IMP

Process View

Homo sapiens

15 genes annotated in human

chromosome condensation

The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "chromosome condensation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "chromosome condensation" (in gray)

Name	Description	Probability	Func Analog Organism
RAD21	RAD21 homolog (S. pombe)	0.925
MCM2	minichromosome maintenance complex component 2	0.883
CDC6	cell division cycle 6 homolog (S. cerevisiae)	0.849
NCAPD2	non-SMC condensin I complex, subunit D2	0.781
NCAPG	non-SMC condensin I complex, subunit G	0.669
CDK2	cyclin-dependent kinase 2	0.668
SMC1A	structural maintenance of chromosomes 1A	0.639
PARP1	poly (ADP-ribose) polymerase 1	0.522
SMC2	structural maintenance of chromosomes 2	0.503
NCAPH	non-SMC condensin I complex, subunit H	0.477
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.449
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.280
LIN9	lin-9 homolog (C. elegans)	0.275
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.206
MCM3	minichromosome maintenance complex component 3	0.197
SMC4	structural maintenance of chromosomes 4	0.193
RPA1	replication protein A1, 70kDa	0.176
TOPBP1	topoisomerase (DNA) II binding protein 1	0.172
BTRC	beta-transducin repeat containing	0.165	Fly
ORC1	origin recognition complex, subunit 1	0.157
CDT1	chromatin licensing and DNA replication factor 1	0.132
NCAPG2	non-SMC condensin II complex, subunit G2	0.121
CDK1	cyclin-dependent kinase 1	0.114	Rat
E2F1	E2F transcription factor 1	0.109
INCENP	inner centromere protein antigens 135/155kDa	0.091
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.090
CCNA2	cyclin A2	0.079
PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.079
TWIST1	twist homolog 1 (Drosophila)	0.075
STAG1	stromal antigen 1	0.070
CCNE1	cyclin E1	0.067
SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.067
WRN	Werner syndrome, RecQ helicase-like	0.063
MCM7	minichromosome maintenance complex component 7	0.061
TRIP6	thyroid hormone receptor interactor 6	0.058
ORC2	origin recognition complex, subunit 2	0.056	Fly
MCM4	minichromosome maintenance complex component 4	0.050
TOP1	topoisomerase (DNA) I	0.047	Yeast Fly
BRCA1	breast cancer 1, early onset	0.047
MDC1	mediator of DNA-damage checkpoint 1	0.046
WAPAL	wings apart-like homolog (Drosophila)	0.043
ORC3	origin recognition complex, subunit 3	0.042
SFPQ	splicing factor proline/glutamine-rich	0.042
NLK	nemo-like kinase	0.041
RPA2	replication protein A2, 32kDa	0.039
SMC3	structural maintenance of chromosomes 3	0.038	Worm
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.037
CDC45	cell division cycle 45 homolog (S. cerevisiae)	0.036	Fly
CCNB2	cyclin B2	0.035
CUL1	cullin 1	0.035
MSH6	mutS homolog 6 (E. coli)	0.034
PCNA	proliferating cell nuclear antigen	0.034
CKAP5	cytoskeleton associated protein 5	0.033
PDS5A	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.033
MCM6	minichromosome maintenance complex component 6	0.032
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.031
KIF11	kinesin family member 11	0.030
STAG2	stromal antigen 2	0.030
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.029
RNF4	ring finger protein 4	0.028
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.027
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.025
TACC3	transforming, acidic coiled-coil containing protein 3	0.024
KIF20A	kinesin family member 20A	0.024
UBA1	ubiquitin-like modifier activating enzyme 1	0.023
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.023
PRC1	protein regulator of cytokinesis 1	0.023
DBF4	DBF4 homolog (S. cerevisiae)	0.023
NCAPH2	non-SMC condensin II complex, subunit H2	0.022
WHSC1	Wolf-Hirschhorn syndrome candidate 1	0.020
MKI67	antigen identified by monoclonal antibody Ki-67	0.020
KNTC1	kinetochore associated 1	0.019
NEB	nebulin	0.018
UNG	uracil-DNA glycosylase	0.018
ORC6	origin recognition complex, subunit 6	0.018
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	0.017
SRRM1	serine/arginine repetitive matrix 1	0.017
CLSPN	claspin	0.015
RACGAP1	Rac GTPase activating protein 1	0.015
FBXW11	F-box and WD repeat domain containing 11	0.015	Fly
SAFB	scaffold attachment factor B	0.015
POLA1	polymerase (DNA directed), alpha 1, catalytic subunit	0.015
CTCF	CCCTC-binding factor (zinc finger protein)	0.015
USPL1	ubiquitin specific peptidase like 1	0.014
BLM	Bloom syndrome, RecQ helicase-like	0.014
HMGB2	high mobility group box 2	0.013
CENPE	centromere protein E, 312kDa	0.013
CDCA8	cell division cycle associated 8	0.013
ANLN	anillin, actin binding protein	0.013
LBR	lamin B receptor	0.013
SKP2	S-phase kinase-associated protein 2 (p45)	0.012
RPA3	replication protein A3, 14kDa	0.012
NCL	nucleolin	0.012
BRCA2	breast cancer 2, early onset	0.012
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.012
CDCA3	cell division cycle associated 3	0.012
FAM46A	family with sequence similarity 46, member A	0.011
RANBP2	RAN binding protein 2	0.011
TTI1	Tel2 interacting protein 1 homolog (S. pombe)	0.011
GPSM2	G-protein signaling modulator 2	0.011
RRM2	ribonucleotide reductase M2	0.011
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.011
PRSS23	protease, serine, 23	0.011
ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3	0.011
CDKN3	cyclin-dependent kinase inhibitor 3	0.011
DFFA	DNA fragmentation factor, 45kDa, alpha polypeptide	0.011
ATAD2	ATPase family, AAA domain containing 2	0.010
ATN1	atrophin 1	0.010
TTK	TTK protein kinase	0.010
SKP1	S-phase kinase-associated protein 1	0.010	Fly
CAPN3	calpain 3, (p94)	0.010
DTL	denticleless homolog (Drosophila)	0.010
MCMBP	minichromosome maintenance complex binding protein	0.010
VPS4A	vacuolar protein sorting 4 homolog A (S. cerevisiae)	0.010
TRIM63	tripartite motif containing 63	0.010