IMP

Process View

Homo sapiens

13 genes annotated in human

ureteric bud development

The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ureteric bud development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ureteric bud development" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	0.999	Mouse
SMAD1	SMAD family member 1	0.996	Mouse
SMAD3	SMAD family member 3	0.996	Mouse
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.985
FGF1	fibroblast growth factor 1 (acidic)	0.985
SMAD2	SMAD family member 2	0.983	Mouse
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.964
FGFR1	fibroblast growth factor receptor 1	0.940	Mouse
NRP1	neuropilin 1	0.697
BMPR1A	bone morphogenetic protein receptor, type IA	0.694
EGR3	early growth response 3	0.669	Human
FGF10	fibroblast growth factor 10	0.521	Human
EGR2	early growth response 2	0.489	Human
MEIS1	Meis homeobox 1	0.472
MEIS2	Meis homeobox 2	0.413
MSN	moesin	0.388
EGR1	early growth response 1	0.378	Human
PAX8	paired box 8	0.367
BMP2	bone morphogenetic protein 2	0.338	Human Mouse
PLCG1	phospholipase C, gamma 1	0.314
FGF8	fibroblast growth factor 8 (androgen-induced)	0.291
CCNE1	cyclin E1	0.284
HOXB5	homeobox B5	0.282
RXRA	retinoid X receptor, alpha	0.280
FSTL1	follistatin-like 1	0.278
NOG	noggin	0.278	Mouse
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.245
HOXA10	homeobox A10	0.219
TIMP3	TIMP metallopeptidase inhibitor 3	0.215
MEOX1	mesenchyme homeobox 1	0.210
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.196
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.189
BMP7	bone morphogenetic protein 7	0.179	Mouse
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.174
THBS1	thrombospondin 1	0.172
COL2A1	collagen, type II, alpha 1	0.156
TRPC1	transient receptor potential cation channel, subfamily C, member 1	0.153
FGF2	fibroblast growth factor 2 (basic)	0.146
SMAD4	SMAD family member 4	0.142	Mouse
WNT1	wingless-type MMTV integration site family, member 1	0.141	Human Mouse
FGF3	fibroblast growth factor 3	0.137	Human
FGF18	fibroblast growth factor 18	0.136
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.135
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.129
NKX2-1	NK2 homeobox 1	0.123
MAGED2	melanoma antigen family D, 2	0.116
SKIL	SKI-like oncogene	0.115
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.114
MED25	mediator complex subunit 25	0.113
TGFBR1	transforming growth factor, beta receptor 1	0.103
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.101
CPE	carboxypeptidase E	0.095
ADAM17	ADAM metallopeptidase domain 17	0.094
BMP4	bone morphogenetic protein 4	0.093
NOTCH1	notch 1	0.087
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.084
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.084
ENG	endoglin	0.081
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.078
SRGN	serglycin	0.075
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.075
PGF	placental growth factor	0.073	Mouse
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.073
CXXC5	CXXC finger protein 5	0.072
CREBBP	CREB binding protein	0.072
FGF4	fibroblast growth factor 4	0.066	Human
EID1	EP300 interacting inhibitor of differentiation 1	0.063
WNT7A	wingless-type MMTV integration site family, member 7A	0.062	Human
PARVA	parvin, alpha	0.062
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.062
SMAD9	SMAD family member 9	0.062	Mouse
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.061
LBX1	ladybird homeobox 1	0.060
FGF7	fibroblast growth factor 7	0.057	Human
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.055
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.053
VEGFA	vascular endothelial growth factor A	0.051	Mouse
SIM2	single-minded homolog 2 (Drosophila)	0.050
CSNK1E	casein kinase 1, epsilon	0.046
NCOA1	nuclear receptor coactivator 1	0.044
PAX2	paired box 2	0.044
ECEL1	endothelin converting enzyme-like 1	0.043
TGFB2	transforming growth factor, beta 2	0.043
PTPRB	protein tyrosine phosphatase, receptor type, B	0.042
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.041
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.041
FGFR3	fibroblast growth factor receptor 3	0.040
SFRP1	secreted frizzled-related protein 1	0.039	Mouse
FOXA2	forkhead box A2	0.038
SOX1	SRY (sex determining region Y)-box 1	0.037
BCL2L1	BCL2-like 1	0.037
SMAD5	SMAD family member 5	0.036	Mouse
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.036
ACAN	aggrecan	0.034
TGFB3	transforming growth factor, beta 3	0.033
FOXF1	forkhead box F1	0.033
SOX2	SRY (sex determining region Y)-box 2	0.033
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.032
AQP5	aquaporin 5	0.032
HOXD10	homeobox D10	0.031
FBLN1	fibulin 1	0.030
HNF1A	HNF1 homeobox A	0.029
HOXC8	homeobox C8	0.029
SMAD7	SMAD family member 7	0.027	Mouse
FZD7	frizzled homolog 7 (Drosophila)	0.026
FN1	fibronectin 1	0.026
RAX	retina and anterior neural fold homeobox	0.026
LAPTM5	lysosomal protein transmembrane 5	0.026
HOXD13	homeobox D13	0.026
SPRY2	sprouty homolog 2 (Drosophila)	0.026
FOXF2	forkhead box F2	0.025
INHBB	inhibin, beta B	0.025
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.024
HMGA2	high mobility group AT-hook 2	0.024
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.024
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.024
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.023
C1QL1	complement component 1, q subcomponent-like 1	0.023
BTRC	beta-transducin repeat containing	0.023
GPC3	glypican 3	0.023
CLDN4	claudin 4	0.023
HES2	hairy and enhancer of split 2 (Drosophila)	0.022
WNT10A	wingless-type MMTV integration site family, member 10A	0.022	Human
AR	androgen receptor	0.022
MDFI	MyoD family inhibitor	0.022
CTGF	connective tissue growth factor	0.021
TBX2	T-box 2	0.021
SOX9	SRY (sex determining region Y)-box 9	0.021	Mouse
LHX1	LIM homeobox 1	0.021	Mouse Rat
CALCA	calcitonin-related polypeptide alpha	0.021
BBS10	Bardet-Biedl syndrome 10	0.020
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.020
SP1	Sp1 transcription factor	0.020
ZNF205	zinc finger protein 205	0.020
FRS2	fibroblast growth factor receptor substrate 2	0.020
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.020
GATA2	GATA binding protein 2	0.020
PAX7	paired box 7	0.020
WT1	Wilms tumor 1	0.020
ZNF331	zinc finger protein 331	0.020
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.019
WIF1	WNT inhibitory factor 1	0.019
JAG1	jagged 1	0.019
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.019
CRLF1	cytokine receptor-like factor 1	0.019	Mouse
FOXL1	forkhead box L1	0.018
COL7A1	collagen, type VII, alpha 1	0.018
WNT3	wingless-type MMTV integration site family, member 3	0.018	Human
POU3F2	POU class 3 homeobox 2	0.018
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.018
GJA3	gap junction protein, alpha 3, 46kDa	0.017
ZNF512B	zinc finger protein 512B	0.017
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.017
SNAI1	snail homolog 1 (Drosophila)	0.017
DNAJC1	DnaJ (Hsp40) homolog, subfamily C, member 1	0.017
HOXD9	homeobox D9	0.017
SLIT2	slit homolog 2 (Drosophila)	0.017
EFNA1	ephrin-A1	0.017
NEUROG2	neurogenin 2	0.016
PDX1	pancreatic and duodenal homeobox 1	0.016
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.016
HBEGF	heparin-binding EGF-like growth factor	0.016
SIX3	SIX homeobox 3	0.016
PTHLH	parathyroid hormone-like hormone	0.016
FZD10	frizzled homolog 10 (Drosophila)	0.015
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.015
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.015
ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	0.015
FOXC1	forkhead box C1	0.015	Mouse
HOXD1	homeobox D1	0.015
WNT11	wingless-type MMTV integration site family, member 11	0.015
DLX4	distal-less homeobox 4	0.015
C5orf13	chromosome 5 open reading frame 13	0.015
GFRA1	GDNF family receptor alpha 1	0.015
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.014
WNT2	wingless-type MMTV integration site family member 2	0.014	Human
IHH	Indian hedgehog	0.014
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.014
PAX3	paired box 3	0.014
VSX1	visual system homeobox 1	0.014
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.014
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.014
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.014
BBS1	Bardet-Biedl syndrome 1	0.014
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.014
TFPI2	tissue factor pathway inhibitor 2	0.014
TRAF4	TNF receptor-associated factor 4	0.014
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.014
ITGA8	integrin, alpha 8	0.014
SIX6	SIX homeobox 6	0.013
LDLR	low density lipoprotein receptor	0.013
HOXC5	homeobox C5	0.013
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.013
SMAD6	SMAD family member 6	0.013	Mouse
HOXB1	homeobox B1	0.013
FGFR4	fibroblast growth factor receptor 4	0.013
TADA3	transcriptional adaptor 3	0.013
TCF21	transcription factor 21	0.013	Mouse
TBX5	T-box 5	0.013
EYA1	eyes absent homolog 1 (Drosophila)	0.013
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.013
FBN1	fibrillin 1	0.013
DIO3	deiodinase, iodothyronine, type III	0.013
VEGFC	vascular endothelial growth factor C	0.012
CADM4	cell adhesion molecule 4	0.012
RBMS3	RNA binding motif, single stranded interacting protein 3	0.012
MNX1	motor neuron and pancreas homeobox 1	0.012
NOTCH3	notch 3	0.012
EYA2	eyes absent homolog 2 (Drosophila)	0.012
CLDN7	claudin 7	0.012
JAG2	jagged 2	0.012
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.012
PRRX2	paired related homeobox 2	0.012
MSX1	msh homeobox 1	0.012
COL13A1	collagen, type XIII, alpha 1	0.012
HOXB13	homeobox B13	0.012
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.012
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.012
SSR1	signal sequence receptor, alpha	0.012
CCNB2	cyclin B2	0.011
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.011
NFIB	nuclear factor I/B	0.011
NKX3-2	NK3 homeobox 2	0.011
CLDN1	claudin 1	0.011
FOXD3	forkhead box D3	0.011
SOX11	SRY (sex determining region Y)-box 11	0.011
EFNB3	ephrin-B3	0.011
STC1	stanniocalcin 1	0.011
BHLHE40	basic helix-loop-helix family, member e40	0.011
GAS1	growth arrest-specific 1	0.011
EPHA8	EPH receptor A8	0.011
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.011
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.011
TBCD	tubulin folding cofactor D	0.011
TAOK1	TAO kinase 1	0.011
PGR	progesterone receptor	0.011
HNF1B	HNF1 homeobox B	0.011	Mouse
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.011
MYH10	myosin, heavy chain 10, non-muscle	0.011
GATA4	GATA binding protein 4	0.011
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.011
TBX1	T-box 1	0.011
LAMC3	laminin, gamma 3	0.011
PITX2	paired-like homeodomain 2	0.011
CARD10	caspase recruitment domain family, member 10	0.011
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.010
DCLK1	doublecortin-like kinase 1	0.010
PHOX2A	paired-like homeobox 2a	0.010
GLIS2	GLIS family zinc finger 2	0.010
IER2	immediate early response 2	0.010
ZEB2	zinc finger E-box binding homeobox 2	0.010
FGF19	fibroblast growth factor 19	0.010
FGFBP1	fibroblast growth factor binding protein 1	0.010
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.010
YAP1	Yes-associated protein 1	0.010