IMP

Process View

Danio rerio

3 genes annotated in zebrafish

hatching gland development

The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hatching gland development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "hatching gland development" (in gray)

Name	Description	Probability	Func Analog Organism
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.617
foxa1	forkhead box A1	0.583	Zebrafish
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.475
foxa2	forkhead box A2	0.454	Zebrafish
foxa3	forkhead box A3	0.425
foxi1	forkhead box I1	0.382	Zebrafish
foxi3b	forkhead box I3b	0.369	Zebrafish
tfe3b	transcription factor binding to IGHM enhancer 3b	0.352
sox10	SRY-box containing gene 10	0.329
tp63	tumor protein p63	0.314
inka1a	induced in neural crest by AP2, 1a	0.249
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.227
eya1	eyes absent homolog 1	0.219
foxi3a	forkhead box I3a	0.198	Zebrafish
sox2	SRY-box containing gene 2	0.167
sox19a	SRY-box containing gene 19a	0.164
tfec	transcription factor EC	0.163
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.154
fsta	follistatin a	0.154
gsc	goosecoid	0.136
ntla	no tail a	0.133
jag1b	jagged 1b	0.131
six4b	sine oculis homeobox homolog 4b	0.117
foxb1.1	forkhead box B1.1	0.117	Zebrafish
flh	floating head	0.113
slc4a1a	solute carrier family 4, anion exchanger, member 1a	0.103
nkx2.3	NK2 transcription factor related 3	0.102
zgc:194131	zgc:194131	0.097
edn1	endothelin 1	0.096
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.093
pitx2	paired-like homeodomain transcription factor 2	0.092
aldob	aldolase b, fructose-bisphosphate	0.091
nkx2.2b	NK2 transcription factor related 2b	0.087
mid1ip1b	MID1 interacting protein 1b	0.085
gbx2	gastrulation brain homeo box 2	0.085
bmper	BMP binding endothelial regulator	0.079
alas2	aminolevulinate, delta-, synthetase 2	0.078
slc12a10.2	solute carrier family 12 (sodium/potassium/chloride transporters), member 10.2	0.078
vasn	vasorin	0.075
nt5c2l1	5'-nucleotidase, cytosolic II, like 1	0.075
dnmt6	DNA (cytosine-5-)-methyltransferase 6	0.074
hmx4	H6 family homeobox 4	0.074
col9a3	collagen, type IX, alpha 3	0.072
bhlhe22	basic helix-loop-helix family, member e22	0.069
dlc	deltaC	0.068
adipoql	adiponectin, C1Q and collagen domain containing, like	0.065
slc4a1b	solute carrier family 4, anion exchanger, member 1b	0.065
irx1b	iroquois homeobox protein 1, b	0.061
hbbe2	hemoglobin beta embryonic-2	0.059
six3b	sine oculis homeobox homolog 3b	0.058
grhl1	grainyhead-like 1 (Drosophila)	0.057
pdgfaa	platelet-derived growth factor alpha a	0.057
nadka	NAD kinase a	0.056
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.053
nog1	noggin 1	0.052
hhex	hematopoietically expressed homeobox	0.052
dao.2	D-amino-acid oxidase 2	0.049
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.048
hoxb3a	homeo box B3a	0.047
kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.047
sfrp1b	secreted frizzled-related protein 1b	0.045
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.045
lhx5	LIM homeobox 5	0.045
tyrp1b	tyrosinase-related protein 1b	0.044
adipor2	adiponectin receptor 2	0.044
vwf	von Willebrand factor	0.043
guk1	guanylate kinase 1	0.041
sp5l	Sp5 transcription factor-like	0.040
slc7a6	solute carrier family 7 (cationic amino acid transporter, y+ system), member 6	0.039
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.039
gcm2	glial cells missing homolog 2 (Drosophila)	0.039
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.037
prdm1a	PR domain containing 1a, with ZNF domain	0.037
itgb6	integrin, beta 6	0.036
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.035
mab21l2	mab-21-like 2	0.034
rxrga	retinoid x receptor, gamma a	0.034
ctsl1b	cathepsin L, 1 b	0.033
gata3	GATA-binding protein 3	0.033
grhl2b	grainyhead-like 2b (Drosophila)	0.033
hdr	hematopoietic death receptor	0.032
zic6	zic family member 6	0.031
junb	jun B proto-oncogene	0.031
foxc1a	forkhead box C1a	0.030
si:dkey-145p14.5	si:dkey-145p14.5	0.030
hesx1	homeo box (expressed in ES cells) 1	0.030
kctd15a	potassium channel tetramerisation domain containing 15a	0.030
col9a1	collagen, type IX, alpha 1	0.030
her3	hairy-related 3	0.029
msxb	muscle segment homeobox B	0.029
evla	Enah/Vasp-like a	0.028
atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.027
hlxb9la	homeo box HB9 like a	0.027
pax4	paired box 4	0.027
vat1	vesicle amine transport protein 1 homolog (T californica)	0.026
met	met proto-oncogene (hepatocyte growth factor receptor)	0.026
nkx2.1b	NK2 homeobox 1b	0.026
nkx6.2	NK6 transcription factor related, locus 2	0.026
zgc:114181	zgc:114181	0.026
klhl31	kelch-like 31 (Drosophila)	0.026
sepp1b	selenoprotein P, plasma, 1b	0.025
arhgap29a	Rho GTPase activating protein 29a	0.025
nkx2.9	NK2 transcription factor related, locus 9 (Drosophila)	0.025
slit1b	slit homolog 1b (Drosophila)	0.025
pppde2a	PPPDE peptidase domain containing 2a	0.025
sptb	spectrin, beta, erythrocytic	0.024
vsx2	visual system homeobox 2	0.023
spi1l	spleen focus forming virus (SFFV) proviral integration oncogene spi1 like	0.023
zic2b	zic family member 2 (odd-paired homolog, Drosophila) b	0.023
zgc:153997	zgc:153997	0.023
slc13a3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.023
jak2a	Janus kinase 2a	0.023
cdx4	caudal type homeo box transcription factor 4	0.023
klf2a	Kruppel-like factor 2a	0.022
pcdh19	protocadherin 19	0.022
mxtx1	mix-type homeobox gene 1	0.022
ugcg	UDP-glucose ceramide glucosyltransferase	0.022
cart1	cartilage paired-class homeoprotein 1	0.022
fgf13b	fibroblast growth factor 13b	0.021
sh2d3cb	SH2 domain containing 3Cb	0.021
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.021
hmx3	homeo box (H6 family) 3	0.021
slc4a4b	solute carrier family 4, sodium bicarbonate cotransporter, member 4b	0.021
gata2a	GATA-binding protein 2a	0.021
atp1b1b	ATPase, Na+/K+ transporting, beta 1b polypeptide	0.021
sox1a	SRY-box containing gene 1a	0.020
otx1b	orthodenticle homolog 1b	0.020
raraa	retinoic acid receptor, alpha a	0.020
si:dkey-110c1.1	si:dkey-110c1.1	0.020
dapp1	dual adaptor of phosphotyrosine and 3-phosphoinositides	0.020
itih2	inter-alpha (globulin) inhibitor H2	0.020
ctsba	cathepsin B, a	0.020
id:ibd1125	id:ibd1125	0.020
fbp1b	fructose-1,6-bisphosphatase 1b	0.020
dusp5	dual specificity phosphatase 5	0.020
cdx1b	caudal type homeobox 1 b	0.020
cldn5a	claudin 5a	0.019
tfa	transferrin-a	0.019
si:dkeyp-51f12.4	si:dkeyp-51f12.4	0.019
pdgfab	platelet derived growth factor alpha b	0.019
zgc:162939	zgc:162939	0.019
blf	bloody fingers	0.019
ctgf	connective tissue growth factor	0.019
nrip1b	nuclear receptor interacting protein 1b	0.019
si:dkey-177e13.4	si:dkey-177e13.4	0.018
foxg1a	forkhead box G1a	0.018	Zebrafish
fgf3	fibroblast growth factor 3	0.018
pitx1	paired-like homeodomain transcription factor 1	0.018
plk2b	polo-like kinase 2b (Drosophila)	0.018
drgx	dorsal root ganglia homeobox	0.018
adipoql2	adiponectin, C1Q and collagen domain containing, like 2	0.018
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.018
epha2	eph receptor A2	0.018
dusp7	dual specificity phosphatase 7	0.018
tmem22	transmembrane protein 22	0.017
rhag	Rhesus blood group-associated glycoprotein	0.017
cldn5b	claudin 5b	0.017
zgc:66382	zgc:66382	0.017
wif1	wnt inhibitory factor 1	0.017
id3	inhibitor of DNA binding 3	0.017
si:dkeyp-66d7.2	si:dkeyp-66d7.2	0.017
pim1	pim-1 oncogene	0.017
defbl1	defensin, beta-like 1	0.017
ulk2	unc-51-like kinase 2 (C. elegans)	0.017
hoxb5a	homeo box B5a	0.017
rlbp1a	retinaldehyde binding protein 1a	0.016
coro2a	coronin, actin binding protein, 2A	0.016
carm1	coactivator-associated arginine methyltransferase 1	0.016
eya2	eyes absent homolog 2 (Drosophila)	0.016
cyt1	type I cytokeratin, enveloping layer	0.016
foxi2	forkhead box I2	0.016	Zebrafish
cldn11a	claudin 11a	0.016
tkt	transketolase	0.016
esrrd	estrogen-related receptor delta	0.016
foxd3	forkhead box D3	0.016	Zebrafish
vtnb	vitronectin b	0.016
stat3	signal transduction and activation of transcription 3	0.016
vsg1	vessel-specific 1	0.016
c10orf11	c10orf11 homolog (H. sapiens)	0.015
bhlha15	basic helix-loop-helix family, member a15	0.015
lgr8.2	hypothetical LOC566888	0.015
og9x	OG9 homeobox gene	0.015
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.015
blvrb	biliverdin reductase B (flavin reductase (NADPH))	0.015
atf3	activating transcription factor 3	0.015
rfx6	regulatory factor X, 6	0.015
zgc:91968	zgc:91968	0.015
psap	prosaposin	0.015
cap1	Cap1 CAP, adenylate cyclase-associated protein 1	0.015
socs3b	suppressor of cytokine signaling 3b	0.015
si:dkeyp-51f11.8	si:dkeyp-51f11.8	0.015
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.015
hbegfa	heparin-binding EGF-like growth factor a	0.014
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.014
msgn1	mesogenin 1	0.014
gadd45ba	growth arrest and DNA-damage-inducible, beta a	0.014
cd248a	CD248 molecule, endosialin a	0.014
spns2	spinster homolog 2 (Drosophila)	0.014
c9	complement component 9	0.014
id:ibd2031	id:ibd2031	0.014
chmp1a	chromatin modifying protein 1A	0.014
grin2da	glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a	0.014
si:busm1-57f23.1	si:busm1-57f23.1	0.014
ak5l	adenylate kinase 5, like	0.014
cyp26a1	cytochrome P450, subfamily XXVIA, polypeptide 1	0.014
cga	glycoprotein hormones, alpha polypeptide	0.014
rab11fip4a	RAB11 family interacting protein 4 (class II) a	0.014
zgc:110340	zgc:110340	0.014
dao.1	D-amino-acid oxidase 1	0.014
mavs	mitochondrial antiviral signaling protein	0.014
LOC559157	contactin-associated protein-like 2-like	0.014
zgc:66441	zgc:66441	0.014
ets2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.014
ek1	eph-like kinase 1	0.013
sc:d411	sc:d411	0.013
zgc:85942	zgc:85942	0.013
ptprb	protein tyrosine phosphatase, receptor type, b	0.013
aqp1a.1	aquaporin 1a, tandem duplicate 1	0.013
im:7152348	im:7152348	0.013
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.013
tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.013
alad	aminolevulinate dehydratase	0.013
sncga	synuclein, gamma a	0.013
im:7138016	im:7138016	0.013
pdia2	protein disulfide isomerase family A, member 2	0.013
mat2a	methionine adenosyltransferase II, alpha	0.013
grap	GRB2-related adaptor protein	0.013
tlx3b	T-cell leukemia, homeobox 3b	0.013
slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.013
six3a	sine oculis homeobox homolog 3a	0.013
si:dkey-233h2.3	si:dkey-233h2.3	0.013
rarab	retinoic acid receptor, alpha b	0.013
foxo1a	forkhead box O1 a	0.013
zgc:153096	zgc:153096	0.013
si:dkeyp-27b10.2	si:dkeyp-27b10.2	0.013
zgc:161979	zgc:161979	0.013
cdkrap3	CDK5 regulatory subunit associated protein 3	0.013
ncf1	neutrophil cytosolic factor 1	0.013
clec14a	C-type lectin domain family 14, member A	0.013
pmelb	premelanosome protein b	0.013
hprt1	hypoxanthine phosphoribosyltransferase 1	0.012
ca15a	carbonic anhydrase XV a	0.012
pou1f1	POU domain, class 1, transcription factor 1	0.012
slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.012
si:dkey-13a21.4	si:dkey-13a21.4	0.012
caspa	caspase a	0.012
caspb	caspase b and caspase b-like	0.012
metrn	meteorin, glial cell differentiation regulator	0.012
LOC100151531	zinc finger protein Gfi-1b-like	0.012
mmp13a	matrix metalloproteinase 13a	0.012
chac1	ChaC, cation transport regulator-like 1	0.012
f13a1	coagulation factor XIII, A1 polypeptide	0.012
xbp1	X-box binding protein 1	0.012
nfe2l1	nuclear factor, erythroid derived 2,-like 1	0.012
rps6ka3a	ribosomal protein S6 kinase, polypeptide 3a	0.012
rorab	RAR-related orphan receptor A, paralog b	0.012
rhd	Rh blood group, D antigen	0.012
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.012
irx7	iroquois homeobox protein 7	0.012
emilin3a	elastin microfibril interfacer 3a	0.012
slc16a9a	solute carrier family 16 (monocarboxylic acid transporters), member 9a	0.012
fgd4	FYVE, RhoGEF and PH domain containing 4	0.012
rab5c	RAB5C, member RAS oncogene family	0.012
ap1g1	adaptor-related protein complex 1, gamma 1 subunit	0.012
zswim6	zinc finger, SWIM-type containing 6	0.012
adipor1b	adiponectin receptor 1b	0.012
coro1ca	coronin, actin binding protein, 1Ca	0.012
slc20a1a	solute carrier family 20, member 1a	0.012
cd164	CD164 molecule, sialomucin	0.011
arg2	arginase, type II	0.011
alx4b	aristaless-like homeobox 4b	0.011
olfm1a	olfactomedin 1a	0.011
dip2ba	DIP2 disco-interacting protein 2 homolog Ba (Drosophila)	0.011
nr1i2	nuclear receptor subfamily 1, group I, member 2	0.011
id:ibd2808	id:ibd2808	0.011
zgc:66433	zgc:66433	0.011
tshr	thyroid stimulating hormone receptor	0.011
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.011
si:dkey-3d4.3	si:dkey-3d4.3	0.011
pabpc1b	poly A binding protein, cytoplasmic 1 b	0.011
otx2	orthodenticle homolog 2	0.011
junbl	jun B proto-oncogene, like	0.011
atoh7	atonal homolog 7	0.011
ndrg1l	N-myc downstream regulated gene 1, like	0.011
tpt1	tumor protein, translationally-controlled 1	0.011
insl5b	insulin-like 5b	0.011
lrtm2	leucine-rich repeats and transmembrane domains 2	0.011
neurod6a	neurogenic differentiation 6a	0.011
zgc:92481	zgc:92481	0.011
si:dkeyp-115d2.5	si:dkeyp-115d2.5	0.011
f2rl1.1	coagulation factor II (thrombin) receptor-like 1.1	0.011
f8	coagulation factor VIII, procoagulant component	0.011
id:ibd2050	id:ibd2050	0.011
rwdd3	RWD domain containing 3	0.011
pax3b	paired box gene 3b	0.011
hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.011
foxf1	forkhead box F1	0.011
id:ibd2573	id:ibd2573	0.011
gadd45bb	growth arrest and DNA-damage-inducible, beta b	0.011
plod2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.011
otol1a	otolin 1a	0.011
nrg1	neuregulin 1	0.011
dusp4	dual specificity phosphatase 4	0.011
si:ch211-154o6.4	si:ch211-154o6.4	0.010
lats1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.010
col4a3bpa	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a	0.010
irg1l	immunoresponsive gene 1, like	0.010
si:dkey-25e12.5	si:dkey-25e12.5	0.010
hgfb	hepatocyte growth factor b	0.010
faf1	Fas associated factor 1	0.010
id:ibd5149	id:ibd5149	0.010
sv2b	synaptic vesicle glycoprotein 2 b	0.010
aldh1a3	aldehyde dehydrogenase 1 family, member A3	0.010
drd4-rs	dopamine receptor D4 related sequence	0.010
efna3b	ephrin A3b	0.010
tbr1b	T-box, brain, 1b	0.010
vlk	vertebrate lonesome kinase	0.010
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.010
cacnb3b	calcium channel, voltage-dependent, beta 3b	0.010
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.010
si:ch211-268m12.5	si:ch211-268m12.5	0.010
slc2a1a	solute carrier family 2 (facilitated glucose transporter), member 1a	0.010
cabp1	calcium binding protein 1	0.010
cldna	claudin a	0.010
pmp22b	peripheral myelin protein 22b	0.010
socs3a	suppressor of cytokine signaling 3a	0.010
bcl6a	B-cell CLL/lymphoma 6a (zinc finger protein 51)	0.010