IMP

Process View

Mus musculus

1 genes annotated in mouse

pulmonary valve formation

The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "pulmonary valve formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "pulmonary valve formation" (in gray)

Name	Description	Probability	Func Analog Organism
Pitx2	paired-like homeodomain transcription factor 2	0.989
Shh	sonic hedgehog	0.959
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.959
Fgfr2	fibroblast growth factor receptor 2	0.954
Pitx1	paired-like homeodomain transcription factor 1	0.914
Tbx3	T-box 3	0.892	Mouse
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.889
Pax2	paired box gene 2	0.887
Foxg1	forkhead box G1	0.800
Scn5a	sodium channel, voltage-gated, type V, alpha	0.780
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.779
Hoxa1	homeobox A1	0.745
Prrx1	paired related homeobox 1	0.581
Eya1	eyes absent 1 homolog (Drosophila)	0.523
Tbx1	T-box 1	0.482	Mouse
Efnb2	ephrin B2	0.469
Hand2	heart and neural crest derivatives expressed transcript 2	0.444
Chd7	chromodomain helicase DNA binding protein 7	0.434
Gli3	GLI-Kruppel family member GLI3	0.409
Msx1	homeobox, msh-like 1	0.402
Tcfap2a	transcription factor AP-2, alpha	0.397
Gja5	gap junction protein, alpha 5	0.394
Bmp4	bone morphogenetic protein 4	0.387
Tbx4	T-box 4	0.337	Mouse
Sox2	SRY-box containing gene 2	0.317
Jag1	jagged 1	0.312
Foxc2	forkhead box C2	0.310
Fgf10	fibroblast growth factor 10	0.307
Hand1	heart and neural crest derivatives expressed transcript 1	0.301
Pax3	paired box gene 3	0.298
Otx2	orthodenticle homolog 2 (Drosophila)	0.275
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.269
Zic3	zinc finger protein of the cerebellum 3	0.242
Vangl2	vang-like 2 (van gogh, Drosophila)	0.225
Tbx5	T-box 5	0.213	Mouse
Sox9	SRY-box containing gene 9	0.205
Foxc1	forkhead box C1	0.200
Fgfr3	fibroblast growth factor receptor 3	0.192
Lrp6	low density lipoprotein receptor-related protein 6	0.181
Dlx5	distal-less homeobox 5	0.180
Ighmbp2	immunoglobulin mu binding protein 2	0.180
Sall4	sal-like 4 (Drosophila)	0.180
Lef1	lymphoid enhancer binding factor 1	0.173
Fgf8	fibroblast growth factor 8	0.165
Runx2	runt related transcription factor 2	0.165
Zeb1	zinc finger E-box binding homeobox 1	0.152
Alx1	ALX homeobox 1	0.130
Emx1	empty spiracles homolog 1 (Drosophila)	0.115
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.104
Bdnf	brain derived neurotrophic factor	0.101
Hoxa3	homeobox A3	0.091
Wt1	Wilms tumor 1 homolog	0.082
Gsc	goosecoid homeobox	0.080
Gata3	GATA binding protein 3	0.078
Lmx1a	LIM homeobox transcription factor 1 alpha	0.078
Gbx2	gastrulation brain homeobox 2	0.076
Smad6	MAD homolog 6 (Drosophila)	0.075
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.072
Dll4	delta-like 4 (Drosophila)	0.070
Msx2	homeobox, msh-like 2	0.068
Gata4	GATA binding protein 4	0.066
Pou5f1	POU domain, class 5, transcription factor 1	0.063
Lrp5	low density lipoprotein receptor-related protein 5	0.063
Hoxa13	homeobox A13	0.060
Nanog	Nanog homeobox	0.058
Irx3	Iroquois related homeobox 3 (Drosophila)	0.057
Bmp5	bone morphogenetic protein 5	0.056
Gata6	GATA binding protein 6	0.054
Hmx3	H6 homeobox 3	0.051
Pax9	paired box gene 9	0.049
Chrd	chordin	0.047
Tcf21	transcription factor 21	0.046
Tcfcp2l1	transcription factor CP2-like 1	0.046
Rnf2	ring finger protein 2	0.045
Alx3	aristaless-like homeobox 3	0.044
Shox2	short stature homeobox 2	0.044
Dlx2	distal-less homeobox 2	0.042
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.041
Prrx2	paired related homeobox 2	0.040
Myf5	myogenic factor 5	0.040
Mn1	meningioma 1	0.039
Trp63	transformation related protein 63	0.038
Hoxa10	homeobox A10	0.038
Noto	notochord homolog (Xenopus laevis)	0.038
Myo7a	myosin VIIA	0.035
Col13a1	collagen, type XIII, alpha 1	0.033
Otx1	orthodenticle homolog 1 (Drosophila)	0.033
Prdm6	PR domain containing 6	0.032
Bmp7	bone morphogenetic protein 7	0.031
Twist2	twist homolog 2 (Drosophila)	0.030
Isl1	ISL1 transcription factor, LIM/homeodomain	0.030
Wnt3a	wingless-related MMTV integration site 3A	0.029
Wnt5a	wingless-related MMTV integration site 5A	0.029
Sall1	sal-like 1 (Drosophila)	0.028
Cxadr	coxsackie virus and adenovirus receptor	0.028
Hoxa2	homeobox A2	0.027
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.026
Smo	smoothened homolog (Drosophila)	0.026
Myl3	myosin, light polypeptide 3	0.025
Sox11	SRY-box containing gene 11	0.025
Nog	noggin	0.024
Gata5	GATA binding protein 5	0.024
Hmx2	H6 homeobox 2	0.024
Gdnf	glial cell line derived neurotrophic factor	0.024
Gata2	GATA binding protein 2	0.023
Fgfr1	fibroblast growth factor receptor 1	0.023
Cd8b1	CD8 antigen, beta chain 1	0.023
T	brachyury	0.022	Mouse
Gli2	GLI-Kruppel family member GLI2	0.022
Tcfap2c	transcription factor AP-2, gamma	0.021
Fev	FEV (ETS oncogene family)	0.020
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.020
Bnc1	basonuclin 1	0.019
Ryr2	ryanodine receptor 2, cardiac	0.019
Hoxd1	homeobox D1	0.019
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.019
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.018
Irx4	Iroquois related homeobox 4 (Drosophila)	0.018
Foxf1a	forkhead box F1a	0.018
Ptk7	PTK7 protein tyrosine kinase 7	0.018
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.017
Asb10	ankyrin repeat and SOCS box-containing 10	0.017
Hoxa4	homeobox A4	0.017
Tbx20	T-box 20	0.017
Vegfa	vascular endothelial growth factor A	0.017
Fgf3	fibroblast growth factor 3	0.017
Mecom	MDS1 and EVI1 complex locus	0.017
Lhx9	LIM homeobox protein 9	0.017
Xirp1	xin actin-binding repeat containing 1	0.016
Hoxa11	homeobox A11	0.016
En1	engrailed 1	0.016
S1pr4	sphingosine-1-phosphate receptor 4	0.016
Rxra	retinoid X receptor alpha	0.016
Tgfb2	transforming growth factor, beta 2	0.015
Kremen1	kringle containing transmembrane protein 1	0.015
Bmp2	bone morphogenetic protein 2	0.015
Atoh8	atonal homolog 8 (Drosophila)	0.015
Pax7	paired box gene 7	0.015
Pou4f2	POU domain, class 4, transcription factor 2	0.015
Msc	musculin	0.015
Asb12	ankyrin repeat and SOCS box-containing 12	0.015
Pou4f3	POU domain, class 4, transcription factor 3	0.014
Hoxd8	homeobox D8	0.014
Tlx3	T-cell leukemia, homeobox 3	0.014
Npr3	natriuretic peptide receptor 3	0.014
Foxf2	forkhead box F2	0.014
Vstm2b	V-set and transmembrane domain containing 2B	0.014
Fgf18	fibroblast growth factor 18	0.014
Tnfrsf25	tumor necrosis factor receptor superfamily, member 25	0.013
Emid2	EMI domain containing 2	0.013
Pbx1	pre B-cell leukemia transcription factor 1	0.013
Dlx6	distal-less homeobox 6	0.013
Sox17	SRY-box containing gene 17	0.013
Hoxc8	homeobox C8	0.013
Ntf3	neurotrophin 3	0.013
Foxa1	forkhead box A1	0.013
Snai1	snail homolog 1 (Drosophila)	0.013
Hoxd9	homeobox D9	0.013
Hmga2	high mobility group AT-hook 2	0.013
Osr1	odd-skipped related 1 (Drosophila)	0.013
Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	0.013
Rybp	RING1 and YY1 binding protein	0.013
Nckap5l	NCK-associated protein 5-like	0.013
Mnx1	motor neuron and pancreas homeobox 1	0.012
Zic1	zinc finger protein of the cerebellum 1	0.012
Socs1	suppressor of cytokine signaling 1	0.012
Alx4	aristaless-like homeobox 4	0.012
Cd274	CD274 antigen	0.012
Hoxd11	homeobox D11	0.012
BC020535	cDNA sequence BC020535	0.012
Tal1	T-cell acute lymphocytic leukemia 1	0.012
Tbx2	T-box 2	0.012	Mouse
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.012
Irx5	Iroquois related homeobox 5 (Drosophila)	0.012
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.012
Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	0.012
Foxb1	forkhead box B1	0.012
Nkx3-2	NK3 homeobox 2	0.012
Xrn1	5'-3' exoribonuclease 1	0.011
Nkx2-1	NK2 homeobox 1	0.011
Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	0.011
Pcdh12	protocadherin 12	0.011
Sox7	SRY-box containing gene 7	0.011
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.011
Notch1	Notch gene homolog 1 (Drosophila)	0.011
Sp8	trans-acting transcription factor 8	0.011
Ptch1	patched homolog 1	0.011
Sim2	single-minded homolog 2 (Drosophila)	0.011
Zfpm2	zinc finger protein, multitype 2	0.011
Robo4	roundabout homolog 4 (Drosophila)	0.011
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.011
Myf6	myogenic factor 6	0.011
Satb2	special AT-rich sequence binding protein 2	0.011
Nkd2	naked cuticle 2 homolog (Drosophila)	0.011
Egfr	epidermal growth factor receptor	0.011
Eya4	eyes absent 4 homolog (Drosophila)	0.011
Klf14	Kruppel-like factor 14	0.011
Emx2	empty spiracles homolog 2 (Drosophila)	0.011
Hoxd13	homeobox D13	0.011
Myl7	myosin, light polypeptide 7, regulatory	0.011
Hoxb4	homeobox B4	0.011
Thsd1	thrombospondin, type I, domain 1	0.010
Dlx1	distal-less homeobox 1	0.010
Ushbp1	Usher syndrome 1C binding protein 1	0.010
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.010
Pikfyve	phosphoinositide kinase, FYVE finger containing	0.010
Cbx8	chromobox homolog 8 (Drosophila Pc class)	0.010
Axin2	axin2	0.010