The network for 'exocrine pancreas development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

exocrine pancreas development

The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.

Mus musculus
Name Description Probability Func Analog Organism
Ins2 insulin II 0.983
Grb10 growth factor receptor bound protein 10 0.952
Cela3b chymotrypsin-like elastase family, member 3B 0.906
Hdac1 histone deacetylase 1 0.589
Sin3a transcriptional regulator, SIN3A (yeast) 0.567
Dnmt3a DNA methyltransferase 3A 0.544
Prss2 protease, serine, 2 0.525
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.486
Sycn syncollin 0.475
Igf2r insulin-like growth factor 2 receptor 0.435
Ctrb1 chymotrypsinogen B1 0.390
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.389
2210010C04Rik RIKEN cDNA 2210010C04 gene 0.365
Ptf1a pancreas specific transcription factor, 1a 0.357
Tcfap2a transcription factor AP-2, alpha 0.325
Ins1 insulin I 0.216
Reg2 regenerating islet-derived 2 0.212
Fgfr1 fibroblast growth factor receptor 1 0.210
Ctrl chymotrypsin-like 0.200
Cel carboxyl ester lipase 0.195
Insr insulin receptor 0.192
Cpa1 carboxypeptidase A1 0.179
Reg1 regenerating islet-derived 1 0.173
Hand2 heart and neural crest derivatives expressed transcript 2 0.158
Dll1 delta-like 1 (Drosophila) 0.150
Rbbp4 retinoblastoma binding protein 4 0.145
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.143
Clps colipase, pancreatic 0.141
Gfi1b growth factor independent 1B 0.122
Pax3 paired box gene 3 0.099
Gm13011 predicted gene 13011 0.092
Tff2 trefoil factor 2 (spasmolytic protein 1) 0.090
Acvr1 activin A receptor, type 1 0.087
Notch2 Notch gene homolog 2 (Drosophila) 0.081
Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) 0.077
Sox9 SRY-box containing gene 9 0.065
Htr3a 5-hydroxytryptamine (serotonin) receptor 3A 0.064
Rorb RAR-related orphan receptor beta 0.064
Lep leptin 0.063
Irs2 insulin receptor substrate 2 0.061
Onecut1 one cut domain, family member 1 0.061
Cuzd1 CUB and zona pellucida-like domains 1 0.058
Pnliprp1 pancreatic lipase related protein 1 0.050
Cd6 CD6 antigen 0.050
Zg16 zymogen granule protein 16 0.049
Fgfr2 fibroblast growth factor receptor 2 0.046
Pnliprp2 pancreatic lipase-related protein 2 0.045
Rnase1 ribonuclease, RNase A family, 1 (pancreatic) 0.044
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.041
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.041
Msx1 homeobox, msh-like 1 0.040
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.038
Ghr growth hormone receptor 0.037
Cela2a chymotrypsin-like elastase family, member 2A 0.036
Esr1 estrogen receptor 1 (alpha) 0.035
Pax6 paired box gene 6 0.035
Igf1r insulin-like growth factor I receptor 0.034
Zeb1 zinc finger E-box binding homeobox 1 0.033
Cav1 caveolin 1, caveolae protein 0.032
Phox2b paired-like homeobox 2b 0.032
Inhbc inhibin beta-C 0.031
Reg3a regenerating islet-derived 3 alpha 0.030
Gm10334 predicted gene 10334 0.030
Tcof1 Treacher Collins Franceschetti syndrome 1, homolog 0.030
Ubtf upstream binding transcription factor, RNA polymerase I 0.029
Lepr leptin receptor 0.028
Prss3 protease, serine, 3 0.028
Dnmt3l DNA (cytosine-5-)-methyltransferase 3-like 0.027
Tff1 trefoil factor 1 0.027
Try5 trypsin 5 0.026
Gsc goosecoid homeobox 0.026
Ednra endothelin receptor type A 0.026
Foxo1 forkhead box O1 0.026
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.025
Tacr2 tachykinin receptor 2 0.025
Reg3d regenerating islet-derived 3 delta 0.024
Neurod1 neurogenic differentiation 1 0.024
Nos1 nitric oxide synthase 1, neuronal 0.024
Ctrc chymotrypsin C (caldecrin) 0.023
Pten phosphatase and tensin homolog 0.023
Mesp1 mesoderm posterior 1 0.023
Dmbt1 deleted in malignant brain tumors 1 0.023
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.022
Dscam Down syndrome cell adhesion molecule 0.021
Pnlip pancreatic lipase 0.021
Mogat2 monoacylglycerol O-acyltransferase 2 0.021
Parp1 poly (ADP-ribose) polymerase family, member 1 0.020
Disp1 dispatched homolog 1 (Drosophila) 0.020
Mta2 metastasis-associated gene family, member 2 0.020
Ghrl ghrelin 0.019
Insm1 insulinoma-associated 1 0.019
Pou2f2 POU domain, class 2, transcription factor 2 0.018
Arid3a AT rich interactive domain 3A (BRIGHT-like) 0.018
Prg2 proteoglycan 2, bone marrow 0.017
Mybbp1a MYB binding protein (P160) 1a 0.017
Chrd chordin 0.017
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.017
Serpina10 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 0.017
Shh sonic hedgehog 0.017
Dlk1 delta-like 1 homolog (Drosophila) 0.017
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
hoxc8a homeo box C8a 0.956
hoxb8a homeo box B8a 0.945
hoxc4a homeo box C4a 0.857
hoxb6b homeo box B6b 0.768
hoxb5a homeo box B5a 0.767
hoxb5b homeo box B5b 0.675
tp53 tumor protein p53 0.551
hoxb3a homeo box B3a 0.531
pax6b paired box gene 6b 0.523
dnmt3 DNA (cytosine-5-)-methyltransferase 3 0.423
ptf1a pancreas specific transcription factor, 1a 0.397
hoxc9a homeo box C9a 0.348
hoxb6a homeo box B6a 0.315
hoxc6a homeo box C6a 0.314
tbx2b T-box 2b 0.304
hoxb1b homeo box B1b 0.298
gpr126 G protein-coupled receptor 126 0.297
hoxa5a homeo box A5a 0.288
ahctf1 AT hook containing transcription factor 1 0.274
lhx1a LIM homeobox 1a 0.267
tbx1 T-box 1 0.236
sox1a SRY-box containing gene 1a 0.229
hoxd4a homeo box D4a 0.199
ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.194
hhex hematopoietically expressed homeobox 0.191
barhl2 BarH-like 2 0.178
hoxa9a homeo box A9a 0.168
mab21l2 mab-21-like 2 0.167
foxp2 forkhead box P2 0.160
foxa1 forkhead box A1 0.159
nkx2.1a NK2 homeobox 1a 0.155
cdh2 cadherin 2, neuronal 0.155
hoxa4a homeo box A4a 0.145
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.138
notch3 notch homolog 3 0.136
rx3 retinal homeobox gene 3 0.134
hhip hedgehog interacting protein 0.129
ptch1 patched 1 0.127
hlxb9la homeo box HB9 like a 0.126
slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 0.125
gbx2 gastrulation brain homeo box 2 0.114
hnf1ba HNF1 homeobox Ba 0.114
lef1 lymphocyte enhancer binding factor 1 0.108
dld deltaD 0.103
fgfr4 fibroblast growth factor receptor 4 0.103
dag1 dystroglycan 1 0.101
dbx1b developing brain homeobox 1b 0.099
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.099
six4b sine oculis homeobox homolog 4b 0.096
nkx2.1b NK2 homeobox 1b 0.096
dnmt5 DNA (cytosine-5-)-methyltransferase 5 0.094
pitx2 paired-like homeodomain transcription factor 2 0.094
eya1 eyes absent homolog 1 0.093
dlc deltaC 0.092
try trypsin 0.092
tgfbi transforming growth factor, beta-induced 0.092
pcdh10b protocadherin 10b 0.091
lmx1b.2 LIM homeobox transcription factor 1, beta 2 0.089
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.089
atoh1a atonal homolog 1a 0.088
nadl1.2 neural adhesion molecule L1.2 0.086
gdnf glial cell derived neurotrophic factor 0.084
wif1 wnt inhibitory factor 1 0.083
atoh1b atonal homolog 1b 0.079
isl1 islet1 0.077
stil TAL1 (SCL) interrupting locus 0.077
dhrs3a dehydrogenase/reductase (SDR family) member 3a 0.075
hoxd10a homeo box D10a 0.074
tbx22 T-box 22 0.074
alcama activated leukocyte cell adhesion molecule a 0.069
runx1 runt-related transcription factor 1 0.068
fgfr2 fibroblast growth factor receptor 2 0.068
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.068
hoxc5a homeo box C5a 0.067
gdf6a growth differentiation factor 6a 0.066
lhx5 LIM homeobox 5 0.066
tbl3 transducin (beta)-like 3 0.065
isl2a islet2a 0.063
nkx3.2 NK3 homeobox 2 0.062
twist1a twist1a 0.060
prox1 prospero-related homeobox gene 1 0.060
foxa2 forkhead box A2 0.059
dlx6a distal-less homeobox gene 6a 0.058
barx1 BarH-like homeobox 1 0.056
rbm19 RNA binding motif protein 19 0.056
gro1 groucho 1 0.054
hoxc1a homeo box C1a 0.054
emx3 empty spiracles homeobox 3 0.054
meis4.1a myeloid ecotropic viral integration site 4.1a 0.054
dmrt3a doublesex and mab-3 related transcription factor 3a 0.052
nppa natriuretic peptide precursor A 0.051
ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.051
dlx5a distal-less homeobox gene 5a 0.050
hoxb10a homeo box B10a 0.050
LOC100150924 DNA polymerase subunit gamma-1-like 0.049
igf1rb insulin-like growth factor 1b receptor 0.049
tpt1 tumor protein, translationally-controlled 1 0.048
zgc:100927 zgc:100927 0.048
cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.048
hoxc6b homeo box C6b 0.047
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism