The network for 'ureteric bud development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ureteric bud development

The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.

Mus musculus
Name Description Probability Func Analog Organism
Foxc1 forkhead box C1 1.000
Pax2 paired box gene 2 1.000
Shh sonic hedgehog 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Lhx1 LIM homeobox protein 1 1.000
Pax8 paired box gene 8 1.000
Wt1 Wilms tumor 1 homolog 1.000
Gli2 GLI-Kruppel family member GLI2 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Hoxd11 homeobox D11 1.000
Bmp4 bone morphogenetic protein 4 1.000
Foxc2 forkhead box C2 0.999
Fgf8 fibroblast growth factor 8 0.999
Nos3 nitric oxide synthase 3, endothelial cell 0.999
Emx2 empty spiracles homolog 2 (Drosophila) 0.999
Bcl2 B-cell leukemia/lymphoma 2 0.998
Bmp7 bone morphogenetic protein 7 0.997
Pbx1 pre B-cell leukemia transcription factor 1 0.997
Hoxa11 homeobox A11 0.996
Pten phosphatase and tensin homolog 0.996
Ret ret proto-oncogene 0.995
Gdnf glial cell line derived neurotrophic factor 0.995
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.994
Fgfr1 fibroblast growth factor receptor 1 0.994
Prrx1 paired related homeobox 1 0.994
Rarg retinoic acid receptor, gamma 0.994
Eya1 eyes absent 1 homolog (Drosophila) 0.992
Sox2 SRY-box containing gene 2 0.990
Hes1 hairy and enhancer of split 1 (Drosophila) 0.990
Fgfr3 fibroblast growth factor receptor 3 0.987
Otx2 orthodenticle homolog 2 (Drosophila) 0.987
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.986
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.986
Msx1 homeobox, msh-like 1 0.985
Hand1 heart and neural crest derivatives expressed transcript 1 0.984
Hoxd9 homeobox D9 0.982
Tbx2 T-box 2 0.981
Wnt4 wingless-related MMTV integration site 4 0.981
Nog noggin 0.976
Hand2 heart and neural crest derivatives expressed transcript 2 0.974
Pax3 paired box gene 3 0.974
Tgfb2 transforming growth factor, beta 2 0.971
Pax6 paired box gene 6 0.967
Tcf21 transcription factor 21 0.966
Hoxa1 homeobox A1 0.965
Pitx2 paired-like homeodomain transcription factor 2 0.963
Prrx2 paired related homeobox 2 0.960
Hes5 hairy and enhancer of split 5 (Drosophila) 0.959
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.956
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.954
Hoxa5 homeobox A5 0.952
Ctnnb1 catenin (cadherin associated protein), beta 1 0.949
Hoxc8 homeobox C8 0.948
Ren1 renin 1 structural 0.942
Sox7 SRY-box containing gene 7 0.939
Tbx1 T-box 1 0.933
Gbx2 gastrulation brain homeobox 2 0.923
Sox9 SRY-box containing gene 9 0.919
Smad6 MAD homolog 6 (Drosophila) 0.917
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.899
Emx1 empty spiracles homolog 1 (Drosophila) 0.896
Gata6 GATA binding protein 6 0.893
Hoxb6 homeobox B6 0.892
Isl1 ISL1 transcription factor, LIM/homeodomain 0.888
Pou3f3 POU domain, class 3, transcription factor 3 0.884
Dlx5 distal-less homeobox 5 0.882
Nf1 neurofibromatosis 1 0.882
Foxd2 forkhead box D2 0.868
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.867
Wnt6 wingless-related MMTV integration site 6 0.866
Nkx2-1 NK2 homeobox 1 0.865
Tbx15 T-box 15 0.852
Vegfa vascular endothelial growth factor A 0.852
En1 engrailed 1 0.850
Col2a1 collagen, type II, alpha 1 0.844
Otx1 orthodenticle homolog 1 (Drosophila) 0.840
Flt4 FMS-like tyrosine kinase 4 0.837
Esr1 estrogen receptor 1 (alpha) 0.835
Twist1 twist homolog 1 (Drosophila) 0.834
Meox2 mesenchyme homeobox 2 0.831
Foxf2 forkhead box F2 0.831
Hoxa10 homeobox A10 0.814
Agtr1a angiotensin II receptor, type 1a 0.804
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.802
Lhx3 LIM homeobox protein 3 0.798
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.798
Wnt5a wingless-related MMTV integration site 5A 0.795
Rarb retinoic acid receptor, beta 0.794
Sox11 SRY-box containing gene 11 0.789
Fgf10 fibroblast growth factor 10 0.788
Hoxd13 homeobox D13 0.787
Grem1 gremlin 1 0.782
Ar androgen receptor 0.774
Efnb2 ephrin B2 0.770
Hoxd10 homeobox D10 0.768
Gas1 growth arrest specific 1 0.761
Jag1 jagged 1 0.761
Bnc1 basonuclin 1 0.752
Kit kit oncogene 0.749
Vangl2 vang-like 2 (van gogh, Drosophila) 0.739
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FGFR2 fibroblast growth factor receptor 2 0.999
SMAD1 SMAD family member 1 0.996
SMAD3 SMAD family member 3 0.996
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.985
FGF1 fibroblast growth factor 1 (acidic) 0.985
SMAD2 SMAD family member 2 0.983
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.964
FGFR1 fibroblast growth factor receptor 1 0.940
NRP1 neuropilin 1 0.697
BMPR1A bone morphogenetic protein receptor, type IA 0.694
EGR3 early growth response 3 0.669
FGF10 fibroblast growth factor 10 0.521
EGR2 early growth response 2 0.489
MEIS1 Meis homeobox 1 0.472
MEIS2 Meis homeobox 2 0.413
MSN moesin 0.388
EGR1 early growth response 1 0.378
PAX8 paired box 8 0.367
BMP2 bone morphogenetic protein 2 0.338
PLCG1 phospholipase C, gamma 1 0.314
FGF8 fibroblast growth factor 8 (androgen-induced) 0.291
CCNE1 cyclin E1 0.284
HOXB5 homeobox B5 0.282
RXRA retinoid X receptor, alpha 0.280
FSTL1 follistatin-like 1 0.278
NOG noggin 0.278
SKI v-ski sarcoma viral oncogene homolog (avian) 0.245
HOXA10 homeobox A10 0.219
TIMP3 TIMP metallopeptidase inhibitor 3 0.215
MEOX1 mesenchyme homeobox 1 0.210
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.196
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.189
BMP7 bone morphogenetic protein 7 0.179
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.174
THBS1 thrombospondin 1 0.172
COL2A1 collagen, type II, alpha 1 0.156
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.153
FGF2 fibroblast growth factor 2 (basic) 0.146
SMAD4 SMAD family member 4 0.142
WNT1 wingless-type MMTV integration site family, member 1 0.141
FGF3 fibroblast growth factor 3 0.137
FGF18 fibroblast growth factor 18 0.136
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.135
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.129
NKX2-1 NK2 homeobox 1 0.123
MAGED2 melanoma antigen family D, 2 0.116
SKIL SKI-like oncogene 0.115
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.114
MED25 mediator complex subunit 25 0.113
TGFBR1 transforming growth factor, beta receptor 1 0.103
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.101
CPE carboxypeptidase E 0.095
ADAM17 ADAM metallopeptidase domain 17 0.094
BMP4 bone morphogenetic protein 4 0.093
NOTCH1 notch 1 0.087
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.084
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.084
ENG endoglin 0.081
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.078
SRGN serglycin 0.075
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.075
PGF placental growth factor 0.073
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.073
CXXC5 CXXC finger protein 5 0.072
CREBBP CREB binding protein 0.072
FGF4 fibroblast growth factor 4 0.066
EID1 EP300 interacting inhibitor of differentiation 1 0.063
WNT7A wingless-type MMTV integration site family, member 7A 0.062
PARVA parvin, alpha 0.062
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.062
SMAD9 SMAD family member 9 0.062
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.061
LBX1 ladybird homeobox 1 0.060
FGF7 fibroblast growth factor 7 0.057
FOS FBJ murine osteosarcoma viral oncogene homolog 0.055
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.053
VEGFA vascular endothelial growth factor A 0.051
SIM2 single-minded homolog 2 (Drosophila) 0.050
CSNK1E casein kinase 1, epsilon 0.046
NCOA1 nuclear receptor coactivator 1 0.044
PAX2 paired box 2 0.044
ECEL1 endothelin converting enzyme-like 1 0.043
TGFB2 transforming growth factor, beta 2 0.043
PTPRB protein tyrosine phosphatase, receptor type, B 0.042
CDC25B cell division cycle 25 homolog B (S. pombe) 0.041
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.041
FGFR3 fibroblast growth factor receptor 3 0.040
SFRP1 secreted frizzled-related protein 1 0.039
FOXA2 forkhead box A2 0.038
SOX1 SRY (sex determining region Y)-box 1 0.037
BCL2L1 BCL2-like 1 0.037
SMAD5 SMAD family member 5 0.036
MET met proto-oncogene (hepatocyte growth factor receptor) 0.036
ACAN aggrecan 0.034
TGFB3 transforming growth factor, beta 3 0.033
FOXF1 forkhead box F1 0.033
SOX2 SRY (sex determining region Y)-box 2 0.033
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.032
AQP5 aquaporin 5 0.032
HOXD10 homeobox D10 0.031
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Rattus norvegicus
Name Description Probability Func Analog Organism
Lhx1 LIM homeobox 1 0.299
Prph2 peripherin 2 0.290
Shox2 short stature homeobox 2 0.217
Twist2 twist homolog 2 (Drosophila) 0.164
Bmp6 bone morphogenetic protein 6 0.148
Runx1 runt-related transcription factor 1 0.146
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.138
Pgcp plasma glutamate carboxypeptidase 0.136
Unc5b unc-5 homolog B (C. elegans) 0.131
Efna5 ephrin A5 0.114
Col12a1 collagen, type XII, alpha 1 0.109
Clec11a C-type lectin domain family 11, member a 0.108
Adrb1 adrenergic, beta-1-, receptor 0.076
Mgst1 microsomal glutathione S-transferase 1 0.075
Pax8 paired box 8 0.074
Igfbp5 insulin-like growth factor binding protein 5 0.072
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.065
Dchs1 dachsous 1 (Drosophila) 0.062
Galr2 galanin receptor 2 0.059
Smad7 SMAD family member 7 0.059
C1qtnf3 C1q and tumor necrosis factor related protein 3 0.056
Ddr1 discoidin domain receptor tyrosine kinase 1 0.053
Grid2 glutamate receptor, ionotropic, delta 2 0.050
Vcan versican 0.048
Baiap2 BAI1-associated protein 2 0.047
Kl Klotho 0.046
Mcam melanoma cell adhesion molecule 0.046
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.044
Tpsb2 tryptase beta 2 0.043
Tgfbr2 transforming growth factor, beta receptor II 0.043
LOC64038 sertolin 0.041
Lrpap1 low density lipoprotein receptor-related protein associated protein 1 0.041
Slit3 slit homolog 3 (Drosophila) 0.040
Prrx1 paired related homeobox 1 0.039
Efnb1 ephrin B1 0.039
RT1-DOa RT1 class II, locus DOa 0.038
Hoxc4 homeo box C4 0.038
Krt18 keratin 18 0.037
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.036
Igf2 insulin-like growth factor 2 0.034
Fut4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.033
Ghr growth hormone receptor 0.033
Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 0.032
Hoxb7 homeo box B7 0.032
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.032
Col9a1 collagen, type IX, alpha 1 0.032
Epas1 endothelial PAS domain protein 1 0.031
Gata6 GATA binding protein 6 0.030
Pdc phosducin 0.030
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.028
Nrg2 neuregulin 2 0.028
Agtr1a angiotensin II receptor, type 1a 0.028
Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 0.028
Foxe3 forkhead box E3 0.028
Lama5 laminin, alpha 5 0.027
Zic1 Zic family member 1 (odd-paired homolog, Drosophila) 0.026
Aqp2 aquaporin 2 (collecting duct) 0.026
Pou3f2 POU class 3 homeobox 2 0.025
Clcn4-2 chloride channel 4-2 0.025
Gjd2 gap junction protein, delta 2 0.025
Lims1 LIM and senescent cell antigen-like domains 1 0.024
Glra1 glycine receptor, alpha 1 0.024
Galr1 galanin receptor 1 0.023
Cxxc4 CXXC finger 4 0.023
Bmp15 bone morphogenetic protein 15 0.023
Acvr1 activin A receptor, type I 0.023
Clcnkb chloride channel Kb 0.023
P22k15 cystatin related protein 2 0.022
Map6 microtubule-associated protein 6 0.022
Ephx1 epoxide hydrolase 1, microsomal 0.022
Neurod1 neurogenic differentiation 1 0.022
Cyth3 cytohesin 3 0.022
Wnt6 wingless-type MMTV integration site family, member 6 0.022
Fgfr2 fibroblast growth factor receptor 2 0.022
Sod3 superoxide dismutase 3, extracellular 0.022
Ier3 immediate early response 3 0.021
Pvrl2 poliovirus receptor-related 2 0.021
Hrh1 histamine receptor H 1 0.021
Snap91 synaptosomal-associated protein 91 0.021
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.021
Igfbp3 insulin-like growth factor binding protein 3 0.021
Kcna6 potassium voltage gated channel, shaker related subfamily, member 6 0.021
Sardh sarcosine dehydrogenase 0.020
Six1 SIX homeobox 1 0.020
Sc65 synaptonemal complex protein SC65 0.020
Aqp4 aquaporin 4 0.020
Top1 topoisomerase (DNA) I 0.020
Tnc tenascin C 0.020
Sox17 SRY (sex determining region Y)-box 17 0.020
Sec14l2 SEC14-like 2 (S. cerevisiae) 0.019
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.019
Stx2 syntaxin 2 0.019
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.019
Pik3r3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.019
Bglap bone gamma-carboxyglutamate (gla) protein 0.019
Agtr2 angiotensin II receptor, type 2 0.019
Crygb crystallin, gamma B 0.019
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.018
Tcfap2b transcription factor AP-2 beta 0.018
Pax6 paired box 6 0.018
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism