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Danio rerio

11 genes annotated in zebrafish

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negative regulation of embryonic development

GO:0045992

Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of embryonic development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of embryonic development" (in gray)

Name	Description	Probability	Func Analog Organism
chd	chordin	0.779
bmp2b	bone morphogenetic protein 2b	0.729
notch2	notch homolog 2	0.632
dkk1b	dickkopf 1b	0.520
dlx5a	distal-less homeobox gene 5a	0.364
foxi1	forkhead box I1	0.342
mespa	mesoderm posterior a	0.330	Mouse
foxa3	forkhead box A3	0.322
sox32	SRY-box containing gene 32	0.318	Mouse
hmx4	H6 family homeobox 4	0.277
hhip	hedgehog interacting protein	0.263
foxd5	forkhead box D5	0.225
wnt11r	wingless-type MMTV integration site family, member 11, related	0.221
bmp4	bone morphogenetic protein 4	0.219
nog1	noggin 1	0.184
frem3	Fras1 related extracellular matrix 3	0.181
tbx6	T-box gene 6	0.181
sfrp1a	secreted frizzled-related protein 1a	0.137
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.137
wif1	wnt inhibitory factor 1	0.133
gli1	GLI-Kruppel family member 1	0.130
pcdh8	protocadherin 8	0.127
gbx2	gastrulation brain homeo box 2	0.120
col14a1	collagen, type XIV, alpha 1	0.119
hbbe2	hemoglobin beta embryonic-2	0.117
lama5	laminin, alpha 5	0.106
aldh1a3	aldehyde dehydrogenase 1 family, member A3	0.099
fzd7a	frizzled homolog 7a	0.096
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.094
alas2	aminolevulinate, delta-, synthetase 2	0.091
tp63	tumor protein p63	0.076
sparc	secreted acidic cysteine rich glycoprotein	0.071
fstl1b	follistatin-like 1b	0.069
msxc	muscle segment homeobox C	0.064
fgf17	fibroblast growth factor 17	0.063
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.062
mespb	mesoderm posterior b	0.060	Mouse
ctgf	connective tissue growth factor	0.057
gata2a	GATA-binding protein 2a	0.057
hoxa2b	homeo box A2b	0.054
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.053
hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.053
stm	starmaker	0.052
frzb	frizzled-related protein	0.052
fgf3	fibroblast growth factor 3	0.052
dcn	decorin	0.050
fgfrl1a	fibroblast growth factor receptor-like 1a	0.049
lft1	lefty1	0.048
sptb	spectrin, beta, erythrocytic	0.046
fgf8a	fibroblast growth factor 8 a	0.045
wnt9a	wingless-type MMTV integration site family, member 9A	0.045
fgf10a	fibroblast growth factor 10a	0.044
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.043
tbx1	T-box 1	0.043
fras1	Fraser syndrome 1	0.043
has2	hyaluronan synthase 2	0.042
sox11b	SRY-box containing gene 11b	0.041
wnt5b	wingless-type MMTV integration site family, member 5b	0.041	Mouse
grem2	gremlin 2, cysteine knot superfamily	0.040
nrarpa	notch-regulated ankyrin repeat protein a	0.039
wu:fv91b12	wu:fv91b12	0.039
shha	sonic hedgehog a	0.036
vsx2	visual system homeobox 2	0.035	Zebrafish
ndr2	nodal-related 2	0.035
nt5c2l1	5'-nucleotidase, cytosolic II, like 1	0.034
sesn1	sestrin 1	0.034
dharma	dharma	0.034
nkx2.2b	NK2 transcription factor related 2b	0.034
fgfr1a	fibroblast growth factor receptor 1a	0.033
tll1	tolloid-like 1	0.033
ripply1	ripply1	0.033
vgll4l	vestigial like 4 like	0.032
aplnra	apelin receptor a	0.032
smad5	MAD homolog 5 (Drosophila)	0.032
pitx3	paired-like homeodomain transcription factor 3	0.032
hmx1	H6 homeo box 1	0.031
tbx16	T-box gene 16	0.030
sox17	SRY-box containing gene 17	0.029	Mouse
hesx1	homeo box (expressed in ES cells) 1	0.028
her5	hairy-related 5	0.028
rasl11b	RAS-like, family 11, member B	0.028
flh	floating head	0.027
rxrga	retinoid x receptor, gamma a	0.027
lft2	lefty2	0.027
bmp1a	bone morphogenetic protein 1a	0.027
bmper	BMP binding endothelial regulator	0.026
wnt10a	wingless-type MMTV integration site family, member 10a	0.026
dlx4b	distal-less homeobox gene 4b	0.026
dmrt3a	doublesex and mab-3 related transcription factor 3a	0.025
irf6	interferon regulatory factor 6	0.025
klf4	Kruppel-like factor 4	0.025	Zebrafish
fbn2b	fibrillin 2b	0.025
apoeb	apolipoprotein Eb	0.025
otx1a	orthodenticle homolog 1a	0.025
ext1a	exostoses (multiple) 1a	0.024
col11a1a	collagen, type XI, alpha 1a	0.023
slc4a1a	solute carrier family 4, anion exchanger, member 1a	0.023
eve1	even-skipped-like1	0.023
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.022
ntn2	netrin 2	0.022
col1a2	collagen, type I, alpha 2	0.021
col7a1l	collagen type VII alpha 1-like	0.021
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.021
spon1b	spondin 1b	0.021
celf1	cugbp, Elav-like family member 1	0.021
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.021
epha4b	eph receptor A4b	0.021
fgf8b	fibroblast growth factor 8 b	0.021	Zebrafish
jag1b	jagged 1b	0.021
hgfa	hepatocyte growth factor a	0.021
nanos3	nanos homolog 3	0.020
fn1	fibronectin 1	0.020
fbln1	fibulin 1	0.020
vent	ventral expressed homeobox	0.020
sfrp2	secreted frizzled-related protein 2	0.019	Mouse
or115-10	odorant receptor, family F, subfamily 115, member 10	0.019
zgc:85866	zgc:85866	0.019
vasp	vasodilator-stimulated phosphoprotein	0.019
runx3	runt-related transcription factor 3	0.019
gpr126	G protein-coupled receptor 126	0.019
efna5a	ephrin A5a	0.018
evx1	even-skipped homeobox 1	0.018
tagln2	transgelin 2	0.018
vcana	versican a	0.018
thbs4b	thrombospondin 4b	0.018
acvr1b	activin A receptor, type IB	0.017
tbx2b	T-box 2b	0.017
etv5b	ets variant 5b	0.017
ntn1b	netrin 1b	0.017
ved	ventrally expressed dharma/bozozok antagonist	0.017
her1	hairy-related 1	0.016
ripply2	ripply2	0.016
col1a1a	collagen, type I, alpha 1a	0.016
dab1a	disabled homolog 1a (Drosophila)	0.016
tal1	T-cell acute lymphocytic leukemia 1	0.016
edn1	endothelin 1	0.016
zgc:77051	zgc:77051	0.016
sox9b	SRY-box containing gene 9b	0.015
foxa1	forkhead box A1	0.015
ncs1a	neuronal calcium sensor 1a	0.015
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.015
zgc:55877	zgc:55877	0.015
twist3	twist3	0.015
onecutl	one cut domain, family member, like	0.015
ryk	receptor-like tyrosine kinase	0.015
lamb1a	laminin, beta 1a	0.015
gucy2f	guanylate cyclase 2F, retinal	0.015
zgc:158603	zgc:158603	0.015
egfl6	EGF-like-domain, multiple 6	0.015
sim1a	single-minded homolog 1a (Drosophila)	0.014
ephb3a	eph receptor B3a	0.014
cdh2	cadherin 2, neuronal	0.014
si:ch211-173o4.2	si:ch211-173o4.2	0.014
LOC567678	avidin-like	0.014
LOC100000500	sclerostin-like	0.014
msxd	muscle segment homeobox D	0.014
fgfr1b	fibroblast growth factor receptor 1b	0.014	Zebrafish
igf3	insulin-like growth factor 3	0.014
rhoub	ras homolog gene family, member Ub	0.014
nkx2.2a	NK2 transcription factor related 2a	0.014
hmx3	homeo box (H6 family) 3	0.014
frem2a	Fras1 related extracellular matrix protein 2a	0.013
tjp1	tight junction protein 1 (zona occludens 1)	0.013
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.013
dazl	daz-like gene	0.013
rbm39a	RNA binding motif protein 39a	0.013
wnt2	wingless-type MMTV integration site family member 2	0.013
bmp2a	bone morphogenetic protein 2a	0.013	Zebrafish
hdr	hematopoietic death receptor	0.013
hoxa11a	homeo box A11a	0.013
atp1a1a.5	ATPase, Na+/K+ transporting, alpha 1a.5 polypeptide	0.012
col1a1b	collagen, type I, alpha 1b	0.012
inka1a	induced in neural crest by AP2, 1a	0.012
cyt1	type I cytokeratin, enveloping layer	0.012
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.012
hapln3	hyaluronan and proteoglycan link protein 3	0.012
twist1a	twist1a	0.012
spns2	spinster homolog 2 (Drosophila)	0.012
epha7	eph receptor A7	0.012
vox	ventral homeobox	0.012
prtga	protogenin homolog a (Gallus gallus)	0.012
notch3	notch homolog 3	0.012
col5a2l	collagen, type V, alpha 2-like	0.011	Human
col8a1a	collagen, type VIII, alpha 1a	0.011
uts2a	urotensin 2, alpha	0.010
thbs1	thrombospondin 1	0.010
trpc1	transient receptor potential cation channel, subfamily C, member 1	0.010
dusp6	dual specificity phosphatase 6	0.010
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.010
zgc:73328	zgc:73328	0.010