IMP

Process View

Danio rerio

8 genes annotated in zebrafish

endochondral bone morphogenesis

The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.

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In addition to gene-name show these genes:

Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "endochondral bone morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "endochondral bone morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
gli2a	GLI-Kruppel family member GLI2a	0.969
sox9a	SRY-box containing gene 9a	0.967	Human Mouse
wu:fv91b12	wu:fv91b12	0.913
foxi1	forkhead box I1	0.842	Zebrafish
col5a1	procollagen, type V, alpha 1	0.782
sox10	SRY-box containing gene 10	0.655
efnb2a	ephrin B2a	0.653
gdf6a	growth differentiation factor 6a	0.591
bmp2b	bone morphogenetic protein 2b	0.582
col1a2	collagen, type I, alpha 2	0.508
prdm1a	PR domain containing 1a, with ZNF domain	0.501
jag1b	jagged 1b	0.489
edn1	endothelin 1	0.474
shha	sonic hedgehog a	0.359
raraa	retinoic acid receptor, alpha a	0.319	Mouse
col12a1	collagen, type XII, alpha 1	0.313
chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1	0.282
lect1	leukocyte cell derived chemotaxin 1	0.268
notch1a	notch homolog 1a	0.248	Zebrafish
bmper	BMP binding endothelial regulator	0.246
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.220
cmn	calymmin	0.187
mdka	midkine-related growth factor	0.185
col9a3	collagen, type IX, alpha 3	0.175
foxa2	forkhead box A2	0.169	Zebrafish
nkx3.2	NK3 homeobox 2	0.154
tfe3b	transcription factor binding to IGHM enhancer 3b	0.143
col5a2l	collagen, type V, alpha 2-like	0.128
myod1	myogenic differentiation 1	0.119
twist2	twist2	0.106
ctgf	connective tissue growth factor	0.103
dlx2a	distal-less homeobox gene 2a	0.094
barx1	BarH-like homeobox 1	0.092
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.088
pax7a	paired box gene 7a	0.082
gbx2	gastrulation brain homeo box 2	0.071
lmo4a	LIM domain only 4a	0.070
runx3	runt-related transcription factor 3	0.066
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.065
bmp4	bone morphogenetic protein 4	0.062	Mouse
itga5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.060
foxa3	forkhead box A3	0.056	Zebrafish
tp63	tumor protein p63	0.056
eya1	eyes absent homolog 1	0.053
fgf3	fibroblast growth factor 3	0.052
pkd2	polycystic kidney disease 2	0.052
msxc	muscle segment homeobox C	0.052
tbx5a	T-box 5a	0.049
runx2a	runt-related transcription factor 2a	0.049	Mouse
col9a2	procollagen, type IX, alpha 2	0.047
dcn	decorin	0.047
fgfr2	fibroblast growth factor receptor 2	0.043
foxi3b	forkhead box I3b	0.043	Zebrafish
foxc1a	forkhead box C1a	0.043
cdx4	caudal type homeo box transcription factor 4	0.043
pxn	paxillin	0.043
hoxa10b	homeo box A10b	0.038
col1a1a	collagen, type I, alpha 1a	0.037	Mouse
sox2	SRY-box containing gene 2	0.036
ntla	no tail a	0.036
foxa1	forkhead box A1	0.036	Zebrafish
si:xx-bac7cse.2	si:xx-bac7cse.2	0.035
matn4	matrilin 4	0.035
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.035
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.034
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.033
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.032
hoxd12a	homeo box D12a	0.032
neurog1	neurogenin 1	0.032
twist1b	twist1b	0.031
hoxd10a	homeo box D10a	0.030
otx2	orthodenticle homolog 2	0.030
cart1	cartilage paired-class homeoprotein 1	0.030
si:ch211-173b8.2	si:ch211-173b8.2	0.030
tfap2a	transcription factor AP-2 alpha	0.029
tbx24	T-box 24	0.028
foxi3a	forkhead box I3a	0.028	Zebrafish
pax6a	paired box gene 6a	0.028
rbp4	retinol binding protein 4, plasma	0.028
rlbp1a	retinaldehyde binding protein 1a	0.028
crestin	crestin	0.027
grhl1	grainyhead-like 1 (Drosophila)	0.026
foxb1.1	forkhead box B1.1	0.026	Zebrafish
ptch2	patched 2	0.026
fn1	fibronectin 1	0.025
hapln1a	hyaluronan and proteoglycan link protein 1a	0.025
pax7b	paired box gene 7b	0.025
rxrab	retinoid x receptor, alpha b	0.024
ehd2	EH-domain containing 2	0.024
dld	deltaD	0.023	Zebrafish
notch3	notch homolog 3	0.022	Zebrafish
sparc	secreted acidic cysteine rich glycoprotein	0.022
fgfrl1a	fibroblast growth factor receptor-like 1a	0.022
gpr126	G protein-coupled receptor 126	0.022
fgf8b	fibroblast growth factor 8 b	0.022
kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.022
hoxd13a	homeo box D13a	0.022
mgp	matrix Gla protein	0.022
zgc:85866	zgc:85866	0.021
hand2	heart and neural crest derivatives expressed transcript 2	0.021
hmx4	H6 family homeobox 4	0.021
sp7	Sp7 transcription factor	0.020
col2a1a	collagen type II, alpha-1a	0.019	Mouse Rat
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.019
dlb	deltaB	0.019	Zebrafish
epha4b	eph receptor A4b	0.018
neo1	neogenin 1	0.018
hs6st3	heparan sulfate 6-O-sulfotransferase 3	0.017
cldn5a	claudin 5a	0.017
msxb	muscle segment homeobox B	0.017
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.017
jag1a	jagged 1a	0.017	Zebrafish
bmp2a	bone morphogenetic protein 2a	0.017
ihhb	Indian hedgehog homolog b	0.016
isl1	islet1	0.016
six3a	sine oculis homeobox homolog 3a	0.016
pax8	paired box gene 8	0.016
cdh15	cadherin 15, M-cadherin (myotubule)	0.016
dmrt2a	doublesex and mab-3 related transcription factor 2a	0.016
msgn1	mesogenin 1	0.015
fgfrl1b	fibroblast growth factor receptor-like 1b	0.015
hoxd9a	homeo box D9a	0.015
twist1a	twist1a	0.015
grem2	gremlin 2, cysteine knot superfamily	0.015
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.015
hoxb3a	homeo box B3a	0.015
lama2	laminin, alpha 2	0.015
pitx3	paired-like homeodomain transcription factor 3	0.015
gata3	GATA-binding protein 3	0.015
wnt11	wingless-type MMTV integration site family, member 11	0.015
neb	nebulin	0.015
postn	periostin, osteoblast specific factor	0.015
col27a1a	collagen, type XXVII, alpha 1a	0.014	Mouse
has3	hyaluronan synthase 3	0.014
ctsl1b	cathepsin L, 1 b	0.014
six4b	sine oculis homeobox homolog 4b	0.014
nkx2.3	NK2 transcription factor related 3	0.014
bmp7b	bone morphogenetic protein 7b	0.014
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.014
mmp2	matrix metalloproteinase 2	0.013
mmp15b	matrix metallopeptidase 15b	0.013
ahr2	aryl hydrocarbon receptor 2	0.013
spns2	spinster homolog 2 (Drosophila)	0.013
nog3	noggin 3	0.013
lhx1b	LIM homeobox 1b	0.013
cx30.3	connexin 30.3	0.012
thbs4b	thrombospondin 4b	0.012
fabp11a	fatty acid binding protein 11a	0.012
rx3	retinal homeobox gene 3	0.012
gli3	GLI-Kruppel family member GLI3	0.012
prdm5	PR domain containing 5	0.012
prrx1a	paired related homeobox 1a	0.012
mylz3	myosin, light polypeptide 3, skeletal muscle	0.012
zgc:85942	zgc:85942	0.012
LOC100000500	sclerostin-like	0.012
fgf20b	fibroblast growth factor 20b	0.011
si:ch211-212m21.5	si:ch211-212m21.5	0.011
hapln3	hyaluronan and proteoglycan link protein 3	0.011
fgf20a	fibroblast growth factor 20a	0.011
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.011	Zebrafish
scxa	scleraxis homolog A (mouse)	0.011
runx2b	runt-related transcription factor 2b	0.011	Mouse
gch2	GTP cyclohydrolase 2	0.011
hoxb5a	homeo box B5a	0.011
zgc:85838	zgc:85838	0.011
pcdh10b	protocadherin 10b	0.011
tbx15	T-box 15	0.010
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.010
notch1b	notch homolog 1b	0.010	Zebrafish
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.010
slc2a1a	solute carrier family 2 (facilitated glucose transporter), member 1a	0.010