The network for 'metanephric nephron morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

metanephric nephron morphogenesis

The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.

Mus musculus
Name Description Probability Func Analog Organism
Pax2 paired box gene 2 1.000
Shh sonic hedgehog 1.000
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Pitx2 paired-like homeodomain transcription factor 2 1.000
Fgf8 fibroblast growth factor 8 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Foxc1 forkhead box C1 1.000
Sox2 SRY-box containing gene 2 0.999
Pax3 paired box gene 3 0.999
Fgfr2 fibroblast growth factor receptor 2 0.999
Emx2 empty spiracles homolog 2 (Drosophila) 0.998
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.997
Foxc2 forkhead box C2 0.995
Rarg retinoic acid receptor, gamma 0.993
Fgfr1 fibroblast growth factor receptor 1 0.992
Lhx1 LIM homeobox protein 1 0.991
Lhx3 LIM homeobox protein 3 0.990
Tbx1 T-box 1 0.984
Pax6 paired box gene 6 0.983
Bmp4 bone morphogenetic protein 4 0.981
Nog noggin 0.980
Pax8 paired box gene 8 0.979
Lmx1b LIM homeobox transcription factor 1 beta 0.977
Isl1 ISL1 transcription factor, LIM/homeodomain 0.976
Lmx1a LIM homeobox transcription factor 1 alpha 0.975
Gdnf glial cell line derived neurotrophic factor 0.970
Otx1 orthodenticle homolog 1 (Drosophila) 0.969
Eya1 eyes absent 1 homolog (Drosophila) 0.968
Tcfap2a transcription factor AP-2, alpha 0.962
Fgf10 fibroblast growth factor 10 0.943
Gbx2 gastrulation brain homeobox 2 0.934
Emx1 empty spiracles homolog 1 (Drosophila) 0.916
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.913
Hand1 heart and neural crest derivatives expressed transcript 1 0.908
Hoxa1 homeobox A1 0.899
Rarb retinoic acid receptor, beta 0.896
Wnt4 wingless-related MMTV integration site 4 0.879
Msx1 homeobox, msh-like 1 0.877
Hoxd11 homeobox D11 0.831
Fgf3 fibroblast growth factor 3 0.816
Hes1 hairy and enhancer of split 1 (Drosophila) 0.799
Wnt3a wingless-related MMTV integration site 3A 0.793
Hoxd13 homeobox D13 0.792
Sall4 sal-like 4 (Drosophila) 0.782
Ctnnb1 catenin (cadherin associated protein), beta 1 0.774
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.773
Wt1 Wilms tumor 1 homolog 0.765
Tgfb2 transforming growth factor, beta 2 0.753
En1 engrailed 1 0.752
Lef1 lymphoid enhancer binding factor 1 0.746
Hoxa2 homeobox A2 0.745
Nos3 nitric oxide synthase 3, endothelial cell 0.744
Meox2 mesenchyme homeobox 2 0.734
Jag1 jagged 1 0.733
Esr1 estrogen receptor 1 (alpha) 0.732
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.725
Gli2 GLI-Kruppel family member GLI2 0.710
Pou3f3 POU domain, class 3, transcription factor 3 0.707
Ntf3 neurotrophin 3 0.684
Ret ret proto-oncogene 0.680
Msx2 homeobox, msh-like 2 0.679
Vegfa vascular endothelial growth factor A 0.676
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.658
Hand2 heart and neural crest derivatives expressed transcript 2 0.621
Pten phosphatase and tensin homolog 0.591
Hoxa3 homeobox A3 0.563
Sox9 SRY-box containing gene 9 0.546
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.535
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.529
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.523
T brachyury 0.519
Efnb2 ephrin B2 0.513
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.497
Gata4 GATA binding protein 4 0.493
Smo smoothened homolog (Drosophila) 0.486
Dlx5 distal-less homeobox 5 0.471
Tbx3 T-box 3 0.461
Bcl2 B-cell leukemia/lymphoma 2 0.455
Foxg1 forkhead box G1 0.439
Sox11 SRY-box containing gene 11 0.432
Hes5 hairy and enhancer of split 5 (Drosophila) 0.427
Prop1 paired like homeodomain factor 1 0.409
Tcfap2c transcription factor AP-2, gamma 0.388
Gsc goosecoid homeobox 0.386
Alx4 aristaless-like homeobox 4 0.385
Sox4 SRY-box containing gene 4 0.367
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.361
Wnt1 wingless-related MMTV integration site 1 0.350
Rxra retinoid X receptor alpha 0.348
Vangl2 vang-like 2 (van gogh, Drosophila) 0.347
Onecut1 one cut domain, family member 1 0.345
Hoxa11 homeobox A11 0.340
Bmp7 bone morphogenetic protein 7 0.309
Hoxa13 homeobox A13 0.302
Twist2 twist homolog 2 (Drosophila) 0.300
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.297
Foxd2 forkhead box D2 0.296
Gata3 GATA binding protein 3 0.295
Lhx9 LIM homeobox protein 9 0.295
Lama5 laminin, alpha 5 0.278
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
EGR3 early growth response 3 0.953
EGR1 early growth response 1 0.916
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.890
EGR2 early growth response 2 0.770
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.696
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.580
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.573
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.495
FOS FBJ murine osteosarcoma viral oncogene homolog 0.339
LAT linker for activation of T cells 0.290
MEOX1 mesenchyme homeobox 1 0.284
NKX2-1 NK2 homeobox 1 0.243
SNAI1 snail homolog 1 (Drosophila) 0.223
GLIS2 GLIS family zinc finger 2 0.192
TCF4 transcription factor 4 0.160
IER2 immediate early response 2 0.148
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.147
FSTL1 follistatin-like 1 0.141
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.122
APC adenomatous polyposis coli 0.104
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.099
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.083
SOX2 SRY (sex determining region Y)-box 2 0.077
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.047
BBS10 Bardet-Biedl syndrome 10 0.040
COL2A1 collagen, type II, alpha 1 0.036
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.035
PDGFA platelet-derived growth factor alpha polypeptide 0.034
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.029
CSNK1E casein kinase 1, epsilon 0.026
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.021
AXIN1 axin 1 0.020
NCOA2 nuclear receptor coactivator 2 0.018
PKP4 plakophilin 4 0.018
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.017
TAOK1 TAO kinase 1 0.016
BBS1 Bardet-Biedl syndrome 1 0.015
NGFR nerve growth factor receptor 0.015
ERBB2IP erbb2 interacting protein 0.015
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.014
ZFYVE9 zinc finger, FYVE domain containing 9 0.014
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.013
FGFR1 fibroblast growth factor receptor 1 0.013
DUSP2 dual specificity phosphatase 2 0.013
CTNND1 catenin (cadherin-associated protein), delta 1 0.012
DUSP6 dual specificity phosphatase 6 0.012
CAV1 caveolin 1, caveolae protein, 22kDa 0.012
JUP junction plakoglobin 0.012
BMP2 bone morphogenetic protein 2 0.011
BMPR1A bone morphogenetic protein receptor, type IA 0.010
NPHP1 nephronophthisis 1 (juvenile) 0.010
GSK3B glycogen synthase kinase 3 beta 0.010
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.010
NOG noggin 0.010
EGFR epidermal growth factor receptor 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
LOC100365106 rCG32755-like 0.546
Parp9 poly (ADP-ribose) polymerase family, member 9 0.061
Gata3 GATA binding protein 3 0.043
C4b complement component 4B (Chido blood group) 0.032
Gjd2 gap junction protein, delta 2 0.026
Hoxc4 homeo box C4 0.020
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.020
Ddr1 discoidin domain receptor tyrosine kinase 1 0.018
Rnf213 ring finger protein 213 0.017
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.016
Gper G protein-coupled estrogen receptor 1 0.016
Ltbp3 latent transforming growth factor beta binding protein 3 0.015
Vwf von Willebrand factor 0.014
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.014
C1qc complement component 1, q subcomponent, C chain 0.013
Cngb1 cyclic nucleotide gated channel beta 1 0.013
Nos3 nitric oxide synthase 3, endothelial cell 0.012
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.012
Pdc phosducin 0.011
Hdac7 histone deacetylase 7 0.011
Il1r1 interleukin 1 receptor, type I 0.011
Sbp spermine binding protein 0.011
Masp1 mannan-binding lectin serine peptidase 1 0.011
Cd4 Cd4 molecule 0.010
LOC100362108 poly (ADP-ribose) polymerase family, member 10 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism