The network for 'regulation of organ formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of organ formation

Any process that modulates the rate, frequency or extent of organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.

Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Pitx2 paired-like homeodomain transcription factor 2 1.000
Fgf8 fibroblast growth factor 8 1.000
Otx2 orthodenticle homolog 2 (Drosophila) 0.999
Pax2 paired box gene 2 0.998
Foxc1 forkhead box C1 0.993
Fgfr3 fibroblast growth factor receptor 3 0.991
Tbx1 T-box 1 0.991
Fgfr2 fibroblast growth factor receptor 2 0.991
Emx2 empty spiracles homolog 2 (Drosophila) 0.989
Lhx3 LIM homeobox protein 3 0.985
Gli3 GLI-Kruppel family member GLI3 0.983
Lhx1 LIM homeobox protein 1 0.982
Hand2 heart and neural crest derivatives expressed transcript 2 0.977
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.970
Vangl2 vang-like 2 (van gogh, Drosophila) 0.968
Hoxd11 homeobox D11 0.954
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.949
Hoxa13 homeobox A13 0.913
Hoxa11 homeobox A11 0.909
Hoxa1 homeobox A1 0.899
Foxc2 forkhead box C2 0.894
Pax3 paired box gene 3 0.878
Wt1 Wilms tumor 1 homolog 0.863
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.847
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.845
Tcfap2a transcription factor AP-2, alpha 0.843
Bmp7 bone morphogenetic protein 7 0.830
Nodal nodal 0.815
Nog noggin 0.790
Pitx1 paired-like homeodomain transcription factor 1 0.787
Pax6 paired box gene 6 0.785
Gli2 GLI-Kruppel family member GLI2 0.761
Gsc goosecoid homeobox 0.728
Hand1 heart and neural crest derivatives expressed transcript 1 0.722
Tbx3 T-box 3 0.720
Sox2 SRY-box containing gene 2 0.708
En1 engrailed 1 0.694
Bmp4 bone morphogenetic protein 4 0.653
Kiss1 KiSS-1 metastasis-suppressor 0.650
Hoxd13 homeobox D13 0.637
Hoxa2 homeobox A2 0.627
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.627
Sall4 sal-like 4 (Drosophila) 0.589
Fgfr1 fibroblast growth factor receptor 1 0.558
Emx1 empty spiracles homolog 1 (Drosophila) 0.550
Tcf21 transcription factor 21 0.549
Foxh1 forkhead box H1 0.524
Msx2 homeobox, msh-like 2 0.519
Tcf15 transcription factor 15 0.514
Gdnf glial cell line derived neurotrophic factor 0.503
Dok1 docking protein 1 0.498
Gata4 GATA binding protein 4 0.488
Wnt3a wingless-related MMTV integration site 3A 0.455
Pax8 paired box gene 8 0.446
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.430
Gja5 gap junction protein, alpha 5 0.413
Fgf9 fibroblast growth factor 9 0.409
Chrd chordin 0.390
Isl1 ISL1 transcription factor, LIM/homeodomain 0.385
Tbx2 T-box 2 0.378
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.373
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.369
Lmx1b LIM homeobox transcription factor 1 beta 0.366
Prrx2 paired related homeobox 2 0.351
Amhr2 anti-Mullerian hormone type 2 receptor 0.347
Grb2 growth factor receptor bound protein 2 0.345
Msx1 homeobox, msh-like 1 0.342
Tbx15 T-box 15 0.332
Gata6 GATA binding protein 6 0.330
Ntf3 neurotrophin 3 0.302
Smad6 MAD homolog 6 (Drosophila) 0.297
Prrx1 paired related homeobox 1 0.285
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.283
Tlx3 T-cell leukemia, homeobox 3 0.280
Otx1 orthodenticle homolog 1 (Drosophila) 0.280
Neurog1 neurogenin 1 0.278
Foxg1 forkhead box G1 0.274
Gbx2 gastrulation brain homeobox 2 0.273
Snai1 snail homolog 1 (Drosophila) 0.268
Alx4 aristaless-like homeobox 4 0.267
Fgf15 fibroblast growth factor 15 0.264
Pou3f3 POU domain, class 3, transcription factor 3 0.252
Pten phosphatase and tensin homolog 0.238
Zic3 zinc finger protein of the cerebellum 3 0.236
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.234
Pitx3 paired-like homeodomain transcription factor 3 0.230
Rarg retinoic acid receptor, gamma 0.224
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.224
Spry4 sprouty homolog 4 (Drosophila) 0.214
Smo smoothened homolog (Drosophila) 0.209
Chd7 chromodomain helicase DNA binding protein 7 0.207
Esrrb estrogen related receptor, beta 0.206
Hmx1 H6 homeobox 1 0.205
Foxf2 forkhead box F2 0.202
Pou4f3 POU domain, class 4, transcription factor 3 0.201
Efna2 ephrin A2 0.198
Sox9 SRY-box containing gene 9 0.193
Spry2 sprouty homolog 2 (Drosophila) 0.191
Sim2 single-minded homolog 2 (Drosophila) 0.191
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
dpp decapentaplegic 0.991
ci cubitus interruptus 0.870
Egfr Epidermal growth factor receptor 0.698
en engrailed 0.692
hh hedgehog 0.646
eya eyes absent 0.506
H Hairless 0.499
wg wingless 0.408
hth homothorax 0.337
sog short gastrulation 0.296
bnl branchless 0.284
argos CG4531 gene product from transcript CG4531-RA 0.275
stumps CG31317 gene product from transcript CG31317-RC 0.262
tin tinman 0.155
gro groucho 0.142
kni knirps 0.138
so sine oculis 0.133
grh grainy head 0.128
tld tolloid 0.106
Ser Serrate 0.100
kn knot 0.092
pnr pannier 0.086
arm armadillo 0.086
twi twist 0.086
Dl Delta 0.085
aop anterior open 0.085
salm spalt major 0.081
wb wing blister 0.072
fng fringe 0.069
rib ribbon 0.058
sli slit 0.058
ptc patched 0.057
slp1 sloppy paired 1 0.055
CG8965 CG8965 gene product from transcript CG8965-RA 0.052
pan pangolin 0.052
rho rhomboid 0.050
Mad Mothers against dpp 0.049
tsg twisted gastrulation 0.049
pb proboscipedia 0.048
Dad Daughters against dpp 0.044
run runt 0.044
tkv thickveins 0.041
fj four-jointed 0.040
vg vestigial 0.038
if inflated 0.036
Med Medea 0.036
fz2 frizzled 2 0.036
dally division abnormally delayed 0.035
slou slouch 0.035
Ubx Ultrabithorax 0.035
abd-A abdominal A 0.035
sna snail 0.034
ex expanded 0.033
ush u-shaped 0.033
Lim1 CG11354 gene product from transcript CG11354-RA 0.032
brk brinker 0.031
sev sevenless 0.030
LanB1 CG7123 gene product from transcript CG7123-RA 0.030
srp serpent 0.030
pyr pyramus 0.029
Doc2 Dorsocross2 0.029
comm commissureless 0.029
sfl sulfateless 0.028
dsh dishevelled 0.027
zfh1 Zn finger homeodomain 1 0.026
vvl ventral veins lacking 0.026
sd scalloped 0.026
ap apterous 0.025
gcm glial cells missing 0.025
rtv retroactive 0.025
nrv2 nervana 2 0.025
btl breathless 0.024
tsh teashirt 0.023
Wnt2 Wnt oncogene analog 2 0.022
csw corkscrew 0.022
C15 CG7937 gene product from transcript CG7937-RA 0.022
tll tailless 0.022
ds dachsous 0.022
Lim3 CG10699 gene product from transcript CG10699-RB 0.021
al aristaless 0.020
crp cropped 0.020
Notum CG13076 gene product from transcript CG13076-RB 0.020
bowl brother of odd with entrails limited 0.020
lz lozenge 0.020
opa odd paired 0.020
noc no ocelli 0.020
ro rough 0.020
tan tantalus 0.019
shn schnurri 0.019
Mrtf Myocardin-related transcription factor 0.019
Traf4 TNF-receptor-associated factor 4 0.019
osa CG7467 gene product from transcript CG7467-RD 0.019
LanA Laminin A 0.019
Mlp84B Muscle LIM protein at 84B 0.018
Act42A Actin 42A 0.018
Sara Smad anchor for receptor activation 0.017
disco disconnected 0.017
Hmgcr HMG Coenzyme A reductase 0.016
byn brachyenteron 0.016
Irk2 Inwardly rectifying potassium channel 2 0.016
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
FGFR1 fibroblast growth factor receptor 1 0.996
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.995
FGFR2 fibroblast growth factor receptor 2 0.990
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.987
FGF1 fibroblast growth factor 1 (acidic) 0.976
CSNK1E casein kinase 1, epsilon 0.969
FOXD3 forkhead box D3 0.956
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.919
BMPR1A bone morphogenetic protein receptor, type IA 0.863
SOX10 SRY (sex determining region Y)-box 10 0.827
AXIN1 axin 1 0.782
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.724
LRP6 low density lipoprotein receptor-related protein 6 0.697
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.648
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.584
SP1 Sp1 transcription factor 0.528
APC adenomatous polyposis coli 0.502
LRRK2 leucine-rich repeat kinase 2 0.499
JAG1 jagged 1 0.494
TAOK1 TAO kinase 1 0.460
PLCG1 phospholipase C, gamma 1 0.447
NCOA2 nuclear receptor coactivator 2 0.443
CSNK1D casein kinase 1, delta 0.431
FGF2 fibroblast growth factor 2 (basic) 0.430
HCFC1 host cell factor C1 (VP16-accessory protein) 0.419
CTNNBIP1 catenin, beta interacting protein 1 0.370
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.363
CEP164 centrosomal protein 164kDa 0.310
NOG noggin 0.309
GATA4 GATA binding protein 4 0.307
SOX2 SRY (sex determining region Y)-box 2 0.269
WT1 Wilms tumor 1 0.261
ZNF512B zinc finger protein 512B 0.260
MYST2 MYST histone acetyltransferase 2 0.253
MDFI MyoD family inhibitor 0.239
NOTCH3 notch 3 0.237
BTRC beta-transducin repeat containing 0.219
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.200
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.183
FRS2 fibroblast growth factor receptor substrate 2 0.182
PAX3 paired box 3 0.175
FSTL1 follistatin-like 1 0.172
GLIS2 GLIS family zinc finger 2 0.171
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.151
GSK3B glycogen synthase kinase 3 beta 0.146
TCF4 transcription factor 4 0.146
EP300 E1A binding protein p300 0.146
GABPA GA binding protein transcription factor, alpha subunit 60kDa 0.123
NOSTRIN nitric oxide synthase trafficker 0.120
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.116
FOXO1 forkhead box O1 0.115
ZNF205 zinc finger protein 205 0.110
FAM110A family with sequence similarity 110, member A 0.103
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.099
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.093
MAML1 mastermind-like 1 (Drosophila) 0.093
HOXA10 homeobox A10 0.092
FGF7 fibroblast growth factor 7 0.087
PIK3CB phosphoinositide-3-kinase, catalytic, beta polypeptide 0.087
HOXD13 homeobox D13 0.084
SOX11 SRY (sex determining region Y)-box 11 0.083
HOXD10 homeobox D10 0.078
SPRY2 sprouty homolog 2 (Drosophila) 0.074
SMAD7 SMAD family member 7 0.074
FGF8 fibroblast growth factor 8 (androgen-induced) 0.073
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.069
FZD8 frizzled homolog 8 (Drosophila) 0.066
DSP desmoplakin 0.066
MCC mutated in colorectal cancers 0.065
FZD1 frizzled homolog 1 (Drosophila) 0.060
PITX1 paired-like homeodomain 1 0.055
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.054
BAHD1 bromo adjacent homology domain containing 1 0.052
SMAD1 SMAD family member 1 0.051
ZFYVE9 zinc finger, FYVE domain containing 9 0.051
CREBBP CREB binding protein 0.050
FAM110C family with sequence similarity 110, member C 0.049
HTT huntingtin 0.049
FGF3 fibroblast growth factor 3 0.048
HMGA1 high mobility group AT-hook 1 0.048
HOXB9 homeobox B9 0.047
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.047
ATN1 atrophin 1 0.045
C9orf100 chromosome 9 open reading frame 100 0.045
NOTCH2 notch 2 0.044
LEF1 lymphoid enhancer-binding factor 1 0.044
EMD emerin 0.044
FGF4 fibroblast growth factor 4 0.043
ERG v-ets erythroblastosis virus E26 oncogene homolog (avian) 0.043
SMAD3 SMAD family member 3 0.043
FOXA1 forkhead box A1 0.042
EYA1 eyes absent homolog 1 (Drosophila) 0.040
FOXE1 forkhead box E1 (thyroid transcription factor 2) 0.040
GAB1 GRB2-associated binding protein 1 0.039
HOXB5 homeobox B5 0.039
HOXD9 homeobox D9 0.039
SOX1 SRY (sex determining region Y)-box 1 0.038
DLL1 delta-like 1 (Drosophila) 0.038
FGFR3 fibroblast growth factor receptor 3 0.038
CADM4 cell adhesion molecule 4 0.038
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Cxxc4 CXXC finger 4 0.310
Unc5b unc-5 homolog B (C. elegans) 0.251
P2rx6 purinergic receptor P2X, ligand-gated ion channel, 6 0.143
Mrgprf MAS-related GPR, member F 0.141
Sox13 SRY (sex determining region Y)-box 13 0.115
Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.098
Gtf2a1 general transcription factor IIA, 1 0.091
Pdyn prodynorphin 0.087
Fgf5 fibroblast growth factor 5 0.087
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.085
Prap1 proline-rich acidic protein 1 0.074
Rcvrn recoverin 0.073
Chrnb3 cholinergic receptor, nicotinic, beta 3 0.070
Myo1c myosin IC 0.067
Olr1867 olfactory receptor 1867 0.067
Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 0.066
Tgfbr3 transforming growth factor, beta receptor III 0.065
Nfib nuclear factor I/B 0.064
Syt9 synaptotagmin IX 0.062
RGD1309821 similar to KIAA1161 protein 0.062
Mcam melanoma cell adhesion molecule 0.061
Hsf4 heat shock transcription factor 4 0.060
Olfml2b olfactomedin-like 2B 0.059
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.058
Ky kyphoscoliosis peptidase 0.058
Gfra2 GDNF family receptor alpha 2 0.057
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.056
Adrb1 adrenergic, beta-1-, receptor 0.056
Myh9 myosin, heavy chain 9, non-muscle 0.056
Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.056
Kcng2 potassium voltage-gated channel, subfamily G, member 2 0.056
Masp1 mannan-binding lectin serine peptidase 1 0.055
Foxc2 forkhead box C2 0.055
Irs1 insulin receptor substrate 1 0.053
Phkg1 phosphorylase kinase, gamma 1 0.052
Ppard peroxisome proliferator-activated receptor delta 0.052
Glg1 golgi apparatus protein 1 0.052
Tnni1 troponin I type 1 (skeletal, slow) 0.052
Ebf1 early B-cell factor 1 0.051
Gja3 gap junction protein, alpha 3 0.051
Tas2r119 taste receptor, type 2, member 119 0.051
Pde3a phosphodiesterase 3A, cGMP inhibited 0.049
Slc6a18 solute carrier family 6, member 18 0.049
Gper G protein-coupled estrogen receptor 1 0.048
Fgf18 fibroblast growth factor 18 0.048
Slc13a1 solute carrier family 13 (sodium/sulfate symporters), member 1 0.048
Cst12 cystatin 12 0.047
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.046
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.045
Pga5 pepsinogen 5, group I 0.045
A2bp1 ataxin 2 binding protein 1 0.045
Smad7 SMAD family member 7 0.044
Cacng4 calcium channel, voltage-dependent, gamma subunit 4 0.043
F13a1 coagulation factor XIII, A1 polypeptide 0.043
Ednra endothelin receptor type A 0.042
Ccdc102a coiled-coil domain containing 102A 0.041
Acvr1 activin A receptor, type I 0.040
Lamc1 laminin, gamma 1 0.040
Znf503 zinc finger protein 503 0.040
Gdnf glial cell derived neurotrophic factor 0.040
Bdkrb2 bradykinin receptor B2 0.040
Sod3 superoxide dismutase 3, extracellular 0.039
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.038
Dmd dystrophin 0.037
Cacng7 calcium channel, voltage-dependent, gamma subunit 7 0.037
Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 0.037
Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 0.036
Paqr8 progestin and adipoQ receptor family member VIII 0.036
Vegp1 von Ebners gland protein 1 0.035
Trim66 tripartite motif-containing 66 0.035
Prok1 prokineticin 1 0.035
Synpo synaptopodin 0.034
Tgfb2 transforming growth factor, beta 2 0.034
Syt8 synaptotagmin VIII 0.034
Prokr1 prokineticin receptor 1 0.034
Kcnv1 potassium channel, subfamily V, member 1 0.034
siat7D alpha-2,6-sialyltransferase ST6GalNAc IV 0.033
Hist1h4m histone cluster 1, H4m 0.033
Cdh6 cadherin 6 0.033
Stk11 serine/threonine kinase 11 0.033
Slc22a2 solute carrier family 22 (organic cation transporter), member 2 0.033
Madcam1 mucosal vascular addressin cell adhesion molecule 1 0.032
Hoxb7 homeo box B7 0.032
Pdc phosducin 0.032
Stx2 syntaxin 2 0.031
Ucn2 urocortin 2 0.031
Cpxm2 carboxypeptidase X (M14 family), member 2 0.031
Hoxd9 homeo box D9 0.031
Map3k3 mitogen activated protein kinase kinase kinase 3 0.030
Pth2r parathyroid hormone 2 receptor 0.030
Foxs1 forkhead box S1 0.030
Podxl podocalyxin-like 0.030
Mybphl myosin binding protein H-like 0.030
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.029
Ltbp3 latent transforming growth factor beta binding protein 3 0.029
Robo1 roundabout homolog 1 (Drosophila) 0.029
Tead3 TEA domain family member 3 0.029
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.029
Dbh dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.029
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.029
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism