IMP
Process View
spleen development
The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "spleen development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.946 | ||
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.929 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.923 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.865 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.717 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.658 | ||
| BCL2L1 | BCL2-like 1 | 0.464 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.385 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.373 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.193 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.190 | ||
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.184 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.181 | ||
| TBX5 | T-box 5 | 0.165 | ||
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.145 | ||
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.137 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.127 | Mouse | |
| MEIS1 | Meis homeobox 1 | 0.110 | ||
| MEIS2 | Meis homeobox 2 | 0.094 | ||
| DLG1 | discs, large homolog 1 (Drosophila) | 0.086 | ||
| FADD | Fas (TNFRSF6)-associated via death domain | 0.067 | Mouse | |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.061 | ||
| HOXD9 | homeobox D9 | 0.059 | ||
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.059 | ||
| BID | BH3 interacting domain death agonist | 0.058 | ||
| BTRC | beta-transducin repeat containing | 0.055 | ||
| TNIP2 | TNFAIP3 interacting protein 2 | 0.050 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.047 | ||
| CCND1 | cyclin D1 | 0.035 | ||
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.034 | ||
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.033 | ||
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.032 | ||
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.030 | ||
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.030 | ||
| BAX | BCL2-associated X protein | 0.028 | ||
| PAX8 | paired box 8 | 0.027 | ||
| WASF1 | WAS protein family, member 1 | 0.026 | ||
| ZNF282 | zinc finger protein 282 | 0.025 | ||
| BAD | BCL2-associated agonist of cell death | 0.025 | ||
| GATA4 | GATA binding protein 4 | 0.024 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.024 | ||
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.023 | ||
| FOXA2 | forkhead box A2 | 0.022 | ||
| TNIP1 | TNFAIP3 interacting protein 1 | 0.020 | ||
| NCOA7 | nuclear receptor coactivator 7 | 0.019 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.019 | ||
| NOTCH1 | notch 1 | 0.018 | ||
| SPRR2D | small proline-rich protein 2D | 0.018 | ||
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.017 | ||
| SLC4A1 | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 0.017 | ||
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.017 | ||
| TARBP2 | TAR (HIV-1) RNA binding protein 2 | 0.017 | ||
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.017 | ||
| BCL2L2 | BCL2-like 2 | 0.017 | ||
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.016 | ||
| BCL10 | B-cell CLL/lymphoma 10 | 0.016 | ||
| MYH10 | myosin, heavy chain 10, non-muscle | 0.016 | ||
| GOLM1 | golgi membrane protein 1 | 0.015 | ||
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 0.015 | ||
| NFIB | nuclear factor I/B | 0.015 | ||
| CCDC85B | coiled-coil domain containing 85B | 0.014 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.014 | ||
| MBD4 | methyl-CpG binding domain protein 4 | 0.014 | ||
| JUND | jun D proto-oncogene | 0.014 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.014 | ||
| MAPK12 | mitogen-activated protein kinase 12 | 0.014 | ||
| SETD7 | SET domain containing (lysine methyltransferase) 7 | 0.013 | ||
| ABI2 | abl-interactor 2 | 0.013 | ||
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.013 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.013 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.013 | ||
| KIAA1267 | KIAA1267 | 0.012 | ||
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.012 | ||
| HOXB3 | homeobox B3 | 0.012 | ||
| NAF1 | nuclear assembly factor 1 homolog (S. cerevisiae) | 0.012 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.012 | ||
| CUX1 | cut-like homeobox 1 | 0.012 | ||
| KDM5A | lysine (K)-specific demethylase 5A | 0.012 | ||
| NKX6-1 | NK6 homeobox 1 | 0.012 | ||
| BAK1 | BCL2-antagonist/killer 1 | 0.012 | ||
| TP73 | tumor protein p73 | 0.012 | ||
| FKBP8 | FK506 binding protein 8, 38kDa | 0.011 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.011 | ||
| FNBP1 | formin binding protein 1 | 0.011 | ||
| FOXC1 | forkhead box C1 | 0.011 | ||
| C19orf25 | chromosome 19 open reading frame 25 | 0.011 | ||
| PRKCQ | protein kinase C, theta | 0.011 | ||
| E2F3 | E2F transcription factor 3 | 0.011 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.011 | ||
| LMO4 | LIM domain only 4 | 0.011 | ||
| SPRR2A | small proline-rich protein 2A | 0.011 | ||
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) | 0.011 | ||
| CIZ1 | CDKN1A interacting zinc finger protein 1 | 0.011 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.010 | ||
| BBC3 | BCL2 binding component 3 | 0.010 | ||
| SHB | Src homology 2 domain containing adaptor protein B | 0.010 | ||
| TGIF1 | TGFB-induced factor homeobox 1 | 0.010 | ||
| EP300 | E1A binding protein p300 | 0.010 | ||
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | 0.010 | ||
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 0.010 | ||
| PDX1 | pancreatic and duodenal homeobox 1 | 0.010 | ||
| HSPA1L | heat shock 70kDa protein 1-like | 0.010 |