IMP

Process View

Homo sapiens

3 genes annotated in human

Multi-species View

interleukin 2 secretion

GO:0070970

The regulated release of interleukin-2 from a cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "interleukin 2 secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "interleukin 2 secretion" (in gray)

Name	Description	Probability	Func Analog Organism
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.902
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.778
MED15	mediator complex subunit 15	0.773
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.633
TRIM39	tripartite motif containing 39	0.518	Human
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.513
TRIM5	tripartite motif containing 5	0.400	Human
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.382
TRIM21	tripartite motif containing 21	0.340	Human
ZNF263	zinc finger protein 263	0.331
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.324
EGFR	epidermal growth factor receptor	0.303
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.297
WASF1	WAS protein family, member 1	0.296
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.275
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.221
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.200
RIN1	Ras and Rab interactor 1	0.200
ARIH2	ariadne homolog 2 (Drosophila)	0.167
SP100	SP100 nuclear antigen	0.134
IFI16	interferon, gamma-inducible protein 16	0.131
DAXX	death-domain associated protein	0.122
SP110	SP110 nuclear body protein	0.112
TRIM26	tripartite motif containing 26	0.107
SOS1	son of sevenless homolog 1 (Drosophila)	0.102
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.100
TRIM43	tripartite motif containing 43	0.098
MSH4	mutS homolog 4 (E. coli)	0.091
ABI2	abl-interactor 2	0.091
TRIM8	tripartite motif containing 8	0.091
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.091
SPRR2A	small proline-rich protein 2A	0.089
ZHX1	zinc fingers and homeoboxes 1	0.085
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.081
TRIM32	tripartite motif containing 32	0.078
MAVS	mitochondrial antiviral signaling protein	0.069
ZNRF1	zinc and ring finger 1	0.067
TRIM17	tripartite motif containing 17	0.064	Human
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.061
NMI	N-myc (and STAT) interactor	0.058
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.057
PLSCR1	phospholipid scramblase 1	0.056
RNF5	ring finger protein 5	0.056
MSH5	mutS homolog 5 (E. coli)	0.053
TRIM41	tripartite motif containing 41	0.051	Human
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.050
PML	promyelocytic leukemia	0.049
XIAP	X-linked inhibitor of apoptosis	0.048
MCOLN1	mucolipin 1	0.046
ZNF473	zinc finger protein 473	0.044
RNF126	ring finger protein 126	0.042
IRF9	interferon regulatory factor 9	0.041
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.041
FAS	Fas (TNF receptor superfamily, member 6)	0.038
BIRC2	baculoviral IAP repeat containing 2	0.036
MKRN3	makorin ring finger protein 3	0.036
MR1	major histocompatibility complex, class I-related	0.036
BCAR1	breast cancer anti-estrogen resistance 1	0.035
TRIM22	tripartite motif containing 22	0.035	Human
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.034
FADD	Fas (TNFRSF6)-associated via death domain	0.034
PHF11	PHD finger protein 11	0.033
TRIM34	tripartite motif containing 34	0.032
ANXA1	annexin A1	0.032
IFI44	interferon-induced protein 44	0.031
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.031
CHFR	checkpoint with forkhead and ring finger domains	0.031
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.030
RNF114	ring finger protein 114	0.029
UBTD1	ubiquitin domain containing 1	0.028
SAMD9	sterile alpha motif domain containing 9	0.028
IRF2	interferon regulatory factor 2	0.027
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.026
TRIM52	tripartite motif containing 52	0.026
SREBF1	sterol regulatory element binding transcription factor 1	0.024
RNF185	ring finger protein 185	0.024
PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide	0.023
MANF	mesencephalic astrocyte-derived neurotrophic factor	0.023
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.023	Mouse
INPPL1	inositol polyphosphate phosphatase-like 1	0.022
ADAM19	ADAM metallopeptidase domain 19	0.022
ATXN1	ataxin 1	0.022
DTX3L	deltex 3-like (Drosophila)	0.022
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.022
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.021
STAT5A	signal transducer and activator of transcription 5A	0.021
GLA	galactosidase, alpha	0.020
RNF11	ring finger protein 11	0.020
ZNF202	zinc finger protein 202	0.019
TUBGCP4	tubulin, gamma complex associated protein 4	0.019
MEX3B	mex-3 homolog B (C. elegans)	0.019
TRIM25	tripartite motif containing 25	0.018
TRIM6	tripartite motif containing 6	0.018	Human
CTSO	cathepsin O	0.018
PXN	paxillin	0.018
RHAG	Rh-associated glycoprotein	0.018
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.018
ZBTB8A	zinc finger and BTB domain containing 8A	0.018
FGFR1	fibroblast growth factor receptor 1	0.017
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.017
TLR3	toll-like receptor 3	0.017
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.017
PRKCA	protein kinase C, alpha	0.016
RNF130	ring finger protein 130	0.016
BFAR	bifunctional apoptosis regulator	0.016
SHB	Src homology 2 domain containing adaptor protein B	0.016
SHANK3	SH3 and multiple ankyrin repeat domains 3	0.016
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.016
TRIM6-TRIM34	TRIM6-TRIM34 readthrough	0.016
BRAP	BRCA1 associated protein	0.016
PLCD4	phospholipase C, delta 4	0.016
SORBS1	sorbin and SH3 domain containing 1	0.015
TRIM4	tripartite motif containing 4	0.015	Human
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.015
RNF25	ring finger protein 25	0.015
RNF166	ring finger protein 166	0.014
RNF2	ring finger protein 2	0.014
WASF2	WAS protein family, member 2	0.014
RNF10	ring finger protein 10	0.014
SYK	spleen tyrosine kinase	0.014
TDRD7	tudor domain containing 7	0.014
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.014
XAF1	XIAP associated factor 1	0.014
NCKAP1	NCK-associated protein 1	0.013
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.013
STAT1	signal transducer and activator of transcription 1, 91kDa	0.013
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.013
RAD52	RAD52 homolog (S. cerevisiae)	0.013
HIPK2	homeodomain interacting protein kinase 2	0.013
ZCCHC6	zinc finger, CCHC domain containing 6	0.012
MAGEF1	melanoma antigen family F, 1	0.012
MKRN1	makorin ring finger protein 1	0.012
NPVF	neuropeptide VF precursor	0.012
RLIM	ring finger protein, LIM domain interacting	0.012
GRB7	growth factor receptor-bound protein 7	0.011
BIRC8	baculoviral IAP repeat containing 8	0.011
ABR	active BCR-related gene	0.011
BTN2A1	butyrophilin, subfamily 2, member A1	0.011
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.011
SAMD9L	sterile alpha motif domain containing 9-like	0.011
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.011
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.011
BTN3A3	butyrophilin, subfamily 3, member A3	0.011
SPTB	spectrin, beta, erythrocytic	0.011
GIMAP2	GTPase, IMAP family member 2	0.011
SIAH1	seven in absentia homolog 1 (Drosophila)	0.011
RHD	Rh blood group, D antigen	0.011
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.010
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.010
CCDC50	coiled-coil domain containing 50	0.010
TRIM15	tripartite motif containing 15	0.010	Human
MUC1	mucin 1, cell surface associated	0.010
YAP1	Yes-associated protein 1	0.010
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.010
RNF4	ring finger protein 4	0.010