IMP

Process View

Danio rerio

1 genes annotated in zebrafish

protein ubiquitination involved in ubiquitin dependent protein catabolic process

The process in which a ubiquitin group, or multiple groups, are covalently attached to the target protein, thereby initiating the degradation of that protein.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein ubiquitination involved in ubiquitin dependent protein catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein ubiquitination involved in ubiquitin dependent protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
slc12a3	solute carrier family 12 (sodium/chloride transporters), member 3	0.127
wnt4a	wingless-type MMTV integration site family, member 4a	0.100
ntn2	netrin 2	0.052
bnip3lb	BCL2/adenovirus E1B interacting protein 3-like b	0.047
lef1	lymphocyte enhancer binding factor 1	0.046
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.046
smad5	MAD homolog 5 (Drosophila)	0.043
rab5aa	RAB5A, member RAS oncogene family, a	0.041
baxa	bcl2-associated X protein, a	0.041
pxn	paxillin	0.040
zgc:77849	zgc:77849	0.036
arf1	ADP-ribosylation factor 1	0.034
zgc:55573	zgc:55573	0.034
supt6h	suppressor of Ty 6 homolog	0.032
pdcd10a	programmed cell death 10a	0.032
slc12a10.2	solute carrier family 12 (sodium/potassium/chloride transporters), member 10.2	0.031
extl3	exostoses (multiple)-like 3	0.031
zgc:55448	zgc:55448	0.030
tmem50a	transmembrane protein 50A	0.030
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.029
sst2	somatostatin 2	0.029
ctnnb1	catenin (cadherin-associated protein), beta 1	0.029
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.028
si:ch211-255l18.3	si:ch211-255l18.3	0.027
acvr1l	activin A receptor, type I like	0.025
erbb3a	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a	0.025
wnt8b	wingless-type MMTV integration site family, member 8b	0.024
gro2	groucho 2	0.024
stau1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.024
grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.023
arpc2	actin related protein 2/3 complex, subunit 2	0.023
mbd3a	methyl-CpG binding domain protein 3a	0.023
ctsd	cathepsin D	0.022
rnf2	ring finger protein 2	0.021
chuk	conserved helix-loop-helix ubiquitous kinase	0.021
psen2	presenilin 2	0.021	Mouse
sdcbp	syndecan binding protein (syntenin)	0.021
sp7	Sp7 transcription factor	0.021
papolg	poly(A) polymerase gamma	0.020
utrn	utrophin	0.020
egr2b	early growth response 2b	0.020
wu:fc24e06	wu:fc24e06	0.020
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.020
hsd17b12b	hydroxysteroid (17-beta) dehydrogenase 12b	0.020
tmem199	transmembrane protein 199	0.019
casp8	caspase 8, apoptosis-related cysteine peptidase	0.019
sirt1	sirtuin (silent mating type information regulation 2 homolog) 1	0.019
wipi2	WD repeat domain, phosphoinositide interacting 2	0.019
chic2	cysteine-rich hydrophobic domain 2	0.019
usp25	ubiquitin specific protease 25	0.019
tpp1	tripeptidyl peptidase I	0.019
fmr1	fragile X mental retardation 1	0.019
tectb	tectorin beta	0.018
bmp1a	bone morphogenetic protein 1a	0.018
zgc:101121	zgc:101121	0.018
stac3	SH3 and cysteine rich domain 3	0.018
eda	ectodysplasin A	0.018
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.018
cnnm2a	cyclin M2a	0.018
arih2	ariadne homolog 2 (Drosophila)	0.018	Human
LOC568379	von Willebrand factor A domain-containing protein 1-like	0.018
cfl2l	cofilin 2, like	0.018
plekhf2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.017
flii	flightless I homolog (Drosophila)	0.017
LOC565256	similar to Metabotropic glutamate receptor 3 precursor (mGluR3)	0.017
kcnk5	potassium channel, subfamily K, member 5	0.017
slc2a1a	solute carrier family 2 (facilitated glucose transporter), member 1a	0.017
maea	macrophage erythroblast attacher	0.017
pi4kb	phosphatidylinositol 4-kinase, catalytic, beta	0.017
zgc:73230	zgc:73230	0.017
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.016
gnsb	glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b	0.016
LOC100149353	transient receptor potential cation channel subfamily M member 6-like	0.016
usp14	ubiquitin specific protease 14 (tRNA-guanine transglycosylase)	0.016
fibp	fibroblast growth factor (acidic) intracellular binding protein	0.016
zgc:92765	zgc:92765	0.016
wu:fc51d09	wu:fc51d09	0.016
hsp90a.1	heat shock protein 90-alpha 1	0.016
wwp1	WW domain containing E3 ubiquitin protein ligase 1	0.015
lrmp	lymphoid-restricted membrane protein	0.015
sept7b	septin 7b	0.015
rab40c	RAB40c, member RAS oncogene family	0.015
zfand5b	zinc finger, AN1-type domain 5b	0.015
eif1b	eukaryotic translation initiation factor 1B	0.015
zgc:103670	zgc:103670	0.015
cdc34b	cell division cycle 34 homolog (S. cerevisiae) b	0.015
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.015
LOC100331628	tumor necrosis factor ligand superfamily member 11-like	0.015
tsc22d2	TSC22 domain family 2 and TSC22 domain family, member 2	0.015
plekha3	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3	0.015
phox2a	paired-like homeobox 2a	0.015
zfr	zinc finger RNA binding protein	0.015
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.015
pdcd10b	programmed cell death 10b	0.015
ranbp9	RAN binding protein 9	0.015
LOC567131	calcitonin gene-related peptide type 1 receptor-like	0.015
ncor1	nuclear receptor co-repressor 1	0.014
stam	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.014
golga7	golgi autoantigen, golgin subfamily a, 7	0.014
napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.014
glcea	glucuronyl C5-epimerase a	0.014
rfng	radical fringe homolog (Drosophila)	0.014
exoc7	exocyst complex component 7	0.014
gsk3a	glycogen synthase kinase 3 alpha	0.014
irak4	interleukin-1 receptor-associated kinase 4	0.014
ep300b	E1A binding protein p300 b	0.014
col1a1b	collagen, type I, alpha 1b	0.014
dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.014
aktip	akt interacting protein	0.014
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.014
ube2h	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.014	Yeast
im:7142942	im:7142942	0.014
egln3	egl nine homolog 3 (C. elegans)	0.014
ctsl1a	cathepsin L, 1 a	0.014
ube2d1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.014
ppp1caa	protein phosphatase 1, catalytic subunit, alpha isoform a	0.014
exoc3	exocyst complex component 3	0.014
fbxo30	F-box protein 30	0.013
zgc:66260	zgc:66260	0.013
zgc:112211	zgc:112211	0.013
zgc:66160	zgc:66160	0.013
zgc:56706	zgc:56706	0.013
cldn12	claudin 12	0.013
slc26a5	solute carrier family 26, member 5	0.013
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.013
stau2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.013
psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.013
nudt5	nudix (nucleoside diphosphate linked moiety X)-type motif 5	0.013
sb:cb560	sb:cb560	0.013
zgc:153148	zgc:153148	0.013
dcaf7	ddb1 and cul4 associated factor 7	0.013
atg13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.013
lancl1	LanC antibiotic synthetase component C-like 1 (bacterial)	0.013
wnt11	wingless-type MMTV integration site family, member 11	0.013
ube2g2	ubiquitin-conjugating enzyme E2G 2	0.013
ankra2	ankyrin repeat, family A (RFXANK-like), 2	0.013
ghitm	growth hormone inducible transmembrane protein	0.013
blmh	bleomycin hydrolase	0.013
ythdf3	YTH domain family 3	0.012
dennd5b	DENN/MADD domain containing 5B	0.012
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.012
supt3h	suppressor of Ty 3 homolog (S. cerevisiae)	0.012
dub	duboraya	0.012
zgc:153629	zgc:153629	0.012
ppt1	palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)	0.012
rab1a	RAB1A, member RAS oncogene family	0.012
psap	prosaposin	0.012
foxo3b	forkhead box O3b	0.012
ube2q2	ubiquitin-conjugating enzyme E2Q family member 2	0.012
klhl11	kelch-like 11 (Drosophila)	0.012
ugt2a6	UDP glucuronosyltransferase 2 family, polypeptide A6	0.012
mapk3	mitogen-activated protein kinase 3	0.012
zwi	zwilling	0.012
slc2a8	solute carrier family 2 (facilitated glucose transporter), member 8	0.012
ppp2r5eb	protein phosphatase 2, regulatory subunit B', epsilon isoform b	0.012
sybl1	synaptobrevin-like 1	0.012
cldn11a	claudin 11a	0.012
htra1a	HtrA serine peptidase 1a	0.012
zgc:101761	zgc:101761	0.012
tmem110l	transmembrane protein 110, like	0.012
nrg1	neuregulin 1	0.012
epha4a	eph receptor A4a	0.012
rab11ba	RAB11B, member RAS oncogene family, a	0.012
ctdsp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	0.012
st13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.012
thraa	thyroid hormone receptor alpha a	0.012
si:ch211-191i18.1	si:ch211-191i18.1	0.011
cry1b	cryptochrome 1b	0.011
ppp4r1	protein phosphatase 4, regulatory subunit 1	0.011
kdm5c	lysine (K)-specific demethylase 5C	0.011
fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.011	Yeast
nrarpa	notch-regulated ankyrin repeat protein a	0.011
LOC796298	isotocin receptor-like 1	0.011
zgc:171495	zgc:171495	0.011
sumf1	sulfatase modifying factor 1	0.011
aup1	ancient ubiquitous protein 1	0.011
sec14l1	SEC14-like 1 (S. cerevisiae)	0.011
hcrtr2	hypocretin (orexin) receptor 2	0.011
bactin2	bactin2	0.011
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.011
trpc1	transient receptor potential cation channel, subfamily C, member 1	0.011
aldh1a3	aldehyde dehydrogenase 1 family, member A3	0.011
zgc:77513	zgc:77513	0.011
cyp24a1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.011
ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.011
zfand5a	zinc finger, AN1-type domain 5a	0.011
zgc:55671	zgc:55671	0.011
slc43a2a	solute carrier family 43, member 2a	0.011
prelid1	PRELI domain containing 1	0.011
rab12	RAB12, member RAS oncogene family	0.011
srrm1	serine/arginine repetitive matrix 1	0.011
tia1l	cytotoxic granule-associated RNA binding protein 1, like	0.011
plxnb2b	plexin b2b	0.011
nrg2a	neuregulin 2a	0.011
zgc:56525	zgc:56525	0.011
klhl20	kelch-like 20 (Drosophila)	0.011
fgf20b	fibroblast growth factor 20b	0.011
zgc:55886	zgc:55886	0.011
npc1	Niemann-Pick disease, type C1	0.011
mespb	mesoderm posterior b	0.011
si:dkey-114g7.4	si:dkey-114g7.4	0.011
pnrc2	proline-rich nuclear receptor coactivator 2	0.011
wnt4b	wingless-type MMTV integration site family, member 4b	0.011
slc25a43	solute carrier family 25, member 43	0.011
LOC561406	prostacyclin receptor-like	0.011
cecr1a	cat eye syndrome chromosome region, candidate 1a	0.011
psen1	presenilin 1	0.011	Mouse
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.011
ryk	receptor-like tyrosine kinase	0.011
ubxn4	UBX domain protein 4	0.011
stard3	START domain containing 3	0.011
rhoub	ras homolog gene family, member Ub	0.011
faf2	Fas associated factor family member 2	0.011
zfand2a	zinc finger, AN1-type domain 2A	0.011
si:dkey-60b12.7	si:dkey-60b12.7	0.011
pi4k2a	phosphatidylinositol 4-kinase type 2 alpha	0.011
slc25a25a	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a	0.011
mtmr6	myotubularin related protein 6	0.011
dcun1d2	DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae)	0.011
hspa8	heat shock protein 8	0.011
bbc3	BCL2 binding component 3	0.010
dzip1	DAZ interacting protein 1	0.010
si:ch211-251b21.1	si:ch211-251b21.1	0.010
zgc:73311	zgc:73311	0.010
npepl1	aminopeptidase-like 1	0.010
foxk1	forkhead box K1	0.010
sat1a	spermidine/spermine N1-acetyltransferase 1a	0.010
psmd4b	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b	0.010
cdc37	cell division cycle 37 homolog (S. cerevisiae)	0.010
spsb4a	splA/ryanodine receptor domain and SOCS box containing 4a	0.010
hgs	hepatocyte growth factor-regulated tyrosine kinase substrate	0.010
snx27	sorting nexin family member 27	0.010
foxd3	forkhead box D3	0.010
ubl7	ubiquitin-like 7	0.010
vipr1	vasoactive intestinal peptide receptor 1	0.010
cnppd1	cyclin Pas1/PHO80 domain containing 1	0.010
ocrl	oculocerebrorenal syndrome of Lowe	0.010
cask	calcium/calmodulin-dependent serine protein kinase	0.010
thrap6	thyroid hormone receptor associated protein 6	0.010
zgc:63514	zgc:63514	0.010
ndel1b	nudE nuclear distribution gene E homolog like 1 (A. nidulans) B	0.010
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.010
hint2	histidine triad nucleotide binding protein 2	0.010
cdc42	cell division cycle 42	0.010
ppp1cbl	protein phosphatase 1, catalytic subunit, beta isoform, like	0.010
kctd12.2	potassium channel tetramerisation domain containing 12.2	0.010
cry4	cryptochrome 4	0.010
kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.010
eif4a1a	eukaryotic translation initiation factor 4A, isoform 1A	0.010
robo1	roundabout homolog 1	0.010