The network for 'macromolecule biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

Name Description Probability Func Analog Organism
fgf3 fibroblast growth factor 3 0.995
notch1a notch homolog 1a 0.993
gli1 GLI-Kruppel family member 1 0.989
eya1 eyes absent homolog 1 0.988
spry4 sprouty (Drosophila) homolog 4 0.985
ctgf connective tissue growth factor 0.982
smo smoothened homolog (Drosophila) 0.982
pcna proliferating cell nuclear antigen 0.978
gata3 GATA-binding protein 3 0.977
rad21 RAD21 homolog (S. pombe) 0.972
bmp4 bone morphogenetic protein 4 0.970
chd chordin 0.965
foxi1 forkhead box I1 0.962
prdm1a PR domain containing 1a, with ZNF domain 0.962
tfap2a transcription factor AP-2 alpha 0.958
fgfr1a fibroblast growth factor receptor 1a 0.957
shha sonic hedgehog a 0.952
etv5b ets variant 5b 0.951
runx2b runt-related transcription factor 2b 0.949
evx1 even-skipped homeobox 1 0.949
wnt11r wingless-type MMTV integration site family, member 11, related 0.946
sox9a SRY-box containing gene 9a 0.941
hnf1ba HNF1 homeobox Ba 0.937
crabp2a cellular retinoic acid binding protein 2, a 0.937
hoxc4a homeo box C4a 0.929
myod1 myogenic differentiation 1 0.927
dlx5a distal-less homeobox gene 5a 0.918
isl1 islet1 0.911
gbx1 gastrulation brain homeobox 1 0.907
six1b sine oculis homeobox homolog 1b 0.904
pitx3 paired-like homeodomain transcription factor 3 0.904
neo1 neogenin 1 0.901
ndr2 nodal-related 2 0.892
lft1 lefty1 0.890
rx3 retinal homeobox gene 3 0.889
tp53 tumor protein p53 0.880
jag1b jagged 1b 0.876
dla deltaA 0.870
atoh7 atonal homolog 7 0.869
ccnd1 cyclin D1 0.868
pcdh18b protocadherin 18b 0.867
atoh1a atonal homolog 1a 0.864
dkk1b dickkopf 1b 0.863
myf5 myogenic factor 5 0.858
snai1b snail homolog 1b (Drosophila) 0.853
six3a sine oculis homeobox homolog 3a 0.849
col2a1a collagen type II, alpha-1a 0.846
btg2 B-cell translocation gene 2 0.845
gbx2 gastrulation brain homeo box 2 0.844
barx1 BarH-like homeobox 1 0.833
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.828
bmp2b bone morphogenetic protein 2b 0.828
cfl2l cofilin 2, like 0.828
irx4b iroquois homeobox protein 4b 0.825
dlb deltaB 0.821
fgf17 fibroblast growth factor 17 0.817
foxa2 forkhead box A2 0.812
cdx4 caudal type homeo box transcription factor 4 0.804
raraa retinoic acid receptor, alpha a 0.804
ret1 receptor tyrosine kinase 0.803
frem3 Fras1 related extracellular matrix 3 0.803
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.802
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.798
mbnl2 muscleblind-like 2 (Drosophila) 0.798
nfkbiaa nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a 0.794
gata6 GATA-binding protein 6 0.788
gpr126 G protein-coupled receptor 126 0.787
drl draculin 0.785
twist3 twist3 0.784
twist1b twist1b 0.780
mecom MDS1 and EVI1 complex locus 0.779
otpa orthopedia homolog a 0.778
rnf2 ring finger protein 2 0.778
fezf2 FEZ family zinc finger 2 0.775
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.774
arx aristaless related homeobox 0.774
fgf10a fibroblast growth factor 10a 0.769
ihha Indian hedgehog homolog a 0.755
dlx3b distal-less homeobox gene 3b 0.751
vegfaa vascular endothelial growth factor Aa 0.746
ntla no tail a 0.745
mafl v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L 0.739
tbx18 T-box 18 0.738
nkx2.3 NK2 transcription factor related 3 0.736
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.734
hand2 heart and neural crest derivatives expressed transcript 2 0.734
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.733
sox19a SRY-box containing gene 19a 0.727
setdb1b SET domain, bifurcated 1b 0.726
dmrt3a doublesex and mab-3 related transcription factor 3a 0.725
lhx1a LIM homeobox 1a 0.723
dld deltaD 0.722
ezh2 enhancer of zeste homolog 2 (Drosophila) 0.722
pax6a paired box gene 6a 0.720
tal1 T-cell acute lymphocytic leukemia 1 0.720
pdlim7 PDZ and LIM domain 7 0.719
top2a topoisomerase (DNA) II alpha 0.719
six4a sine oculis homeobox homolog 4a 0.718
LOC100151531 zinc finger protein Gfi-1b-like 0.718
fsta follistatin a 0.716
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
pha-4 Protein PHA-4 0.986
egl-18 Protein EGL-18 0.984
hlh-2 Protein HLH-2 0.808
vab-3 Protein VAB-3 0.716
D1081.8 Protein D1081.8 0.704
egl-27 Protein EGL-27 0.652
nhr-67 Protein NHR-67 0.650
iff-1 Protein IFF-1 0.639
his-5 Protein HIS-5 0.624
attf-2 Protein ATTF-2 0.594
pqn-59 Protein PQN-59 0.573
rpt-3 Protein RPT-3 0.571
eftu-2 Protein EFTU-2 0.558
unc-62 Protein UNC-62 0.556
rpn-1 Protein RPN-1 0.549
F53F10.2 Protein F53F10.2 0.548
eya-1 Protein EYA-1 0.541
his-31 Protein HIS-31 0.529
lmn-1 Protein LMN-1 0.528
his-64 Protein HIS-64 0.523
pas-4 Protein PAS-4 0.507
dbr-1 Protein DBR-1 0.501
CELE_W03F9.10 Protein W03F9.10 0.498
cam-1 Protein CAM-1 0.497
dlk-1 Protein DLK-1 0.484
ceh-20 Protein CEH-20 0.483
his-50 Protein HIS-50 0.461
his-52 Protein HIS-52 0.455
zip-7 Protein ZIP-7 0.448
rsa-2 Protein RSA-2 0.434
ifg-1 Protein IFG-1 0.432
csn-4 Protein CSN-4 0.426
lin-36 Protein LIN-36 0.422
npp-7 Protein NPP-7 0.418
his-46 Protein HIS-46 0.415
fkh-2 Protein FKH-2 0.413
F36D4.5 Protein F36D4.5 0.408
his-1 Protein HIS-1 0.403
eor-1 Protein EOR-1 0.399
hcp-3 Protein HCP-3 0.397
egl-45 Protein EGL-45 0.395
daf-3 Protein DAF-3 0.394
bet-1 Protein BET-1 0.390
CELE_F10G7.9 Protein F10G7.9 0.384
eif-3.D Protein EIF-3.D 0.384
skp-1 Protein SKP-1 0.379
fars-1 Protein FARS-1 0.377
peb-1 Protein PEB-1 0.376
daf-14 Protein DAF-14 0.374
C14C10.4 Protein C14C10.4 0.372
mig-32 Protein MIG-32 0.372
ztf-2 Protein ZTF-2 0.370
nud-1 Protein NUD-1 0.367
pie-1 Protein PIE-1 0.365
pbrm-1 Protein PBRM-1 0.364
rsp-1 Protein RSP-1 0.363
his-42 Protein HIS-42 0.361
daf-1 Protein DAF-1 0.354
eif-3.B Protein EIF-3.B 0.354
klp-15 Protein KLP-15 0.353
rps-2 Protein RPS-2 0.352
lin-11 Protein LIN-11 0.349
nol-1 Protein NOL-1 0.346
rpl-4 Protein RPL-4 0.344
pas-5 Protein PAS-5 0.344
R05F9.9 Protein R05F9.9 0.342
T28D9.4 Protein T28D9.4 0.336
let-502 Protein LET-502 0.336
mcm-7 Protein MCM-7 0.331
D2085.3 Protein D2085.3 0.329
egl-46 Protein EGL-46 0.329
glp-1 Protein GLP-1 0.324
unc-52 Protein UNC-52 0.320
hlh-1 Protein HLH-1 0.319
pry-1 Protein PRY-1 0.318
klp-7 Protein KLP-7 0.317
dsh-2 Protein DSH-2 0.317
his-16 Protein HIS-16 0.315
zyg-1 Protein ZYG-1 0.313
his-61 Protein HIS-61 0.312
hmg-1.2 Protein HMG-1.2 0.311
mig-6 Protein MIG-6 0.310
pabp-2 Protein PABP-2 0.310
lin-35 Protein LIN-35 0.309
F40F4.7 Protein F40F4.7 0.309
cfim-2 Protein CFIM-2 0.307
aap-1 Protein AAP-1 0.302
mix-1 Protein MIX-1 0.301
swsn-2.1 Protein SWSN-2.1 0.299
mes-4 Protein MES-4 0.295
his-45 Protein HIS-45 0.288
dpy-30 Protein DPY-30 0.288
T28F4.1 Protein T28F4.1 0.287
hcp-6 Protein HCP-6 0.286
lsm-1 Protein LSM-1 0.281
his-3 Protein HIS-3 0.280
sams-3 Protein SAMS-3 0.280
CELE_F17C11.10 Protein F17C11.10 0.278
egl-8 Protein EGL-8 0.277
elt-6 Protein ELT-6 0.276
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism