The network for 'positive regulation of muscle tissue development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of muscle tissue development

Any process that activates or increases the frequency, rate or extent of muscle tissue development.

Danio rerio
Name Description Probability Func Analog Organism
tbx1 T-box 1 0.820
fgf8a fibroblast growth factor 8 a 0.807
cdh2 cadherin 2, neuronal 0.720
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.635
gli1 GLI-Kruppel family member 1 0.565
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.551
notch1b notch homolog 1b 0.533
myod1 myogenic differentiation 1 0.465
sox9a SRY-box containing gene 9a 0.454
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.448
met met proto-oncogene (hepatocyte growth factor receptor) 0.444
gata6 GATA-binding protein 6 0.419
bmp4 bone morphogenetic protein 4 0.393
fgf17 fibroblast growth factor 17 0.392
has2 hyaluronan synthase 2 0.388
bmp2b bone morphogenetic protein 2b 0.325
tbx20 T-box 20 0.321
myf5 myogenic factor 5 0.307
hspb7 heat shock protein family, alpha-crystallin-related, b7 0.277
tbx5a T-box 5a 0.255
ptch2 patched 2 0.251
twist1a twist1a 0.233
sox9b SRY-box containing gene 9b 0.224
fgfr1a fibroblast growth factor receptor 1a 0.212
nkx2.5 NK2 transcription factor related 5 0.207
crabp2a cellular retinoic acid binding protein 2, a 0.204
wnt11r wingless-type MMTV integration site family, member 11, related 0.203
epha4a eph receptor A4a 0.198
lft1 lefty1 0.196
ptch1 patched 1 0.193
ihha Indian hedgehog homolog a 0.188
wnt4a wingless-type MMTV integration site family, member 4a 0.187
alcamb activated leukocyte cell adhesion molecule b 0.178
atp1b2b ATPase, Na+/K+ transporting, beta 2b polypeptide 0.176
wnt1 wingless-type MMTV integration site family, member 1 0.165
wnt8b wingless-type MMTV integration site family, member 8b 0.153
igfbp3 insulin-like growth factor binding protein 3 0.151
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.151
tbx2b T-box 2b 0.148
her7 hairy and enhancer of split related-7 0.145
wls wntless homolog (Drosophila) 0.136
hand2 heart and neural crest derivatives expressed transcript 2 0.136
alp alkaline phosphatase 0.135
foxp1b forkhead box P1b 0.135
egr2b early growth response 2b 0.133
pdlim7 PDZ and LIM domain 7 0.130
rhoub ras homolog gene family, member Ub 0.125
foxi1 forkhead box I1 0.122
dcc deleted in colorectal carcinoma 0.119
wif1 wnt inhibitory factor 1 0.118
gro1 groucho 1 0.117
mib mind bomb 0.116
acvr1b activin A receptor, type IB 0.115
wnt7aa wingless-type MMTV integration site family, member 7Aa 0.114
fgf10a fibroblast growth factor 10a 0.112
sfrp1a secreted frizzled-related protein 1a 0.109
osr1 odd-skipped related 1 (Drosophila) 0.105
wnt5b wingless-type MMTV integration site family, member 5b 0.104
wnt9a wingless-type MMTV integration site family, member 9A 0.104
neo1 neogenin 1 0.102
bmp2a bone morphogenetic protein 2a 0.102
lmo4a LIM domain only 4a 0.100
tbx18 T-box 18 0.096
mtp microsomal triglyceride transfer protein 0.094
flt4 fms-related tyrosine kinase 4 0.093
hnf1ba HNF1 homeobox Ba 0.093
pax3a paired box gene 3a 0.090
tfec transcription factor EC 0.090
gro2 groucho 2 0.089
etv5a ets variant 5a 0.088
klf4a Kruppel-like transcription factor 4a 0.088
bhlhe40 basic helix-loop-helix family, member e40 0.087
cobl cordon-bleu homolog (mouse) 0.086
gbx2 gastrulation brain homeo box 2 0.085
gata5 GATA-binding protein 5 0.085
wnt10a wingless-type MMTV integration site family, member 10a 0.085
fabp11a fatty acid binding protein 11a 0.084
per3 period homolog 3 (Drosophila) 0.081
id2a inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a 0.080
shha sonic hedgehog a 0.080
wnt3 wingless-type MMTV integration site family, member 3 0.079
sfrp5 secreted frizzled-related protein 5 0.076
rbfox1l RNA binding protein, fox-1 homolog (C. elegans) 1-like 0.075
ogg1 8-oxoguanine DNA glycosylase 0.075
wu:fv91b12 wu:fv91b12 0.074
kif23 kinesin family member 23 0.072
hspb1 heat shock protein, alpha-crystallin-related, 1 0.072
wnt7ba wingless-type MMTV integration site family, member 7Ba 0.072
m17 IL-6 subfamily cytokine M17 0.072
tnnt2a troponin T2a, cardiac 0.071
fgf24 fibroblast growth factor 24 0.071
mapk3 mitogen-activated protein kinase 3 0.070
per2 period homolog 2 (Drosophila) 0.070
hmx4 H6 family homeobox 4 0.069
og9x OG9 homeobox gene 0.069
ntn2 netrin 2 0.068
max myc-associated factor X 0.068
mapk1 mitogen-activated protein kinase 1 0.068
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.067
fgf3 fibroblast growth factor 3 0.066
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FGFR2 fibroblast growth factor receptor 2 0.999
FGF1 fibroblast growth factor 1 (acidic) 0.892
FGF10 fibroblast growth factor 10 0.420
FGFR1 fibroblast growth factor receptor 1 0.368
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.355
JAG1 jagged 1 0.245
HDAC4 histone deacetylase 4 0.144
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.109
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.101
BMPR1A bone morphogenetic protein receptor, type IA 0.098
PPARG peroxisome proliferator-activated receptor gamma 0.088
FGF2 fibroblast growth factor 2 (basic) 0.080
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.063
ESRRG estrogen-related receptor gamma 0.057
FSTL1 follistatin-like 1 0.053
EP300 E1A binding protein p300 0.050
CLOCK clock homolog (mouse) 0.047
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.041
FZD1 frizzled homolog 1 (Drosophila) 0.038
ARRDC3 arrestin domain containing 3 0.035
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.031
NOTCH3 notch 3 0.028
TJP1 tight junction protein 1 (zona occludens 1) 0.026
FGF7 fibroblast growth factor 7 0.025
BCL2L1 BCL2-like 1 0.023
HDAC9 histone deacetylase 9 0.023
CDK2 cyclin-dependent kinase 2 0.020
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.018
SPEN spen homolog, transcriptional regulator (Drosophila) 0.015
MAML1 mastermind-like 1 (Drosophila) 0.014
ESR1 estrogen receptor 1 0.014
ZHX1 zinc fingers and homeoboxes 1 0.013
TBX5 T-box 5 0.012
FRS2 fibroblast growth factor receptor substrate 2 0.012
CDK1 cyclin-dependent kinase 1 0.011
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.992
Pax3 paired box gene 3 0.962
Gata4 GATA binding protein 4 0.949
Bmp4 bone morphogenetic protein 4 0.927
Tbx3 T-box 3 0.925
Pitx2 paired-like homeodomain transcription factor 2 0.904
Gli3 GLI-Kruppel family member GLI3 0.895
Fgfr2 fibroblast growth factor receptor 2 0.870
Gli2 GLI-Kruppel family member GLI2 0.859
Tbx2 T-box 2 0.845
Shh sonic hedgehog 0.828
Notch1 Notch gene homolog 1 (Drosophila) 0.814
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.776
Efnb2 ephrin B2 0.771
Pitx1 paired-like homeodomain transcription factor 1 0.755
Hand2 heart and neural crest derivatives expressed transcript 2 0.743
Gata6 GATA binding protein 6 0.718
Per2 period homolog 2 (Drosophila) 0.650
Scn5a sodium channel, voltage-gated, type V, alpha 0.639
Foxc1 forkhead box C1 0.615
Fgf10 fibroblast growth factor 10 0.583
Nodal nodal 0.578
Zfpm2 zinc finger protein, multitype 2 0.527
Ntf3 neurotrophin 3 0.524
Bcl2 B-cell leukemia/lymphoma 2 0.493
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.455
Pou3f3 POU domain, class 3, transcription factor 3 0.449
Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 0.439
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.438
Hand1 heart and neural crest derivatives expressed transcript 1 0.432
Col13a1 collagen, type XIII, alpha 1 0.421
Fgf8 fibroblast growth factor 8 0.405
Twist2 twist homolog 2 (Drosophila) 0.389
Alx4 aristaless-like homeobox 4 0.387
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 0.380
Tgfb2 transforming growth factor, beta 2 0.369
Gdf5 growth differentiation factor 5 0.357
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.350
Bax BCL2-associated X protein 0.340
Smad6 MAD homolog 6 (Drosophila) 0.323
Fgf3 fibroblast growth factor 3 0.300
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.284
She src homology 2 domain-containing transforming protein E 0.279
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.265
Sox7 SRY-box containing gene 7 0.261
Jag1 jagged 1 0.260
Wt1 Wilms tumor 1 homolog 0.258
Zeb1 zinc finger E-box binding homeobox 1 0.245
Npas1 neuronal PAS domain protein 1 0.234
Gpc3 glypican 3 0.227
Nog noggin 0.218
Tbx1 T-box 1 0.215
Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.215
Pcdh12 protocadherin 12 0.213
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.207
Sox4 SRY-box containing gene 4 0.204
Meox2 mesenchyme homeobox 2 0.199
Dll1 delta-like 1 (Drosophila) 0.194
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.188
Foxf1a forkhead box F1a 0.186
Dll4 delta-like 4 (Drosophila) 0.182
Gli1 GLI-Kruppel family member GLI1 0.181
Foxg1 forkhead box G1 0.180
Rxra retinoid X receptor alpha 0.174
Ryr2 ryanodine receptor 2, cardiac 0.173
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.168
Pitx3 paired-like homeodomain transcription factor 3 0.168
Pax7 paired box gene 7 0.166
Foxc2 forkhead box C2 0.164
Isl1 ISL1 transcription factor, LIM/homeodomain 0.160
Fut2 fucosyltransferase 2 0.158
Atoh8 atonal homolog 8 (Drosophila) 0.157
Snai1 snail homolog 1 (Drosophila) 0.157
Wnt5a wingless-related MMTV integration site 5A 0.153
Npas2 neuronal PAS domain protein 2 0.148
Nos3 nitric oxide synthase 3, endothelial cell 0.142
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.142
Foxn1 forkhead box N1 0.142
Ephb2 Eph receptor B2 0.140
Myf5 myogenic factor 5 0.138
Lama5 laminin, alpha 5 0.137
Vegfa vascular endothelial growth factor A 0.137
Fgf9 fibroblast growth factor 9 0.134
Wnt2b wingless related MMTV integration site 2b 0.134
Trp63 transformation related protein 63 0.131
Notch2 Notch gene homolog 2 (Drosophila) 0.130
Gdnf glial cell line derived neurotrophic factor 0.128
Runx2 runt related transcription factor 2 0.127
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.126
Edn3 endothelin 3 0.125
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.111
Alx3 aristaless-like homeobox 3 0.111
Wnt3a wingless-related MMTV integration site 3A 0.111
Sox10 SRY-box containing gene 10 0.110
Msx1 homeobox, msh-like 1 0.110
Fgf18 fibroblast growth factor 18 0.109
Wnt10b wingless related MMTV integration site 10b 0.107
Fgfr4 fibroblast growth factor receptor 4 0.104
Dhh desert hedgehog 0.103
Pten phosphatase and tensin homolog 0.103
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism