IMP

Process View

Mus musculus

22 genes annotated in mouse

tetrapyrrole metabolic process

The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tetrapyrrole metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "tetrapyrrole metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Spna1	spectrin alpha 1	1.000
Ank1	ankyrin 1, erythroid	1.000
Hbb-b1	hemoglobin, beta adult major chain	0.996
Hbb-b2	hemoglobin, beta adult minor chain	0.956
Spnb1	spectrin beta 1	0.923
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.875
Klf1	Kruppel-like factor 1 (erythroid)	0.759
Exoc6	exocyst complex component 6	0.616
Cps1	carbamoyl-phosphate synthetase 1	0.594
Epb4.1	erythrocyte protein band 4.1	0.593
Pklr	pyruvate kinase liver and red blood cell	0.501
Add2	adducin 2 (beta)	0.494
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.476	Mouse
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.473
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.412	Mouse
Ahsp	alpha hemoglobin stabilizing protein	0.387
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.364
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.348	Mouse
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.335
Crp	C-reactive protein, pentraxin-related	0.274
Fech	ferrochelatase	0.263
Slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.254
Cyp2b9	cytochrome P450, family 2, subfamily b, polypeptide 9	0.246	Mouse
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.242
Keg1	kidney expressed gene 1	0.208
Mup5	major urinary protein 5	0.200
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.186
Ttc7	tetratricopeptide repeat domain 7	0.178
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.169
F9	coagulation factor IX	0.167
G6pc	glucose-6-phosphatase, catalytic	0.163
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.154	Mouse
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.149	Mouse
Cyp2c39	cytochrome P450, family 2, subfamily c, polypeptide 39	0.144	Mouse
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.140	Mouse
Azgp1	alpha-2-glycoprotein 1, zinc	0.137
Hba-a2	hemoglobin alpha, adult chain 2	0.135
Cyp2c54	cytochrome P450, family 2, subfamily c, polypeptide 54	0.125	Mouse
Uros	uroporphyrinogen III synthase	0.123
Akr1c6	aldo-keto reductase family 1, member C6	0.121
Tmprss6	transmembrane serine protease 6	0.105
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.103
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.097
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.094	Mouse
Epor	erythropoietin receptor	0.093
Aadac	arylacetamide deacetylase (esterase)	0.089
Hrg	histidine-rich glycoprotein	0.089
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.087
Gsta2	glutathione S-transferase, alpha 2 (Yc2)	0.086
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.085
Lect2	leukocyte cell-derived chemotaxin 2	0.083
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.078
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.078
Otc	ornithine transcarbamylase	0.074
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.071
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.069
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.069
Cfhr1	complement factor H-related 1	0.064
Upp2	uridine phosphorylase 2	0.062
Alb	albumin	0.061
Cat	catalase	0.060
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.059
Hgd	homogentisate 1, 2-dioxygenase	0.057
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.056
Pigr	polymeric immunoglobulin receptor	0.056
Tat	tyrosine aminotransferase	0.054
Krtap6-1	keratin associated protein 6-1	0.053
Cd59b	CD59b antigen	0.052
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.052
Cml2	camello-like 2	0.052
Spna2	spectrin alpha 2	0.050	Mouse
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.049
Pon1	paraoxonase 1	0.049
Hfe2	hemochromatosis type 2 (juvenile) (human homolog)	0.048
Mbl2	mannose-binding lectin (protein C) 2	0.047
C9	complement component 9	0.047
Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.047
Cyp2b13	cytochrome P450, family 2, subfamily b, polypeptide 13	0.047
Beta-s	hemoglobin subunit beta-1-like	0.046
Vnn3	vanin 3	0.046
Bhmt	betaine-homocysteine methyltransferase	0.046
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.045
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.045
Sult2a2	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2	0.044
Dmgdh	dimethylglycine dehydrogenase precursor	0.043
Mat1a	methionine adenosyltransferase I, alpha	0.043
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.043
Sult1d1	sulfotransferase family 1D, member 1	0.043
Afm	afamin	0.042
Hsd3b4	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4	0.042
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.042
Slco1b2	solute carrier organic anion transporter family, member 1b2	0.041
Inmt	indolethylamine N-methyltransferase	0.039
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.039
Fmo3	flavin containing monooxygenase 3	0.038
Tdo2	tryptophan 2,3-dioxygenase	0.037
Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	0.036
Apoh	apolipoprotein H	0.036
Rdh7	retinol dehydrogenase 7	0.036
Cp	ceruloplasmin	0.035
Macf1	microtubule-actin crosslinking factor 1	0.034
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.034
Hmbs	hydroxymethylbilane synthase	0.033
Pnpo	pyridoxine 5'-phosphate oxidase	0.032
Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.032
Akr1d1	aldo-keto reductase family 1, member D1	0.032
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.031
Apoc4	apolipoprotein C-IV	0.031
Dhrs4	dehydrogenase/reductase (SDR family) member 4	0.031
F13b	coagulation factor XIII, beta subunit	0.030
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.030	Mouse
Pah	phenylalanine hydroxylase	0.030
Sult1b1	sulfotransferase family 1B, member 1	0.030
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.029
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.029
Ugt3a2	UDP glycosyltransferases 3 family, polypeptide A2	0.029
Acot12	acyl-CoA thioesterase 12	0.028
Olfr1509	olfactory receptor 1509	0.028
Ces1g	carboxylesterase 1G	0.028
Glrx5	glutaredoxin 5 homolog (S. cerevisiae)	0.027
Fbp1	fructose bisphosphatase 1	0.027
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.027
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.026
Hfe	hemochromatosis	0.026
1300017J02Rik	RIKEN cDNA 1300017J02 gene	0.026
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.026
Etfb	electron transferring flavoprotein, beta polypeptide	0.025
Ces3a	carboxylesterase 3A	0.025
F7	coagulation factor VII	0.025
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.025	Mouse
Saa2	serum amyloid A 2	0.024
Mocs1	molybdenum cofactor synthesis 1	0.024
Lipc	lipase, hepatic	0.023
Gc	group specific component	0.022
Ttc3	tetratricopeptide repeat domain 3	0.022
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.022	Mouse
Vsig4	V-set and immunoglobulin domain containing 4	0.022
Grb7	growth factor receptor bound protein 7	0.022
Defb1	defensin beta 1	0.022
Bhmt2	betaine-homocysteine methyltransferase 2	0.022
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.022
Cideb	cell death-inducing DNA fragmentation factor, alpha subunit-like effector B	0.022
Alas2	aminolevulinic acid synthase 2, erythroid	0.021
Tmprss15	transmembrane protease, serine 15	0.021
Cyp2c68	cytochrome P450, family 2, subfamily c, polypeptide 68	0.021
Slco1a4	solute carrier organic anion transporter family, member 1a4	0.021	Mouse
Dync1h1	dynein cytoplasmic 1 heavy chain 1	0.021
Ikbkg	inhibitor of kappaB kinase gamma	0.021
Mup3	major urinary protein 3	0.021
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.021
Cyp2c55	cytochrome P450, family 2, subfamily c, polypeptide 55	0.020
Gypa	glycophorin A	0.020
Akr1c21	aldo-keto reductase family 1, member C21	0.020
Fam195a	family with sequence similarity 195, member A	0.020
Gpr12	G-protein coupled receptor 12	0.020
Glyat	glycine-N-acyltransferase	0.020
Ugt3a1	UDP glycosyltransferases 3 family, polypeptide A1	0.020
Gstm3	glutathione S-transferase, mu 3	0.020
Cyp4a31	cytochrome P450, family 4, subfamily a, polypeptide 31	0.019
Kifap3	kinesin-associated protein 3	0.019
Heph	hephaestin	0.019
Cyp4a12a	cytochrome P450, family 4, subfamily a, polypeptide 12a	0.019
Aldob	aldolase B, fructose-bisphosphate	0.019
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.019
Gm14743	predicted gene 14743	0.019
Taldo1	transaldolase 1	0.019
Sec14l4	SEC14-like 4 (S. cerevisiae)	0.019
Aldh8a1	aldehyde dehydrogenase 8 family, member A1	0.019
Apcs	serum amyloid P-component	0.019
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.019
Snca	synuclein, alpha	0.019
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.019
Mug1	murinoglobulin 1	0.019
Pnpla6	patatin-like phospholipase domain containing 6	0.019
Spnb2	spectrin beta 2	0.018	Mouse
Acot3	acyl-CoA thioesterase 3	0.018
Avpr1a	arginine vasopressin receptor 1A	0.018
Bche	butyrylcholinesterase	0.018
Thrb	thyroid hormone receptor beta	0.018
Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37	0.018	Mouse
Ces2a	carboxylesterase 2A	0.018
Car5a	carbonic anhydrase 5a, mitochondrial	0.017
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.017
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.017
Tfrc	transferrin receptor	0.017
Cd5l	CD5 antigen-like	0.017
Mprip	myosin phosphatase Rho interacting protein	0.017
Ebp	phenylalkylamine Ca2+ antagonist (emopamil) binding protein	0.017
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.017
Myh14	myosin, heavy polypeptide 14	0.016
Ces1d	carboxylesterase 1D	0.016
Ugt2b38	UDP glucuronosyltransferase 2 family, polypeptide B38	0.016
Ttc36	tetratricopeptide repeat domain 36	0.016
Bbox1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)	0.016
Blvrb	biliverdin reductase B (flavin reductase (NADPH))	0.016
Crb3	crumbs homolog 3 (Drosophila)	0.016
Krt6b	keratin 6B	0.016
BC089597	cDNA sequence BC089597	0.016
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.016
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.016	Mouse
Adh1	alcohol dehydrogenase 1 (class I)	0.016
Orm3	orosomucoid 3	0.016
C730048C13Rik	RIKEN cDNA C730048C13 gene	0.016
Abcb7	ATP-binding cassette, sub-family B (MDR/TAP), member 7	0.015
Cyp2d12	cytochrome P450, family 2, subfamily d, polypeptide 12	0.015	Mouse
Cxcl13	chemokine (C-X-C motif) ligand 13	0.015
Rhbg	Rhesus blood group-associated B glycoprotein	0.015
Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34	0.015
Apob	apolipoprotein B	0.015
Car1	carbonic anhydrase 1	0.015
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.015
Ppl	periplakin	0.015
Kitl	kit ligand	0.015
Gsta3	glutathione S-transferase, alpha 3	0.015
Olfr2	olfactory receptor 2	0.015
C4bp	complement component 4 binding protein	0.014
2810459M11Rik	RIKEN cDNA 2810459M11 gene	0.014
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.014
Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	0.014	Mouse
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.014
Cfhr2	complement factor H-related 2	0.014
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.014
Tex12	testis expressed gene 12	0.014
Cyp3a44	cytochrome P450, family 3, subfamily a, polypeptide 44	0.014
Gm10229	predicted gene 10229	0.014
Cacna1e	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.014
Adamdec1	ADAM-like, decysin 1	0.014
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.014
Prpmp5	proline-rich protein MP5	0.014
Ces1f	carboxylesterase 1F	0.013
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.013
Uqcrfs1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.013
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.013
Fmo4	flavin containing monooxygenase 4	0.013
Mbl1	mannose-binding lectin (protein A) 1	0.013
Abcg5	ATP-binding cassette, sub-family G (WHITE), member 5	0.013
Mup4	major urinary protein 4	0.013
Prdx2	peroxiredoxin 2	0.013
Gck	glucokinase	0.013
Fut1	fucosyltransferase 1	0.013
F12	coagulation factor XII (Hageman factor)	0.013
Fam46c	family with sequence similarity 46, member C	0.013
Add1	adducin 1 (alpha)	0.013
Klkb1	kallikrein B, plasma 1	0.013
Inhbc	inhibin beta-C	0.013
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.013
F2	coagulation factor II	0.013
Hk1	hexokinase 1	0.013
Gm10228	predicted gene 10228	0.013
Bicc1	bicaudal C homolog 1 (Drosophila)	0.013
Pigq	phosphatidylinositol glycan anchor biosynthesis, class Q	0.012
Olfr49	olfactory receptor 49	0.012
Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	0.012
Hamp	hepcidin antimicrobial peptide	0.012
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.012
Steap3	STEAP family member 3	0.012
Hao1	hydroxyacid oxidase 1, liver	0.012
Mettl7b	methyltransferase like 7B	0.012
Sardh	sarcosine dehydrogenase	0.012
Iyd	iodotyrosine deiodinase	0.012
Btc	betacellulin, epidermal growth factor family member	0.012
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.012
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.012	Mouse
Hc	hemolytic complement	0.012
2810007J24Rik	RIKEN cDNA 2810007J24 gene	0.012
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.012
AB056442	cDNA sequence AB056442	0.012
Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	0.012
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.012
Clec4f	C-type lectin domain family 4, member f	0.012
Enam	enamelin	0.012
Gstm6	glutathione S-transferase, mu 6	0.012
Aadat	aminoadipate aminotransferase	0.012
Slc25a39	solute carrier family 25, member 39	0.012
Fmo2	flavin containing monooxygenase 2	0.012
Habp2	hyaluronic acid binding protein 2	0.012
Notum	notum pectinacetylesterase homolog (Drosophila)	0.011
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.011
Acsm1	acyl-CoA synthetase medium-chain family member 1	0.011
Tm4sf4	transmembrane 4 superfamily member 4	0.011
Kap	kidney androgen regulated protein	0.011
Ces1c	carboxylesterase 1C	0.011
Cyp4f15	cytochrome P450, family 4, subfamily f, polypeptide 15	0.011
Atox1	ATX1 (antioxidant protein 1) homolog 1 (yeast)	0.011
Dusp15	dual specificity phosphatase-like 15	0.011
Ces1e	carboxylesterase 1E	0.011
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.011
Aass	aminoadipate-semialdehyde synthase	0.011
Prss39	protease, serine, 39	0.011
Rhag	Rhesus blood group-associated A glycoprotein	0.011
Oprk1	opioid receptor, kappa 1	0.011
Ugt2b35	UDP glucuronosyltransferase 2 family, polypeptide B35	0.011
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.011	Mouse
1700011H14Rik	RIKEN cDNA 1700011H14 gene	0.011
D630002G06Rik	RIKEN cDNA D630002G06 gene	0.011
Abcc3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	0.011
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.011
4731417B20Rik	RIKEN cDNA 4731417B20 gene	0.011
Epas1	endothelial PAS domain protein 1	0.011
Saa4	serum amyloid A 4	0.011
Hmox1	heme oxygenase (decycling) 1	0.011
Krtap8-1	keratin associated protein 8-1	0.011
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.011
Mtnr1a	melatonin receptor 1A	0.011
Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.011
Dpys	dihydropyrimidinase	0.010
Cyp2c69	cytochrome P450, family 2, subfamily c, polypeptide 69	0.010
Serpinb11	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11	0.010
Slc6a2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.010
Nckap1l	NCK associated protein 1 like	0.010
Aldh9a1	aldehyde dehydrogenase 9, subfamily A1	0.010
Olfr140	olfactory receptor 140	0.010
Fetub	fetuin beta	0.010
Gpld1	glycosylphosphatidylinositol specific phospholipase D1	0.010
Txnrd2	thioredoxin reductase 2	0.010
Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	0.010
Canx	calnexin	0.010
Cyp2j11	cytochrome P450, family 2, subfamily j, polypeptide 11	0.010	Mouse
Creb3l3	cAMP responsive element binding protein 3-like 3	0.010