IMP

Process View

Danio rerio

11 genes annotated in zebrafish

regulation of cytoskeleton organization

Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in zebrafish Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cytoskeleton organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cytoskeleton organization" (in gray)

Name	Description	Probability	Func Analog Organism
bactin1	bactin1	0.556
nrp1a	neuropilin 1a	0.405
myhz2	myosin, heavy polypeptide 2, fast muscle specific	0.295	Mouse
itgb1b.2	integrin, beta 1b.2	0.282	Fly
kdrl	kinase insert domain receptor like	0.281
arpc5b	actin related protein 2/3 complex, subunit 5B	0.243	Human Worm
cotl1	coactosin-like 1 (Dictyostelium)	0.242
gng3	guanine nucleotide binding protein (G protein), gamma 3	0.233
smyd1b	SET and MYND domain containing 1b	0.221	Zebrafish
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.212
gnai2l	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like	0.208	Zebrafish
mfn2	mitofusin 2	0.191
nphs2	nephrosis 2, idiopathic, steroid-resistant (podocin)	0.164
acvr1b	activin A receptor, type IB	0.152
pdlim4	PDZ and LIM domain 4	0.131
ret1	receptor tyrosine kinase	0.126
ttk	ttk protein kinase	0.123	Yeast
ldb2a	LIM-domain binding factor 2a	0.106
esrrga	estrogen-related receptor gamma a	0.104
gna13b	guanine nucleotide binding protein (G protein), alpha 13b	0.101
ppp3cb	protein phosphatase 3, catalytic subunit, beta isozyme	0.098
gro2	groucho 2	0.097
pdlim2	PDZ and LIM domain 2 (mystique)	0.095
scinla	scinderin like a	0.091
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.091
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.084
plk1	polo-like kinase 1 (Drosophila)	0.080	Yeast
nusap1	nucleolar and spindle associated protein 1	0.077
flot2a	flotillin 2a	0.076
gna13a	guanine nucleotide binding protein (G protein), alpha 13a	0.075
marcksb	myristoylated alanine rich protein kinase C substrate b	0.074
LOC100151531	zinc finger protein Gfi-1b-like	0.074
met	met proto-oncogene (hepatocyte growth factor receptor)	0.069
csrp1a	cysteine and glycine-rich protein 1a	0.069
kif23	kinesin family member 23	0.068	Fly
nadl1.2	neural adhesion molecule L1.2	0.067
dusp6	dual specificity phosphatase 6	0.065
zgc:100942	zgc:100942	0.064	Zebrafish
mef2ca	myocyte enhancer factor 2ca	0.063	Mouse
wnt9a	wingless-type MMTV integration site family, member 9A	0.059
epb4.1l4	erythrocyte protein band 4.1-like 4	0.058
pnx	posterior neuron-specific homeobox	0.058
dscam	Down syndrome cell adhesion molecule	0.056
itgb1b	integrin, beta 1b	0.056	Fly
mef2a	myocyte enhancer factor 2a	0.055
tfr1a	transferrin receptor 1a	0.054
cdc42	cell division cycle 42	0.054	Human Fly
ttna	titin a	0.054
myl9l	myosin, light polypeptide 9, like	0.054
cep55l	centrosomal protein 55 like	0.052
zff9	zinc finger protein 9	0.051
zeb1	zinc finger E-box binding homeobox 1	0.051
kif14	kinesin family member 14	0.051
krt8	keratin 8	0.051
arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.050
hsp90a.1	heat shock protein 90-alpha 1	0.048
gata2a	GATA-binding protein 2a	0.048
snx12	sorting nexin 12	0.048
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.047	Fly
fras1	Fraser syndrome 1	0.047
pak2a	p21 (CDKN1A)-activated kinase 2a	0.046
wasb	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b	0.045	Worm Fly
ptk2.1	protein tyrosine kinase 2a	0.044
prickle1a	prickle-like 1 (Drosophila) a	0.044
nbl1	neuroblastoma, suppression of tumorigenicity 1	0.042
gpr126	G protein-coupled receptor 126	0.041
actn1	actinin, alpha 1	0.041
smyd1a	SET and MYND domain containing 1a	0.041	Zebrafish
ryr3	ryanodine receptor 3	0.041
wasa	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a	0.041	Worm Fly
capza1b	capping protein (actin filament) muscle Z-line, alpha 1b	0.041	Fly
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.041
sh3gl1b	SH3-domain GRB2-like 1b	0.041
f2r	coagulation factor II (thrombin) receptor	0.040
cdc20	cell division cycle 20 homolog	0.040
itgb1a	integrin, beta 1a	0.040	Fly
nccrp1	nonspecific cytotoxic cell receptor protein 1	0.039
vasn	vasorin	0.039
efnb2a	ephrin B2a	0.039
dtl	denticleless homolog (Drosophila)	0.039
zbtb4	zinc finger and BTB domain containing 4	0.039
zgc:136263	zgc:136263	0.038
sb:cb81	sb:cb81	0.038
flot1	flotillin 1	0.037
LOC100003330	melanocortin-2 receptor accessory protein 2-like	0.037
thy1	Thy-1 cell surface antigen	0.036
csf3r	colony stimulating factor 3 receptor (granulocyte)	0.036
myhz1.1	myosin, heavy polypeptide 1.1, skeletal muscle	0.036	Mouse
jam2a	junctional adhesion molecule 2a	0.035
stac3	SH3 and cysteine rich domain 3	0.034
btk	Bruton agammaglobulinemia tyrosine kinase	0.034	Fly
gle1	GLE1 RNA export mediator homolog (yeast)	0.034
fli1b	friend leukemia integration 1b	0.034
spns2	spinster homolog 2 (Drosophila)	0.034
ptger2a	prostaglandin E receptor 2a (subtype EP2)	0.034
tnnc1b	troponin C type 1b (slow)	0.034
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.033
zgc:100919	zgc:100919	0.033
rtcd1	RNA terminal phosphate cyclase domain 1	0.032
ptrfb	polymerase I and transcript release factor b	0.031
myl1	myosin, light chain 1, alkali; skeletal, fast	0.031
gna11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	0.031
zfyve26	zinc finger, FYVE domain containing 26	0.031
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.031	Fly
igfbp3	insulin-like growth factor binding protein 3	0.031
lama1	laminin, alpha 1	0.030
camk2g2	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2	0.030
pak1	p21/Cdc42/Rac1-activated kinase 1	0.029
g2e3	G2/M-phase specific E3 ubiquitin ligase	0.029
vegfc	vascular endothelial growth factor c	0.028
egr2b	early growth response 2b	0.028
si:ch211-69g19.2	si:ch211-69g19.2	0.027
fancd2	Fanconi anemia, complementation group D2	0.027
zgc:153063	zgc:153063	0.027
tuba1l	tubulin, alpha 1, like	0.026
hspg2	heparan sulfate proteoglycan 2	0.026
rbm22	RNA binding motif protein 22	0.026
pxn	paxillin	0.026
plxnb2a	plexin b2a	0.025
mylz2	myosin, light polypeptide 2, skeletal muscle	0.025
me2	malic enzyme 2, NAD(+)-dependent, mitochondrial	0.025
limk1	LIM domain kinase 1	0.025	Human Mouse
pfn1	profilin 1	0.025
klf2b	Kruppel-like factor 2b	0.024
sept2	septin 2	0.024
fcer1gl	Fc receptor, IgE, high affinity I, gamma polypeptide like	0.024
cyfip2	cytoplasmic FMR1 interacting protein 2	0.024
ccna2	cyclin A2	0.024
lims1	LIM and senescent cell antigen-like domains 1	0.024
rbl1	retinoblastoma-like 1 (p107)	0.023
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.023
itgb1b.1	integrin, beta 1b.1	0.023	Fly
itga5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.023	Fly
slit3	slit (Drosophila) homolog 3	0.023
LOC100536090	targeting protein for Xklp2-B-like	0.022
zgc:85866	zgc:85866	0.022
tbeta-a	beta thymosin-like protein 2	0.022
taf1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.022
mllt11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	0.022
sinup	siaz-interacting nuclear protein	0.022
shcbp1	SHC SH2-domain binding protein 1	0.022
tuba8l3	tubulin, alpha 8 like 3	0.022
myh10	myosin, heavy polypeptide 10, non-muscle and myosin, heavy chain 10, non-muscle	0.022
zgc:158327	zgc:158327	0.022
gnai3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	0.021
tpm3	tropomyosin 3	0.021	Worm
ezr	ezrin	0.021	Fly
atp1a3a	ATPase, Na+/K+ transporting, alpha 3a polypeptide	0.021
tubb5	tubulin, beta 5	0.021
zgc:153867	zgc:153867	0.021
ppargc1al	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like	0.020
ube2i2	ubiquitin-conjugating enzyme E2I2	0.020
zgc:92360	zgc:92360	0.020
si:ch211-156j22.4	si:ch211-156j22.4	0.020
fkbp4	FK506 binding protein 4	0.020	Rat
zgc:63831	zgc:63831	0.020
gngt2a	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a	0.020
gnas	GNAS complex locus	0.020
rnd1l	Rho family GTPase 1 like	0.020
foxm1	forkhead box M1	0.019
depdc1a	DEP domain containing 1a	0.019
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.019
epor	erythropoietin receptor	0.019
xirp1	xin actin-binding repeat containing 1	0.019
llgl2	lethal giant larvae homolog 2 (Drosophila)	0.019
actr3	ARP3 actin-related protein 3 homolog (yeast)	0.018
rorcb	RAR-related orphan receptor C b	0.018
ncapg2	non-SMC condensin II complex, subunit G2	0.018
ctnnb1	catenin (cadherin-associated protein), beta 1	0.018	Human Worm
igfbp1a	insulin-like growth factor binding protein 1a	0.018
fgf20a	fibroblast growth factor 20a	0.017
s100a10a	S100 calcium binding protein A10a	0.017	Human
zgc:152925	zgc:152925	0.017
ticrr	TopBP1-interacting, checkpoint, and replication regulator	0.017
zgc:153369	zgc:153369	0.017
lndc1	ly6/neurotoxin domain containing 1	0.017
arpc5a	actin related protein 2/3 complex, subunit 5A	0.017
elk4	ELK4, ETS-domain protein	0.017
atp6v1b2	ATPase, H+ transporting, lysosomal V1 subunit B2	0.017
celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.017
esrrb	estrogen-related receptor beta	0.017
lasp1	LIM and SH3 protein 1	0.017
lbx2	ladybird homeobox homolog 2 (Drosophila)	0.017
casz1	castor zinc finger 1	0.017
nfasca	neurofascin homolog (chicken) a	0.017
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.017
acta1b	actin, alpha 1b, skeletal muscle	0.016
ezh2	enhancer of zeste homolog 2 (Drosophila)	0.016
wdr1	WD repeat domain 1	0.016
col5a3b	collagen type V alpha-3b	0.016
tp63	tumor protein p63	0.016
col14a1	collagen, type XIV, alpha 1	0.016
ints6	integrator complex subunit 6	0.016
esr2b	estrogen receptor 2b	0.016
mpll	myeloproliferative leukemia virus oncogene, like	0.016
gmfg	glia maturation factor, gamma	0.016
cfl1	cofilin 1 (non-muscle)	0.016	Mouse
gpt2	glutamic pyruvate transaminase (alanine aminotransferase) 2	0.016
irf6	interferon regulatory factor 6	0.016
sh3bgrl3	SH3 domain binding glutamic acid-rich protein like 3	0.016
zgc:165373	zgc:165373	0.016
mmp9	matrix metalloproteinase 9	0.015
LOC566969	similar to MOX-2 protein	0.015
slc8a4a	solute carrier family 8 (sodium/calcium exchanger), member 4a	0.015
mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.015
pkp2	plakophilin 2	0.015	Worm
bhlhe41	basic helix-loop-helix family, member e41	0.015
gnat2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.015	Zebrafish
robo2	roundabout homolog 2	0.015
satb2	SATB homeobox 2	0.015
f2rl1.1	coagulation factor II (thrombin) receptor-like 1.1	0.014	Human
chat	choline acetyltransferase	0.014
arpc4	actin related protein 2/3 complex, subunit 4	0.014
rrp12	ribosomal RNA processing 12 homolog (S. cerevisiae)	0.014
si:ch211-197n10.2	si:ch211-197n10.2	0.014
cap1	Cap1 CAP, adenylate cyclase-associated protein 1	0.014
fibpl	fibroblast growth factor (acidic) intracellular binding protein, like	0.014
meox2a	mesenchyme homeobox 2a	0.014
nadl1.1	neural adhesion molecule L1.1	0.014
rhpn2	rhophilin, Rho GTPase binding protein 2	0.014
tnrc5	trinucleotide repeat containing 5	0.014
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.014
jup	junction plakoglobin	0.014
birc5a	baculoviral IAP repeat-containing 5a	0.014
inhbb	inhibin, beta B	0.014
arpc4l	actin related protein 2/3 complex, subunit 4, like	0.013
cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.013
si:ch211-244o22.2	si:ch211-244o22.2	0.013
dmrt2b	doublesex and mab-3 related transcription factor 2b	0.013
LOC556160	guanine nucleotide-binding protein subunit alpha-14-like	0.013
tnnt3b	troponin T3b, skeletal, fast	0.013
per3	period homolog 3 (Drosophila)	0.013
cltca	clathrin, heavy polypeptide a (Hc)	0.013
si:ch73-60e21.1	si:ch73-60e21.1	0.013
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.013
tnnt1	troponin T1, skeletal, slow	0.013
pcdh10a	protocadherin 10a	0.013
rab5c	RAB5C, member RAS oncogene family	0.013
senp6a	SUMO1/sentrin specific peptidase 6a	0.013
ptges	prostaglandin E synthase	0.013
syt5a	synaptotagmin Va	0.013
rras	related RAS viral (r-ras) oncogene homolog	0.013
nos1	nitric oxide synthase 1 (neuronal)	0.013
tnfaip8l2b	tumor necrosis factor, alpha-induced protein 8, like 2b	0.013
mta2	metastasis associated 1 family, member 2	0.012
ptpra	protein tyrosine phosphatase, receptor type, A	0.012
dpysl5a	dihydropyrimidinase-like 5a	0.012
musk	muscle, skeletal, receptor tyrosine kinase	0.012
rdh8l	retinol dehydrogenase 8 like	0.012
ptprc	protein tyrosine phosphatase, receptor type, C	0.012
h1m	linker histone H1M	0.012
ucp2	uncoupling protein 2	0.012
zgc:55557	zgc:55557	0.012
actn3b	actinin alpha 3b	0.012
crfb5	cytokine receptor family member b5	0.012
ap1s2	adaptor-related protein complex 1, sigma 2 subunit	0.012
zgc:101761	zgc:101761	0.012
LOC100149148	novel protein similar to myosin heavy chain 4 (myhc4)	0.012
neb	nebulin	0.012
pdlim1	PDZ and LIM domain 1 (elfin)	0.012
anxa2a	annexin A2a	0.012
fam49ba	family with sequence similarity 49, member Ba	0.012
ogt.1	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1	0.012
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.012
camk2g1	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1	0.012
nt5e	5'-nucleotidase, ecto (CD73)	0.012
zgc:66317	zgc:66317	0.012
LOC100331639	hypothetical protein LOC100331639	0.012
coro1a	coronin, actin binding protein, 1A	0.011	Human Mouse
prkcz	protein kinase C, zeta	0.011
htra1a	HtrA serine peptidase 1a	0.011
dixdc1a	DIX domain containing 1a	0.011
lrrc33	leucine rich repeat containing 33	0.011
capn9	calpain 9	0.011
hhatla	hedgehog acyltransferase-like, a	0.011
hspb8	heat shock protein, alpha-crystallin-related, b8	0.011
ids	iduronate 2-sulfatase	0.011
irx3a	iroquois homeobox protein 3a	0.011
pitx3	paired-like homeodomain transcription factor 3	0.011
vegfaa	vascular endothelial growth factor Aa	0.011
sema3ab	semaphorin 3ab	0.011	Worm
chac1	ChaC, cation transport regulator-like 1	0.011
slc1a2b	solute carrier family 1 (glial high affinity glutamate transporter), member 2b	0.011
foxo3b	forkhead box O3b	0.011
lztfl1	leucine zipper transcription factor-like 1	0.011
popdc1	popeye domain containing 1	0.011
myod1	myogenic differentiation 1	0.011
zgc:64051	zgc:64051	0.011
apobec2a	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a	0.011
celsr1b	cadherin EGF LAG seven-pass G-type receptor 1b	0.011	Mouse
apoeb	apolipoprotein Eb	0.011
ckap5	cytoskeleton associated protein 5	0.011
dlg4	discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)	0.011
entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.011
zgc:66286	zgc:66286	0.011
LOC566708	FL cytokine receptor-like	0.011
twf1a	twinfilin, actin-binding protein, homolog 1a	0.011
dopey1	dopey family member 1	0.011
snrk1	SNF related kinase 1	0.011
hn1l	hematological and neurological expressed 1-like	0.011
smad2	MAD homolog 2 (Drosophila)	0.011
top2b	topoisomerase (DNA) II beta	0.011
pvrl1b	poliovirus receptor-related 1b	0.011
pdlim5	PDZ and LIM domain 5	0.011
acss2	acyl-CoA synthetase short-chain family member 2	0.011
fbl	fibrillarin	0.010
gngt1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.010
LOC560606	novel protein similar to human and mouse leishmanolysin-like (metallopeptidase M8 family) (LMLN)	0.010
sulf2l	sulfatase 2, like	0.010
ccnb2	cyclin B2	0.010	Yeast
sec24d	SEC24 family, member D (S. cerevisiae)	0.010
tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.010
cnot6	CCR4-NOT transcription complex, subunit 6	0.010
utp11l	UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)	0.010
lhx2b	LIM homeobox 2b	0.010
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.010
ift46	intraflagellar transport protein 46	0.010