IMP

Process View

Mus musculus

4 genes annotated in mouse

Multi-species View

mitotic cell cycle arrest

GO:0071850

The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M).

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mitotic cell cycle arrest"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mitotic cell cycle arrest" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	1.000
Pten	phosphatase and tensin homolog	0.993
Mdm2	transformed mouse 3T3 cell double minute 2	0.938
Col1a1	collagen, type I, alpha 1	0.905
Rb1	retinoblastoma 1	0.888	Worm
Apc	adenomatosis polyposis coli	0.867
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.837	Human Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.628
Cdk2	cyclin-dependent kinase 2	0.552
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.422
Mdm4	transformed mouse 3T3 cell double minute 4	0.419
Brca2	breast cancer 2	0.361
Braf	Braf transforming gene	0.281
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.272
Psen1	presenilin 1	0.261
Fgfr2	fibroblast growth factor receptor 2	0.237
Ar	androgen receptor	0.220
Xpa	xeroderma pigmentosum, complementation group A	0.202
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.153
Ahr	aryl-hydrocarbon receptor	0.145
Apoe	apolipoprotein E	0.125
Foxo3	forkhead box O3	0.119
Brca1	breast cancer 1	0.109
Ccnd1	cyclin D1	0.092
Stat3	signal transducer and activator of transcription 3	0.091
Rbl1	retinoblastoma-like 1 (p107)	0.081	Worm
E2f1	E2F transcription factor 1	0.071
Ptch1	patched homolog 1	0.067
Nf1	neurofibromatosis 1	0.066
Trp63	transformation related protein 63	0.066	Mouse
Kit	kit oncogene	0.064
Trp73	transformation related protein 73	0.064	Mouse
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.060
Sox2	SRY-box containing gene 2	0.053
Emx1	empty spiracles homolog 1 (Drosophila)	0.053
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.052
Thbs1	thrombospondin 1	0.052
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.050
Emx2	empty spiracles homolog 2 (Drosophila)	0.044
Hoxa13	homeobox A13	0.040
Txndc16	thioredoxin domain containing 16	0.039
Esr1	estrogen receptor 1 (alpha)	0.039
Vhl	von Hippel-Lindau tumor suppressor	0.037
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.036
Htatip2	HIV-1 tat interactive protein 2, homolog (human)	0.036
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.036
Shh	sonic hedgehog	0.035
Rxra	retinoid X receptor alpha	0.032
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.031
Wwox	WW domain-containing oxidoreductase	0.031
Nf2	neurofibromatosis 2	0.030
Nbn	nibrin	0.029
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.029
Msh2	mutS homolog 2 (E. coli)	0.029
Stk11	serine/threonine kinase 11	0.029
Wrn	Werner syndrome homolog (human)	0.028
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.027
Klf5	Kruppel-like factor 5	0.026
Hes5	hairy and enhancer of split 5 (Drosophila)	0.025
Sfn	stratifin	0.023
Tsc1	tuberous sclerosis 1	0.023
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.023
Hif1a	hypoxia inducible factor 1, alpha subunit	0.023
Irf6	interferon regulatory factor 6	0.023
Pkdcc	protein kinase domain containing, cytoplasmic	0.022
Fgfr3	fibroblast growth factor receptor 3	0.022
Skil	SKI-like	0.020
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.019
Kitl	kit ligand	0.019
Pinx1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.018
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.018
Casp3	caspase 3	0.018
Ccne2	cyclin E2	0.018	Worm
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.017
Fgf9	fibroblast growth factor 9	0.016
Bcl2	B-cell leukemia/lymphoma 2	0.016
Prlr	prolactin receptor	0.015
Gen1	Gen homolog 1, endonuclease (Drosophila)	0.015
Zeb1	zinc finger E-box binding homeobox 1	0.015
Pparg	peroxisome proliferator activated receptor gamma	0.015
Atm	ataxia telangiectasia mutated homolog (human)	0.015
Sox9	SRY-box containing gene 9	0.015
Chd7	chromodomain helicase DNA binding protein 7	0.015
Ccne1	cyclin E1	0.014	Worm
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.014
Runx1	runt related transcription factor 1	0.013
Meox2	mesenchyme homeobox 2	0.013
Tgfb1	transforming growth factor, beta 1	0.013
Ep300	E1A binding protein p300	0.012
Hes1	hairy and enhancer of split 1 (Drosophila)	0.012
Huwe1	HECT, UBA and WWE domain containing 1	0.012
Cenpf	centromere protein F	0.012
Yap1	yes-associated protein 1	0.011
Apaf1	apoptotic peptidase activating factor 1	0.011
Myc	myelocytomatosis oncogene	0.011
Smad3	MAD homolog 3 (Drosophila)	0.011
Terf1	telomeric repeat binding factor 1	0.011
Hoxa10	homeobox A10	0.010
Psap	prosaposin	0.010
Ptgs2	prostaglandin-endoperoxide synthase 2	0.010
Cenpl	centromere protein L	0.010
Ikzf1	IKAROS family zinc finger 1	0.010
Men1	multiple endocrine neoplasia 1	0.010
Mapk8	mitogen-activated protein kinase 8	0.010
Lin9	lin-9 homolog (C. elegans)	0.010
Cdk6	cyclin-dependent kinase 6	0.010