The network for 'cellular glucose homeostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular glucose homeostasis

A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment.

Mus musculus
Name Description Probability Func Analog Organism
Pax3 paired box gene 3 0.746
Ephb2 Eph receptor B2 0.727
Efnb2 ephrin B2 0.701
Lepr leptin receptor 0.619
Fgfr2 fibroblast growth factor receptor 2 0.594
Gab1 growth factor receptor bound protein 2-associated protein 1 0.448
Fgf8 fibroblast growth factor 8 0.416
Gli3 GLI-Kruppel family member GLI3 0.391
Nrxn3 neurexin III 0.382
Insr insulin receptor 0.373
Tgfb2 transforming growth factor, beta 2 0.338
Sox11 SRY-box containing gene 11 0.329
Pbx1 pre B-cell leukemia transcription factor 1 0.319
LOC100048884 novel member of the major urinary protein (Mup) gene family 0.309
Nos1 nitric oxide synthase 1, neuronal 0.292
Nf1 neurofibromatosis 1 0.286
Nrxn1 neurexin I 0.284
Onecut1 one cut domain, family member 1 0.284
Pim3 proviral integration site 3 0.272
Pax6 paired box gene 6 0.266
Cbln1 cerebellin 1 precursor protein 0.255
Ctnnb1 catenin (cadherin associated protein), beta 1 0.251
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.248
Foxa2 forkhead box A2 0.234
Nos3 nitric oxide synthase 3, endothelial cell 0.222
Rarg retinoic acid receptor, gamma 0.216
Pax8 paired box gene 8 0.199
Epha4 Eph receptor A4 0.198
Thra thyroid hormone receptor alpha 0.187
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.185
Fgfr1 fibroblast growth factor receptor 1 0.163
Mup5 major urinary protein 5 0.162
Alx3 aristaless-like homeobox 3 0.161
Mmp9 matrix metallopeptidase 9 0.150
Pim1 proviral integration site 1 0.142
Pparg peroxisome proliferator activated receptor gamma 0.140
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.134
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.132
Foxo1 forkhead box O1 0.131
Pnpla2 patatin-like phospholipase domain containing 2 0.130
Rdh10 retinol dehydrogenase 10 (all-trans) 0.130
Tpo thyroid peroxidase 0.129
Eya1 eyes absent 1 homolog (Drosophila) 0.128
Lef1 lymphoid enhancer binding factor 1 0.127
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.126
Sox4 SRY-box containing gene 4 0.126
Vegfa vascular endothelial growth factor A 0.125
Tbx3 T-box 3 0.123
Sim1 single-minded homolog 1 (Drosophila) 0.121
Thrb thyroid hormone receptor beta 0.120
Mup10 major urinary protein 10 0.120
Mup12 major urinary protein 12 0.119
T brachyury 0.117
Bmp4 bone morphogenetic protein 4 0.117
Cav1 caveolin 1, caveolae protein 0.117
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.116
Foxc1 forkhead box C1 0.115
Mup1 major urinary protein 1 0.115
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.115
Mup9 major urinary protein 9 0.114
Lep leptin 0.112
Mup19 major urinary protein 19 0.112
Amh anti-Mullerian hormone 0.109
Hnf4a hepatic nuclear factor 4, alpha 0.109
Cldn5 claudin 5 0.108
Slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 0.108
Dlx5 distal-less homeobox 5 0.107
Ilk integrin linked kinase 0.105
Mup7 major urinary protein 7 0.104
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.103
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.102
Rarb retinoic acid receptor, beta 0.097
Msx1 homeobox, msh-like 1 0.097
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.096
Isl1 ISL1 transcription factor, LIM/homeodomain 0.096
Ang2 angiogenin, ribonuclease A family, member 2 0.096
Bcl2 B-cell leukemia/lymphoma 2 0.095
Lyz2 lysozyme 2 0.093
Mup15 major urinary protein 15 0.093
Hoxa2 homeobox A2 0.091
Dock1 dedicator of cytokinesis 1 0.091
Prkaca protein kinase, cAMP dependent, catalytic, alpha 0.090
Efnb1 ephrin B1 0.089
Mup14 major urinary protein 14 0.089
Ntf3 neurotrophin 3 0.088
Rras Harvey rat sarcoma oncogene, subgroup R 0.088
Pkd1 polycystic kidney disease 1 homolog 0.087
Rpgrip1l Rpgrip1-like 0.086
Mup17 major urinary protein 17 0.084
Mup2 major urinary protein 2 0.084
Mup13 major urinary protein 13 0.083
Trp53 transformation related protein 53 0.083
Dlg1 discs, large homolog 1 (Drosophila) 0.083
Suds3 suppressor of defective silencing 3 homolog (S. cerevisiae) 0.082
Hes1 hairy and enhancer of split 1 (Drosophila) 0.082
Nrxn2 neurexin II 0.081
Epha2 Eph receptor A2 0.080
Uncx UNC homeobox 0.080
Ret ret proto-oncogene 0.080
Wnt1 wingless-related MMTV integration site 1 0.079
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 0.565
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.293
HLA-DMA major histocompatibility complex, class II, DM alpha 0.232
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.232
PLAU plasminogen activator, urokinase 0.215
HLA-DRA major histocompatibility complex, class II, DR alpha 0.206
CCNY cyclin Y 0.198
IL1R1 interleukin 1 receptor, type I 0.184
INCENP inner centromere protein antigens 135/155kDa 0.164
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.137
SMAD3 SMAD family member 3 0.120
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.112
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.108
HLA-DMB major histocompatibility complex, class II, DM beta 0.104
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.070
AXL AXL receptor tyrosine kinase 0.070
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.063
RANBP9 RAN binding protein 9 0.063
KAT2B K(lysine) acetyltransferase 2B 0.058
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.055
NME1 non-metastatic cells 1, protein (NM23A) expressed in 0.050
PLAUR plasminogen activator, urokinase receptor 0.047
CRHR1 corticotropin releasing hormone receptor 1 0.046
S100B S100 calcium binding protein B 0.044
NME2 non-metastatic cells 2, protein (NM23B) expressed in 0.041
SNAP25 synaptosomal-associated protein, 25kDa 0.037
SMAD2 SMAD family member 2 0.037
IRF2 interferon regulatory factor 2 0.037
PLAT plasminogen activator, tissue 0.036
SNAP23 synaptosomal-associated protein, 23kDa 0.036
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.034
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.033
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.033
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.032
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.032
RYR2 ryanodine receptor 2 (cardiac) 0.030
IL1RN interleukin 1 receptor antagonist 0.030
PSEN2 presenilin 2 (Alzheimer disease 4) 0.028
AKAP11 A kinase (PRKA) anchor protein 11 0.026
IL1RAP interleukin 1 receptor accessory protein 0.025
ATN1 atrophin 1 0.025
RNASE4 ribonuclease, RNase A family, 4 0.024
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.023
MKL1 megakaryoblastic leukemia (translocation) 1 0.022
MPDZ multiple PDZ domain protein 0.022
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.022
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.022
IL1B interleukin 1, beta 0.021
CREBBP CREB binding protein 0.021
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.021
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.020
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 0.019
MYOCD myocardin 0.019
PXN paxillin 0.018
NME3 non-metastatic cells 3, protein expressed in 0.018
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.018
HDAC3 histone deacetylase 3 0.017
SOCS1 suppressor of cytokine signaling 1 0.017
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.016
DAXX death-domain associated protein 0.016
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.016
HDAC1 histone deacetylase 1 0.015
IPO13 importin 13 0.015
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.015
VIM vimentin 0.013
NME4 non-metastatic cells 4, protein expressed in 0.013
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.013
SETD7 SET domain containing (lysine methyltransferase) 7 0.013
HIPK2 homeodomain interacting protein kinase 2 0.013
GABARAPL1 GABA(A) receptor-associated protein like 1 0.012
TRAF6 TNF receptor-associated factor 6 0.012
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.012
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.012
MYO16 myosin XVI 0.012
CARS cysteinyl-tRNA synthetase 0.012
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.012
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.012
YY1 YY1 transcription factor 0.012
ARRB2 arrestin, beta 2 0.011
MAPK10 mitogen-activated protein kinase 10 0.011
ULK1 unc-51-like kinase 1 (C. elegans) 0.011
HMGA1 high mobility group AT-hook 1 0.011
NCOR2 nuclear receptor corepressor 2 0.010
HCFC1 host cell factor C1 (VP16-accessory protein) 0.010
LMNA lamin A/C 0.010
PRDX1 peroxiredoxin 1 0.010
GJA1 gap junction protein, alpha 1, 43kDa 0.010
HIC1 hypermethylated in cancer 1 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ifitm3 interferon induced transmembrane protein 3 0.037
Lgals5 lectin, galactose binding, soluble 5 0.028
Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) 0.024
Timp1 TIMP metallopeptidase inhibitor 1 0.023
S100a11 S100 calcium binding protein A11 (calizzarin) 0.022
Foxa3 forkhead box A3 0.021
Lgals9 lectin, galactoside-binding, soluble, 9 0.020
Sftpd surfactant protein D 0.019
S100a10 S100 calcium binding protein A10 0.019
Myo1a myosin IA 0.018
Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 0.018
Apoa4 apolipoprotein A-IV 0.018
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.018
Flt1 FMS-related tyrosine kinase 1 0.018
Gja1 gap junction protein, alpha 1 0.018
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.018
Tcf21 transcription factor 21 0.018
Anxa2 annexin A2 0.017
Ccl2 chemokine (C-C motif) ligand 2 0.017
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.017
Smgb neonatal submandibular gland protein B 0.017
Foxa2 forkhead box A2 0.017
C8b complement component 8, beta polypeptide 0.017
Gpx3 glutathione peroxidase 3 0.017
Phkg1 phosphorylase kinase, gamma 1 0.017
Il1a interleukin 1 alpha 0.017
Cel carboxyl ester lipase 0.016
Prl8a2 prolactin family 8, subfamily a, member 2 0.016
Tbxa2r thromboxane A2 receptor 0.016
Krt15 keratin 15 0.016
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.016
Pzp pregnancy-zone protein 0.016
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.016
Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 0.016
Tpsab1 tryptase alpha/beta 1 0.016
LOC312273 Trypsin V-A 0.016
Htr6 5-hydroxytryptamine (serotonin) receptor 6 0.016
Litaf lipopolysaccharide-induced TNF factor 0.015
Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.015
Dll3 delta-like 3 (Drosophila) 0.015
Gad2 glutamate decarboxylase 2 0.015
Ghrl ghrelin/obestatin prepropeptide 0.015
Pnoc prepronociceptin 0.015
Ptgfr prostaglandin F receptor 0.015
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.015
Bglap bone gamma-carboxyglutamate (gla) protein 0.015
Chrnb2 cholinergic receptor, nicotinic, beta 2 (neuronal) 0.015
Gif gastric intrinsic factor 0.015
Cd80 Cd80 molecule 0.015
Gck glucokinase 0.015
Ccr1 chemokine (C-C motif) receptor 1 0.015
Galr2 galanin receptor 2 0.015
Mmp7 matrix metallopeptidase 7 0.015
Capn9 calpain 9 0.015
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.014
Col4a4 collagen, type IV, alpha 4 0.014
Dbp D site of albumin promoter (albumin D-box) binding protein 0.014
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.014
Grm7 glutamate receptor, metabotropic 7 0.014
Btbd2 BTB (POZ) domain containing 2 0.014
Oprd1 opioid receptor, delta 1 0.014
Chrna2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 0.014
Vom2r46 vomeronasal 2 receptor, 46 0.014
Csn1s2a casein alpha s2-like A 0.014
Crhbp corticotropin releasing hormone binding protein 0.014
Ppap2b phosphatidic acid phosphatase type 2B 0.014
Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 0.014
Psp parotid secretory protein 0.014
Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 0.014
RGD1310262 hypothetical LOC304650 0.014
Gip gastric inhibitory polypeptide 0.014
Tcfe2a transcription factor E2a 0.014
Slc22a8 solute carrier family 22 (organic anion transporter), member 8 0.014
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.014
Spt1 salivary protein 1 0.014
Lifr leukemia inhibitory factor receptor alpha 0.014
Rho rhodopsin 0.014
Drd3 dopamine receptor D3 0.014
Lrp3 low density lipoprotein receptor-related protein 3 0.014
Atp2a3 ATPase, Ca++ transporting, ubiquitous 0.014
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.014
Prl6a1 prolactin family 6, subfamily a, member 1 0.014
Pip prolactin induced protein 0.014
Pdgfb platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.014
Stat3 signal transducer and activator of transcription 3 0.014
Gata6 GATA binding protein 6 0.014
Dnase1l3 deoxyribonuclease 1-like 3 0.014
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.014
Prg2 proteoglycan 2, bone marrow 0.014
Cp ceruloplasmin 0.013
Cntn5 contactin 5 0.013
Naglt1 Na+ dependent glucose transporter 1 0.013
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.013
Rup2 urinary protein 2 0.013
Prl3d4 prolactin family 3, subfamily d, member 4 0.013
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.013
Flot2 flotillin 2 0.013
Slc10a2 solute carrier family 10 (sodium/bile acid cotransporter family), member 2 0.013
Icam1 intercellular adhesion molecule 1 0.013
Strn striatin, calmodulin binding protein 0.013
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
IRA1 Ira1p 0.026
PSY4 Psy4p 0.021
TPD3 Tpd3p 0.014
CDC55 Cdc55p 0.013
GPB2 Gpb2p 0.013
CNB1 Cnb1p 0.010