The network for 'positive regulation of neuroblast proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of neuroblast proliferation

Any process that activates or increases the rate of neuroblast proliferation.

Mus musculus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 1.000
Gli3 GLI-Kruppel family member GLI3 0.999
Shh sonic hedgehog 0.999
Pax3 paired box gene 3 0.997
Sox2 SRY-box containing gene 2 0.986
Hes1 hairy and enhancer of split 1 (Drosophila) 0.980
Pax2 paired box gene 2 0.979
Bmp4 bone morphogenetic protein 4 0.972
Otx2 orthodenticle homolog 2 (Drosophila) 0.967
Foxc1 forkhead box C1 0.965
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.959
Eya1 eyes absent 1 homolog (Drosophila) 0.959
Nog noggin 0.943
Gli2 GLI-Kruppel family member GLI2 0.922
Hand2 heart and neural crest derivatives expressed transcript 2 0.885
Emx1 empty spiracles homolog 1 (Drosophila) 0.883
Fgf8 fibroblast growth factor 8 0.864
Foxg1 forkhead box G1 0.852
Fgf10 fibroblast growth factor 10 0.850
Pitx2 paired-like homeodomain transcription factor 2 0.825
Hand1 heart and neural crest derivatives expressed transcript 1 0.805
Prrx1 paired related homeobox 1 0.783
Rarg retinoic acid receptor, gamma 0.781
Chd7 chromodomain helicase DNA binding protein 7 0.777
Fgfr1 fibroblast growth factor receptor 1 0.773
Isl1 ISL1 transcription factor, LIM/homeodomain 0.765
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.756
Tcfap2a transcription factor AP-2, alpha 0.755
Foxc2 forkhead box C2 0.738
Fzd8 frizzled homolog 8 (Drosophila) 0.731
Sox9 SRY-box containing gene 9 0.728
Smo smoothened homolog (Drosophila) 0.713
Bmp7 bone morphogenetic protein 7 0.660
Vegfa vascular endothelial growth factor A 0.638
Foxa2 forkhead box A2 0.619
Msx1 homeobox, msh-like 1 0.613
Lhx3 LIM homeobox protein 3 0.606
Rb1 retinoblastoma 1 0.589
Pax8 paired box gene 8 0.586
Tgfb2 transforming growth factor, beta 2 0.563
Ctnnb1 catenin (cadherin associated protein), beta 1 0.548
Jag1 jagged 1 0.523
Chrd chordin 0.497
Efnb2 ephrin B2 0.487
Nos3 nitric oxide synthase 3, endothelial cell 0.467
Sox18 SRY-box containing gene 18 0.461
Myod1 myogenic differentiation 1 0.444
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.443
Sall3 sal-like 3 (Drosophila) 0.401
Ephb2 Eph receptor B2 0.390
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.388
Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) 0.387
Pax6 paired box gene 6 0.385
Sox7 SRY-box containing gene 7 0.385
Dlx5 distal-less homeobox 5 0.377
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.364
Smad6 MAD homolog 6 (Drosophila) 0.363
Hoxd9 homeobox D9 0.358
Hmx3 H6 homeobox 3 0.357
Lmx1b LIM homeobox transcription factor 1 beta 0.352
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.339
Hoxd11 homeobox D11 0.331
Meox2 mesenchyme homeobox 2 0.324
Wnt5a wingless-related MMTV integration site 5A 0.321
Sox3 SRY-box containing gene 3 0.313
Nkx2-1 NK2 homeobox 1 0.313
Msx2 homeobox, msh-like 2 0.306
Hoxa1 homeobox A1 0.294
Insm1 insulinoma-associated 1 0.286
Mitf microphthalmia-associated transcription factor 0.284
Flt4 FMS-like tyrosine kinase 4 0.281
Tbx1 T-box 1 0.266
Emx2 empty spiracles homolog 2 (Drosophila) 0.259
Hoxa2 homeobox A2 0.257
Fzd1 frizzled homolog 1 (Drosophila) 0.255
Pitx1 paired-like homeodomain transcription factor 1 0.253
Wnt4 wingless-related MMTV integration site 4 0.246
Pbx1 pre B-cell leukemia transcription factor 1 0.239
Jag2 jagged 2 0.233
Lmx1a LIM homeobox transcription factor 1 alpha 0.229
Tbx2 T-box 2 0.229
Tcf15 transcription factor 15 0.227
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.224
Hoxa10 homeobox A10 0.210
Tcfap2c transcription factor AP-2, gamma 0.207
Hoxd3 homeobox D3 0.205
Gbx2 gastrulation brain homeobox 2 0.190
Notch2 Notch gene homolog 2 (Drosophila) 0.183
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.182
Snai1 snail homolog 1 (Drosophila) 0.178
Dll1 delta-like 1 (Drosophila) 0.178
Pax9 paired box gene 9 0.168
Ednrb endothelin receptor type B 0.168
Pdgfb platelet derived growth factor, B polypeptide 0.161
Amh anti-Mullerian hormone 0.161
Tyr tyrosinase 0.160
Gas1 growth arrest specific 1 0.159
Gopc golgi associated PDZ and coiled-coil motif containing 0.158
Gata4 GATA binding protein 4 0.158
Efnb1 ephrin B1 0.156
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
E(spl) Enhancer of split 0.638
HLHmgamma E(spl) region transcript mgamma 0.361
dsh dishevelled 0.355
HLHmdelta E(spl) region transcript mdelta 0.350
HLHm7 E(spl) region transcript m7 0.227
H Hairless 0.107
HLHm5 E(spl) region transcript m5 0.079
nmo nemo 0.065
wg wingless 0.065
N Notch 0.059
dpp decapentaplegic 0.057
malpha E(spl) region transcript malpha 0.048
Tom Twin of m4 0.038
HLHm3 E(spl) region transcript m3 0.035
m2 E(spl) region transcript m2 0.028
HLHmbeta E(spl) region transcript mbeta 0.026
ato atonal 0.025
Dl Delta 0.024
Su(H) Suppressor of Hairless 0.022
slp1 sloppy paired 1 0.022
eya eyes absent 0.021
m4 E(spl) region transcript m4 0.020
ci cubitus interruptus 0.019
sc scute 0.016
ed echinoid 0.016
trx trithorax 0.014
Fas2 Fasciclin 2 0.014
sktl skittles 0.014
klu klumpfuss 0.013
hth homothorax 0.013
gro groucho 0.012
dm diminutive 0.012
brat brain tumor 0.012
gwl greatwall 0.011
ttk tramtrack 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
SOS1 son of sevenless homolog 1 (Drosophila) 0.728
POU3F2 POU class 3 homeobox 2 0.627
PAX3 paired box 3 0.627
JAG1 jagged 1 0.590
NRP1 neuropilin 1 0.492
SNX9 sorting nexin 9 0.388
APC adenomatous polyposis coli 0.341
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.329
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.287
GRB2 growth factor receptor-bound protein 2 0.283
NOTCH3 notch 3 0.272
MAML1 mastermind-like 1 (Drosophila) 0.266
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.262
MEOX2 mesenchyme homeobox 2 0.199
DNM1 dynamin 1 0.188
SNAP25 synaptosomal-associated protein, 25kDa 0.171
KAT2B K(lysine) acetyltransferase 2B 0.168
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.158
FOXD3 forkhead box D3 0.156
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.146
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.141
EGLN1 egl nine homolog 1 (C. elegans) 0.137
EPAS1 endothelial PAS domain protein 1 0.137
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.133
ABI1 abl-interactor 1 0.133
RGS3 regulator of G-protein signaling 3 0.115
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.113
WASL Wiskott-Aldrich syndrome-like 0.109
EGLN3 egl nine homolog 3 (C. elegans) 0.106
ARHGAP31 Rho GTPase activating protein 31 0.095
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.092
ACTN2 actinin, alpha 2 0.089
PGF placental growth factor 0.087
FERMT2 fermitin family member 2 0.083
AR androgen receptor 0.079
KIAA1377 KIAA1377 0.078
MAP1A microtubule-associated protein 1A 0.075
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.074
LDOC1 leucine zipper, down-regulated in cancer 1 0.074
NCOA2 nuclear receptor coactivator 2 0.074
TCF4 transcription factor 4 0.071
SALL2 sal-like 2 (Drosophila) 0.070
AMPH amphiphysin 0.070
NCK1 NCK adaptor protein 1 0.066
GLIS2 GLIS family zinc finger 2 0.064
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1 0.063
SYNE1 spectrin repeat containing, nuclear envelope 1 0.060
BTRC beta-transducin repeat containing 0.060
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.059
ITSN1 intersectin 1 (SH3 domain protein) 0.057
CTTN cortactin 0.051
DNM2 dynamin 2 0.051
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.047
POU5F1 POU class 5 homeobox 1 0.047
KCTD4 potassium channel tetramerisation domain containing 4 0.046
TNIP2 TNFAIP3 interacting protein 2 0.046
LCMT1 leucine carboxyl methyltransferase 1 0.043
JUP junction plakoglobin 0.043
TBK1 TANK-binding kinase 1 0.043
CSNK1E casein kinase 1, epsilon 0.043
PSEN1 presenilin 1 0.043
AXIN1 axin 1 0.042
STC1 stanniocalcin 1 0.042
PPARG peroxisome proliferator-activated receptor gamma 0.041
SH3GL2 SH3-domain GRB2-like 2 0.040
PPP1R12A protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.039
MEMO1 mediator of cell motility 1 0.039
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.038
VHL von Hippel-Lindau tumor suppressor 0.037
JAG2 jagged 2 0.036
MRPL20 mitochondrial ribosomal protein L20 0.036
IPO13 importin 13 0.035
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.034
EMD emerin 0.034
FOXO1 forkhead box O1 0.032
GSK3B glycogen synthase kinase 3 beta 0.032
SPTBN4 spectrin, beta, non-erythrocytic 4 0.032
SYNJ1 synaptojanin 1 0.032
KALRN kalirin, RhoGEF kinase 0.032
CENPF centromere protein F, 350/400kDa (mitosin) 0.031
MET met proto-oncogene (hepatocyte growth factor receptor) 0.031
RUNX1 runt-related transcription factor 1 0.031
LDLR low density lipoprotein receptor 0.031
SOX11 SRY (sex determining region Y)-box 11 0.030
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.030
SH3PXD2A SH3 and PX domains 2A 0.030
BBS10 Bardet-Biedl syndrome 10 0.029
MYST2 MYST histone acetyltransferase 2 0.029
NOTCH2 notch 2 0.028
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.027
CCDC141 coiled-coil domain containing 141 0.027
CDH5 cadherin 5, type 2 (vascular endothelium) 0.027
TSC22D4 TSC22 domain family, member 4 0.027
DDIT4 DNA-damage-inducible transcript 4 0.026
KIF18A kinesin family member 18A 0.026
NCOA6 nuclear receptor coactivator 6 0.026
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.026
DLL1 delta-like 1 (Drosophila) 0.026
NAP1L5 nucleosome assembly protein 1-like 5 0.025
LHX2 LIM homeobox 2 0.025
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism