The network for 'regulation of myeloid leukocyte mediated immunity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of myeloid leukocyte mediated immunity

Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.

Homo sapiens
Name Description Probability Func Analog Organism
SYK spleen tyrosine kinase 1.000
CXCL3 chemokine (C-X-C motif) ligand 3 0.989
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.988
CXCL2 chemokine (C-X-C motif) ligand 2 0.975
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.960
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.952
UBASH3B ubiquitin associated and SH3 domain containing B 0.947
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.933
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.924
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.912
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.910
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.894
LCK lymphocyte-specific protein tyrosine kinase 0.892
IL4R interleukin 4 receptor 0.889
IL8 interleukin 8 0.887
BLNK B-cell linker 0.624
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.579
TFF1 trefoil factor 1 0.521
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.412
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.411
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.402
EGFR epidermal growth factor receptor 0.399
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.398
C19orf50 chromosome 19 open reading frame 50 0.363
CRH corticotropin releasing hormone 0.349
VAV1 vav 1 guanine nucleotide exchange factor 0.312
IL1B interleukin 1, beta 0.310
BTK Bruton agammaglobulinemia tyrosine kinase 0.284
AIF1 allograft inflammatory factor 1 0.283
CFH complement factor H 0.279
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.263
IL2RG interleukin 2 receptor, gamma 0.250
CCL20 chemokine (C-C motif) ligand 20 0.238
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.217
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.216
IL6 interleukin 6 (interferon, beta 2) 0.214
IL4 interleukin 4 0.205
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.203
GRB2 growth factor receptor-bound protein 2 0.173
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.168
EPOR erythropoietin receptor 0.156
TYROBP TYRO protein tyrosine kinase binding protein 0.150
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.150
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.146
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.141
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.137
ZNF775 zinc finger protein 775 0.134
BAI1 brain-specific angiogenesis inhibitor 1 0.131
SPRR2A small proline-rich protein 2A 0.124
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.113
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.112
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.106
CXCL5 chemokine (C-X-C motif) ligand 5 0.096
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.096
CFI complement factor I 0.095
GAB1 GRB2-associated binding protein 1 0.083
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.083
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.082
PDZK1 PDZ domain containing 1 0.081
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.081
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.080
HCK hemopoietic cell kinase 0.079
SBF1 SET binding factor 1 0.077
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.075
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.073
CD33 CD33 molecule 0.067
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.065
PLCG1 phospholipase C, gamma 1 0.065
DOK3 docking protein 3 0.064
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.064
SIRPB1 signal-regulatory protein beta 1 0.062
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.061
ITK IL2-inducible T-cell kinase 0.059
PTPRA protein tyrosine phosphatase, receptor type, A 0.057
GRAP2 GRB2-related adaptor protein 2 0.055
IGSF6 immunoglobulin superfamily, member 6 0.054
CLEC7A C-type lectin domain family 7, member A 0.054
ALOX5 arachidonate 5-lipoxygenase 0.052
CFB complement factor B 0.052
HK3 hexokinase 3 (white cell) 0.051
CCR1 chemokine (C-C motif) receptor 1 0.051
INADL InaD-like (Drosophila) 0.051
SOS1 son of sevenless homolog 1 (Drosophila) 0.050
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 0.048
ZC3HC1 zinc finger, C3HC-type containing 1 0.047
CLEC4E C-type lectin domain family 4, member E 0.046
IFT20 intraflagellar transport 20 homolog (Chlamydomonas) 0.045
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.044
STK4 serine/threonine kinase 4 0.044
CCL2 chemokine (C-C motif) ligand 2 0.043
VSIG4 V-set and immunoglobulin domain containing 4 0.043
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.042
FASLG Fas ligand (TNF superfamily, member 6) 0.042
CD300C CD300c molecule 0.041
CCL7 chemokine (C-C motif) ligand 7 0.040
C5AR1 complement component 5a receptor 1 0.039
RGS12 regulator of G-protein signaling 12 0.039
SLA Src-like-adaptor 0.039
NSF N-ethylmaleimide-sensitive factor 0.038
KRT81 keratin 81 0.037
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ifng interferon gamma 0.967
Cd247 CD247 antigen 0.789
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.766
Inpp5d inositol polyphosphate-5-phosphatase D 0.712
Mefv Mediterranean fever 0.509
Cd22 CD22 antigen 0.443
Ptprc protein tyrosine phosphatase, receptor type, C 0.441
Ikzf1 IKAROS family zinc finger 1 0.404
Igh immunoglobulin heavy chain complex 0.363
Ccl2 chemokine (C-C motif) ligand 2 0.362
Tyrobp TYRO protein tyrosine kinase binding protein 0.319
Grb2 growth factor receptor bound protein 2 0.248
Cd40 CD40 antigen 0.242
Selp selectin, platelet 0.217
C3ar1 complement component 3a receptor 1 0.209
Il4ra interleukin 4 receptor, alpha 0.205
Grap2 GRB2-related adaptor protein 2 0.204
Cxcr2 chemokine (C-X-C motif) receptor 2 0.201
Fcrla Fc receptor-like A 0.198
Lyz2 lysozyme 2 0.195
Tlr2 toll-like receptor 2 0.194
Ccl3 chemokine (C-C motif) ligand 3 0.190
Il1rn interleukin 1 receptor antagonist 0.189
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.183
C1qb complement component 1, q subcomponent, beta polypeptide 0.182
Tnf tumor necrosis factor 0.179
Cd4 CD4 antigen 0.174
Sfpi1 SFFV proviral integration 1 0.154
Il1b interleukin 1 beta 0.153
Hcst hematopoietic cell signal transducer 0.146
Clec4d C-type lectin domain family 4, member d 0.145
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.136
Ccr1 chemokine (C-C motif) receptor 1 0.129
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.122
Clec4n C-type lectin domain family 4, member n 0.113
Il18rap interleukin 18 receptor accessory protein 0.112
Ccr6 chemokine (C-C motif) receptor 6 0.106
Met met proto-oncogene 0.105
Cxcl2 chemokine (C-X-C motif) ligand 2 0.103
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.097
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.093
Fasl Fas ligand (TNF superfamily, member 6) 0.088
Il2rg interleukin 2 receptor, gamma chain 0.082
Icos inducible T-cell co-stimulator 0.081
Nfam1 Nfat activating molecule with ITAM motif 1 0.081
Prdm1 PR domain containing 1, with ZNF domain 0.081
Ptpre protein tyrosine phosphatase, receptor type, E 0.077
Ciita class II transactivator 0.076
Trem3 triggering receptor expressed on myeloid cells 3 0.076
Irg1 immunoresponsive gene 1 0.074
Xcr1 chemokine (C motif) receptor 1 0.073
Fcgr1 Fc receptor, IgG, high affinity I 0.070
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.069
Ccl4 chemokine (C-C motif) ligand 4 0.068
Fcgr3 Fc receptor, IgG, low affinity III 0.068
Il2 interleukin 2 0.067
Slpi secretory leukocyte peptidase inhibitor 0.065
Cd180 CD180 antigen 0.064
Pik3cg phosphoinositide-3-kinase, catalytic, gamma polypeptide 0.064
C3 complement component 3 0.063
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 0.063
Cd86 CD86 antigen 0.062
Il10ra interleukin 10 receptor, alpha 0.061
Lck lymphocyte protein tyrosine kinase 0.061
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.059
Ubd ubiquitin D 0.058
Hk3 hexokinase 3 0.058
Il4 interleukin 4 0.058
Blk B lymphoid kinase 0.056
Ptk2 PTK2 protein tyrosine kinase 2 0.056
Fas Fas (TNF receptor superfamily member 6) 0.055
C5ar1 complement component 5a receptor 1 0.054
Itgam integrin alpha M 0.053
Snai1 snail homolog 1 (Drosophila) 0.052
Cbl Casitas B-lineage lymphoma 0.051
Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) 0.051
Niacr1 niacin receptor 1 0.050
Il1f9 interleukin 1 family, member 9 0.049
Bdkrb1 bradykinin receptor, beta 1 0.049
Ccl17 chemokine (C-C motif) ligand 17 0.048
Pilrb1 paired immunoglobin-like type 2 receptor beta 1 0.047
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.047
Apoe apolipoprotein E 0.046
Csf1r colony stimulating factor 1 receptor 0.046
Msr1 macrophage scavenger receptor 1 0.045
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.045
Fpr2 formyl peptide receptor 2 0.044
Ncf4 neutrophil cytosolic factor 4 0.044
Ager advanced glycosylation end product-specific receptor 0.044
Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.044
Ncr1 natural cytotoxicity triggering receptor 1 0.044
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.043
Prkce protein kinase C, epsilon 0.043
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.042
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.042
Batf basic leucine zipper transcription factor, ATF-like 0.042
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.041
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.041
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.041
Cr2 complement receptor 2 0.040
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism