IMP

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Mus musculus

2 genes annotated in mouse

astrocyte activation

A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "astrocyte activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "astrocyte activation" (in gray)

Name	Description	Probability	Func Analog Organism
Fgfr2	fibroblast growth factor receptor 2	0.990
Foxc1	forkhead box C1	0.924
Sox9	SRY-box containing gene 9	0.904
Shh	sonic hedgehog	0.899
Vegfa	vascular endothelial growth factor A	0.860
Bmp4	bone morphogenetic protein 4	0.855
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.708
Chrd	chordin	0.698
Tgfb2	transforming growth factor, beta 2	0.675
Nf1	neurofibromatosis 1	0.592
Foxc2	forkhead box C2	0.590
Prrx1	paired related homeobox 1	0.559
Tcfap2a	transcription factor AP-2, alpha	0.545
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.536
Ednra	endothelin receptor type A	0.523
Rxra	retinoid X receptor alpha	0.506
Pitx2	paired-like homeodomain transcription factor 2	0.475
Nos3	nitric oxide synthase 3, endothelial cell	0.475
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.433	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.405
Fgfr1	fibroblast growth factor receptor 1	0.359
Eya1	eyes absent 1 homolog (Drosophila)	0.320
Tbx1	T-box 1	0.320
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.314
Pax3	paired box gene 3	0.312
Agtr1a	angiotensin II receptor, type 1a	0.310
Gsc	goosecoid homeobox	0.286
Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	0.276	Mouse
Msx1	homeobox, msh-like 1	0.250
Msx2	homeobox, msh-like 2	0.237
Rarb	retinoic acid receptor, beta	0.233
Bmp7	bone morphogenetic protein 7	0.232
Apoa1	apolipoprotein A-I	0.229
Gli2	GLI-Kruppel family member GLI2	0.225
Gli3	GLI-Kruppel family member GLI3	0.221
Ece1	endothelin converting enzyme 1	0.201
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.172
Vangl2	vang-like 2 (van gogh, Drosophila)	0.171
Jag1	jagged 1	0.158
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.157
Rarg	retinoic acid receptor, gamma	0.154
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.145
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.126
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.118
Zeb1	zinc finger E-box binding homeobox 1	0.117
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.109
Disp1	dispatched homolog 1 (Drosophila)	0.103
Rara	retinoic acid receptor, alpha	0.097
Meox2	mesenchyme homeobox 2	0.094
Dlx5	distal-less homeobox 5	0.094
Fga	fibrinogen alpha chain	0.093
Gja1	gap junction protein, alpha 1	0.091
Ahsg	alpha-2-HS-glycoprotein	0.086
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.085
Ren1	renin 1 structural	0.084
Acvr1	activin A receptor, type 1	0.083
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.078
Tgfbr2	transforming growth factor, beta receptor II	0.073
Mn1	meningioma 1	0.071
Fgfr3	fibroblast growth factor receptor 3	0.070
F9	coagulation factor IX	0.062
Runx2	runt related transcription factor 2	0.061
Prrx2	paired related homeobox 2	0.060
Ptch1	patched homolog 1	0.060
Bmper	BMP-binding endothelial regulator	0.060
Fgf8	fibroblast growth factor 8	0.059
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.058
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.058
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.056
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.055
Lepr	leptin receptor	0.053
Hp	haptoglobin	0.050
Ctnnb1	catenin (cadherin associated protein), beta 1	0.050
C4b	complement component 4B (Childo blood group)	0.049
Gc	group specific component	0.047
Lmna	lamin A	0.047
Hand1	heart and neural crest derivatives expressed transcript 1	0.046
Cp	ceruloplasmin	0.046
Alx1	ALX homeobox 1	0.046
F2	coagulation factor II	0.044
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.044
Otx2	orthodenticle homolog 2 (Drosophila)	0.044
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.043
Bmp2	bone morphogenetic protein 2	0.043
Egfr	epidermal growth factor receptor	0.042	Rat
Il1r1	interleukin 1 receptor, type I	0.038
Alb	albumin	0.038
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.038
Fgg	fibrinogen gamma chain	0.036
Npr2	natriuretic peptide receptor 2	0.036
Hamp	hepcidin antimicrobial peptide	0.035
Lbp	lipopolysaccharide binding protein	0.034
Ptgs2	prostaglandin-endoperoxide synthase 2	0.033
Akr1c6	aldo-keto reductase family 1, member C6	0.033
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.033
Crp	C-reactive protein, pentraxin-related	0.032
Tdo2	tryptophan 2,3-dioxygenase	0.031
Hoxa3	homeobox A3	0.030
Apoe	apolipoprotein E	0.030
Mkl2	MKL/myocardin-like 2	0.029
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.029
Saa4	serum amyloid A 4	0.029
Cfb	complement factor B	0.028
Isl1	ISL1 transcription factor, LIM/homeodomain	0.028
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.028
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.028
Sardh	sarcosine dehydrogenase	0.027
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.027
Lrp6	low density lipoprotein receptor-related protein 6	0.027
G6pc	glucose-6-phosphatase, catalytic	0.027
Apof	apolipoprotein F	0.025
Sos1	son of sevenless homolog 1 (Drosophila)	0.025
Sox4	SRY-box containing gene 4	0.025
Mup4	major urinary protein 4	0.025
F10	coagulation factor X	0.024
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.024
C1ra	complement component 1, r subcomponent A	0.024
Gcgr	glucagon receptor	0.024
Apoh	apolipoprotein H	0.024
Tgfa	transforming growth factor alpha	0.024
Shc1	src homology 2 domain-containing transforming protein C1	0.023
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.023
Errfi1	ERBB receptor feedback inhibitor 1	0.022
Gata4	GATA binding protein 4	0.022
Klf3	Kruppel-like factor 3 (basic)	0.022
Otc	ornithine transcarbamylase	0.022
Nos1	nitric oxide synthase 1, neuronal	0.022
C3	complement component 3	0.021
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.021
Apcs	serum amyloid P-component	0.021
Mup3	major urinary protein 3	0.020
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.020
Ang2	angiogenin, ribonuclease A family, member 2	0.020
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.019	Mouse
Twist2	twist homolog 2 (Drosophila)	0.019
Trp53	transformation related protein 53	0.019
Plg	plasminogen	0.019
Kng1	kininogen 1	0.019
Hpx	hemopexin	0.019
Dmgdh	dimethylglycine dehydrogenase precursor	0.019
C2	complement component 2 (within H-2S)	0.018
Adam17	a disintegrin and metallopeptidase domain 17	0.018
Chd7	chromodomain helicase DNA binding protein 7	0.017
Foxg1	forkhead box G1	0.017
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.017
Esr1	estrogen receptor 1 (alpha)	0.016
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.016
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.016	Mouse
Apoa5	apolipoprotein A-V	0.016
Azgp1	alpha-2-glycoprotein 1, zinc	0.015
Gpr182	G protein-coupled receptor 182	0.014
Itih2	inter-alpha trypsin inhibitor, heavy chain 2	0.014
Vtn	vitronectin	0.014
Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	0.014	Mouse
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.014
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.014
Hrg	histidine-rich glycoprotein	0.014
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.014
Fgb	fibrinogen beta chain	0.014
Apoc4	apolipoprotein C-IV	0.014
Pkd1	polycystic kidney disease 1 homolog	0.013
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.013
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.013
Plag1	pleiomorphic adenoma gene 1	0.013
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.013
Osmr	oncostatin M receptor	0.013
Hoxa1	homeobox A1	0.013
Qsox1	quiescin Q6 sulfhydryl oxidase 1	0.013
Uox	urate oxidase	0.013
Inhbc	inhibin beta-C	0.013
Col1a1	collagen, type I, alpha 1	0.013
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.013
Pzp	pregnancy zone protein	0.013
Steap4	STEAP family member 4	0.013
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.012
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.012
Masp2	mannan-binding lectin serine peptidase 2	0.012
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.012	Mouse
Gm4788	predicted gene 4788	0.012
Prg4	proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)	0.012
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.012
Mbl1	mannose-binding lectin (protein A) 1	0.012
Ppara	peroxisome proliferator activated receptor alpha	0.012
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.012
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.012
Tmem79	transmembrane protein 79	0.012
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.012
Onecut1	one cut domain, family member 1	0.011
Apoa2	apolipoprotein A-II	0.011
Dsg4	desmoglein 4	0.011
Fam20c	family with sequence similarity 20, member C	0.011
Nnmt	nicotinamide N-methyltransferase	0.011
Tbx15	T-box 15	0.011
Ccl9	chemokine (C-C motif) ligand 9	0.011
Saa3	serum amyloid A 3	0.011
Saa1	serum amyloid A 1	0.011
Fgf10	fibroblast growth factor 10	0.011
Mesp1	mesoderm posterior 1	0.011
Trfr2	transferrin receptor 2	0.011
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.011
C9	complement component 9	0.011
Mocs1	molybdenum cofactor synthesis 1	0.011
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.010
Vav2	vav 2 oncogene	0.010
Sntb1	syntrophin, basic 1	0.010