IMP

Process View

Drosophila melanogaster

18 genes annotated in fly

Multi-species View

apical constriction

GO:0003383

The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in fly Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "apical constriction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "apical constriction" (in gray)

Name	Description	Probability	Func Analog Organism
crb	crumbs	0.896
f	forked	0.806
nyo	nyobe	0.660
m	miniature	0.632
sha	shavenoid	0.604
rok	Rho-kinase	0.362
tyn	trynity	0.256
baz	bazooka	0.253	Mouse
blot	bloated tubules	0.213
G-oalpha47A	G protein oalpha 47A	0.159	Fly
rempA	reduced mechanoreceptor potential A	0.145
Ggamma1	G protein gamma 1	0.119
kni	knirps	0.098
sv	shaven	0.089
norpA	no receptor potential A	0.089
zye	CG5847 gene product from transcript CG5847-RA	0.081
Tak1	TGF-beta activated kinase 1	0.078
par-6	CG5884 gene product from transcript CG5884-RA	0.071
sn	singed	0.065
SoxN	SoxNeuro	0.065
cta	concertina	0.065
ik2	IkappaB kinase-like 2	0.060
sec5	CG8843 gene product from transcript CG8843-RA	0.054
tilB	touch insensitive larva B	0.053
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.053
Su(var)2-10	Suppressor of variegation 2-10	0.051
btv	beethoven	0.046
par-1	CG8201 gene product from transcript CG8201-RA	0.045
ase	asense	0.045
sina	seven in absentia	0.044
flw	flapwing	0.043
frc	fringe connection	0.043
Lis-1	Lissencephaly-1	0.042
plexB	plexin B	0.041
Act88F	Actin 88F	0.040
chic	chickadee	0.040
fj	four-jointed	0.040
ara	araucan	0.039
Doc2	Dorsocross2	0.038
Krn	Keren	0.037
ap	apterous	0.037
aret	arrest	0.036
Poxn	Pox neuro	0.035
kuz	kuzbanian	0.034
lap	like-AP180	0.034
sec23	CG1250 gene product from transcript CG1250-RA	0.033
unc	uncoordinated	0.031
Tm1	Tropomyosin 1	0.029
caup	caupolican	0.029
Su(Tpl)	CG32217 gene product from transcript CG32217-RB	0.029
grk	gurken	0.028
Sb	Stubble	0.028
Tre1	trapped in endoderm-1	0.028
Awh	Arrowhead	0.028
nompB	no mechanoreceptor potential B	0.027
dy	dusky	0.027	Fly
gfA	giant fibre A	0.027
ro	rough	0.026
flr	flare	0.025
mew	multiple edematous wings	0.025
shg	shotgun	0.024
in	inturned	0.024
cdi	center divider	0.023
Syx7	Syntaxin 7	0.023
mas	masquerade	0.023
drm	drumstick	0.022
Z600	CG17962 gene product from transcript CG17962-RA	0.022
milt	milton	0.022
mey	morpheyus	0.022
Mcr	Macroglobulin complement-related	0.022
pdm2	POU domain protein 2	0.022
CG8155	CG8155 gene product from transcript CG8155-RA	0.021
Arc-p34	CG10954 gene product from transcript CG10954-RA	0.021
m6	E(spl) region transcript m6	0.021
Patj	CG12021 gene product from transcript CG12021-RC	0.021
Spn100A	Serpin 100A	0.021
scrib	scribbled	0.021
CG5873	CG5873 gene product from transcript CG5873-RA	0.021
drk	downstream of receptor kinase	0.021
fln	flightin	0.020
mmy	mummy	0.020
usp	ultraspiracle	0.019
sgl	sugarless	0.019
Atg7	Autophagy-specific gene 7	0.019
Act5C	Actin 5C	0.019
myoglianin	CG1838 gene product from transcript CG1838-RD	0.019
al	aristaless	0.019
arr	arrow	0.019
Sop2	Suppressor of profilin 2	0.019
pwn	pawn	0.019
shrb	shrub	0.018
os	outstretched	0.018
unk	unkempt	0.018
insc	inscuteable	0.018
fng	fringe	0.018
Rapgap1	CG34374 gene product from transcript CG34374-RD	0.018
vas	vasa	0.018
loco	locomotion defects	0.018
CG31121	CG31121 gene product from transcript CG31121-RA	0.018
inv	invected	0.018
inx2	innexin 2	0.018
Ser	Serrate	0.017
tai	taiman	0.017
so	sine oculis	0.017
Cul-5	Cullin-5	0.016
edl	ETS-domain lacking	0.016
Wnt4	Wnt oncogene analog 4	0.016
RhoGDI	CG7823 gene product from transcript CG7823-RA	0.015
mwh	multiple wing hairs	0.015
por	porcupine	0.015
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.015
gish	gilgamesh	0.015
lic	licorne	0.015
Mes2	CG11100 gene product from transcript CG11100-RB	0.015
yu	CG3249 gene product from transcript CG3249-RA	0.015
trk	trunk	0.015
Traf6	TNF-receptor-associated factor 6	0.015	Fly
Wnt2	Wnt oncogene analog 2	0.014
Msi	Male-specific insect derived growth factor	0.014
Adar	Adenosine deaminase acting on RNA	0.014
Mtl	Mig-2-like	0.014
egr	eiger	0.014
CG9867	CG9867 gene product from transcript CG9867-RA	0.014
neo	neyo	0.014
Rab11	Rab-protein 11	0.013
chp	chaoptic	0.013
CG10395	CG10395 gene product from transcript CG10395-RA	0.013
CG1273	CG1273 gene product from transcript CG1273-RB	0.013
pyd	polychaetoid	0.013
Actbeta	Activin-beta	0.013
kibra	kibra ortholog	0.013
Cby	Chibby	0.013
Pph13	PvuII-PstI homology 13	0.013
Sgs8	Salivary gland secretion 8	0.013
imd	immune deficiency	0.013
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.013
RanBPM	Ran-binding protein M	0.013
CG12026	CG12026 gene product from transcript CG12026-RB	0.013
spz6	spatzle 6	0.012
Tsc1	CG6147 gene product from transcript CG6147-RA	0.012
CG32556	CG32556 gene product from transcript CG32556-RB	0.012
Klp64D	Kinesin-like protein at 64D	0.012
Gprk2	G protein-coupled receptor kinase 2	0.012
CG42247	CG42247 gene product from transcript CG42247-RC	0.012
sens	senseless	0.012
egh	egghead	0.012
ric8a	CG15797 gene product from transcript CG15797-RA	0.012
nito	spenito	0.012
dve	defective proventriculus	0.012
drl	derailed	0.012
HLH4C	Helix loop helix protein 4C	0.012
PGRP-SC1a	CG14746 gene product from transcript CG14746-RA	0.011
bib	big brain	0.011
pigs	pickled eggs	0.011
Mrtf	Myocardin-related transcription factor	0.011
Wnt5	Wnt oncogene analog 5	0.011
disp	dispatched	0.011
CG6472	CG6472 gene product from transcript CG6472-RA	0.011
eater	CG6124 gene product from transcript CG6124-RB	0.011
nudE	CG8104 gene product from transcript CG8104-RB	0.011
melt	melted	0.011
Btk29A	Btk family kinase at 29A	0.011
CG9090	CG9090 gene product from transcript CG9090-RA	0.011
msn	misshapen	0.011
Galpha49B	G protein alpha49B	0.011	Fly
CG13216	CG13216 gene product from transcript CG13216-RA	0.011
mira	miranda	0.011
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.010
CG14960	CG14960 gene product from transcript CG14960-RA	0.010
Nplp4	Neuropeptide-like precursor 4	0.010
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.010
CG12009	CG12009 gene product from transcript CG12009-RA	0.010
nullo	CG14426 gene product from transcript CG14426-RB	0.010
CG14607	CG14607 gene product from transcript CG14607-RB	0.010
vir	virilizer	0.010
bip1	CG7574 gene product from transcript CG7574-RA	0.010
l(2)gl	lethal (2) giant larvae	0.010
CG1756	CG1756 gene product from transcript CG1756-RA	0.010