The network for 'sterol esterification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

sterol esterification

A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and a sterol molecule (e.g. cholesterol).

Name Description Probability Func Analog Organism
Apoe apolipoprotein E 0.999
Ldlr low density lipoprotein receptor 0.957
Lepr leptin receptor 0.938
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.924
Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 0.806
Ren1 renin 1 structural 0.728
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.582
Apoa1 apolipoprotein A-I 0.520
Agtr1a angiotensin II receptor, type 1a 0.513
Nos3 nitric oxide synthase 3, endothelial cell 0.453
Agtrap angiotensin II, type I receptor-associated protein 0.401
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.289
Efemp2 epidermal growth factor-containing fibulin-like extracellular matrix protein 2 0.267
Npc1 Niemann Pick type C1 0.173
Scd1 stearoyl-Coenzyme A desaturase 1 0.151
Lyz2 lysozyme 2 0.150
Lrp1 low density lipoprotein receptor-related protein 1 0.140
Pparg peroxisome proliferator activated receptor gamma 0.135
Tgfb1 transforming growth factor, beta 1 0.109
Eln elastin 0.103
Ptgs2 prostaglandin-endoperoxide synthase 2 0.092
Apom apolipoprotein M 0.082
Prnp prion protein 0.078
Klf15 Kruppel-like factor 15 0.074
Aldob aldolase B, fructose-bisphosphate 0.071
Vegfa vascular endothelial growth factor A 0.062
Vdr vitamin D receptor 0.058
Nos1 nitric oxide synthase 1, neuronal 0.057
Abhd5 abhydrolase domain containing 5 0.052
Apob apolipoprotein B 0.052
F12 coagulation factor XII (Hageman factor) 0.048
Gcgr glucagon receptor 0.048
Vav2 vav 2 oncogene 0.048
C3 complement component 3 0.047
Lpin1 lipin 1 0.046
Pltp phospholipid transfer protein 0.046
Apoc4 apolipoprotein C-IV 0.044
Rxra retinoid X receptor alpha 0.042
Ahsg alpha-2-HS-glycoprotein 0.038
Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 0.038
Nr1h3 nuclear receptor subfamily 1, group H, member 3 0.037
Mt1 metallothionein 1 0.037
Scarb1 scavenger receptor class B, member 1 0.035
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.035
Fga fibrinogen alpha chain 0.034
Lcat lecithin cholesterol acyltransferase 0.034
Atp7a ATPase, Cu++ transporting, alpha polypeptide 0.031
Apoc3 apolipoprotein C-III 0.031
Apoa2 apolipoprotein A-II 0.031
Tgfbr2 transforming growth factor, beta receptor II 0.029
Ambp alpha 1 microglobulin/bikunin 0.028
Hr hairless 0.028
Nr3c2 nuclear receptor subfamily 3, group C, member 2 0.028
Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 0.028
Myo7a myosin VIIA 0.027
Mt2 metallothionein 2 0.027
Apoa4 apolipoprotein A-IV 0.026
Pnpla2 patatin-like phospholipase domain containing 2 0.026
Apoc1 apolipoprotein C-I 0.026
Fbn1 fibrillin 1 0.025
F2 coagulation factor II 0.025
Plg plasminogen 0.023
Soat1 sterol O-acyltransferase 1 0.022
Alb albumin 0.021
Agtr2 angiotensin II receptor, type 2 0.020
Fgg fibrinogen gamma chain 0.020
Timp3 tissue inhibitor of metalloproteinase 3 0.020
Gc group specific component 0.020
Ghr growth hormone receptor 0.019
Myo6 myosin VI 0.019
Mertk c-mer proto-oncogene tyrosine kinase 0.019
Fasn fatty acid synthase 0.018
Ttr transthyretin 0.018
Lpl lipoprotein lipase 0.018
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.017
Umod uromodulin 0.016
Fgb fibrinogen beta chain 0.016
Idua iduronidase, alpha-L- 0.016
Sqle squalene epoxidase 0.016
Sdsl serine dehydratase-like 0.015
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.015
Ppara peroxisome proliferator activated receptor alpha 0.015
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.015
Angptl4 angiopoietin-like 4 0.014
Angptl3 angiopoietin-like 3 0.014
Serpinf2 serine (or cysteine) peptidase inhibitor, clade F, member 2 0.014
Pcx pyruvate carboxylase 0.014
Dsg4 desmoglein 4 0.013
Sstr3 somatostatin receptor 3 0.013
Sec14l2 SEC14-like 2 (S. cerevisiae) 0.013
Slc38a3 solute carrier family 38, member 3 0.012
Hpn hepsin 0.012
Lmf1 lipase maturation factor 1 0.012
Mus81 MUS81 endonuclease homolog (yeast) 0.012
Slc12a1 solute carrier family 12, member 1 0.012
Spp1 secreted phosphoprotein 1 0.012
Wnk4 WNK lysine deficient protein kinase 4 0.011
Mpv17 MpV17 mitochondrial inner membrane protein 0.011
Itih3 inter-alpha trypsin inhibitor, heavy chain 3 0.011
Dhcr7 7-dehydrocholesterol reductase 0.011
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
APOA1 apolipoprotein A-I 1.000
HP haptoglobin 0.998
ALB albumin 0.997
APOC1 apolipoprotein C-I 0.983
A2M alpha-2-macroglobulin 0.948
LCAT lecithin-cholesterol acyltransferase 0.926
APOC3 apolipoprotein C-III 0.838
RRAGC Ras-related GTP binding C 0.480
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 0.467
FGA fibrinogen alpha chain 0.439
RLN3 relaxin 3 0.401
APOC2 apolipoprotein C-II 0.356
DHCR7 7-dehydrocholesterol reductase 0.344
TIMP3 TIMP metallopeptidase inhibitor 3 0.248
TTR transthyretin 0.203
APOA2 apolipoprotein A-II 0.160
APOE apolipoprotein E 0.156
C7orf59 chromosome 7 open reading frame 59 0.142
RRAGA Ras-related GTP binding A 0.141
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 0.109
TXNDC2 thioredoxin domain containing 2 (spermatozoa) 0.081
SSR1 signal sequence receptor, alpha 0.070
ARRB1 arrestin, beta 1 0.044
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) 0.041
APOB apolipoprotein B (including Ag(x) antigen) 0.036
PLTP phospholipid transfer protein 0.034
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.023
FAM83C family with sequence similarity 83, member C 0.022
DNTT deoxynucleotidyltransferase, terminal 0.017
TF transferrin 0.016
AHSG alpha-2-HS-glycoprotein 0.015
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.015
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.015
FADS1 fatty acid desaturase 1 0.014
CP ceruloplasmin (ferroxidase) 0.014
LBP lipopolysaccharide binding protein 0.014
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.012
CLEC4G C-type lectin domain family 4, member G 0.011
HPX hemopexin 0.011
SCARB1 scavenger receptor class B, member 1 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism