IMP

Process View

Danio rerio

2 genes annotated in zebrafish

hepatic duct development

The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hepatic duct development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "hepatic duct development" (in gray)

Name	Description	Probability	Func Analog Organism
wnt4a	wingless-type MMTV integration site family, member 4a	1.000	Zebrafish
wnt1	wingless-type MMTV integration site family, member 1	0.999	Zebrafish
wnt8b	wingless-type MMTV integration site family, member 8b	0.995	Zebrafish
wnt10a	wingless-type MMTV integration site family, member 10a	0.995	Zebrafish
tbx1	T-box 1	0.974
wnt10b	wingless-type MMTV integration site family, member 10b	0.970	Zebrafish
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.924
wnt3a	wingless-type MMTV integration site family, member 3A	0.922	Zebrafish
wnt2	wingless-type MMTV integration site family member 2	0.900	Zebrafish
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.874	Zebrafish
hnf1ba	HNF1 homeobox Ba	0.847
fgf17	fibroblast growth factor 17	0.799
zfyve26	zinc finger, FYVE domain containing 26	0.784
col11a2	collagen type XI alpha-2	0.776
flh	floating head	0.732
dharma	dharma	0.731
ndr2	nodal-related 2	0.721
dkk1b	dickkopf 1b	0.713
hoxd4a	homeo box D4a	0.690
wnt5b	wingless-type MMTV integration site family, member 5b	0.623	Zebrafish
grem1a	gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)	0.613
gli1	GLI-Kruppel family member 1	0.492
pdlim7	PDZ and LIM domain 7	0.482
wnt3	wingless-type MMTV integration site family, member 3	0.467	Zebrafish
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.421
wnt9b	wingless-type MMTV integration site family, member 9B	0.417	Zebrafish
wnt16	wingless-type MMTV integration site family, member 16	0.412
fgf3	fibroblast growth factor 3	0.406
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.388	Zebrafish
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.360
sfrp1a	secreted frizzled-related protein 1a	0.346
oep	one-eyed pinhead	0.338
her5	hairy-related 5	0.318
lft2	lefty2	0.308
admp	anti-dorsalizing morphogenic protein	0.279
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.262
pth2	parathyroid hormone 2	0.258
map2k7	mitogen-activated protein kinase kinase 7	0.255
lft1	lefty1	0.230
zgc:171802	zgc:171802	0.224
gbx2	gastrulation brain homeo box 2	0.211
frzb	frizzled-related protein	0.199
bmp2a	bone morphogenetic protein 2a	0.198
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.197
scube2	signal peptide, CUB domain, EGF-like 2	0.192
foxj1a	forkhead box J1a	0.169
tcf21	transcription factor 21	0.166
pdlim3b	PDZ and LIM domain 3b	0.160
wnt11	wingless-type MMTV integration site family, member 11	0.149	Zebrafish
zbtb4	zinc finger and BTB domain containing 4	0.143
wnt9a	wingless-type MMTV integration site family, member 9A	0.139	Zebrafish
rest	RE1-silencing transcription factor	0.139
wnt11r	wingless-type MMTV integration site family, member 11, related	0.137	Zebrafish
znf711	zinc finger protein 711	0.135
map2k4b	mitogen-activated protein kinase kinase 4b	0.133
foxb1.2	forkhead box B1.2	0.131
hspb1	heat shock protein, alpha-crystallin-related, 1	0.128
wnt5a	wingless-type MMTV integration site family, member 5a	0.128
nog1	noggin 1	0.128
ntla	no tail a	0.125
sox17	SRY-box containing gene 17	0.121
sfrp5	secreted frizzled-related protein 5	0.120
shhb	sonic hedgehog b	0.118
cdx4	caudal type homeo box transcription factor 4	0.114
map2k4a	mitogen-activated protein kinase kinase 4a	0.114
epb4.1l4	erythrocyte protein band 4.1-like 4	0.114
eng2a	engrailed 2a	0.113
tfpi2	tissue factor pathway inhibitor 2	0.113
ntn1b	netrin 1b	0.112
glra1	glycine receptor, alpha 1	0.110
sfrp1b	secreted frizzled-related protein 1b	0.105
tbx16	T-box gene 16	0.101
eve1	even-skipped-like1	0.100
si:dkey-273o13.1	si:dkey-273o13.1	0.100
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.099
oxtl	oxytocin-like	0.098
LOC566708	FL cytokine receptor-like	0.098
spry2	sprouty homolog 2	0.098
wnt4b	wingless-type MMTV integration site family, member 4b	0.090	Zebrafish
foxa2	forkhead box A2	0.085
frem3	Fras1 related extracellular matrix 3	0.080
twist3	twist3	0.079
hmx4	H6 family homeobox 4	0.079
vent	ventral expressed homeobox	0.079
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.077
cx27.5	connexin 27.5	0.076
pcdh8	protocadherin 8	0.074
fbn2b	fibrillin 2b	0.073
fgf4	fibroblast growth factor 4	0.072
spaw	southpaw	0.071
limk1	LIM domain kinase 1	0.071
wnt8a	wingless-type MMTV integration site family, member 8a	0.070	Zebrafish
buc	bucky ball	0.069
tnnt2a	troponin T2a, cardiac	0.066
col8a1a	collagen, type VIII, alpha 1a	0.065
dbx1a	developing brain homeobox 1a	0.061
igf1ra	insulin-like growth factor 1a receptor	0.057
csnk1da	casein kinase 1, delta a	0.056
epha4a	eph receptor A4a	0.056
bon	bonnie and clyde	0.055
sox32	SRY-box containing gene 32	0.054
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.054
pou5f1	POU domain, class 5, transcription factor 1	0.052
hmx1	H6 homeo box 1	0.051
kop	askopos	0.051
her3	hairy-related 3	0.050
pdlim3a	PDZ and LIM domain 3a	0.049
ndr1	nodal-related 1	0.049
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.046
nog2	noggin 2	0.045
lhx1b	LIM homeobox 1b	0.045
comta	catechol-O-methyltransferase a	0.045
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.044
sp5l	Sp5 transcription factor-like	0.044
bmp4	bone morphogenetic protein 4	0.043
mapk14a	mitogen-activated protein kinase 14a	0.042
ihha	Indian hedgehog homolog a	0.042
sb:cb81	sb:cb81	0.041
znf503	zinc finger protein 503	0.040
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.040
esrra	estrogen-related receptor alpha	0.039
dab1b	disabled homolog 1b (Drosophila)	0.039
satb2	SATB homeobox 2	0.038
chd	chordin	0.038
bmp7a	bone morphogenetic protein 7a	0.038
ephb4b	eph receptor B4b	0.037
bhlhe41	basic helix-loop-helix family, member e41	0.035
cryaa	crystallin, alpha A	0.034
ism1	isthmin 1	0.034
ved	ventrally expressed dharma/bozozok antagonist	0.034
her1	hairy-related 1	0.034
fzd10	frizzled homolog 10	0.034
snai1b	snail homolog 1b (Drosophila)	0.034
sp2	sp2 transcription factor	0.033
chrna4	cholinergic receptor, nicotinic, alpha 4	0.033
LOC569376	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2-like	0.032
ptch2	patched 2	0.032
stac3	SH3 and cysteine rich domain 3	0.031
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.030
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.030
gli2b	GLI-Kruppel family member GLI2b	0.029
stat1b	signal transducer and activator of transcription 1b	0.029
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.029	Zebrafish
sass6	spindle assembly 6 homolog (C. elegans)	0.029
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.028
aplnra	apelin receptor a	0.028
tp73	tumor protein p73	0.028
amotl2a	angiomotin like 2a	0.027
lrmp	lymphoid-restricted membrane protein	0.027
si:ch1073-351m12.1	si:ch1073-351m12.1	0.027
twist1a	twist1a	0.026
oprm1	opioid receptor, mu 1	0.026
fn1	fibronectin 1	0.025
gro2	groucho 2	0.024
tll1	tolloid-like 1	0.024
LOC100000687	signal peptide, CUB and EGF-like domain-containing protein 3-like	0.024
ids	iduronate 2-sulfatase	0.024
veph	ventricular zone expressed PH domain protein	0.024
glcea	glucuronyl C5-epimerase a	0.023
fzd8b	frizzled homolog 8b	0.022
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.022
gyltl1b	glycosyltransferase-like 1b	0.021
lef1	lymphocyte enhancer binding factor 1	0.021
npy4r	neuropeptide Y receptor Y4	0.021
oprd1a	opioid receptor, delta 1a	0.021
pglyrp2	peptidoglycan recognition protein 2	0.020
ca15b	carbonic anhydrase XV b	0.020
has3	hyaluronan synthase 3	0.020
mapk8b	mitogen-activated protein kinase 8b	0.020
glceb	glucuronyl C5-epimerase b	0.020
atp1a2a	ATPase, Na+/K+ transporting, alpha 2a polypeptide	0.020
cdkl1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.019
klf4a	Kruppel-like transcription factor 4a	0.019
gbx1	gastrulation brain homeobox 1	0.019
cfl2l	cofilin 2, like	0.019
sox11b	SRY-box containing gene 11b	0.019
rnd1l	Rho family GTPase 1 like	0.019
mapk4	mitogen-activated protein kinase 4	0.018
vax1	ventral anterior homeobox 1	0.018
smad9	MAD homolog 9 (Drosophila)	0.018
pcdh18b	protocadherin 18b	0.018
grem2	gremlin 2, cysteine knot superfamily	0.018
myod1	myogenic differentiation 1	0.018
LOC100537862	hypothetical protein LOC100537862	0.018
fgfr1b	fibroblast growth factor receptor 1b	0.017
sox4b	SRY-box containing gene 4b	0.017
dag1	dystroglycan 1	0.017
gata4	GATA-binding protein 4	0.017
htra1a	HtrA serine peptidase 1a	0.017
e2f5	E2F transcription factor 5	0.017
mga	MAX gene associated	0.016
fgf6a	fibroblast growth factor 6a	0.016
limk2	LIM domain kinase 2	0.016
grin1a	glutamate receptor, ionotropic, N-methyl D-aspartate 1a	0.016
sox2	SRY-box containing gene 2	0.016
bactin2	bactin2	0.015
og9x	OG9 homeobox gene	0.015
ier2	immediate early response 2	0.015
wif1	wnt inhibitory factor 1	0.015
runx2b	runt-related transcription factor 2b	0.015
notum3	notum 3	0.015
foxd5	forkhead box D5	0.014
ptch1	patched 1	0.014
dld	deltaD	0.014
wu:fj62d01	wu:fj62d01	0.014
vax2	ventral anterior homeobox 2	0.014
si:dkey-105e17.1	si:dkey-105e17.1	0.014
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.014
lzts2a	leucine zipper, putative tumor suppressor 2a	0.014
gpc4	glypican 4	0.013
nkx2.5	NK2 transcription factor related 5	0.013
tob1a	transducer of ERBB2, 1a	0.013
LOC100329473	girdin-like	0.013
zgc:171495	zgc:171495	0.013
vox	ventral homeobox	0.013
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.013
myf6	myogenic factor 6	0.013
tbx24	T-box 24	0.012
nkd1	naked cuticle homolog 1 (Drosophila)	0.012
eif3hb	eukaryotic translation initiation factor 3, subunit H, b	0.012
syt5a	synaptotagmin Va	0.012
si:ch211-202h22.9	si:ch211-202h22.9	0.012
brd4	bromodomain containing 4	0.012
foxp1b	forkhead box P1b	0.012
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.012
trim3a	tripartite motif-containing 3a	0.012
gngt2b	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b	0.012
nkx1.2la	NK1 transcription factor related 2-like,a	0.012
araf	v-raf murine sarcoma 3611 viral oncogene homolog	0.012
mxtx2	mix-type homeobox gene 2	0.012
bmp1a	bone morphogenetic protein 1a	0.012
si:dkey-236e20.2	si:dkey-236e20.2	0.012
chrm2a	cholinergic receptor, muscarinic 2a	0.012
zfpm1	zinc finger protein, multitype 1	0.012
cyp11b2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.012
mbnl1	muscleblind-like (Drosophila)	0.012
or115-10	odorant receptor, family F, subfamily 115, member 10	0.012
cables1	Cdk5 and Abl enzyme substrate 1	0.012
gpr173	G-protein coupled receptor 173	0.011
cpa2	carboxypeptidase A2 (pancreatic)	0.011
msxb	muscle segment homeobox B	0.011
smo	smoothened homolog (Drosophila)	0.011
emx1	empty spiracles homeobox 1	0.011
pdlim2	PDZ and LIM domain 2 (mystique)	0.011
pdlim5	PDZ and LIM domain 5	0.011
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.011
twist1b	twist1b	0.011
myf5	myogenic factor 5	0.011
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.011
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.011
otx1b	orthodenticle homolog 1b	0.011
rxrbb	retinoid x receptor, beta b	0.011
gle1	GLE1 RNA export mediator homolog (yeast)	0.011
angpt1	angiopoietin 1	0.011
olig3	oligodendrocyte transcription factor 3	0.011
otul	OTU like protein	0.011
nkd2	naked cuticle homolog 2 and naked 2a	0.011
pax8	paired box gene 8	0.011
sult1st4	sulfotransferase family 1, cytosolic sulfotransferase 4	0.011
ntn2	netrin 2	0.010
oprk1	opioid receptor, kappa 1	0.010
hoxa13b	homeo box A13b	0.010