The network for 'optic placode formation involved in camera type eye formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

optic placode formation involved in camera type eye formation

Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles.

Danio rerio
Name Description Probability Func Analog Organism
tbx1 T-box 1 0.995
wnt4a wingless-type MMTV integration site family, member 4a 0.993
wnt1 wingless-type MMTV integration site family, member 1 0.983
wnt3 wingless-type MMTV integration site family, member 3 0.964
sfrp1a secreted frizzled-related protein 1a 0.936
twist1a twist1a 0.926
wnt2 wingless-type MMTV integration site family member 2 0.861
foxa2 forkhead box A2 0.855
dkk1b dickkopf 1b 0.828
wnt5b wingless-type MMTV integration site family, member 5b 0.814
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.814
flh floating head 0.810
fzd7b frizzled homolog 7b 0.797
klf4 Kruppel-like factor 4 0.795
wnt10a wingless-type MMTV integration site family, member 10a 0.765
ephb4b eph receptor B4b 0.757
bmp2a bone morphogenetic protein 2a 0.748
bmp4 bone morphogenetic protein 4 0.732
wnt8b wingless-type MMTV integration site family, member 8b 0.708
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.692
fgf3 fibroblast growth factor 3 0.660
fgf17 fibroblast growth factor 17 0.624
hnf1ba HNF1 homeobox Ba 0.587
scube2 signal peptide, CUB domain, EGF-like 2 0.569
twist3 twist3 0.550
wnt9b wingless-type MMTV integration site family, member 9B 0.534
wnt11r wingless-type MMTV integration site family, member 11, related 0.534
sox2 SRY-box containing gene 2 0.526
lratb lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b) 0.516
dharma dharma 0.511
wnt10b wingless-type MMTV integration site family, member 10b 0.504
dag1 dystroglycan 1 0.484
hoxd4a homeo box D4a 0.484
ndr2 nodal-related 2 0.446
wnt3a wingless-type MMTV integration site family, member 3A 0.444
lft1 lefty1 0.432
wnt9a wingless-type MMTV integration site family, member 9A 0.420
sulf1 sulfatase 1 0.403
dbx1a developing brain homeobox 1a 0.393
wnt11 wingless-type MMTV integration site family, member 11 0.387
wnt7aa wingless-type MMTV integration site family, member 7Aa 0.377
pea3 ETS-domain transcription factor pea3 0.377
admp anti-dorsalizing morphogenic protein 0.366
spry2 sprouty homolog 2 0.361
gli1 GLI-Kruppel family member 1 0.344
notch3 notch homolog 3 0.343
lft2 lefty2 0.340
col11a2 collagen type XI alpha-2 0.327
frzb frizzled-related protein 0.315
zbtb4 zinc finger and BTB domain containing 4 0.269
lama5 laminin, alpha 5 0.267
wnt16 wingless-type MMTV integration site family, member 16 0.265
wnt7ba wingless-type MMTV integration site family, member 7Ba 0.264
wls wntless homolog (Drosophila) 0.260
gsc goosecoid 0.249
wif1 wnt inhibitory factor 1 0.249
igfbp3 insulin-like growth factor binding protein 3 0.241
map2k4a mitogen-activated protein kinase kinase 4a 0.229
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.211
hoxa13b homeo box A13b 0.199
has2 hyaluronan synthase 2 0.183
fgf10a fibroblast growth factor 10a 0.172
foxj1a forkhead box J1a 0.162
shhb sonic hedgehog b 0.162
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.158
fzd7a frizzled homolog 7a 0.158
cxcr4a chemokine (C-X-C motif) receptor 4a 0.156
smad3b MAD, mothers against decapentaplegic homolog 3b (Drosophila) 0.153
spry4 sprouty (Drosophila) homolog 4 0.153
lmo4a LIM domain only 4a 0.149
zfyve26 zinc finger, FYVE domain containing 26 0.147
gro2 groucho 2 0.144
nkx3.2 NK3 homeobox 2 0.143
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.140
tnfsf10l3 tumor necrosis factor (ligand) superfamily, member 10 like 3 0.140
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.139
fn1 fibronectin 1 0.135
fgf4 fibroblast growth factor 4 0.132
map2k4b mitogen-activated protein kinase kinase 4b 0.131
ntla no tail a 0.127
lhx1b LIM homeobox 1b 0.124
sox17 SRY-box containing gene 17 0.122
arl4ab ADP-ribosylation factor-like 4ab 0.116
bmp2b bone morphogenetic protein 2b 0.116
dact2 dapper homolog 2, antagonist of beta-catenin (xenopus) 0.115
osr2 odd-skipped related 2 (Drosophila) 0.114
gli2b GLI-Kruppel family member GLI2b 0.114
ihha Indian hedgehog homolog a 0.113
ptch2 patched 2 0.111
six2a sine oculis-related homeobox 2a 0.109
ptch1 patched 1 0.108
fbln1 fibulin 1 0.105
igf1ra insulin-like growth factor 1a receptor 0.102
si:dkey-273o13.1 si:dkey-273o13.1 0.099
wnt7bb wingless-type MMTV integration site family, member 7Bb 0.097
map2k7 mitogen-activated protein kinase kinase 7 0.096
amotl2a angiomotin like 2a 0.095
grem1a gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis) 0.095
il17rd interleukin 17 receptor D 0.094
znf711 zinc finger protein 711 0.094
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Dok1 docking protein 1 0.998
Dok2 docking protein 2 0.984
Inpp5d inositol polyphosphate-5-phosphatase D 0.966
Grb2 growth factor receptor bound protein 2 0.542
Dok3 docking protein 3 0.264
Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 0.194
Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.155
Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.090
Csk c-src tyrosine kinase 0.074
Shc1 src homology 2 domain-containing transforming protein C1 0.064
Gopc golgi associated PDZ and coiled-coil motif containing 0.024
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.021
Nck1 non-catalytic region of tyrosine kinase adaptor protein 1 0.017
Sykb spleen tyrosine kinase 0.016
Cbl Casitas B-lineage lymphoma 0.015
Pten phosphatase and tensin homolog 0.014
Trp53 transformation related protein 53 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism