The network for 'regulation of intestinal epithelial structure maintenance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of intestinal epithelial structure maintenance

Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.

Name Description Probability Func Analog Organism
Neurod1 neurogenic differentiation 1 1.000
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.988
Shh sonic hedgehog 0.946
Isl1 ISL1 transcription factor, LIM/homeodomain 0.894
Pdx1 pancreatic and duodenal homeobox 1 0.848
Pax6 paired box gene 6 0.847
Otx2 orthodenticle homolog 2 (Drosophila) 0.843
Gata1 GATA binding protein 1 0.602
Onecut1 one cut domain, family member 1 0.592
Hand1 heart and neural crest derivatives expressed transcript 1 0.458
Mecom MDS1 and EVI1 complex locus 0.424
Pou4f2 POU domain, class 4, transcription factor 2 0.375
Msx1 homeobox, msh-like 1 0.366
Neurog2 neurogenin 2 0.335
Nkx3-2 NK3 homeobox 2 0.335
Neurog3 neurogenin 3 0.306
Foxc2 forkhead box C2 0.297
Kiss1 KiSS-1 metastasis-suppressor 0.292
Gsc goosecoid homeobox 0.262
Hoxa1 homeobox A1 0.252
Neurod4 neurogenic differentiation 4 0.242
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.235
Prph2 peripherin 2 0.211
Hoxd13 homeobox D13 0.203
En1 engrailed 1 0.202
Gata4 GATA binding protein 4 0.202
Gpr50 G-protein-coupled receptor 50 0.198
Tcf3 transcription factor 3 0.196
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.188
Lhx5 LIM homeobox protein 5 0.180
Hand2 heart and neural crest derivatives expressed transcript 2 0.152
Ptf1a pancreas specific transcription factor, 1a 0.148
Runx1t1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.143
Pax9 paired box gene 9 0.139
Alx3 aristaless-like homeobox 3 0.135
Ebf2 early B-cell factor 2 0.128
Insm1 insulinoma-associated 1 0.125
Dlx2 distal-less homeobox 2 0.119
Prrx2 paired related homeobox 2 0.119
Efna2 ephrin A2 0.119
Cbfa2t3 core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) 0.113
Foxd3 forkhead box D3 0.111
Srrm4 serine/arginine repetitive matrix 4 0.111
Ebf3 early B-cell factor 3 0.110
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.109
Sox11 SRY-box containing gene 11 0.103
Hoxd3 homeobox D3 0.101
Shox2 short stature homeobox 2 0.098
Snai1 snail homolog 1 (Drosophila) 0.096
Hba-x hemoglobin X, alpha-like embryonic chain in Hba complex 0.094
Arx aristaless related homeobox 0.091
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.086
Tgfb2 transforming growth factor, beta 2 0.085
Hoxd1 homeobox D1 0.085
Sox1 SRY-box containing gene 1 0.085
Prrx1 paired related homeobox 1 0.082
Tlx3 T-cell leukemia, homeobox 3 0.082
Pax3 paired box gene 3 0.079
Hbb-y hemoglobin Y, beta-like embryonic chain 0.079
Mab21l2 mab-21-like 2 (C. elegans) 0.079
Foxd2 forkhead box D2 0.078
Hoxb1 homeobox B1 0.078
Hbb-bh1 hemoglobin Z, beta-like embryonic chain 0.077
Prox1 prospero-related homeobox 1 0.077
Col22a1 collagen, type XXII, alpha 1 0.077
Pou3f2 POU domain, class 3, transcription factor 2 0.076
Dcc deleted in colorectal carcinoma 0.076
Lep leptin 0.074
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.073
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.073
Lhx9 LIM homeobox protein 9 0.072
Prph peripherin 0.071
Slc4a1 solute carrier family 4 (anion exchanger), member 1 0.070
Atoh1 atonal homolog 1 (Drosophila) 0.068
Tcfap2a transcription factor AP-2, alpha 0.068
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.067
Pitx2 paired-like homeodomain transcription factor 2 0.066
Hoxd12 homeobox D12 0.065
Rorb RAR-related orphan receptor beta 0.065
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.062
Hlx H2.0-like homeobox 0.061
Zfpm2 zinc finger protein, multitype 2 0.060
Lmo2 LIM domain only 2 0.060
Rhag Rhesus blood group-associated A glycoprotein 0.058
T brachyury 0.057
Trim10 tripartite motif-containing 10 0.056
Gdf11 growth differentiation factor 11 0.056
Fgf15 fibroblast growth factor 15 0.056
Sim2 single-minded homolog 2 (Drosophila) 0.055
Msx2 homeobox, msh-like 2 0.055
Myog myogenin 0.054
Pitx1 paired-like homeodomain transcription factor 1 0.054
Trim62 tripartite motif-containing 62 0.054
Nhlh1 nescient helix loop helix 1 0.054
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.053
Hoxb7 homeobox B7 0.052
Madcam1 mucosal vascular addressin cell adhesion molecule 1 0.052
Hoxa11 homeobox A11 0.050
Pou4f3 POU domain, class 4, transcription factor 3 0.049
Uncx UNC homeobox 0.049
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.046
PDX1 pancreatic and duodenal homeobox 1 0.040
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.036
CST9L cystatin 9-like 0.031
SLC28A1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 0.029
FTCD formiminotransferase cyclodeaminase 0.025
SLC34A1 solute carrier family 34 (sodium phosphate), member 1 0.025
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 0.022
SLC17A1 solute carrier family 17 (sodium phosphate), member 1 0.021
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 0.016
CCL1 chemokine (C-C motif) ligand 1 0.016
CRYAA crystallin, alpha A 0.015
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.015
SLC12A3 solute carrier family 12 (sodium/chloride transporters), member 3 0.014
GLYAT glycine-N-acyltransferase 0.014
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 0.014
ALPI alkaline phosphatase, intestinal 0.014
AQP7 aquaporin 7 0.013
ACPT acid phosphatase, testicular 0.013
TNNI1 troponin I type 1 (skeletal, slow) 0.013
AGXT2 alanine--glyoxylate aminotransferase 2 0.013
PAX4 paired box 4 0.012
GIP gastric inhibitory polypeptide 0.012
EID3 EP300 interacting inhibitor of differentiation 3 0.012
ACRV1 acrosomal vesicle protein 1 0.012
EXOC3L1 exocyst complex component 3-like 1 0.011
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.011
SCGN secretagogin, EF-hand calcium binding protein 0.011
VIL1 villin 1 0.011
THPO thrombopoietin 0.011
MIOX myo-inositol oxygenase 0.010
PKLR pyruvate kinase, liver and RBC 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism