IMP
Process View
The network for 'myoblast differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
myoblast differentiation
The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 0.966 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.941 | |
| Pax3 | paired box gene 3 | 0.939 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.779 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.736 | |
| Id3 | inhibitor of DNA binding 3 | 0.733 | |
| Sox9 | SRY-box containing gene 9 | 0.731 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.708 | |
| Foxc1 | forkhead box C1 | 0.708 | |
| Mapk14 | mitogen-activated protein kinase 14 | 0.592 | |
| Pax2 | paired box gene 2 | 0.585 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.537 | |
| Nodal | nodal | 0.513 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.500 | |
| Hoxd13 | homeobox D13 | 0.486 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.463 | |
| En1 | engrailed 1 | 0.446 | |
| Tcf21 | transcription factor 21 | 0.428 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.424 | |
| Lhx1 | LIM homeobox protein 1 | 0.410 | |
| Rarg | retinoic acid receptor, gamma | 0.399 | |
| Foxf1a | forkhead box F1a | 0.353 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.351 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.342 | |
| Sox7 | SRY-box containing gene 7 | 0.341 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.341 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.334 | |
| Gdf3 | growth differentiation factor 3 | 0.327 | |
| Plau | plasminogen activator, urokinase | 0.327 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.319 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.317 | |
| Tcfap2c | transcription factor AP-2, gamma | 0.307 | |
| Pthlh | parathyroid hormone-like peptide | 0.289 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.286 | |
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.285 | |
| Prrx2 | paired related homeobox 2 | 0.273 | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.269 | |
| Tbx1 | T-box 1 | 0.268 | |
| Tbx3 | T-box 3 | 0.267 | |
| Pax6 | paired box gene 6 | 0.262 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.261 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.259 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.251 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.250 | |
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.246 | |
| Wnt4 | wingless-related MMTV integration site 4 | 0.243 | |
| Nanog | Nanog homeobox | 0.241 | |
| Gata3 | GATA binding protein 3 | 0.241 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.241 | |
| Wnt2b | wingless related MMTV integration site 2b | 0.223 | |
| Il7 | interleukin 7 | 0.223 | |
| Fgf8 | fibroblast growth factor 8 | 0.217 | |
| Sall3 | sal-like 3 (Drosophila) | 0.214 | |
| Hoxd11 | homeobox D11 | 0.213 | |
| Bmp7 | bone morphogenetic protein 7 | 0.207 | |
| Wt1 | Wilms tumor 1 homolog | 0.205 | |
| Nfatc2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.202 | |
| Col2a1 | collagen, type II, alpha 1 | 0.199 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.194 | |
| Ccl12 | chemokine (C-C motif) ligand 12 | 0.193 | |
| Nf1 | neurofibromatosis 1 | 0.192 | |
| Fzd8 | frizzled homolog 8 (Drosophila) | 0.187 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.186 | |
| Dll4 | delta-like 4 (Drosophila) | 0.181 | |
| Onecut1 | one cut domain, family member 1 | 0.178 | |
| Tcf3 | transcription factor 3 | 0.177 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.177 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.176 | |
| Shox2 | short stature homeobox 2 | 0.176 | |
| Dll1 | delta-like 1 (Drosophila) | 0.175 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.171 | |
| Sall4 | sal-like 4 (Drosophila) | 0.171 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.170 | |
| Ifng | interferon gamma | 0.169 | |
| Lyz2 | lysozyme 2 | 0.169 | |
| Lif | leukemia inhibitory factor | 0.168 | |
| Myod1 | myogenic differentiation 1 | 0.165 | |
| Casp1 | caspase 1 | 0.163 | |
| Otp | orthopedia homolog (Drosophila) | 0.161 | |
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.157 | |
| Tcf15 | transcription factor 15 | 0.157 | |
| Tbx15 | T-box 15 | 0.157 | |
| Irx5 | Iroquois related homeobox 5 (Drosophila) | 0.156 | |
| Gja3 | gap junction protein, alpha 3 | 0.155 | |
| Gfra1 | glial cell line derived neurotrophic factor family receptor alpha 1 | 0.153 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.152 | |
| Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.151 | |
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.150 | |
| Msx1 | homeobox, msh-like 1 | 0.149 | |
| Csf3 | colony stimulating factor 3 (granulocyte) | 0.149 | |
| Hrc | histidine rich calcium binding protein | 0.146 | |
| S100a6 | S100 calcium binding protein A6 (calcyclin) | 0.144 | |
| Rhbdl3 | rhomboid, veinlet-like 3 (Drosophila) | 0.142 | |
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.141 | |
| Hoxa13 | homeobox A13 | 0.141 | |
| Ddx60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.140 | |
| Tbx4 | T-box 4 | 0.139 | |
| Pax9 | paired box gene 9 | 0.138 | |
| Il1b | interleukin 1 beta | 0.135 | |
| Meox2 | mesenchyme homeobox 2 | 0.134 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 1.000 | |
| RB1 | retinoblastoma 1 | 0.976 | |
| NOTCH1 | notch 1 | 0.970 | |
| TTN | titin | 0.950 | |
| JAG1 | jagged 1 | 0.925 | |
| E2F1 | E2F transcription factor 1 | 0.589 | |
| HDAC4 | histone deacetylase 4 | 0.508 | |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.494 | |
| JUN | jun proto-oncogene | 0.488 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.446 | |
| SNTA1 | syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) | 0.409 | |
| ATF2 | activating transcription factor 2 | 0.358 | |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.308 | |
| MYH7B | myosin, heavy chain 7B, cardiac muscle, beta | 0.264 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.241 | |
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.237 | |
| TCF4 | transcription factor 4 | 0.167 | |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.156 | |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.143 | |
| CREBBP | CREB binding protein | 0.133 | |
| NOTCH3 | notch 3 | 0.131 | |
| ATF3 | activating transcription factor 3 | 0.130 | |
| INO80B | INO80 complex subunit B | 0.127 | |
| FBLN1 | fibulin 1 | 0.121 | |
| DUSP1 | dual specificity phosphatase 1 | 0.119 | |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.106 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.103 | |
| OBSL1 | obscurin-like 1 | 0.100 | |
| ITGB1BP3 | integrin beta 1 binding protein 3 | 0.096 | |
| EGLN3 | egl nine homolog 3 (C. elegans) | 0.077 | |
| PARVA | parvin, alpha | 0.062 | |
| DLL1 | delta-like 1 (Drosophila) | 0.061 | |
| MKL1 | megakaryoblastic leukemia (translocation) 1 | 0.061 | |
| SMAD4 | SMAD family member 4 | 0.061 | |
| RBL1 | retinoblastoma-like 1 (p107) | 0.061 | |
| MYOCD | myocardin | 0.061 | |
| TGFB3 | transforming growth factor, beta 3 | 0.057 | |
| HDAC9 | histone deacetylase 9 | 0.054 | |
| CPNE6 | copine VI (neuronal) | 0.053 | |
| AR | androgen receptor | 0.052 | |
| MAPK14 | mitogen-activated protein kinase 14 | 0.051 | |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.049 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.048 | |
| EP300 | E1A binding protein p300 | 0.046 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.045 | |
| FSTL1 | follistatin-like 1 | 0.045 | |
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.042 | |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.042 | |
| ARRB1 | arrestin, beta 1 | 0.039 | |
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.036 | |
| PTPRC | protein tyrosine phosphatase, receptor type, C | 0.036 | |
| IGF2R | insulin-like growth factor 2 receptor | 0.036 | |
| TMSB10 | thymosin beta 10 | 0.035 | |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.035 | |
| AHR | aryl hydrocarbon receptor | 0.035 | |
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.035 | |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.034 | |
| MYOG | myogenin (myogenic factor 4) | 0.034 | |
| JUND | jun D proto-oncogene | 0.034 | |
| MAML1 | mastermind-like 1 (Drosophila) | 0.033 | |
| EIF2C1 | eukaryotic translation initiation factor 2C, 1 | 0.032 | |
| DBP | D site of albumin promoter (albumin D-box) binding protein | 0.032 | |
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.032 | |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.031 | |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.031 | |
| ENG | endoglin | 0.031 | |
| GATA4 | GATA binding protein 4 | 0.030 | |
| SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.030 | |
| SMAD1 | SMAD family member 1 | 0.030 | |
| E2F5 | E2F transcription factor 5, p130-binding | 0.029 | |
| HIC1 | hypermethylated in cancer 1 | 0.028 | |
| CELF1 | CUGBP, Elav-like family member 1 | 0.027 | |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.027 | |
| GLIS2 | GLIS family zinc finger 2 | 0.026 | |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.026 | |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.026 | |
| RBL2 | retinoblastoma-like 2 (p130) | 0.026 | |
| NOTCH2 | notch 2 | 0.025 | |
| E2F2 | E2F transcription factor 2 | 0.025 | |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.025 | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.025 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.024 | |
| EGLN1 | egl nine homolog 1 (C. elegans) | 0.024 | |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.024 | |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.024 | |
| PSEN1 | presenilin 1 | 0.024 | |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.024 | |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.024 | |
| MKL2 | MKL/myocardin-like 2 | 0.023 | |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.022 | |
| APC | adenomatous polyposis coli | 0.022 | |
| RNF7 | ring finger protein 7 | 0.022 | |
| VEGFA | vascular endothelial growth factor A | 0.022 | |
| NOV | nephroblastoma overexpressed gene | 0.022 | |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.022 | |
| MEF2C | myocyte enhancer factor 2C | 0.022 | |
| MYOD1 | myogenic differentiation 1 | 0.021 | |
| CUX1 | cut-like homeobox 1 | 0.021 | |
| SMAD9 | SMAD family member 9 | 0.021 | |
| APP | amyloid beta (A4) precursor protein | 0.020 |