IMP

Process View

Mus musculus

14 genes annotated in mouse

kidney mesenchyme development

GO:0072074

The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "kidney mesenchyme development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "kidney mesenchyme development" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	0.978
Shh	sonic hedgehog	0.965
Tbx1	T-box 1	0.962
Fgfr2	fibroblast growth factor receptor 2	0.917
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.788
Foxa2	forkhead box A2	0.783	Mouse
Tcf21	transcription factor 21	0.752
Foxh1	forkhead box H1	0.723
Msx1	homeobox, msh-like 1	0.698
Fgf8	fibroblast growth factor 8	0.663
Pax8	paired box gene 8	0.626	Mouse
Eya1	eyes absent 1 homolog (Drosophila)	0.623
Bmp4	bone morphogenetic protein 4	0.594
Hand2	heart and neural crest derivatives expressed transcript 2	0.572
Hand1	heart and neural crest derivatives expressed transcript 1	0.571
Gli3	GLI-Kruppel family member GLI3	0.535
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.523
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.507
Pbx1	pre B-cell leukemia transcription factor 1	0.484
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.470
Ctnnb1	catenin (cadherin associated protein), beta 1	0.467
Prrx2	paired related homeobox 2	0.454
Otx2	orthodenticle homolog 2 (Drosophila)	0.434
Lhx1	LIM homeobox protein 1	0.431
Emx2	empty spiracles homolog 2 (Drosophila)	0.425
Lmx1a	LIM homeobox transcription factor 1 alpha	0.407
Gata4	GATA binding protein 4	0.373
Gas1	growth arrest specific 1	0.365
Ptch1	patched homolog 1	0.355
Gsc	goosecoid homeobox	0.311
Hoxd13	homeobox D13	0.308
Hoxd11	homeobox D11	0.305
Foxc1	forkhead box C1	0.296	Mouse
Hoxd3	homeobox D3	0.288
Nodal	nodal	0.287	Mouse
Wt1	Wilms tumor 1 homolog	0.285
Prrx1	paired related homeobox 1	0.257
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.240
Gbx2	gastrulation brain homeobox 2	0.226
Pitx2	paired-like homeodomain transcription factor 2	0.221
Smad3	MAD homolog 3 (Drosophila)	0.209	Mouse
Nkx2-1	NK2 homeobox 1	0.205
Pax3	paired box gene 3	0.205
Fgfr3	fibroblast growth factor receptor 3	0.188
Rarb	retinoic acid receptor, beta	0.181
Hoxa2	homeobox A2	0.176
Alx4	aristaless-like homeobox 4	0.175
Apc	adenomatosis polyposis coli	0.167
Gata6	GATA binding protein 6	0.163
Tbx2	T-box 2	0.161
Hoxa11	homeobox A11	0.161
Meox2	mesenchyme homeobox 2	0.160
Bnc1	basonuclin 1	0.160
Nog	noggin	0.153
Vax1	ventral anterior homeobox containing gene 1	0.143
Hmx1	H6 homeobox 1	0.142
Msx2	homeobox, msh-like 2	0.138
Tbx15	T-box 15	0.138
Fgfr1	fibroblast growth factor receptor 1	0.135
Hoxa1	homeobox A1	0.133
Hmx3	H6 homeobox 3	0.128
Pax9	paired box gene 9	0.126	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.121	Mouse
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.119
Dlx5	distal-less homeobox 5	0.106
Smo	smoothened homolog (Drosophila)	0.106
Gdnf	glial cell line derived neurotrophic factor	0.105
Fgf3	fibroblast growth factor 3	0.104
Tgfb2	transforming growth factor, beta 2	0.103
Gdf5	growth differentiation factor 5	0.096	Mouse
Foxc2	forkhead box C2	0.096	Mouse
Lef1	lymphoid enhancer binding factor 1	0.095
Acvr1	activin A receptor, type 1	0.091
Gli2	GLI-Kruppel family member GLI2	0.091
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.087	Mouse
Adra2b	adrenergic receptor, alpha 2b	0.083
Wnt3a	wingless-related MMTV integration site 3A	0.081
Foxd2	forkhead box D2	0.077	Mouse
Zic3	zinc finger protein of the cerebellum 3	0.077
Nab2	Ngfi-A binding protein 2	0.076
Tcfap2a	transcription factor AP-2, alpha	0.071
Smad1	MAD homolog 1 (Drosophila)	0.067	Mouse
Tlx2	T-cell leukemia, homeobox 2	0.067
Foxa1	forkhead box A1	0.066	Mouse
Bcl2	B-cell leukemia/lymphoma 2	0.066
Hoxa9	homeobox A9	0.065
En1	engrailed 1	0.064
Cdx1	caudal type homeobox 1	0.064
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.064
Pitx3	paired-like homeodomain transcription factor 3	0.064
Bmp7	bone morphogenetic protein 7	0.062
Hes1	hairy and enhancer of split 1 (Drosophila)	0.059
Gdf6	growth differentiation factor 6	0.059	Mouse
Fos	FBJ osteosarcoma oncogene	0.056
T	brachyury	0.055
Wnt6	wingless-related MMTV integration site 6	0.054
Lhx9	LIM homeobox protein 9	0.054
Rarg	retinoic acid receptor, gamma	0.052
Sox7	SRY-box containing gene 7	0.052
Hoxd9	homeobox D9	0.051
Vangl2	vang-like 2 (van gogh, Drosophila)	0.049
Otx1	orthodenticle homolog 1 (Drosophila)	0.049
Axin1	axin 1	0.047
Wnt2b	wingless related MMTV integration site 2b	0.047
Erbb2ip	Erbb2 interacting protein	0.044
Jun	Jun oncogene	0.043
Amhr2	anti-Mullerian hormone type 2 receptor	0.042
Twist1	twist homolog 1 (Drosophila)	0.041
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.041
Npr3	natriuretic peptide receptor 3	0.041
Neurog1	neurogenin 1	0.039
Gdf3	growth differentiation factor 3	0.039	Mouse
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.038
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.037
Ihh	Indian hedgehog	0.035	Mouse
Jag1	jagged 1	0.035
Pthlh	parathyroid hormone-like peptide	0.035
Barx1	BarH-like homeobox 1	0.035
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.034
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.034
Hoxb6	homeobox B6	0.034
Wnt1	wingless-related MMTV integration site 1	0.034
Zfp503	zinc finger protein 503	0.034
Socs1	suppressor of cytokine signaling 1	0.032
Gpc3	glypican 3	0.032
Myod1	myogenic differentiation 1	0.031
Gdf1	growth differentiation factor 1	0.031	Mouse
Uncx	UNC homeobox	0.031
Osr1	odd-skipped related 1 (Drosophila)	0.030
Foxd3	forkhead box D3	0.030	Mouse
Hmx2	H6 homeobox 2	0.029
Amh	anti-Mullerian hormone	0.029
Hoxa4	homeobox A4	0.029
Eya4	eyes absent 4 homolog (Drosophila)	0.028
Runx2	runt related transcription factor 2	0.028
Tead3	TEA domain family member 3	0.028
Matn3	matrilin 3	0.027
Tbx3	T-box 3	0.026
Tbx10	T-box 10	0.026
Twist2	twist homolog 2 (Drosophila)	0.026
Emid2	EMI domain containing 2	0.026
Evx2	even skipped homeotic gene 2 homolog	0.025
Evx1	even skipped homeotic gene 1 homolog	0.025
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.025
Fbln1	fibulin 1	0.024
Hoxa5	homeobox A5	0.024
Lrp2	low density lipoprotein receptor-related protein 2	0.024
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.024
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.024
Wnt10b	wingless related MMTV integration site 10b	0.024
Efna2	ephrin A2	0.023
Foxf1a	forkhead box F1a	0.023
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.023
Bmp2	bone morphogenetic protein 2	0.023	Mouse
Gja3	gap junction protein, alpha 3	0.023
Hoxc8	homeobox C8	0.022
Col2a1	collagen, type II, alpha 1	0.022
Rem1	rad and gem related GTP binding protein 1	0.022
Lrp6	low density lipoprotein receptor-related protein 6	0.022
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.022
Hoxa10	homeobox A10	0.022
Efna4	ephrin A4	0.022
Rax	retina and anterior neural fold homeobox	0.021
Cldn3	claudin 3	0.021
Dlx2	distal-less homeobox 2	0.021
Fgf15	fibroblast growth factor 15	0.021
Hoxb1	homeobox B1	0.021
Fzd8	frizzled homolog 8 (Drosophila)	0.021
Tgfbr2	transforming growth factor, beta receptor II	0.021
Ptk7	PTK7 protein tyrosine kinase 7	0.020
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.020
Hoxa13	homeobox A13	0.020
Dmrt3	doublesex and mab-3 related transcription factor 3	0.020
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.020
Sox3	SRY-box containing gene 3	0.019
Figla	folliculogenesis specific basic helix-loop-helix	0.019
Wnt3	wingless-related MMTV integration site 3	0.019
Fgf18	fibroblast growth factor 18	0.018
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.018
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.018	Mouse
Col13a1	collagen, type XIII, alpha 1	0.018
Ntf3	neurotrophin 3	0.018
Hoxb3	homeobox B3	0.017
BC057022	cDNA sequence BC057022	0.017
Isl1	ISL1 transcription factor, LIM/homeodomain	0.017
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.017
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.017
Otp	orthopedia homolog (Drosophila)	0.016
Hoxc4	homeobox C4	0.016
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.016
Hoxd4	homeobox D4	0.016
Etv2	ets variant gene 2	0.016
Nkx3-2	NK3 homeobox 2	0.016
Hoxd10	homeobox D10	0.016
Pax7	paired box gene 7	0.016
Pou4f3	POU domain, class 4, transcription factor 3	0.016
Hnf1b	HNF1 homeobox B	0.016
She	src homology 2 domain-containing transforming protein E	0.015
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.015
Gata3	GATA binding protein 3	0.015
Foxb1	forkhead box B1	0.015
Foxf2	forkhead box F2	0.015
Tcl1	T-cell lymphoma breakpoint 1	0.015
Bicc1	bicaudal C homolog 1 (Drosophila)	0.015
Sox2	SRY-box containing gene 2	0.015
Elf3	E74-like factor 3	0.015
Gli1	GLI-Kruppel family member GLI1	0.014
Zfp362	zinc finger protein 362	0.014
Hoxb9	homeobox B9	0.014
Smad7	MAD homolog 7 (Drosophila)	0.014	Mouse
Hoxb13	homeobox B13	0.014
Ar	androgen receptor	0.014
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.014	Mouse
Ptgs2	prostaglandin-endoperoxide synthase 2	0.014
Meis2	Meis homeobox 2	0.014
Sox17	SRY-box containing gene 17	0.014
Wnt9b	wingless-type MMTV integration site 9B	0.014
Cys1	cystin 1	0.014
Wnt5a	wingless-related MMTV integration site 5A	0.014
Ptch2	patched homolog 2	0.013
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.013
Nab1	Ngfi-A binding protein 1	0.013
Fosb	FBJ osteosarcoma oncogene B	0.013
Hhex	hematopoietically expressed homeobox	0.013
Zeb1	zinc finger E-box binding homeobox 1	0.013
Gsx1	GS homeobox 1	0.013
Pou4f2	POU domain, class 4, transcription factor 2	0.013
Hoxb2	homeobox B2	0.013
Capn9	calpain 9	0.013
Junb	Jun-B oncogene	0.013
Upk3b	uroplakin 3B	0.013
Onecut1	one cut domain, family member 1	0.012
Sh3rf1	SH3 domain containing ring finger 1	0.012
Myf5	myogenic factor 5	0.012
Invs	inversin	0.012
Bdnf	brain derived neurotrophic factor	0.012
Hoxb4	homeobox B4	0.012
Dhh	desert hedgehog	0.012	Mouse
Vegfa	vascular endothelial growth factor A	0.012
Tcf15	transcription factor 15	0.012
Kremen2	kringle containing transmembrane protein 2	0.012
Tdgf1	teratocarcinoma-derived growth factor 1	0.012
Kiss1	KiSS-1 metastasis-suppressor	0.012
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.012
Vax2	ventral anterior homeobox containing gene 2	0.012
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.012
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.012
Sox18	SRY-box containing gene 18	0.012
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.012
Fgf9	fibroblast growth factor 9	0.012
Myog	myogenin	0.012
BC021891	cDNA sequence BC021891	0.012
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.012
Tlx3	T-cell leukemia, homeobox 3	0.011
Pth1r	parathyroid hormone 1 receptor	0.011
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.011
Wnt5b	wingless-related MMTV integration site 5B	0.011
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.011
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.011
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.011
Zbtb46	zinc finger and BTB domain containing 46	0.011
Foxl2	forkhead box L2	0.011	Mouse
Gipc3	GIPC PDZ domain containing family, member 3	0.011
Alx3	aristaless-like homeobox 3	0.011
Fgf4	fibroblast growth factor 4	0.011
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.011
Rsph6a	radial spoke head 6 homolog A (Chlamydomonas)	0.011
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.011
Cdh1	cadherin 1	0.011
Mecom	MDS1 and EVI1 complex locus	0.011
Tmprss2	transmembrane protease, serine 2	0.010
Pax6	paired box gene 6	0.010
Wnt4	wingless-related MMTV integration site 4	0.010
Mesp1	mesoderm posterior 1	0.010
Hoxb5	homeobox B5	0.010