IMP

Process View

Rattus norvegicus

2 genes annotated in rat

antigen processing and presentation

GO:0019882

The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "antigen processing and presentation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "antigen processing and presentation" (in gray)

Name	Description	Probability	Func Analog Organism
RT1-Da	RT1 class II, locus Da	0.986	Human
RT1-Db1	RT1 class II, locus Db1	0.954	Mouse
RT1-EC2	RT1 class Ib, locus EC2	0.821
Cd74	Cd74 molecule, major histocompatibility complex, class II invariant chain	0.708	Mouse
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.562
RT1-Bb	RT1 class II, locus Bb	0.403	Mouse
RT1-DMb	RT1 class II, locus DMb	0.329	Mouse
RT1-Ba	RT1 class II, locus Ba	0.210	Mouse
Ifitm3	interferon induced transmembrane protein 3	0.208
RT1-DMa	RT1 class II, locus DMa	0.187	Human
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.173	Mouse
Irf1	interferon regulatory factor 1	0.159
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.112
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.104
Irf7	interferon regulatory factor 7	0.098
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.084
Lgals3	lectin, galactoside-binding, soluble, 3	0.082
Hck	hemopoietic cell kinase	0.072
Psap	prosaposin	0.072
Ftl	ferritin, light polypeptide	0.059
Pdia3	protein disulfide isomerase family A, member 3	0.059
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.058	Human Rat
Il2rg	interleukin 2 receptor, gamma	0.051
Ifi30	interferon gamma inducible protein 30	0.046
C1qc	complement component 1, q subcomponent, C chain	0.044
Gbp2	guanylate binding protein 2	0.043
Ctsb	cathepsin B	0.043
Ralb	v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)	0.043
Arhgap4	Rho GTPase activating protein 4	0.041
Cxcl10	chemokine (C-X-C motif) ligand 10	0.040
Ifi27l2b	interferon, alpha-inducible protein 27 like 2B	0.040
P4hb	prolyl 4-hydroxylase, beta polypeptide	0.039
LOC100365106	rCG32755-like	0.036
Cd37	CD37 molecule	0.035
Nmi	N-myc (and STAT) interactor	0.034
RT1-Cl	RT1 class Ib, locus Cl	0.033
Pdia4	protein disulfide isomerase family A, member 4	0.031
Pigq	phosphatidylinositol glycan anchor biosynthesis, class Q	0.029
Fn3k	fructosamine 3 kinase	0.027
Lyz2	lysozyme 2	0.026
C1qb	complement component 1, q subcomponent, B chain	0.026
Aif1	allograft inflammatory factor 1	0.026
Plcb2	phospholipase C, beta 2	0.025
Slfn2	schlafen 2	0.025
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.025
Btd	biotinidase	0.025
Sel1l	sel-1 suppressor of lin-12-like (C. elegans)	0.025
Carhsp1	calcium regulated heat stable protein 1	0.025
C2	complement component 2	0.023
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.023
Ifi35	interferon-induced protein 35	0.023
Syngr2	synaptogyrin 2	0.023
Cxcl16	chemokine (C-X-C motif) ligand 16	0.022
Acp5	acid phosphatase 5, tartrate resistant	0.022
Hmox1	heme oxygenase (decycling) 1	0.022
RT1-N3	RT1 class Ib, locus N3	0.022
Ccl5	chemokine (C-C motif) ligand 5	0.022
Cd82	Cd82 molecule	0.021
Coro1b	coronin, actin-binding protein, 1B	0.021
Clec10a	C-type lectin domain family 10, member A	0.021
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.021
Cd53	Cd53 molecule	0.020
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.020
Crybb1	crystallin, beta B1	0.020
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.019
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.019
Tifa	TRAF-interacting protein with forkhead-associated domain	0.019
Asah1	N-acylsphingosine amidohydrolase (acid ceramidase) 1	0.019
Xdh	xanthine dehydrogenase	0.019
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.019
Smad1	SMAD family member 1	0.018
LOC100362108	poly (ADP-ribose) polymerase family, member 10	0.018
Mvp	major vault protein	0.018
Bst2	bone marrow stromal cell antigen 2	0.018
Fgd2	FYVE, RhoGEF and PH domain containing 2	0.018
Gpr4	G protein-coupled receptor 4	0.018
Cd14	CD14 molecule	0.018
Akt1s1	AKT1 substrate 1 (proline-rich)	0.018
Lhx1	LIM homeobox 1	0.018
Esr2	estrogen receptor 2 (ER beta)	0.017
Bcam	basal cell adhesion molecule	0.017
LOC680711	hypothetical protein LOC680711	0.017
Irgm	immunity-related GTPase family, M	0.017
Cfb	complement factor B	0.017
Pyy	peptide YY (mapped)	0.016
Cyba	cytochrome b-245, alpha polypeptide	0.016
Rhog	ras homolog gene family, member G (rho G)	0.016
LOC100362727	ubiquitin carboxyl-terminal hydrolase CYLD	0.016
Parp14	poly (ADP-ribose) polymerase family, member 14	0.016
Stat1	signal transducer and activator of transcription 1	0.016
C3	complement component 3	0.016
Ikbkb	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.016
Rab13	RAB13, member RAS oncogene family	0.016
Junb	jun B proto-oncogene	0.016
Lrrk2	leucine-rich repeat kinase 2	0.015
C4-2	complement component 4, gene 2	0.015
LOC100364854	similar to RIKEN cDNA A430107P09 gene-like	0.015
Plaur	plasminogen activator, urokinase receptor	0.015
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.015
RGD1566001	similar to DNA segment, Chr 4, Brigham & Womens Genetics 0951 expressed	0.015
Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.015
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.015
Rasgrp2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	0.015
Prkch	protein kinase C, eta	0.015
Gpihbp1	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	0.015
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.015
Litaf	lipopolysaccharide-induced TNF factor	0.014
Batf	basic leucine zipper transcription factor, ATF-like	0.014
Serpinb1a	serine (or cysteine) proteinase inhibitor, clade B, member 1a	0.014
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.014
Csrp1	cysteine and glycine-rich protein 1	0.014
RT1-Ha	RT1 class II, locus Ha	0.014
Fgf18	fibroblast growth factor 18	0.014
Myl3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.014
Bid	BH3 interacting domain death agonist	0.014
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.014
Ccl2	chemokine (C-C motif) ligand 2	0.014
Ager	advanced glycosylation end product-specific receptor	0.014
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.014
Rabep1	rabaptin, RAB GTPase binding effector protein 1	0.014
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.014
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.013
Gipc1	GIPC PDZ domain containing family, member 1	0.013
Plac8	placenta-specific 8	0.013
Shh	sonic hedgehog	0.013
Gabarap	GABA(A) receptor-associated protein	0.013
Tmem86a	transmembrane protein 86A	0.013
Anxa1	annexin A1	0.013
Cidea	cell death-inducing DFFA-like effector a	0.013
Akap2	A kinase (PRKA) anchor protein 2	0.013
C1qa	complement component 1, q subcomponent, A chain	0.013
Plekha1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.013
Sept9	septin 9	0.013
Irs3	insulin receptor substrate 3	0.013
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.013
Calca	calcitonin-related polypeptide alpha	0.013
Tapbp	TAP binding protein	0.013
Myd88	myeloid differentiation primary response gene 88	0.013
Oaz2	ornithine decarboxylase antizyme 2	0.013
Dnase2a	deoxyribonuclease II alpha	0.013
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.013
RGD1564599	RGD1564599	0.013
Zfand3	zinc finger, AN1-type domain 3	0.013
Hmg20b	high mobility group 20 B	0.012
Tnfrsf21	tumor necrosis factor receptor superfamily, member 21	0.012
Ccr5	chemokine (C-C motif) receptor 5	0.012
Plek	pleckstrin	0.012
Il1f5	interleukin 1 family, member 5 (delta)	0.012
Nckap1l	NCK associated protein 1 like	0.012
Dhh	desert hedgehog homolog (Drosophila)	0.012
Nudt3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.012
Myo1a	myosin IA	0.012
Inpp5d	inositol polyphosphate-5-phosphatase D	0.012
Car5a	carbonic anhydrase 5a, mitochondrial	0.012
Serpind1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.012
RGD1560608	similar to novel protein	0.012
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.012
LOC100362331	rCG59612-like	0.012
Sirt2	sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)	0.012
Ucn2	urocortin 2	0.012
Rab9b	RAB9B, member RAS oncogene family	0.012
Msmb	microseminoprotein, beta	0.012
RT1-M3-1	RT1 class Ib, locus M3, gene 1	0.012
Ralbp1	ralA binding protein 1	0.012
Dnajc14	DnaJ (Hsp40) homolog, subfamily C, member 14	0.012
Prkcd	protein kinase C, delta	0.012
Gbp5	guanylate binding protein 5	0.012
Ube2d1	ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog (yeast)	0.012
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.012
LOC24906	RoBo-1	0.012
Camk4	calcium/calmodulin-dependent protein kinase IV	0.012
Dmbt1	deleted in malignant brain tumors 1	0.012
Isoc2b	isochorismatase domain containing 2b	0.012
Napsa	napsin A aspartic peptidase	0.012	Rat
Fbxw2	F-box and WD repeat domain containing 2	0.012
Ppp2r4	protein phosphatase 2A activator, regulatory subunit 4	0.012
Plekho2	pleckstrin homology domain containing, family O member 2	0.011
Cd200	Cd200 molecule	0.011
Lamtor1	RhoA activator C11orf59 homolog	0.011
Galm	galactose mutarotase (aldose 1-epimerase)	0.011
Ly6c	Ly6-C antigen	0.011
Aktip	AKT interacting protein	0.011
Lmbrd1	LMBR1 domain containing 1	0.011
Hmha1	histocompatibility (minor) HA-1	0.011
Klk1b21	kallikrein 1-related peptidase b21	0.011
Klf13	Kruppel-like factor 13	0.011
Acsl5	acyl-CoA synthetase long-chain family member 5	0.011
Ubd	ubiquitin D	0.011
Hyal3	hyaluronoglucosaminidase 3	0.011
Kcnn3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	0.011
Lilrb3l	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like	0.011
Dnah5	dynein, axonemal, heavy chain 5	0.011
Rab5c	RAB5C, member RAS oncogene family	0.011
Elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	0.011
Lypd6b	LY6/PLAUR domain containing 6B	0.011
LOC100359454	hypothetical protein LOC100359454	0.011
Prlh	prolactin releasing hormone	0.011
Man1a1	mannosidase, alpha, class 1A, member 1	0.011
Klf6	Kruppel-like factor 6	0.011
Ube2h	ubiquitin-conjugating enzyme E2H	0.011
Tph1	tryptophan hydroxylase 1	0.011
Tmem8a	transmembrane protein 8A	0.011
Mocs3	molybdenum cofactor synthesis 3	0.011
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.011
Cp	ceruloplasmin	0.011
Suox	sulfite oxidase	0.011
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.011
Nppa	natriuretic peptide precursor A	0.011
Gimap9	GTPase, IMAP family member 9	0.011
Spi1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.011
Cd3d	CD3 molecule, delta	0.011
Adm	adrenomedullin	0.011
RT1-CE12	RT1 class I, locus CE12	0.011
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.011
Tnks2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.011
Rab10	RAB10, member RAS oncogene family	0.011
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	0.011
Aph1a	anterior pharynx defective 1 homolog A (C. elegans)	0.011
Tpc1808	tropic 1808	0.011
RGD1560880	similar to RIKEN cDNA 2310002J15	0.011
Dnah2	dynein, axonemal, heavy chain 2	0.011
P2rx5	purinergic receptor P2X, ligand-gated ion channel, 5	0.011
Mdfic	MyoD family inhibitor domain containing	0.011
Wsb2	WD repeat and SOCS box-containing 2	0.011
LOC690206	hypothetical protein LOC690206	0.011
Mfsd5	major facilitator superfamily domain containing 5	0.011
Atrn	attractin	0.011
Fam43a	family with sequence similarity 43, member A	0.011
Icam1	intercellular adhesion molecule 1	0.011	Mouse
Syngr1	synaptogyrin 1	0.011
Neto2	neuropilin (NRP) and tolloid (TLL)-like 2	0.011
Gpr65	G-protein coupled receptor 65	0.011
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.011
Il18r1	interleukin 18 receptor 1	0.011
Chmp1a	chromatin modifying protein 1A	0.011
Crebl2	cAMP responsive element binding protein-like 2	0.011
Cr1l	complement component (3b/4b) receptor 1-like	0.010
Acpp	acid phosphatase, prostate	0.010
Kcnn4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	0.010
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.010
Ncf4	neutrophil cytosolic factor 4	0.010
Esam	endothelial cell adhesion molecule	0.010
Pdzk1ip1	PDZK1 interacting protein 1	0.010
Trim25	tripartite motif-containing 25	0.010
Cd8a	CD8a molecule	0.010
Stat2	signal transducer and activator of transcription 2	0.010
Gja4	gap junction protein, alpha 4	0.010
Sprr3	small proline-rich protein 3	0.010
Sox17	SRY (sex determining region Y)-box 17	0.010
Cd40	CD40 molecule, TNF receptor superfamily member 5	0.010
Sepp1	selenoprotein P, plasma, 1	0.010
Steap4	STEAP family member 4	0.010
Cd47	Cd47 molecule	0.010
Ifi27	interferon, alpha-inducible protein 27	0.010
Efhd2	EF-hand domain family, member D2	0.010
Tagln3	transgelin 3	0.010
Gpr183	G protein-coupled receptor 183	0.010
Hoxc8	homeo box C8	0.010
Ak1	adenylate kinase 1	0.010
Foxr1	forkhead box R1	0.010
Chga	chromogranin A	0.010
Grpcb	glutamine/glutamic acid-rich protein A	0.010
Actc1	actin, alpha, cardiac muscle 1	0.010
Chrm4	cholinergic receptor, muscarinic 4	0.010
Clu	clusterin	0.010
Map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.010
LOC363331	similar to plasma membrane associated protein, S3-12	0.010
Igh-6	immunoglobulin heavy chain 6	0.010
Ctsc	cathepsin C	0.010
Gzmm	granzyme M (lymphocyte met-ase 1)	0.010
RT1-T24-1	RT1 class I, locus T24, gene 1	0.010