IMP
Process View
activation of jnkk activity
The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "activation of jnkk activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 1.000 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.999 | ||
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.996 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.996 | ||
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.988 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.976 | ||
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.974 | ||
| GBP3 | guanylate binding protein 3 | 0.962 | ||
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.873 | ||
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.724 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.662 | ||
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.442 | ||
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.437 | Fly | |
| BECN1 | beclin 1, autophagy related | 0.411 | ||
| PPP6C | protein phosphatase 6, catalytic subunit | 0.393 | ||
| FKBP5 | FK506 binding protein 5 | 0.386 | ||
| NLK | nemo-like kinase | 0.347 | ||
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.333 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.329 | ||
| MAP2K7 | mitogen-activated protein kinase kinase 7 | 0.298 | ||
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.221 | ||
| CHUK | conserved helix-loop-helix ubiquitous kinase | 0.218 | ||
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.207 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.204 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.186 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.149 | ||
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | 0.142 | ||
| MOBKL1A | MOB1, Mps One Binder kinase activator-like 1A (yeast) | 0.137 | ||
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.134 | ||
| TUBB8 | tubulin, beta 8 | 0.128 | ||
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.102 | ||
| SQSTM1 | sequestosome 1 | 0.101 | ||
| RNF19A | ring finger protein 19A | 0.094 | ||
| CLTC | clathrin, heavy chain (Hc) | 0.091 | ||
| MAPK9 | mitogen-activated protein kinase 9 | 0.088 | ||
| PPP5C | protein phosphatase 5, catalytic subunit | 0.087 | ||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.086 | Rat | |
| PLD2 | phospholipase D2 | 0.063 | ||
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.061 | ||
| EPRS | glutamyl-prolyl-tRNA synthetase | 0.046 | ||
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.043 | ||
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.032 | ||
| TRAF2 | TNF receptor-associated factor 2 | 0.031 | ||
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.028 | ||
| TRIP10 | thyroid hormone receptor interactor 10 | 0.025 | ||
| ZNF746 | zinc finger protein 746 | 0.025 | ||
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.023 | ||
| ARRB2 | arrestin, beta 2 | 0.023 | ||
| RGS2 | regulator of G-protein signaling 2, 24kDa | 0.022 | ||
| RHOG | ras homolog gene family, member G (rho G) | 0.022 | ||
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.021 | ||
| HSPA8 | heat shock 70kDa protein 8 | 0.021 | ||
| HSPA1L | heat shock 70kDa protein 1-like | 0.020 | ||
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.019 | ||
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.019 | ||
| MAPK6 | mitogen-activated protein kinase 6 | 0.018 | ||
| JUN | jun proto-oncogene | 0.018 | ||
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.018 | ||
| DST | dystonin | 0.017 | ||
| FLNB | filamin B, beta | 0.017 | ||
| MAPK14 | mitogen-activated protein kinase 14 | 0.016 | ||
| ARRB1 | arrestin, beta 1 | 0.016 | ||
| NCOA3 | nuclear receptor coactivator 3 | 0.016 | ||
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.016 | ||
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.016 | ||
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.015 | ||
| NUMBL | numb homolog (Drosophila)-like | 0.014 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.014 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.013 | ||
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.013 | ||
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.013 | ||
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.013 | ||
| TBC1D10B | TBC1 domain family, member 10B | 0.013 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.012 | ||
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.012 | ||
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.012 | ||
| VRK2 | vaccinia related kinase 2 | 0.012 | ||
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.011 | ||
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B | 0.011 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.011 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.011 | ||
| ACTG1 | actin, gamma 1 | 0.011 | ||
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.010 |