	0.016
STRADA	STE20-related kinase adaptor alpha	0.015
SPOP	speckle-type POZ protein	0.015
STAP2	signal transducing adaptor family member 2	0.015
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.014
TXN	thioredoxin	0.014
PROCR	protein C receptor, endothelial	0.014
TICAM1	toll-like receptor adaptor molecule 1	0.014
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.013
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.013
CD14	CD14 molecule	0.013
TICAM2	toll-like receptor adaptor molecule 2	0.013
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.011
TNFAIP8	tumor necrosis factor, alpha-induced protein 8	0.011
ZBP1	Z-DNA binding protein 1	0.011
MLKL	mixed lineage kinase domain-like	0.011
DOCK8	dedicator of cytokinesis 8	0.011