IMP

Process View

Mus musculus

2 genes annotated in mouse

postganglionic parasympathetic nervous system development

The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "postganglionic parasympathetic nervous system development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "postganglionic parasympathetic nervous system development" (in gray)

Name	Description	Probability	Func Analog Organism
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.998
Ret	ret proto-oncogene	0.992
Nrp1	neuropilin 1	0.960
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.949
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.944
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.908
Lama5	laminin, alpha 5	0.899
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.748
Vegfa	vascular endothelial growth factor A	0.681
Epha4	Eph receptor A4	0.504
Gpr27	G protein-coupled receptor 27	0.474
Plxna1	plexin A1	0.413	Mouse
Rara	retinoic acid receptor, alpha	0.406
Sdc3	syndecan 3	0.360
Ednra	endothelin receptor type A	0.352
Wnt6	wingless-related MMTV integration site 6	0.318
Rarg	retinoic acid receptor, gamma	0.259
Bcl2	B-cell leukemia/lymphoma 2	0.244
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.212
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.192
Sox10	SRY-box containing gene 10	0.184
Nynrin	NYN domain and retroviral integrase containing	0.182
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.181
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.174
Ephb2	Eph receptor B2	0.167
Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.156
Wnt7b	wingless-related MMTV integration site 7B	0.142
Phox2a	paired-like homeobox 2a	0.136
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.135
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.135
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.130
Efna2	ephrin A2	0.126
Nrtn	neurturin	0.121	Mouse
Crlf1	cytokine receptor-like factor 1	0.119
Matn4	matrilin 4	0.114
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.112
Phox2b	paired-like homeobox 2b	0.108
Nrp2	neuropilin 2	0.106
Isl1	ISL1 transcription factor, LIM/homeodomain	0.105
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.104
Nog	noggin	0.096
Pax2	paired box gene 2	0.092
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.088
Plxnb1	plexin B1	0.087	Mouse
Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.083
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.082
Foxd2	forkhead box D2	0.080
Wnt4	wingless-related MMTV integration site 4	0.078
Rgnef	Rho-guanine nucleotide exchange factor	0.073
Tlx2	T-cell leukemia, homeobox 2	0.071
Nos1	nitric oxide synthase 1, neuronal	0.070
Tbx1	T-box 1	0.068
Lrfn1	leucine rich repeat and fibronectin type III domain containing 1	0.058
H1fx	H1 histone family, member X	0.055
Rarb	retinoic acid receptor, beta	0.055
Gdnf	glial cell line derived neurotrophic factor	0.052
Wnt2b	wingless related MMTV integration site 2b	0.052
Sox4	SRY-box containing gene 4	0.050
Lamc1	laminin, gamma 1	0.050
Rnf208	ring finger protein 208	0.049
Pbx1	pre B-cell leukemia transcription factor 1	0.049
Ephb3	Eph receptor B3	0.047
Cdk14	cyclin-dependent kinase 14	0.047
Grik5	glutamate receptor, ionotropic, kainate 5 (gamma 2)	0.042
Fzd8	frizzled homolog 8 (Drosophila)	0.042
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.041
Mkl2	MKL/myocardin-like 2	0.041
Tspan9	tetraspanin 9	0.039
Dnahc1	dynein, axonemal, heavy chain 1	0.038
Aatk	apoptosis-associated tyrosine kinase	0.038
Apln	apelin	0.037
Axin2	axin2	0.037
Kit	kit oncogene	0.037
Grb10	growth factor receptor bound protein 10	0.037
Rxra	retinoid X receptor alpha	0.036
Tcfap2a	transcription factor AP-2, alpha	0.036
Gata4	GATA binding protein 4	0.036
Bmp7	bone morphogenetic protein 7	0.035
Bnc1	basonuclin 1	0.034
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.034
Ccdc24	coiled-coil domain containing 24	0.033
Zfp651	zinc finger protein 651	0.033
Trim46	tripartite motif-containing 46	0.033
Sim2	single-minded homolog 2 (Drosophila)	0.033
Zp1	zona pellucida glycoprotein 1	0.033
Cul7	cullin 7	0.032
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.032
Wnt9a	wingless-type MMTV integration site 9A	0.032
Zfp358	zinc finger protein 358	0.032
Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.032
Chrd	chordin	0.032
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.031
Src	Rous sarcoma oncogene	0.031
Ebf3	early B-cell factor 3	0.031
Phldb1	pleckstrin homology-like domain, family B, member 1	0.030
Abca2	ATP-binding cassette, sub-family A (ABC1), member 2	0.030
Tgif2	TGFB-induced factor homeobox 2	0.030
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.029
Efnb2	ephrin B2	0.029
Mybpc3	myosin binding protein C, cardiac	0.029
Vhl	von Hippel-Lindau tumor suppressor	0.029
Nos3	nitric oxide synthase 3, endothelial cell	0.029
Efna5	ephrin A5	0.028
Pou3f1	POU domain, class 3, transcription factor 1	0.028
Ank1	ankyrin 1, erythroid	0.028
Sult4a1	sulfotransferase family 4A, member 1	0.028
Dlk1	delta-like 1 homolog (Drosophila)	0.027
Leprel2	leprecan-like 2	0.027
Krtap5-1	keratin associated protein 5-1	0.027
Zfr2	zinc finger RNA binding protein 2	0.026
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.026
Tnni1	troponin I, skeletal, slow 1	0.026
Ece1	endothelin converting enzyme 1	0.025
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.025
Pld2	phospholipase D2	0.025
Twist2	twist homolog 2 (Drosophila)	0.025
Inha	inhibin alpha	0.025
Lhx1	LIM homeobox protein 1	0.025
Scn5a	sodium channel, voltage-gated, type V, alpha	0.025
Adam11	a disintegrin and metallopeptidase domain 11	0.025
Cacng7	calcium channel, voltage-dependent, gamma subunit 7	0.025
Vax1	ventral anterior homeobox containing gene 1	0.024
Unc5c	unc-5 homolog C (C. elegans)	0.024
Ubtd1	ubiquitin domain containing 1	0.024
Lef1	lymphoid enhancer binding factor 1	0.024
Ncs1	neuronal calcium sensor 1	0.024
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.023
Dpysl2	dihydropyrimidinase-like 2	0.022
Cdsn	corneodesmosin	0.022
Grid1	glutamate receptor, ionotropic, delta 1	0.022
Extl3	exostoses (multiple)-like 3	0.022
Lamc3	laminin gamma 3	0.022
Nt5e	5' nucleotidase, ecto	0.022
Cd151	CD151 antigen	0.022
Flt1	FMS-like tyrosine kinase 1	0.021
Zbtb46	zinc finger and BTB domain containing 46	0.021
Slc22a17	solute carrier family 22 (organic cation transporter), member 17	0.021
Srgap1	SLIT-ROBO Rho GTPase activating protein 1	0.021
Fgf8	fibroblast growth factor 8	0.021
Smad3	MAD homolog 3 (Drosophila)	0.021
Irx5	Iroquois related homeobox 5 (Drosophila)	0.021
Psca	prostate stem cell antigen	0.021
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.021
Timp2	tissue inhibitor of metalloproteinase 2	0.021
Adamts7	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7	0.021
Efnb1	ephrin B1	0.020
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.020
Obsl1	obscurin-like 1	0.020
Mtl5	metallothionein-like 5, testis-specific (tesmin)	0.020
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.020
Hcn3	hyperpolarization-activated, cyclic nucleotide-gated K+ 3	0.020
Lhb	luteinizing hormone beta	0.020
Col7a1	collagen, type VII, alpha 1	0.020
Hif3a	hypoxia inducible factor 3, alpha subunit	0.019
Sox11	SRY-box containing gene 11	0.019
Fn1	fibronectin 1	0.019
Mmp15	matrix metallopeptidase 15	0.019
Pkp1	plakophilin 1	0.019
Foxj1	forkhead box J1	0.019
Nfia	nuclear factor I/A	0.018
Efs	embryonal Fyn-associated substrate	0.018
Scx	scleraxis	0.018
Plxna3	plexin A3	0.018	Mouse
Krt86	keratin 86	0.018
Gli3	GLI-Kruppel family member GLI3	0.018
Des	desmin	0.018
Wnt9b	wingless-type MMTV integration site 9B	0.018
Ptpru	protein tyrosine phosphatase, receptor type, U	0.018
B4galt2	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2	0.018
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.018
Pou3f2	POU domain, class 3, transcription factor 2	0.018
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.018
Ier5l	immediate early response 5-like	0.018
Fosl2	fos-like antigen 2	0.018
Llgl1	lethal giant larvae homolog 1 (Drosophila)	0.018
Slc27a3	solute carrier family 27 (fatty acid transporter), member 3	0.017
Akt3	thymoma viral proto-oncogene 3	0.017
Alk	anaplastic lymphoma kinase	0.017
Irx3	Iroquois related homeobox 3 (Drosophila)	0.017
Acvr1	activin A receptor, type 1	0.017
Mrc2	mannose receptor, C type 2	0.017
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.017
Neo1	neogenin	0.017
Notch3	Notch gene homolog 3 (Drosophila)	0.017
Chst3	carbohydrate (chondroitin 6/keratan) sulfotransferase 3	0.017
Nrg1	neuregulin 1	0.017
Capn5	calpain 5	0.017
Fstl3	follistatin-like 3	0.017
Wnt10b	wingless related MMTV integration site 10b	0.016
Plxnb3	plexin B3	0.016	Mouse
Tbx2	T-box 2	0.016
Itga3	integrin alpha 3	0.016
Wrn	Werner syndrome homolog (human)	0.016
Ntf3	neurotrophin 3	0.016
Klf7	Kruppel-like factor 7 (ubiquitous)	0.015
Pea15a	phosphoprotein enriched in astrocytes 15A	0.015
Foxn4	forkhead box N4	0.015
Ptk7	PTK7 protein tyrosine kinase 7	0.015
Atp13a2	ATPase type 13A2	0.015
Kdr	kinase insert domain protein receptor	0.015
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.015
Glis1	GLIS family zinc finger 1	0.015
Odf3	outer dense fiber of sperm tails 3	0.015
Ltbp1	latent transforming growth factor beta binding protein 1	0.015
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.015
Hoxa3	homeobox A3	0.015
Ptgds	prostaglandin D2 synthase (brain)	0.015
Bmp1	bone morphogenetic protein 1	0.014
Cd177	CD177 antigen	0.014
Calcb	calcitonin-related polypeptide, beta	0.014
Fam83g	family with sequence similarity 83, member G	0.014
Nckap5l	NCK-associated protein 5-like	0.014
Polm	polymerase (DNA directed), mu	0.014
Hip1	huntingtin interacting protein 1	0.014
Wt1	Wilms tumor 1 homolog	0.014
Ephb6	Eph receptor B6	0.014
Ankrd11	ankyrin repeat domain 11	0.014
Dchs1	dachsous 1 (Drosophila)	0.014
Evpl	envoplakin	0.014
Fam20c	family with sequence similarity 20, member C	0.014
Wnt10a	wingless related MMTV integration site 10a	0.014
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.014
Kirrel2	kin of IRRE like 2 (Drosophila)	0.014
Rtkn	rhotekin	0.014
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.014
Nav1	neuron navigator 1	0.013
Klf3	Kruppel-like factor 3 (basic)	0.013
Zfp518b	zinc finger protein 518B	0.013
Hoxa4	homeobox A4	0.013
Smo	smoothened homolog (Drosophila)	0.013
Gal	galanin	0.013
Slc25a29	solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29	0.013
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.013
Sorcs2	sortilin-related VPS10 domain containing receptor 2	0.013
Fzd1	frizzled homolog 1 (Drosophila)	0.013
Otog	otogelin	0.013
Zfp703	zinc finger protein 703	0.013
Mzf1	myeloid zinc finger 1	0.013
Snai1	snail homolog 1 (Drosophila)	0.013
Hr	hairless	0.013
Cbln1	cerebellin 1 precursor protein	0.013
Sdk2	sidekick homolog 2 (chicken)	0.013
Sftpb	surfactant associated protein B	0.013
Pdgfb	platelet derived growth factor, B polypeptide	0.013
Ebf4	early B-cell factor 4	0.013
Dock4	dedicator of cytokinesis 4	0.013
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.013
Dapk1	death associated protein kinase 1	0.013
Epn3	epsin 3	0.013
Zfp316	zinc finger protein 316	0.013
Ednrb	endothelin receptor type B	0.013
Rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.013
Diras1	DIRAS family, GTP-binding RAS-like 1	0.013
Itpk1	inositol 1,3,4-triphosphate 5/6 kinase	0.012
Nxnl2	nucleoredoxin-like 2	0.012
Ly6h	lymphocyte antigen 6 complex, locus H	0.012
Rapsn	receptor-associated protein of the synapse	0.012
Ikzf4	IKAROS family zinc finger 4	0.012
Igsf9	immunoglobulin superfamily, member 9	0.012
Rsph1	radial spoke head 1 homolog (Chlamydomonas)	0.012
Lrp1	low density lipoprotein receptor-related protein 1	0.012
Angpt4	angiopoietin 4	0.012
Ncoa2	nuclear receptor coactivator 2	0.012
Fjx1	four jointed box 1 (Drosophila)	0.012
Pknox2	Pbx/knotted 1 homeobox 2	0.012
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.012
Greb1	gene regulated by estrogen in breast cancer protein	0.012
Sobp	sine oculis-binding protein homolog (Drosophila)	0.012
Prrc2b	proline-rich coiled-coil 2B	0.011
Pou3f3	POU domain, class 3, transcription factor 3	0.011
Agrn	agrin	0.011
Tmem200b	transmembrane protein 200B	0.011
Zcchc14	zinc finger, CCHC domain containing 14	0.011
Pvrl2	poliovirus receptor-related 2	0.011
Apc2	adenomatosis polyposis coli 2	0.011
Meox1	mesenchyme homeobox 1	0.011
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.011
Epas1	endothelial PAS domain protein 1	0.011
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.011
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.011
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.011
Artn	artemin	0.011	Mouse
Mmp11	matrix metallopeptidase 11	0.011
Tff1	trefoil factor 1	0.011
Fbn2	fibrillin 2	0.011
Ilk	integrin linked kinase	0.011
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.011
Nptx1	neuronal pentraxin 1	0.011
Arhgap8	Rho GTPase activating protein 8	0.011
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.011
Usp22	ubiquitin specific peptidase 22	0.011
Asb10	ankyrin repeat and SOCS box-containing 10	0.011
Cdc42bpa	CDC42 binding protein kinase alpha	0.011
Synj2	synaptojanin 2	0.011
Hic1	hypermethylated in cancer 1	0.010
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.010
Papln	papilin, proteoglycan-like sulfated glycoprotein	0.010
Dll3	delta-like 3 (Drosophila)	0.010
Prrx2	paired related homeobox 2	0.010
Wnt5b	wingless-related MMTV integration site 5B	0.010
Gpr56	G protein-coupled receptor 56	0.010
Cldn27	claudin 27	0.010
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.010
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.010
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.010
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.010
S1pr3	sphingosine-1-phosphate receptor 3	0.010
Inhbb	inhibin beta-B	0.010
Slc38a8	solute carrier family 38, member 8	0.010