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Danio rerio

5 genes annotated in zebrafish

respiratory system development

The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "respiratory system development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "respiratory system development" (in gray)

Name	Description	Probability	Func Analog Organism
shha	sonic hedgehog a	0.616	Mouse Fly
notch1a	notch homolog 1a	0.529	Mouse Fly
foxa3	forkhead box A3	0.273	Zebrafish
mib	mind bomb	0.243
eya1	eyes absent homolog 1	0.236	Mouse
pitx3	paired-like homeodomain transcription factor 3	0.233
tfe3b	transcription factor binding to IGHM enhancer 3b	0.231
twist1a	twist1a	0.214
pax2a	paired box gene 2a	0.156
jag1b	jagged 1b	0.132
notch3	notch homolog 3	0.132	Fly
foxi1	forkhead box I1	0.131	Zebrafish
fgfr2	fibroblast growth factor receptor 2	0.121	Mouse Fly
wls	wntless homolog (Drosophila)	0.115
satb2	SATB homeobox 2	0.097
fgf10a	fibroblast growth factor 10a	0.094	Mouse
wt1b	wilms tumor 1b	0.076	Mouse
atp1b1b	ATPase, Na+/K+ transporting, beta 1b polypeptide	0.076
sulf1	sulfatase 1	0.071
bmp4	bone morphogenetic protein 4	0.067	Human Mouse Rat Fly
six4b	sine oculis homeobox homolog 4b	0.064	Mouse
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.063
fgf3	fibroblast growth factor 3	0.063
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.063
gata6	GATA-binding protein 6	0.058
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.057	Mouse
sox9b	SRY-box containing gene 9b	0.056
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.054
tp53	tumor protein p53	0.049
foxj1b	forkhead box J1b	0.047
kif17	kinesin family member 17	0.046
acvr2a	activin receptor IIa	0.046
robo1	roundabout homolog 1	0.046	Fly
sox19a	SRY-box containing gene 19a	0.046
acvr2b	activin receptor IIb	0.044	Mouse
wtip	Wilms tumor 1 interacting protein	0.042
fzd8a	frizzled homolog 8a	0.042
foxa2	forkhead box A2	0.041	Zebrafish Mouse
sox1a	SRY-box containing gene 1a	0.040
bmper	BMP binding endothelial regulator	0.038
sept7b	septin 7b	0.038
rx3	retinal homeobox gene 3	0.038
atp1a1a.4	ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide	0.036	Fly
cldnh	claudin h	0.036
wif1	wnt inhibitory factor 1	0.035
irf6	interferon regulatory factor 6	0.034
pea3	ETS-domain transcription factor pea3	0.034
tfap2a	transcription factor AP-2 alpha	0.033
ptpra	protein tyrosine phosphatase, receptor type, A	0.033
emx1	empty spiracles homeobox 1	0.033	Fly
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.032
znf503	zinc finger protein 503	0.032	Fly
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.031
tbx1	T-box 1	0.030
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.030
hnf1ba	HNF1 homeobox Ba	0.029
cdh2	cadherin 2, neuronal	0.029
agr2	anterior gradient homolog 2 (Xenopus laevis)	0.029	Mouse
pdgfaa	platelet-derived growth factor alpha a	0.029	Mouse
dlx5a	distal-less homeobox gene 5a	0.029	Mouse
tfeb	transcription factor EB	0.028
arl13b	ADP-ribosylation factor-like 13b	0.027
aldh1a3	aldehyde dehydrogenase 1 family, member A3	0.026
six2a	sine oculis-related homeobox 2a	0.026
ptgs1	prostaglandin-endoperoxide synthase 1	0.026
nkx2.3	NK2 transcription factor related 3	0.025
fsta	follistatin a	0.025
hmx4	H6 family homeobox 4	0.025
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.025
sox21b	SRY-box containing gene 21 b	0.025
raraa	retinoic acid receptor, alpha a	0.025	Mouse
foxa1	forkhead box A1	0.024	Zebrafish Mouse
foxc1a	forkhead box C1a	0.024
ndr2	nodal-related 2	0.024
wnt3	wingless-type MMTV integration site family, member 3	0.023
rarab	retinoic acid receptor, alpha b	0.022	Mouse
flr	fleer	0.021
hhex	hematopoietically expressed homeobox	0.021
ctsl1a	cathepsin L, 1 a	0.021
bmp7b	bone morphogenetic protein 7b	0.021
igfbp3	insulin-like growth factor binding protein 3	0.021
tp63	tumor protein p63	0.020
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.020
her9	hairy-related 9	0.020	Fly
supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.020
slc4a1b	solute carrier family 4, anion exchanger, member 1b	0.019
jag2	jagged 2	0.019
spi1l	spleen focus forming virus (SFFV) proviral integration oncogene spi1 like	0.019
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.019
chd	chordin	0.019
pdlim4	PDZ and LIM domain 4	0.019
dlx2a	distal-less homeobox gene 2a	0.019
gpr126	G protein-coupled receptor 126	0.018
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.018
hoxb5b	homeo box B5b	0.018
vax1	ventral anterior homeobox 1	0.018
ctsba	cathepsin B, a	0.018
wnt11	wingless-type MMTV integration site family, member 11	0.017
chd7	chromodomain helicase DNA binding protein 7	0.017
bmpr2a	bone morphogenetic protein receptor, type II a (serine/threonine kinase)	0.017
sparc	secreted acidic cysteine rich glycoprotein	0.017	Rat Fly
klf2a	Kruppel-like factor 2a	0.017
dag1	dystroglycan 1	0.017	Mouse
efnb1	ephrin B1	0.017
pkd2	polycystic kidney disease 2	0.017
foxj1a	forkhead box J1a	0.017	Human
lrrc6	leucine rich repeat containing 6	0.016
col1a1a	collagen, type I, alpha 1a	0.016
zic2b	zic family member 2 (odd-paired homolog, Drosophila) b	0.016
ncs1a	neuronal calcium sensor 1a	0.016
ctgf	connective tissue growth factor	0.016	Mouse Rat
bon	bonnie and clyde	0.016
six4a	sine oculis homeobox homolog 4a	0.016
zgc:158603	zgc:158603	0.016
foxp1b	forkhead box P1b	0.016	Mouse
btg1	B-cell translocation gene 1	0.016
eomesa	eomesodermin homolog a	0.015
etv2	ets variant gene 2	0.015
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.015	Fly
hoxc1a	homeo box C1a	0.015
shhb	sonic hedgehog b	0.015	Mouse Fly
emx2	empty spiracles homeobox 2	0.015	Fly
six4.3	sine oculis homeobox homolog 4.3	0.015
hoxd11a	homeo box D11a	0.015
dcn	decorin	0.014
npnt	nephronectin	0.014
fev	FEV (ETS oncogene family)	0.014
hmga1a	high mobility group AT-hook 1a	0.014
podxl	podocalyxin-like	0.014
fgfrl1b	fibroblast growth factor receptor-like 1b	0.013
vax2	ventral anterior homeobox 2	0.013
bmp2b	bone morphogenetic protein 2b	0.013	Fly
elk4	ELK4, ETS-domain protein	0.013
phox2a	paired-like homeobox 2a	0.013
lhx5	LIM homeobox 5	0.013
bdnf	brain-derived neurotrophic factor	0.013
hoxa9a	homeo box A9a	0.013
hoxc4a	homeo box C4a	0.013
dacha	dachshund a	0.013
gcm2	glial cells missing homolog 2 (Drosophila)	0.013
cdx4	caudal type homeo box transcription factor 4	0.013
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.013	Fly
cldn5a	claudin 5a	0.013
LOC565459	tight junction protein ZO-1-like	0.013
hs3st1l2	heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like 2	0.013
mbnl2	muscleblind-like 2 (Drosophila)	0.013
pdlim7	PDZ and LIM domain 7	0.012
metrn	meteorin, glial cell differentiation regulator	0.012
tp73	tumor protein p73	0.012
pax6b	paired box gene 6b	0.012
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.012
zic6	zic family member 6	0.012
hand2	heart and neural crest derivatives expressed transcript 2	0.012
ccdc40	coiled-coil domain containing 40	0.012	Mouse
fgf8b	fibroblast growth factor 8 b	0.012	Mouse
sox2	SRY-box containing gene 2	0.012	Mouse
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.012
fxyd1	FXYD domain containing ion transport regulator 1 (phospholemman)	0.012
wnt5b	wingless-type MMTV integration site family, member 5b	0.012	Mouse
sqstm1	sequestosome 1	0.011
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.011
slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.011
tbx2a	T-box gene 2a	0.011
fgf17	fibroblast growth factor 17	0.011
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.011	Fly
amotl2a	angiomotin like 2a	0.011
olfm2	olfactomedin 2	0.011
cct2	chaperonin containing TCP1, subunit 2 (beta)	0.011
id3	inhibitor of DNA binding 3	0.011
skia	nuclear oncoprotein skia	0.011	Mouse
cdh23	cadherin-like 23	0.011	Fly
msxc	muscle segment homeobox C	0.011
csnk1da	casein kinase 1, delta a	0.011
aplnra	apelin receptor a	0.011
rest	RE1-silencing transcription factor	0.011
col2a1a	collagen type II, alpha-1a	0.011
otpb	orthopedia homolog b	0.011
tm9sf2	transmembrane 9 superfamily member 2	0.011
fgf1	fibroblast growth factor 1	0.011	Mouse
mecp2	methyl CpG binding protein 2	0.011
fmnl2b	formin-like 2b	0.011
pcdh8	protocadherin 8	0.011
kal1b	Kallmann syndrome 1b sequence	0.011
edn1	endothelin 1	0.011
nxph1	neurexophilin 1	0.010
si:ch73-60e21.1	si:ch73-60e21.1	0.010
dao.2	D-amino-acid oxidase 2	0.010
hesx1	homeo box (expressed in ES cells) 1	0.010
calb2b	calbindin 2b, (calretinin)	0.010
otpa	orthopedia homolog a	0.010
hoxb3a	homeo box B3a	0.010
zgc:110010	zgc:110010	0.010
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.010
tjp2b	tight junction protein 2b (zona occludens 2)	0.010
caspa	caspase a	0.010
gli1	GLI-Kruppel family member 1	0.010	Mouse Fly