IMP

Process View

Danio rerio

10 genes annotated in zebrafish

mrna splicing via spliceosome

The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in zebrafish Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mrna splicing via spliceosome"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mrna splicing via spliceosome" (in gray)

Name	Description	Probability	Func Analog Organism
snrnp70	small nuclear ribonucleoprotein 70 (U1)	0.957
srsf2	serine/arginine-rich splicing factor 2	0.896	Mouse Fly
safb	scaffold attachment factor B	0.882	Fly
khdrbs1a	KH domain containing, RNA binding, signal transduction associated 1a	0.862	Fly
snrpd3l	small nuclear ribonucleoprotein D3 polypeptide, like	0.786
rbmx	RNA binding motif protein, X-linked	0.766	Human Rat
snrpb2	small nuclear ribonucleoprotein polypeptide B2	0.753
sap18	sin3-associated polypeptide	0.600	Human
snrpd1	small nuclear ribonucleoprotein D1 polypeptide	0.556	Human
smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	0.540	Worm
setb	SET translocation (myeloid leukemia-associated) B	0.514
api5	apoptosis inhibitor 5	0.513
srsf11	serine/arginine-rich splicing factor 11	0.475	Fly
hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.348	Fly
ilf2	interleukin enhancer binding factor 2	0.346
sf3b1	splicing factor 3b, subunit 1	0.288
ube2nb	ubiquitin-conjugating enzyme E2Nb	0.287
luc7l	LUC7-like (S. cerevisiae)	0.278	Yeast
phf5a	PHD finger protein 5A	0.274	Human
snrpd3	small nuclear ribonucleoprotein D3 polypeptide	0.272	Human
hnrnph1l	heterogeneous nuclear ribonucleoprotein H1, like	0.264
srsf5a	serine/arginine-rich splicing factor 5a	0.251	Fly
calm3b	calmodulin 3b (phosphorylase kinase, delta)	0.210
elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.206	Worm
acin1a	apoptotic chromatin condensation inducer 1a	0.204	Human
tra2a	transformer-2 alpha	0.202	Human Fly
sart1	squamous cell carcinoma antigen recognised by T cells	0.199
u2af1	U2(RNU2) small nuclear RNA auxiliary factor 1	0.199	Fly
srsf6a	serine/arginine-rich splicing factor 6a	0.197	Human Fly
sf1	splicing factor 1	0.175
matr3l	matrin 3-like	0.162
sumo3a	SMT3 suppressor of mif two 3 homolog 3a	0.160
zgc:55870	zgc:55870	0.155
mbnl2	muscleblind-like 2 (Drosophila)	0.153	Mouse
eif4a3	eukaryotic translation initiation factor 4A, isoform 3	0.153	Mouse
anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.141
zgc:136380	zgc:136380	0.141
tcea1	transcription elongation factor A (SII), 1	0.139
ilf3b	interleukin enhancer binding factor 3b	0.133
sfrs3b	splicing factor, arginine/serine-rich 3b	0.133
zgc:92194	zgc:92194	0.132
srsf6b	serine/arginine-rich splicing factor 6b	0.131	Human Fly
pcf11	cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)	0.131
xrn2	5'-3' exoribonuclease 2	0.129
rbm39a	RNA binding motif protein 39a	0.126	Fly
rbm8a	RNA binding motif protein 8A	0.125	Human
zgc:77052	zgc:77052	0.124	Fly
eftud2	elongation factor Tu GTP binding domain containing 2	0.120	Yeast
anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.114
ddx42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42	0.113
rbm39b	RNA binding motif protein 39b	0.106
ube2v2	ubiquitin-conjugating enzyme E2 variant 2	0.104
sf3b5	splicing factor 3b, subunit 5	0.103
zgc:77155	zgc:77155	0.090
si:ch211-59d15.5	si:ch211-59d15.5	0.078
ddx39b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39b	0.078	Human Yeast Fly
bub3	BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)	0.078
hnrnpa1	heterogeneous nuclear ribonucleoprotein A1	0.075	Mouse Fly
trnau1apl	tRNA selenocysteine 1 associated protein 1, like	0.075
zgc:56388	zgc:56388	0.073
ewsr1a	Ewing sarcoma breakpoint region 1a	0.071
si:dkey-181m9.9	si:dkey-181m9.9	0.071
sf3a2	splicing factor 3a, subunit 2	0.069
znf207b	zinc finger protein 207, b	0.067
srsf1b	serine/arginine-rich splicing factor 1b	0.066	Human Yeast
rnps1	RNA binding protein S1, serine-rich domain	0.064	Human
h3f3c	H3 histone, family 3C	0.064
thoc1	THO complex 1	0.064
prpf31	PRP31 pre-mRNA processing factor 31 homolog (yeast)	0.064
eif4e	eukaryotic translation initiation factor 4e	0.061
snrpa	small nuclear ribonucleoprotein polypeptide A	0.061
ddx19	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)	0.060
srsf4	serine/arginine-rich splicing factor 4	0.059
mbd3a	methyl-CpG binding domain protein 3a	0.058
smx5	smx5	0.057
prpf8	pre-mRNA processing factor 8	0.057
hnrpl	heterogeneous nuclear ribonucleoprotein L	0.056
acvr1l	activin A receptor, type I like	0.055
hnrnpm	heterogeneous nuclear ribonucleoprotein M	0.053	Human
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.053
pcbp2	poly(rC) binding protein 2	0.051	Fly
atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.051
dhx16	DEAH (Asp-Glu-Ala-His) box polypeptide 16	0.050	Yeast
nup50	nucleoporin 50	0.050
znf207a	zinc finger protein 207, a	0.049
pqbp1l	polyglutamine binding protein 1-like	0.049	Human
ubtf	upstream binding transcription factor, RNA polymerase I	0.049
h3f3b.1	H3 histone, family 3B.1	0.049
sart3	squamous cell carcinoma antigen recognised by T cells 3	0.048
si:ch211-51e12.7	si:ch211-51e12.7	0.047
zgc:86598	zgc:86598	0.047
zgc:110325	zgc:110325	0.046
snrpc	small nuclear ribonucleoprotein polypeptide C	0.045
ddx39aa	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa	0.044	Human Yeast Fly
ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.043
puf60b	poly-U binding splicing factor b	0.041	Fly
zgc:112425	zgc:112425	0.041
ck2b	casein kinase 2 beta	0.041
smarce1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.041
hnrnpul1	heterogeneous nuclear ribonucleoprotein U-like 1	0.039
zgc:110717	zgc:110717	0.039
zgc:112305	zgc:112305	0.039
ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.038	Human Fly
cwf19l1	CWF19-like 1, cell cycle control	0.038
prpf39	PRP39 pre-mRNA processing factor 39 homolog (yeast)	0.038
med18	mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)	0.036
eif2s1l	eukaryotic translation initiation factor 2, subunit 1 alpha, like	0.036
zgc:56039	zgc:56039	0.035
rqcd1	RCD1 required for cell differentiation1 homolog (S. pombe)	0.035
syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	0.033
ctbp1	C-terminal binding protein 1	0.033
si:dkey-250d21.1	si:dkey-250d21.1	0.033
zgc:112982	zgc:112982	0.033
lsm8	LSM8 homolog, U6 small nuclear RNA associated	0.033
tgif1	TGFB-induced factor homeobox 1	0.033
h2afv	H2A histone family, member V	0.032
ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.032
nola1	nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs)	0.032
psmd10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.032
lancl1	LanC antibiotic synthetase component C-like 1 (bacterial)	0.031
srsf1a	serine/arginine-rich splicing factor 1a	0.031	Human Yeast
im:7153552	im:7153552	0.031
tada3l	transcriptional adaptor 3 (NGG1 homolog, yeast)-like	0.031
rbm4.2	RNA binding motif protein 4.2	0.030	Human
erh	enhancer of rudimentary homolog (Drosophila)	0.030
zgc:55695	zgc:55695	0.030
zgc:103482	zgc:103482	0.029
hnrnpl2	heterogeneous nuclear ribonucleoprotein L2	0.029
ilf3a	interleukin enhancer binding factor 3a	0.029
dazl	daz-like gene	0.029
zgc:73265	zgc:73265	0.028
caprin1a	cell cycle associated protein 1a	0.028
h2afvl	H2A histone family, member V, like	0.028
diexf	digestive organ expansion factor homolog	0.027
dag1	dystroglycan 1	0.027
gabpb2a	GA repeat binding protein, beta 2a	0.026
mphosph8	M-phase phosphoprotein 8	0.026
im:7141335	im:7141335	0.025
seta	SET translocation (myeloid leukemia-associated) A	0.025
polr2j	polymerase (RNA) II (DNA directed) polypeptide J	0.025
clstn2	calsyntenin 2	0.025
LOC100330645	heterogeneous nuclear ribonucleoprotein U-like protein 1-like	0.025
kdm1a	lysine (K)-specific demethylase 1a	0.024
ewsr1b	Ewing sarcoma breakpoint region 1b	0.024
utp6	UTP6, small subunit (SSU) processome component, homolog (yeast)	0.024
eif1b	eukaryotic translation initiation factor 1B	0.024
zgc:77262	zgc:77262	0.024
rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.024
ppp1r10	protein phosphatase 1, regulatory subunit 10	0.023
cand1	cullin-associated and neddylation-dissociated 1	0.023
fubp1	far upstream element (FUSE) binding protein 1	0.023
snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.023
gemin5	gem (nuclear organelle) associated protein 5	0.023
ptbp1b	polypyrimidine tract binding protein 1b	0.023	Human Mouse
cpsf2	cleavage and polyadenylation specific factor 2	0.022
ogt.2	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 2	0.022
polr2f	polymerase (RNA) II (DNA directed) polypeptide F	0.022
exosc6	exosome component 6	0.021
leo1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.021
xab2	XPA binding protein 2	0.021
cirbp	cold inducible RNA binding protein	0.021
kpna4	karyopherin alpha 4 (importin alpha 3)	0.021
magoh	mago-nashi homolog, proliferation-associated (Drosophila)	0.021	Human
cpsf5	cleavage and polyadenylation specific factor 5	0.020
hnrpdl	heterogeneous nuclear ribonucleoprotein D-like	0.020	Fly
pcdh2ac	protocadherin 2 alpha c	0.020
tardbpl	TAR DNA binding protein, like	0.019
med20	mediator complex subunit 20	0.019
ddx26b	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B	0.019
hnrnpa0	heterogeneous nuclear ribonucleoprotein A0	0.019	Fly
taf7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.019
si:dkey-67c22.2	si:dkey-67c22.2	0.018
gtf2f1	general transcription factor IIF, polypeptide 1	0.018
khdrbs1b	KH domain containing, RNA binding, signal transduction associated 1b	0.018	Fly
eif4h	eukaryotic translation initiation factor 4h	0.018
ddx56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56	0.018
zfr	zinc finger RNA binding protein	0.018
bms1l	BMS1-like, ribosome assembly protein (yeast)	0.018
arglu1b	arginine and glutamate rich 1b	0.018
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.018
wu:fb17g07	wu:fb17g07	0.017
upf1	upf1 regulator of nonsense transcripts homolog (yeast)	0.017
eif3s10	eukaryotic translation initiation factor 3, subunit 10 (theta)	0.017
rnf40	ring finger protein 40	0.017
imp3	IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)	0.017
wdr82	WD repeat domain containing 82	0.017
smn1	survival motor neuron 1	0.017
si:dkey-204a24.9	si:dkey-204a24.9	0.017
wu:fb58e05	wu:fb58e05	0.016
med10	mediator of RNA polymerase II transcription, subunit 10 homolog	0.016
myf5	myogenic factor 5	0.016
atf4b2	activating transcription factor 4b2	0.016
sf3b14	splicing factor 3B	0.016
dhx15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.016
ss18	synovial sarcoma translocation, chromosome 18 (H. sapiens)	0.016
smndc1	survival motor neuron domain containing 1	0.016
hmga1a	high mobility group AT-hook 1a	0.016
dbt	dihydrolipoamide branched chain transacylase E2	0.015
wrb	tryptophan rich basic protein	0.015
si:ch211-198a12.6	si:ch211-198a12.6	0.015
arid4a	AT rich interactive domain 4A (RBP1-like)	0.015
dmap1	DNA methyltransferase 1 associated protein 1	0.015
usp10	ubiquitin specific peptidase 10	0.015
chuk	conserved helix-loop-helix ubiquitous kinase	0.015
wu:fc27e05	wu:fc27e05	0.015
nktr	natural killer-tumor recognition sequence	0.014
cd99l2	CD99 antigen-like 2	0.014
zgc:112242	zgc:112242	0.014
lrrn1	leucine rich repeat neuronal 1	0.014
hug	HuG	0.014	Worm
t54l	T54 protein-like	0.014
zgc:56148	zgc:56148	0.014
pdcd4a	programmed cell death 4a	0.014
ints6	integrator complex subunit 6	0.014
oaz2a	ornithine decarboxylase antizyme 2a	0.014
hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.014	Mouse
wu:fa99c08	wu:fa99c08	0.013
zmat2	zinc finger, matrin type 2	0.013
rnpc3	RNA-binding region (RNP1, RRM) containing 3	0.013
zgc:56596	zgc:56596	0.013
exosc2	exosome component 2	0.013
chrnd	cholinergic receptor, nicotinic, delta polypeptide	0.013
LOC100331798	histone H3.3-like	0.013
ctnna	catenin (cadherin-associated protein), alpha	0.013
yy1a	YY1 transcription factor a	0.013
c1d	C1D nuclear receptor co-repressor	0.013
hp1bp3	heterochromatin protein 1, binding protein 3	0.013
syt11a	synaptotagmin XIa	0.013
cstf1	cleavage stimulation factor, 3' pre-RNA, subunit 1	0.013
zgc:103697	zgc:103697	0.013
nnt	nicotinamide nucleotide transhydrogenase	0.013
thoc6	THO complex 6 homolog (Drosophila)	0.012
ube2i2	ubiquitin-conjugating enzyme E2I2	0.012
cct8	chaperonin containing TCP1, subunit 8 (theta)	0.012
nmnat2	nicotinamide nucleotide adenylyltransferase 2	0.012
zgc:103440	zgc:103440	0.012
nsun2	NOL1/NOP2/Sun domain family, member 2	0.012
tardbp	TAR DNA binding protein	0.012
sf3b4	splicing factor 3b, subunit 4	0.012	Mouse
ppp2r2d	protein phosphatase 2, regulatory subunit B, delta isoform	0.012
cacna1ab	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b	0.012
dhx37	DEAH (Asp-Glu-Ala-His) box polypeptide 37	0.011
ttc4	tetratricopeptide repeat domain 4	0.011
zgc:110664	zgc:110664	0.011
dnajc11	DnaJ (Hsp40) homolog, subfamily C, member 11	0.011
bcas2	breast carcinoma amplified sequence 2	0.011
hnrnpa0l	heterogeneous nuclear ribonucleoprotein A0, like	0.011
si:zfos-47c12.1	si:zfos-47c12.1	0.011
dbr1	debranching enzyme homolog 1 (S. cerevisiae)	0.011
ctnnbl1	catenin, beta like 1	0.011
nova2	neuro-oncological ventral antigen 2	0.011
gspt1l	G1 to S phase transition 1, like	0.011
akap8l	A kinase (PRKA) anchor protein 8-like	0.011
calm1a	calmodulin 1a	0.011
ppp1cab	protein phosphatase 1, catalytic subunit, alpha isoform b	0.011
supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.011
zgc:92611	zgc:92611	0.011
wu:fi04f09	wu:fi04f09	0.011
smfn	small fragment nuclease	0.011
mapkapk2a	mitogen-activated protein kinase-activated protein kinase 2a	0.011
hes6	hairy and enhancer of split 6 (Drosophila)	0.011
ube2q2	ubiquitin-conjugating enzyme E2Q family member 2	0.011
mta2	metastasis associated 1 family, member 2	0.011
dnaja1l	DnaJ (Hsp40) homolog, subfamily A, member 1, like	0.010
si:dkey-50p8.3	si:dkey-50p8.3	0.010
zgc:109901	zgc:109901	0.010
elf2b	E74-like factor 2b (ets domain transcription factor)	0.010
rbm4.3	RNA binding motif protein 4.3	0.010
ints9	integrator complex subunit 9	0.010
gabpa	GA-binding protein transcription factor, alpha subunit	0.010
rltpr	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	0.010
nhp2	NHP2 ribonucleoprotein homolog (yeast)	0.010
lppr3b	lipid phosphate phosphatase-related protein type 3b	0.010
snrnp40	small nuclear ribonucleoprotein 40 (U5)	0.010
rbm17	RNA binding motif protein 17	0.010
dldh	dihydrolipoamide dehydrogenase	0.010
snrpb	small nuclear ribonucleoprotein polypeptides B and B1	0.010