IMP
Process View
The network for 'protein autoprocessing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
protein autoprocessing
Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Casp1 | caspase 1 | 0.880 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.719 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.700 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.468 | |
| Gbp5 | guanylate binding protein 5 | 0.254 | |
| Tlr4 | toll-like receptor 4 | 0.252 | |
| Il18 | interleukin 18 | 0.233 | |
| Col2a1 | collagen, type II, alpha 1 | 0.191 | |
| Pycard | PYD and CARD domain containing | 0.190 | |
| Col1a1 | collagen, type I, alpha 1 | 0.173 | |
| Ctsb | cathepsin B | 0.132 | |
| Aim2 | absent in melanoma 2 | 0.108 | |
| Zbtb16 | zinc finger and BTB domain containing 16 | 0.101 | |
| Sat1 | spermidine/spermine N1-acetyl transferase 1 | 0.090 | |
| Il1b | interleukin 1 beta | 0.083 | |
| Cd14 | CD14 antigen | 0.074 | |
| Ar | androgen receptor | 0.068 | |
| Ppl | periplakin | 0.066 | |
| Foxf1a | forkhead box F1a | 0.064 | |
| Elf3 | E74-like factor 3 | 0.055 | |
| Rab25 | RAB25, member RAS oncogene family | 0.055 | |
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.055 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.053 | |
| Mpeg1 | macrophage expressed gene 1 | 0.052 | |
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.051 | |
| C1qb | complement component 1, q subcomponent, beta polypeptide | 0.044 | |
| Fam83h | family with sequence similarity 83, member H | 0.043 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.043 | |
| Cd53 | CD53 antigen | 0.040 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.040 | |
| Drd2 | dopamine receptor D2 | 0.039 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.039 | |
| Pax1 | paired box gene 1 | 0.038 | |
| C3ar1 | complement component 3a receptor 1 | 0.037 | |
| Ms4a6d | membrane-spanning 4-domains, subfamily A, member 6D | 0.036 | |
| Hoxa10 | homeobox A10 | 0.036 | |
| Il1r1 | interleukin 1 receptor, type I | 0.036 | |
| Scn7a | sodium channel, voltage-gated, type VII, alpha | 0.035 | |
| Cldn4 | claudin 4 | 0.035 | |
| Ctsd | cathepsin D | 0.034 | |
| Ahr | aryl-hydrocarbon receptor | 0.034 | |
| Fgf9 | fibroblast growth factor 9 | 0.034 | |
| Ctsc | cathepsin C | 0.034 | |
| Emr1 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 0.033 | |
| Ly86 | lymphocyte antigen 86 | 0.033 | |
| Mndal | myeloid nuclear differentiation antigen like | 0.033 | |
| Lgmn | legumain | 0.032 | |
| Ccl6 | chemokine (C-C motif) ligand 6 | 0.032 | |
| H2afx | H2A histone family, member X | 0.032 | |
| Lyz2 | lysozyme 2 | 0.032 | |
| Foxa2 | forkhead box A2 | 0.031 | |
| Foxc1 | forkhead box C1 | 0.031 | |
| Gata4 | GATA binding protein 4 | 0.031 | |
| Lrp10 | low-density lipoprotein receptor-related protein 10 | 0.030 | |
| Dlk1 | delta-like 1 homolog (Drosophila) | 0.029 | |
| C77080 | expressed sequence C77080 | 0.029 | |
| C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.029 | |
| Egfr | epidermal growth factor receptor | 0.029 | |
| Anapc1 | anaphase promoting complex subunit 1 | 0.029 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.029 | |
| Anxa1 | annexin A1 | 0.029 | |
| Crb3 | crumbs homolog 3 (Drosophila) | 0.028 | |
| Gbp2 | guanylate binding protein 2 | 0.028 | |
| Cldn3 | claudin 3 | 0.027 | |
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.027 | |
| G6pc | glucose-6-phosphatase, catalytic | 0.027 | |
| Slc34a2 | solute carrier family 34 (sodium phosphate), member 2 | 0.027 | |
| C1qc | complement component 1, q subcomponent, C chain | 0.026 | |
| Hoxa5 | homeobox A5 | 0.026 | |
| Nodal | nodal | 0.026 | |
| Tnfrsf11a | tumor necrosis factor receptor superfamily, member 11a | 0.026 | |
| Mlph | melanophilin | 0.026 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.025 | |
| Pdzk1ip1 | PDZK1 interacting protein 1 | 0.025 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.025 | |
| Myt1 | myelin transcription factor 1 | 0.025 | |
| Mab21l2 | mab-21-like 2 (C. elegans) | 0.025 | |
| Epn1 | epsin 1 | 0.025 | |
| Grn | granulin | 0.025 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.025 | |
| Fgf10 | fibroblast growth factor 10 | 0.024 | |
| Hoxd9 | homeobox D9 | 0.024 | |
| Col14a1 | collagen, type XIV, alpha 1 | 0.024 | |
| Ppy | pancreatic polypeptide | 0.024 | |
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.023 | |
| Hoxc8 | homeobox C8 | 0.023 | |
| Lhx1 | LIM homeobox protein 1 | 0.022 | |
| Stat6 | signal transducer and activator of transcription 6 | 0.022 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.022 | |
| Htra3 | HtrA serine peptidase 3 | 0.022 | |
| Cav1 | caveolin 1, caveolae protein | 0.022 | |
| Col11a1 | collagen, type XI, alpha 1 | 0.022 | |
| Litaf | LPS-induced TN factor | 0.022 | |
| Cdon | cell adhesion molecule-related/down-regulated by oncogenes | 0.022 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.021 | |
| Scn8a | sodium channel, voltage-gated, type VIII, alpha | 0.021 | |
| Cd44 | CD44 antigen | 0.021 | |
| Pthlh | parathyroid hormone-like peptide | 0.021 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.021 | |
| Spock1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 | 0.021 |
Loading network...
Caenorhabditis elegans
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| bli-1 | Protein BLI-1 | 0.206 | |
| col-128 | Protein COL-128 | 0.065 | |
| sqt-1 | Protein SQT-1 | 0.061 | |
| CELE_E01G4.6 | Protein E01G4.6 | 0.059 | |
| grd-1 | Protein GRD-1 | 0.054 | |
| CELE_F10G7.10 | Protein F10G7.10 | 0.041 | |
| abts-3 | Protein ABTS-3 | 0.038 | |
| col-48 | Protein COL-48 | 0.037 | |
| CELE_ZK1025.2 | Protein ZK1025.2 | 0.036 | |
| clec-180 | Protein CLEC-180 | 0.034 | |
| CELE_ZK1025.3 | Protein ZK1025.3 | 0.032 | |
| osm-8 | Protein OSM-8 | 0.030 | |
| pghm-1 | Protein PGHM-1 | 0.028 | |
| bah-1 | Protein BAH-1 | 0.023 | |
| dpy-8 | Protein DPY-8 | 0.022 | |
| cpna-1 | Protein CPNA-1 | 0.020 | |
| grd-2 | Protein GRD-2 | 0.020 | |
| qua-1 | Protein QUA-1 | 0.020 | |
| clp-1 | Protein CLP-1 | 0.019 | |
| F58E6.13 | Protein F58E6.13 | 0.019 | |
| pqn-47 | Protein PQN-47 | 0.019 | |
| cdh-7 | Protein CDH-7 | 0.019 | |
| ZK180.6 | Protein ZK180.6 | 0.018 | |
| T06D8.1 | Protein T06D8.1 | 0.017 | |
| CELE_B0280.7 | Protein B0280.7 | 0.017 | |
| sqt-2 | Protein SQT-2 | 0.017 | |
| pgal-1 | Protein PGAL-1 | 0.016 | |
| CELE_Y46G5A.29 | Protein Y46G5A.29 | 0.016 | |
| CELE_T06G6.6 | Protein T06G6.6 | 0.015 | |
| Y54E5A.7 | Protein Y54E5A.7 | 0.015 | |
| R07B1.5 | Protein R07B1.5 | 0.015 | |
| dmd-9 | Protein DMD-9 | 0.015 | |
| Y17G7B.10 | Protein Y17G7B.10 | 0.015 | |
| F13B6.1 | Protein F13B6.1 | 0.014 | |
| acdh-6 | Protein ACDH-6 | 0.014 | |
| C02F4.4 | Protein C02F4.4 | 0.013 | |
| dao-4 | Protein DAO-4 | 0.013 | |
| CELE_ZK337.2 | Protein ZK337.2 | 0.013 | |
| Y37E3.1 | Protein Y37E3.1 | 0.013 | |
| CELE_C54F6.3 | Protein C54F6.3 | 0.013 | |
| abu-13 | Protein ABU-13 | 0.013 | |
| CELE_C32H11.8 | Protein C32H11.8 | 0.013 | |
| CELE_Y37H9A.3 | Protein Y37H9A.3 | 0.012 | |
| dpy-5 | Protein DPY-5 | 0.012 | |
| CELE_T23F6.5 | Protein T23F6.5 | 0.012 | |
| CELE_F32A7.5 | Protein F32A7.5 | 0.012 | |
| col-38 | Protein COL-38 | 0.011 | |
| F49E2.5 | Protein F49E2.5 | 0.011 | |
| mam-4 | Protein MAM-4 | 0.011 | |
| F55C10.4 | Protein F55C10.4 | 0.011 | |
| CELE_Y11D7A.5 | Protein Y11D7A.5 | 0.011 | |
| zer-1 | Protein ZER-1 | 0.011 | |
| T16G1.2 | Protein T16G1.2 | 0.010 | |
| mlt-10 | Protein MLT-10 | 0.010 | |
| ZK836.2 | Protein ZK836.2 | 0.010 | |
| col-110 | Protein COL-110 | 0.010 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.988 | |
| NLRC4 | NLR family, CARD domain containing 4 | 0.902 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.780 | |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.699 | |
| CAPNS1 | calpain, small subunit 1 | 0.579 | |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.532 | |
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.404 | |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.369 | |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.245 | |
| PLAUR | plasminogen activator, urokinase receptor | 0.209 | |
| WRN | Werner syndrome, RecQ helicase-like | 0.158 | |
| PLAT | plasminogen activator, tissue | 0.154 | |
| CARD16 | caspase recruitment domain family, member 16 | 0.128 | |
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.117 | |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.116 | |
| PLAU | plasminogen activator, urokinase | 0.112 | |
| IFI16 | interferon, gamma-inducible protein 16 | 0.108 | |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.106 | |
| LRDD | leucine-rich repeats and death domain containing | 0.099 | |
| TADA3 | transcriptional adaptor 3 | 0.079 | |
| APLF | aprataxin and PNKP like factor | 0.060 | |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.058 | |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.058 | |
| SP100 | SP100 nuclear antigen | 0.041 | |
| APTX | aprataxin | 0.041 | |
| LDLR | low density lipoprotein receptor | 0.040 | |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.040 | |
| IL18 | interleukin 18 (interferon-gamma-inducing factor) | 0.039 | |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.036 | |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.034 | |
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.034 | |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.033 | |
| RAI1 | retinoic acid induced 1 | 0.032 | |
| HDAC1 | histone deacetylase 1 | 0.032 | |
| NMT1 | N-myristoyltransferase 1 | 0.031 | |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.029 | |
| TLR1 | toll-like receptor 1 | 0.028 | |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.027 | |
| KNG1 | kininogen 1 | 0.027 | |
| UNG | uracil-DNA glycosylase | 0.026 | |
| VTN | vitronectin | 0.025 | |
| KYNU | kynureninase | 0.025 | |
| ORM1 | orosomucoid 1 | 0.024 | |
| BCL2A1 | BCL2-related protein A1 | 0.024 | |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) | 0.023 | |
| AMT | aminomethyltransferase | 0.022 | |
| CD44 | CD44 molecule (Indian blood group) | 0.022 | |
| PYCARD | PYD and CARD domain containing | 0.022 | |
| CAST | calpastatin | 0.021 | |
| ANXA2 | annexin A2 | 0.021 | |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 0.020 | |
| PICK1 | protein interacting with PRKCA 1 | 0.020 | |
| HDGF | hepatoma-derived growth factor | 0.020 | |
| WFDC2 | WAP four-disulfide core domain 2 | 0.019 | |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.019 | |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.019 | |
| IL1A | interleukin 1, alpha | 0.018 | |
| CLEC2B | C-type lectin domain family 2, member B | 0.018 | |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.018 | |
| MUC4 | mucin 4, cell surface associated | 0.018 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.018 | |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.018 | |
| CARD6 | caspase recruitment domain family, member 6 | 0.017 | |
| FAS | Fas (TNF receptor superfamily, member 6) | 0.017 | |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 0.017 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.017 | |
| TRIM22 | tripartite motif containing 22 | 0.017 | |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.017 | |
| LIG3 | ligase III, DNA, ATP-dependent | 0.017 | |
| SQRDL | sulfide quinone reductase-like (yeast) | 0.016 | |
| APAF1 | apoptotic peptidase activating factor 1 | 0.016 | |
| GCGR | glucagon receptor | 0.016 | |
| TFR2 | transferrin receptor 2 | 0.016 | |
| TMPRSS11D | transmembrane protease, serine 11D | 0.015 | |
| PIGR | polymeric immunoglobulin receptor | 0.015 | |
| EMP1 | epithelial membrane protein 1 | 0.015 | |
| IL1B | interleukin 1, beta | 0.015 | |
| C4BPB | complement component 4 binding protein, beta | 0.015 | |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.015 | |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.015 | |
| MLKL | mixed lineage kinase domain-like | 0.014 | |
| CRP | C-reactive protein, pentraxin-related | 0.014 | |
| GJB1 | gap junction protein, beta 1, 32kDa | 0.014 | |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.014 | |
| USF1 | upstream transcription factor 1 | 0.014 | |
| ERG | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 0.014 | |
| PLG | plasminogen | 0.013 | |
| CTSS | cathepsin S | 0.013 | |
| CTSC | cathepsin C | 0.013 | |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.013 | |
| PRR15L | proline rich 15-like | 0.013 | |
| RDH16 | retinol dehydrogenase 16 (all-trans) | 0.013 | |
| TNS1 | tensin 1 | 0.013 | |
| HABP2 | hyaluronan binding protein 2 | 0.013 | |
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.012 | |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein | 0.012 | |
| CPN1 | carboxypeptidase N, polypeptide 1 | 0.012 | |
| VIL1 | villin 1 | 0.012 | |
| APOB | apolipoprotein B (including Ag(x) antigen) | 0.012 | |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 0.012 |