The network for 'somitogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

somitogenesis

The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.

Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Pax3 paired box gene 3 1.000
Pitx2 paired-like homeodomain transcription factor 2 1.000
Foxc1 forkhead box C1 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 1.000
Nodal nodal 1.000
Tbx1 T-box 1 1.000
Fgf8 fibroblast growth factor 8 1.000
Msx1 homeobox, msh-like 1 1.000
Rarg retinoic acid receptor, gamma 1.000
Fgfr1 fibroblast growth factor receptor 1 0.999
Psen1 presenilin 1 0.999
Eya1 eyes absent 1 homolog (Drosophila) 0.999
Foxg1 forkhead box G1 0.999
Prrx1 paired related homeobox 1 0.999
Hand2 heart and neural crest derivatives expressed transcript 2 0.999
Bmp4 bone morphogenetic protein 4 0.998
Foxc2 forkhead box C2 0.998
Ctnnb1 catenin (cadherin associated protein), beta 1 0.998
Tbx3 T-box 3 0.997
Fgfr2 fibroblast growth factor receptor 2 0.997
Tcfap2a transcription factor AP-2, alpha 0.996
Dlx5 distal-less homeobox 5 0.995
Nog noggin 0.991
Fgf10 fibroblast growth factor 10 0.991
Wnt3a wingless-related MMTV integration site 3A 0.989
Lef1 lymphoid enhancer binding factor 1 0.988
Lhx1 LIM homeobox protein 1 0.988
Emx1 empty spiracles homolog 1 (Drosophila) 0.987
Pax2 paired box gene 2 0.984
Hoxa1 homeobox A1 0.984
Tgfb2 transforming growth factor, beta 2 0.984
Pax6 paired box gene 6 0.984
Chrd chordin 0.983
Lmx1a LIM homeobox transcription factor 1 alpha 0.982
Gsc goosecoid homeobox 0.978
Hoxa3 homeobox A3 0.977
Notch1 Notch gene homolog 1 (Drosophila) 0.977
Vegfa vascular endothelial growth factor A 0.974
Hes1 hairy and enhancer of split 1 (Drosophila) 0.974
Bdnf brain derived neurotrophic factor 0.971
Bmp7 bone morphogenetic protein 7 0.971
Lmx1b LIM homeobox transcription factor 1 beta 0.970
Prrx2 paired related homeobox 2 0.967
Smo smoothened homolog (Drosophila) 0.966
Lrp6 low density lipoprotein receptor-related protein 6 0.965
Chd7 chromodomain helicase DNA binding protein 7 0.965
Rb1 retinoblastoma 1 0.962
Zic3 zinc finger protein of the cerebellum 3 0.962
Ednra endothelin receptor type A 0.960
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.959
Sox2 SRY-box containing gene 2 0.958
Msx2 homeobox, msh-like 2 0.957
Hoxa2 homeobox A2 0.957
Emx2 empty spiracles homolog 2 (Drosophila) 0.950
Meox2 mesenchyme homeobox 2 0.949
Hand1 heart and neural crest derivatives expressed transcript 1 0.934
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.929
Gata4 GATA binding protein 4 0.929
Vangl2 vang-like 2 (van gogh, Drosophila) 0.929
Snai1 snail homolog 1 (Drosophila) 0.926
Pax8 paired box gene 8 0.919
Foxh1 forkhead box H1 0.917
Otx1 orthodenticle homolog 1 (Drosophila) 0.917
Hoxa13 homeobox A13 0.917
Gli2 GLI-Kruppel family member GLI2 0.914
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.913
Rarb retinoic acid receptor, beta 0.907
Acvr1 activin A receptor, type 1 0.897
En1 engrailed 1 0.887
Hoxd13 homeobox D13 0.879
Gbx2 gastrulation brain homeobox 2 0.877
Smad3 MAD homolog 3 (Drosophila) 0.866
Pbx1 pre B-cell leukemia transcription factor 1 0.857
Mecom MDS1 and EVI1 complex locus 0.855
Wnt6 wingless-related MMTV integration site 6 0.853
Apc adenomatosis polyposis coli 0.853
Wt1 Wilms tumor 1 homolog 0.851
Gdnf glial cell line derived neurotrophic factor 0.846
Neurod1 neurogenic differentiation 1 0.843
Gata6 GATA binding protein 6 0.836
Twist2 twist homolog 2 (Drosophila) 0.834
Dlx2 distal-less homeobox 2 0.827
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.816
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.810
Tbx2 T-box 2 0.809
Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.805
Mesp1 mesoderm posterior 1 0.804
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.801
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.782
Sox9 SRY-box containing gene 9 0.779
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.778
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.776
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.773
Sox11 SRY-box containing gene 11 0.771
Pax9 paired box gene 9 0.769
Pitx1 paired-like homeodomain transcription factor 1 0.741
Fgf15 fibroblast growth factor 15 0.739
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
dld deltaD 0.999
dlc deltaC 0.999
myod1 myogenic differentiation 1 0.998
myf5 myogenic factor 5 0.997
gli1 GLI-Kruppel family member 1 0.996
fn1 fibronectin 1 0.996
cdh2 cadherin 2, neuronal 0.994
tbx16 T-box gene 16 0.993
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.987
wnt11 wingless-type MMTV integration site family, member 11 0.979
pcdh10b protocadherin 10b 0.979
lef1 lymphocyte enhancer binding factor 1 0.976
jag2 jagged 2 0.976
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.962
bmp4 bone morphogenetic protein 4 0.961
mespa mesoderm posterior a 0.952
wnt5b wingless-type MMTV integration site family, member 5b 0.947
wnt1 wingless-type MMTV integration site family, member 1 0.945
hhip hedgehog interacting protein 0.944
hnf1ba HNF1 homeobox Ba 0.930
her7 hairy and enhancer of split related-7 0.926
her1 hairy-related 1 0.922
dla deltaA 0.922
wnt3a wingless-type MMTV integration site family, member 3A 0.919
otx2 orthodenticle homolog 2 0.911
neo1 neogenin 1 0.903
pax7a paired box gene 7a 0.898
ntla no tail a 0.897
wnt4a wingless-type MMTV integration site family, member 4a 0.891
fgf17 fibroblast growth factor 17 0.888
foxd5 forkhead box D5 0.886
oep one-eyed pinhead 0.879
tbx24 T-box 24 0.871
fezf2 FEZ family zinc finger 2 0.862
bmp2b bone morphogenetic protein 2b 0.860
fgf8a fibroblast growth factor 8 a 0.855
has2 hyaluronan synthase 2 0.855
desma desmin a 0.849
lamb1a laminin, beta 1a 0.799
pax2a paired box gene 2a 0.785
hes6 hairy and enhancer of split 6 (Drosophila) 0.784
tp53 tumor protein p53 0.778
eomesa eomesodermin homolog a 0.760
gli2a GLI-Kruppel family member GLI2a 0.756
sema3aa semaphorin 3aa 0.752
tbx1 T-box 1 0.743
pdlim3b PDZ and LIM domain 3b 0.735
foxg1a forkhead box G1a 0.734
smyhc2 slow myosin heavy chain 2 0.732
myog myogenin 0.728
fgfr2 fibroblast growth factor receptor 2 0.725
smyhc1 slow myosin heavy chain 1 0.724
her15.1 hairy and enhancer of split-related 15.1 0.719
actc1b actin, alpha, cardiac muscle 1b 0.714
fgf3 fibroblast growth factor 3 0.714
ptch1 patched 1 0.693
mespb mesoderm posterior b 0.669
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.667
pdlim3a PDZ and LIM domain 3a 0.662
igf1 insulin-like growth factor 1 0.661
cdx4 caudal type homeo box transcription factor 4 0.658
ttnb titin b 0.654
ttna titin a 0.649
msgn1 mesogenin 1 0.647
ndr2 nodal-related 2 0.637
ptch2 patched 2 0.635
sox9a SRY-box containing gene 9a 0.631
esrra estrogen-related receptor alpha 0.624
notch2 notch homolog 2 0.621
supt6h suppressor of Ty 6 homolog 0.614
crip2 cysteine-rich protein 2 0.612
meis1 myeloid ecotropic viral integration 1 0.610
shha sonic hedgehog a 0.608
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.604
notch3 notch homolog 3 0.603
pax3a paired box gene 3a 0.603
axin2 axin 2 (conductin, axil) 0.594
eng2a engrailed 2a 0.591
dbx1a developing brain homeobox 1a 0.581
kdrl kinase insert domain receptor like 0.577
sox17 SRY-box containing gene 17 0.576
ripply1 ripply1 0.569
cxcr4a chemokine (C-X-C motif) receptor 4a 0.558
par1 paraxis 0.556
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.551
ripply2 ripply2 0.549
prkci protein kinase C, iota 0.538
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.525
neurog1 neurogenin 1 0.516
cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b 0.516
spry4 sprouty (Drosophila) homolog 4 0.516
dmrt2a doublesex and mab-3 related transcription factor 2a 0.513
rx3 retinal homeobox gene 3 0.509
epha4b eph receptor A4b 0.504
emx3 empty spiracles homeobox 3 0.498
pcdh8 protocadherin 8 0.493
boc brother of CDO 0.487
snai1b snail homolog 1b (Drosophila) 0.485
lama5 laminin, alpha 5 0.485
tll1 tolloid-like 1 0.484
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.995
FN1 fibronectin 1 0.973
SMAD2 SMAD family member 2 0.972
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.968
LRP6 low density lipoprotein receptor-related protein 6 0.946
PSEN1 presenilin 1 0.942
MEOX2 mesenchyme homeobox 2 0.933
PAX3 paired box 3 0.924
FLNA filamin A, alpha 0.922
BBS2 Bardet-Biedl syndrome 2 0.871
FLNB filamin B, beta 0.860
ATXN1 ataxin 1 0.839
PGK1 phosphoglycerate kinase 1 0.826
BMP2 bone morphogenetic protein 2 0.825
TRRAP transformation/transcription domain-associated protein 0.816
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.803
ERBB2IP erbb2 interacting protein 0.794
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.772
JAG1 jagged 1 0.767
SMAD7 SMAD family member 7 0.763
PGAM1 phosphoglycerate mutase 1 (brain) 0.749
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.744
PAX1 paired box 1 0.700
GSK3B glycogen synthase kinase 3 beta 0.672
SRPK2 SRSF protein kinase 2 0.655
MEOX1 mesenchyme homeobox 1 0.611
HIPK2 homeodomain interacting protein kinase 2 0.572
MAPK8 mitogen-activated protein kinase 8 0.552
APC adenomatous polyposis coli 0.539
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.487
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.473
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.459
SOX10 SRY (sex determining region Y)-box 10 0.440
CREBBP CREB binding protein 0.423
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.412
ZFX zinc finger protein, X-linked 0.408
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.375
ITGB1BP3 integrin beta 1 binding protein 3 0.370
PKM2 pyruvate kinase, muscle 0.367
SMAD4 SMAD family member 4 0.355
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.352
ACTG1 actin, gamma 1 0.349
ENG endoglin 0.349
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.336
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.334
ATXN7 ataxin 7 0.325
POU3F2 POU class 3 homeobox 2 0.317
TCF4 transcription factor 4 0.316
CYR61 cysteine-rich, angiogenic inducer, 61 0.315
MED24 mediator complex subunit 24 0.299
TBK1 TANK-binding kinase 1 0.294
FZD1 frizzled homolog 1 (Drosophila) 0.292
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.288
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.282
QKI quaking homolog, KH domain RNA binding (mouse) 0.280
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.278
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.274
MAML1 mastermind-like 1 (Drosophila) 0.269
NBN nibrin 0.268
USP9X ubiquitin specific peptidase 9, X-linked 0.261
BZW1 basic leucine zipper and W2 domains 1 0.256
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.246
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 0.245
PCM1 pericentriolar material 1 0.224
LDHA lactate dehydrogenase A 0.223
CAV2 caveolin 2 0.222
MED12 mediator complex subunit 12 0.222
CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.220
CFL1 cofilin 1 (non-muscle) 0.216
SRI sorcin 0.211
SKI v-ski sarcoma viral oncogene homolog (avian) 0.208
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.206
ESR1 estrogen receptor 1 0.205
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.203
SMAD3 SMAD family member 3 0.203
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.201
ACTB actin, beta 0.195
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.195
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.193
SPEN spen homolog, transcriptional regulator (Drosophila) 0.190
DKK1 dickkopf homolog 1 (Xenopus laevis) 0.188
IGF2R insulin-like growth factor 2 receptor 0.186
CTGF connective tissue growth factor 0.185
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.181
MBNL1 muscleblind-like (Drosophila) 0.179
BMP1 bone morphogenetic protein 1 0.177
XIAP X-linked inhibitor of apoptosis 0.177
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.176
EIF4E eukaryotic translation initiation factor 4E 0.172
EP300 E1A binding protein p300 0.170
BTRC beta-transducin repeat containing 0.166
SIRT1 sirtuin 1 0.162
MYH9 myosin, heavy chain 9, non-muscle 0.161
SPDEF SAM pointed domain containing ets transcription factor 0.157
EXOC7 exocyst complex component 7 0.153
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.149
ZFYVE9 zinc finger, FYVE domain containing 9 0.149
GLIS2 GLIS family zinc finger 2 0.146
MED15 mediator complex subunit 15 0.146
TTN titin 0.146
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism