IMP

Process View

Homo sapiens

20 genes annotated in human

positive regulation of wound healing

Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of wound healing"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of wound healing" (in gray)

Name	Description	Probability	Func Analog Organism
RHOA	ras homolog gene family, member A	0.991	Fly
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.893
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.866
VEGFA	vascular endothelial growth factor A	0.843	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.839
IQGAP1	IQ motif containing GTPase activating protein 1	0.797
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.778
ARHGAP1	Rho GTPase activating protein 1	0.738
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.647
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.611	Fly
NCF1	neutrophil cytosolic factor 1	0.608
MAPK1	mitogen-activated protein kinase 1	0.568	Fly
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.560
NCOA1	nuclear receptor coactivator 1	0.512
NRP1	neuropilin 1	0.469
PLAUR	plasminogen activator, urokinase receptor	0.416
NCF2	neutrophil cytosolic factor 2	0.401
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.340	Fly
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.336	Fly
ARHGAP10	Rho GTPase activating protein 10	0.310
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.268	Human
PLAU	plasminogen activator, urokinase	0.242	Human
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.241
NCF4	neutrophil cytosolic factor 4, 40kDa	0.226
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.202
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.162
S100A4	S100 calcium binding protein A4	0.154
EGFR	epidermal growth factor receptor	0.153	Fly
FGA	fibrinogen alpha chain	0.139
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.134	Fly
TGFB1	transforming growth factor, beta 1	0.127
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.108
RALBP1	ralA binding protein 1	0.102
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.099
MAPK14	mitogen-activated protein kinase 14	0.093
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.090
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.087
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.086	Human
MPDZ	multiple PDZ domain protein	0.086
PLG	plasminogen	0.083
MAP2K1	mitogen-activated protein kinase kinase 1	0.083
PLCG1	phospholipase C, gamma 1	0.082
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.076
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.075	Mouse
EMP3	epithelial membrane protein 3	0.075
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.074
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.073
PLAT	plasminogen activator, tissue	0.070	Human
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.066
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.063
PDGFC	platelet derived growth factor C	0.062
CYBA	cytochrome b-245, alpha polypeptide	0.061
ALB	albumin	0.061
KEAP1	kelch-like ECH-associated protein 1	0.059
MSN	moesin	0.058
PTPRB	protein tyrosine phosphatase, receptor type, B	0.055
FGB	fibrinogen beta chain	0.051
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.051
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.050
ABI1	abl-interactor 1	0.049
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.048
RALB	v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)	0.046	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.045	Rat
PTEN	phosphatase and tensin homolog	0.044
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.042
TTN	titin	0.042
EZR	ezrin	0.041
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.041
PGF	placental growth factor	0.040	Human
PEA15	phosphoprotein enriched in astrocytes 15	0.040
C1S	complement component 1, s subcomponent	0.040
PRKCD	protein kinase C, delta	0.039
ENG	endoglin	0.038
ILK	integrin-linked kinase	0.038
PRKCA	protein kinase C, alpha	0.035	Human
CD320	CD320 molecule	0.034
DLG4	discs, large homolog 4 (Drosophila)	0.034
THBS1	thrombospondin 1	0.032
COL1A1	collagen, type I, alpha 1	0.032
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.032
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.031
COL4A1	collagen, type IV, alpha 1	0.031
F3	coagulation factor III (thromboplastin, tissue factor)	0.029
LY96	lymphocyte antigen 96	0.029
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.029
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.029
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.028
PDGFA	platelet-derived growth factor alpha polypeptide	0.028	Human
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.027
NCOA3	nuclear receptor coactivator 3	0.027
TIMP1	TIMP metallopeptidase inhibitor 1	0.027
ARHGAP26	Rho GTPase activating protein 26	0.027
RALGDS	ral guanine nucleotide dissociation stimulator	0.027
SMAD2	SMAD family member 2	0.026
TICAM2	toll-like receptor adaptor molecule 2	0.026
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.026
C1R	complement component 1, r subcomponent	0.025
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.025
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.024
KNG1	kininogen 1	0.024
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.023
DUSP1	dual specificity phosphatase 1	0.023
RHOC	ras homolog gene family, member C	0.022	Fly
PTPRC	protein tyrosine phosphatase, receptor type, C	0.022
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.021
S100A2	S100 calcium binding protein A2	0.021
COL5A1	collagen, type V, alpha 1	0.021
GAB1	GRB2-associated binding protein 1	0.021
TSG101	tumor susceptibility gene 101	0.021
TIMP3	TIMP metallopeptidase inhibitor 3	0.020
VTN	vitronectin	0.020
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.020
HDAC6	histone deacetylase 6	0.019
TGFB3	transforming growth factor, beta 3	0.019
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.019
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.019
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.019
TGFBR1	transforming growth factor, beta receptor 1	0.018
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.018
CAPNS1	calpain, small subunit 1	0.018
DLG2	discs, large homolog 2 (Drosophila)	0.018
TRIM9	tripartite motif containing 9	0.018
AXL	AXL receptor tyrosine kinase	0.018
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.018
LPA	lipoprotein, Lp(a)	0.018	Human
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.017
CAV1	caveolin 1, caveolae protein, 22kDa	0.017
CD151	CD151 molecule (Raph blood group)	0.017
DLG3	discs, large homolog 3 (Drosophila)	0.017
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.017
GAB2	GRB2-associated binding protein 2	0.017
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.017
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.017
BCL6	B-cell CLL/lymphoma 6	0.017
AKNA	AT-hook transcription factor	0.016
FKBP8	FK506 binding protein 8, 38kDa	0.016
C8B	complement component 8, beta polypeptide	0.016
PEBP1	phosphatidylethanolamine binding protein 1	0.016
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.016
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.016
MAPK3	mitogen-activated protein kinase 3	0.016	Fly
TGFBI	transforming growth factor, beta-induced, 68kDa	0.016
CREBBP	CREB binding protein	0.016
ITIH2	inter-alpha (globulin) inhibitor H2	0.015
SOS1	son of sevenless homolog 1 (Drosophila)	0.015
COL1A2	collagen, type I, alpha 2	0.015
ORM1	orosomucoid 1	0.015
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.015
PAWR	PRKC, apoptosis, WT1, regulator	0.015
RANBP9	RAN binding protein 9	0.015
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.014
F13A1	coagulation factor XIII, A1 polypeptide	0.014
INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	0.014
DDR2	discoidin domain receptor tyrosine kinase 2	0.014
F10	coagulation factor X	0.014	Human
PRODH2	proline dehydrogenase (oxidase) 2	0.013
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.013	Human
FYN	FYN oncogene related to SRC, FGR, YES	0.013
BTK	Bruton agammaglobulinemia tyrosine kinase	0.013
PLD1	phospholipase D1, phosphatidylcholine-specific	0.013
HSPG2	heparan sulfate proteoglycan 2	0.013
BAD	BCL2-associated agonist of cell death	0.013
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.013
DUSP3	dual specificity phosphatase 3	0.013
ENPP5	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	0.013
RHOU	ras homolog gene family, member U	0.012
PROCR	protein C receptor, endothelial	0.012
AHSG	alpha-2-HS-glycoprotein	0.012
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.012
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.012
TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.012
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.012
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.012
SH2B3	SH2B adaptor protein 3	0.012
CD81	CD81 molecule	0.012
SRPX	sushi-repeat containing protein, X-linked	0.012
PLXNB1	plexin B1	0.012
TAT	tyrosine aminotransferase	0.012
CTTN	cortactin	0.012
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.012
ATF2	activating transcription factor 2	0.012
FLT4	fms-related tyrosine kinase 4	0.011
IGF1	insulin-like growth factor 1 (somatomedin C)	0.011
COL2A1	collagen, type II, alpha 1	0.011
TSPAN4	tetraspanin 4	0.011
PDE4DIP	phosphodiesterase 4D interacting protein	0.011
ARRDC3	arrestin domain containing 3	0.011
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.011
EIF2AK3	eukaryotic translation initiation factor 2-alpha kinase 3	0.011
USP33	ubiquitin specific peptidase 33	0.011
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.011
ECSIT	ECSIT homolog (Drosophila)	0.011
PTHLH	parathyroid hormone-like hormone	0.011
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.011
STC1	stanniocalcin 1	0.011
PEBP4	phosphatidylethanolamine-binding protein 4	0.011
TNC	tenascin C	0.011
COL3A1	collagen, type III, alpha 1	0.011
CHRD	chordin	0.011
SMAD7	SMAD family member 7	0.011
NRG1	neuregulin 1	0.011
HCFC1R1	host cell factor C1 regulator 1 (XPO1 dependent)	0.011
CAV2	caveolin 2	0.010
CDH5	cadherin 5, type 2 (vascular endothelium)	0.010
CTNND1	catenin (cadherin-associated protein), delta 1	0.010
APOC3	apolipoprotein C-III	0.010
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.010
SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.010
VEGFC	vascular endothelial growth factor C	0.010	Human
AMT	aminomethyltransferase	0.010
F2	coagulation factor II (thrombin)	0.010