IMP

Process View

Homo sapiens

16 genes annotated in human

regulation of granulocyte chemotaxis

Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of granulocyte chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of granulocyte chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	0.997	Human
CCL5	chemokine (C-C motif) ligand 5	0.997
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.925
CXCL9	chemokine (C-X-C motif) ligand 9	0.872
S100B	S100 calcium binding protein B	0.868	Human
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.847	Human
S100A1	S100 calcium binding protein A1	0.771	Human
S100A16	S100 calcium binding protein A16	0.767	Human
S100A14	S100 calcium binding protein A14	0.734
DPP4	dipeptidyl-peptidase 4	0.538
CCL2	chemokine (C-C motif) ligand 2	0.452	Human
S100A6	S100 calcium binding protein A6	0.447
NCF2	neutrophil cytosolic factor 2	0.440
CCR7	chemokine (C-C motif) receptor 7	0.416
IL8	interleukin 8	0.411
CXCL10	chemokine (C-X-C motif) ligand 10	0.384
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.349	Human
CXCR4	chemokine (C-X-C motif) receptor 4	0.343	Human Zebrafish
IL6	interleukin 6 (interferon, beta 2)	0.331
CCL19	chemokine (C-C motif) ligand 19	0.325
CCL22	chemokine (C-C motif) ligand 22	0.281	Human
CCL13	chemokine (C-C motif) ligand 13	0.244	Human
IFNG	interferon, gamma	0.237
CCL8	chemokine (C-C motif) ligand 8	0.237	Human
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.224
IL2RG	interleukin 2 receptor, gamma	0.214
IL1B	interleukin 1, beta	0.210	Rat
IL2RB	interleukin 2 receptor, beta	0.197
CCR1	chemokine (C-C motif) receptor 1	0.181	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.171
TLR4	toll-like receptor 4	0.170
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.159
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.155
CCL7	chemokine (C-C motif) ligand 7	0.149	Human
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.133
CCL11	chemokine (C-C motif) ligand 11	0.117	Human
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.115
CXCL11	chemokine (C-X-C motif) ligand 11	0.105
CCR4	chemokine (C-C motif) receptor 4	0.103	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.096
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.084
CCL4	chemokine (C-C motif) ligand 4	0.083	Human
IL7R	interleukin 7 receptor	0.083
PLEK	pleckstrin	0.080
CD93	CD93 molecule	0.076
CCL20	chemokine (C-C motif) ligand 20	0.076	Human
C1QA	complement component 1, q subcomponent, A chain	0.073
IL10	interleukin 10	0.069
FPR1	formyl peptide receptor 1	0.064	Human
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.063
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.063
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.062
C5AR1	complement component 5a receptor 1	0.056	Human Mouse
EZR	ezrin	0.050
PLAUR	plasminogen activator, urokinase receptor	0.050
TNF	tumor necrosis factor	0.049
TGFB1	transforming growth factor, beta 1	0.049
CXCL2	chemokine (C-X-C motif) ligand 2	0.048
CCR2	chemokine (C-C motif) receptor 2	0.046	Human
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.045
GZMK	granzyme K (granzyme 3; tryptase II)	0.045
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.043
JAM3	junctional adhesion molecule 3	0.043
CCL3	chemokine (C-C motif) ligand 3	0.041	Human
JAM2	junctional adhesion molecule 2	0.040	Human
SELL	selectin L	0.040	Rat
IL1R2	interleukin 1 receptor, type II	0.040
VCAN	versican	0.039
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.037
IL1RN	interleukin 1 receptor antagonist	0.037
CD163	CD163 molecule	0.036
CYBB	cytochrome b-245, beta polypeptide	0.036
TREM1	triggering receptor expressed on myeloid cells 1	0.033
CLEC7A	C-type lectin domain family 7, member A	0.032
AGER	advanced glycosylation end product-specific receptor	0.031
CXCL3	chemokine (C-X-C motif) ligand 3	0.030
SELE	selectin E	0.030
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.029
FYN	FYN oncogene related to SRC, FGR, YES	0.029
IL1R1	interleukin 1 receptor, type I	0.028
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.028
CLEC4A	C-type lectin domain family 4, member A	0.027
VCAM1	vascular cell adhesion molecule 1	0.027
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.027
SFRP4	secreted frizzled-related protein 4	0.026
RHOA	ras homolog gene family, member A	0.026
RGS1	regulator of G-protein signaling 1	0.026
BCL2A1	BCL2-related protein A1	0.026
RHOC	ras homolog gene family, member C	0.026
TLR2	toll-like receptor 2	0.025
FKBP4	FK506 binding protein 4, 59kDa	0.025
SRGN	serglycin	0.025
S100P	S100 calcium binding protein P	0.025	Human
CXCL5	chemokine (C-X-C motif) ligand 5	0.024
AREG	amphiregulin	0.024
BAK1	BCL2-antagonist/killer 1	0.024
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.024
AQP9	aquaporin 9	0.023
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.022
CD40LG	CD40 ligand	0.022
IDE	insulin-degrading enzyme	0.022
AEBP1	AE binding protein 1	0.022
CD86	CD86 molecule	0.022
C3AR1	complement component 3a receptor 1	0.021	Human Mouse
IRAK4	interleukin-1 receptor-associated kinase 4	0.021
CCR6	chemokine (C-C motif) receptor 6	0.020	Human
ALOX5	arachidonate 5-lipoxygenase	0.020
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.020
CXCL12	chemokine (C-X-C motif) ligand 12	0.020	Zebrafish
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.020
S100A11	S100 calcium binding protein A11	0.020
CD83	CD83 molecule	0.020
IRAK2	interleukin-1 receptor-associated kinase 2	0.020
CDH5	cadherin 5, type 2 (vascular endothelium)	0.019
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.018
HCK	hemopoietic cell kinase	0.018
C2	complement component 2	0.018
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.018
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.018
GPR109B	G protein-coupled receptor 109B	0.018
ADAMDEC1	ADAM-like, decysin 1	0.018
NCF4	neutrophil cytosolic factor 4, 40kDa	0.018
IL18RAP	interleukin 18 receptor accessory protein	0.018
IRF4	interferon regulatory factor 4	0.017
DARC	Duffy blood group, chemokine receptor	0.017
PDZK1	PDZ domain containing 1	0.017
CD14	CD14 molecule	0.017
CCR3	chemokine (C-C motif) receptor 3	0.017	Human
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.016
SLAMF8	SLAM family member 8	0.016
C1QB	complement component 1, q subcomponent, B chain	0.016
S100A4	S100 calcium binding protein A4	0.016
S100A9	S100 calcium binding protein A9	0.016
PLAU	plasminogen activator, urokinase	0.016
CCL21	chemokine (C-C motif) ligand 21	0.016
C3	complement component 3	0.016
FYB	FYN binding protein	0.016
SAMHD1	SAM domain and HD domain 1	0.016
S100A12	S100 calcium binding protein A12	0.015	Human
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.015
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.015	Mouse
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.015
C1QC	complement component 1, q subcomponent, C chain	0.015
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.015
FPR3	formyl peptide receptor 3	0.015	Human
MSN	moesin	0.014
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.014
MSR1	macrophage scavenger receptor 1	0.014
S100A8	S100 calcium binding protein A8	0.014
CYTIP	cytohesin 1 interacting protein	0.014
CXCR2	chemokine (C-X-C motif) receptor 2	0.014	Human Rat
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.014
CH25H	cholesterol 25-hydroxylase	0.014
INHBA	inhibin, beta A	0.014
PI3	peptidase inhibitor 3, skin-derived	0.013
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.013
NLRP3	NLR family, pyrin domain containing 3	0.013
CLC	Charcot-Leyden crystal protein	0.013
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.013
CD69	CD69 molecule	0.013
IDO1	indoleamine 2,3-dioxygenase 1	0.013
CD68	CD68 molecule	0.013
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.013
MPEG1	macrophage expressed 1	0.013
ICAM1	intercellular adhesion molecule 1	0.013
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.013
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.013
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.013
CLEC5A	C-type lectin domain family 5, member A	0.013
MYD88	myeloid differentiation primary response gene (88)	0.012
F13A1	coagulation factor XIII, A1 polypeptide	0.012
CLEC4E	C-type lectin domain family 4, member E	0.012
IL21R	interleukin 21 receptor	0.012
CD28	CD28 molecule	0.012
CTNND1	catenin (cadherin-associated protein), delta 1	0.012
SOCS3	suppressor of cytokine signaling 3	0.012
FFAR2	free fatty acid receptor 2	0.012
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.012
APLNR	apelin receptor	0.011
CXCR3	chemokine (C-X-C motif) receptor 3	0.011	Human
JUP	junction plakoglobin	0.011
GRAP2	GRB2-related adaptor protein 2	0.011
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.011
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	0.011
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.011
CSF1R	colony stimulating factor 1 receptor	0.011	Zebrafish
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.011	Human
FBLN2	fibulin 2	0.011
CLEC10A	C-type lectin domain family 10, member A	0.010
DPT	dermatopontin	0.010
JAK1	Janus kinase 1	0.010
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.010
S100A2	S100 calcium binding protein A2	0.010	Human
ARRB2	arrestin, beta 2	0.010
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.010